Integrating Motivational Interviewing in Pain Neuroscience Education for People With Chronic Pain: A Practical Guide for Clinicians

Nijs, Jo; Wijma, Amarins J; Willaert, Ward; Huysmans, Eva; Mintken, Paul; Smeets, Rob; Goossens, Mariëlle; van Wilgen, C Paul; Van Bogaert, Wouter; Louw, Adriaan; Cleland, Josh; Donaldson, Megan

doi:10.1093/ptj/pzaa021

Cited by 97Musculoskeletal pain and rehabilitationPain Management and TreatmentPain Mechanisms and Treatments

Integrating Motivational Interviewing in Pain Neuroscience Education for People With Chronic Pain: A Practical Guide for Clinicians

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Nijs, Jo, Wijma, Amarins J, Willaert, Ward, Huysmans, Eva, Mintken, Paul, Smeets, Rob, Goossens, Mariëlle, van Wilgen, C Paul +4 more·2020·Physical Therapy

DOI 10.1093/ptj/pzaa021

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Abstract

Pain neuroscience education (PNE) and motivational interviewing (MI) have been widely implemented and tested in the field of chronic pain management, and both strategies have been shown to be effective in the short term (small effect sizes) for the management of chronic pain. PNE uses contemporary pain science to educate patients about the biopsychosocial nature of the chronicity of their pain experience. The goal of PNE is to optimize patients’ pain beliefs/perceptions to facilitate the acquisition of adaptive pain–coping strategies. MI, on the other hand, is a patient-centered communication style for eliciting and enhancing motivation for behavior change by shifting the patient away from a state of indecision or uncertainty. Conceptually, PNE and MI appear to be complementary interventions, with complementary rather than overlapping effects; MI primarily improves cognitive and behavioral awareness and, potentially, adherence to treatment principles, whereas PNE potentially increases pain knowledge/beliefs, awareness, and willingness to explore psychological factors that are potentially associated with pain. Therefore, combining PNE with MI might lead to improved outcomes with larger and longer-lasting effect sizes. The combined use of PNE and MI in patients having chronic pain is introduced here, along with a description of how clinicians might be able to integrate PNE and MI in the treatment of patients experiencing chronic pain. Clinical trials are needed to examine whether combining PNE with MI is superior to PNE or MI alone for improving pain and quality of life in patients having chronic pain.

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Through PNE a person may gain insight that helps them shift from a perspective of pain as equal to tissue damage to a broader understanding of pain as a protective and adaptive response that may be activated by a wide array of body, mind, and environmental stimuli.
“Through PNE the person may gain insight that helps them shift from a perspective of pain as equal to tissue damage to a more broad understanding of pain as a protective and adaptive response which may be activated from a wide array of body, mind, and environmental stimuli.28,50-53”
From Remotely Delivered Psychologically Informed Mindful Movement Physical Therapy for Pain Care: A Framework for Operationalization (2023) · cites this paper as [52]
Split into 2 atoms — 1 confirmed, 1 partially supported, 0 disputed, 0 misattributed, 0 unverifiable. Expand the claim to see per-atom verdicts.
Experimental — accuracy not yet measured
Pain neuroscience education is an integral part of physical therapy pain care.
“Pain neuroscience education (PNE) is an integral part of physical therapy pain care.”
From Remotely Delivered Psychologically Informed Mindful Movement Physical Therapy for Pain Care: A Framework for Operationalization (2023) · cites this paper as [52]
The introduction (p. 2) says PNE is widely implemented in chronic pain management, and “Motivational Interviewing Plus Explaining Pain” (p. 6) includes physical therapists among clinicians who can use it. The paper does not establish PNE as an integral part of physical therapy pain care generally; it describes PNE as a treatment concept to tailor to patients rather than a standard intervention. (LLM, conf=0.84)
Experimental — accuracy not yet measured
Integration of PNE with active interventions and cognitive based approaches demonstrates a synergistic and larger effect for clinically important improvements in pain, disability, kinesiophobia, and function.
“Integration of PNE with active interventions and cognitive based approaches demonstrates a synergistic and larger effect for clinically important improvements in pain and disability, kinesiophobia, and function.20,51,52,55”
From Remotely Delivered Psychologically Informed Mindful Movement Physical Therapy for Pain Care: A Framework for Operationalization (2023) · cites this paper as [52]
The Evidence Supporting the Use of PNE section (p. 4) says combining PNE with cognition-targeted exercise has a synergistic effect, with medium-to-large effects sustained for one year in patients with chronic spinal pain. It does not establish clinically important improvements in each listed outcome—pain, disability, kinesiophobia, and function—from the combination. The Motivational Interviewing Plus Explaining Pain section (p. 4) instead identifies clinically meaningful kinesiophobia improvement with PNE and says pain and disability improvements following PNE alone were not clinically important. (LLM, conf=0.88)
Experimental — accuracy not yet measured
Using MI with PNE has shown positive effects for the management of chronic pain and adherence to treatment and is well-aligned with a PiPT acceptance and mindfulness approach to pain care.
“Using MI with PNE has shown positive effects for the management of chronic pain and adherence to treatment and is well-aligned with a PiPT acceptance and mindfulness approach to pain care. 52”
From Remotely Delivered Psychologically Informed Mindful Movement Physical Therapy for Pain Care: A Framework for Operationalization (2023) · cites this paper as [52]
The Conclusion (p. 7) says MI and PNE have each shown some short-term benefit in chronic pain management, with MI primarily improving treatment adherence. It says combining them may improve outcomes but that clinical trials are needed; it also links the combined approach to acceptance-based interventions, without addressing mindfulness or PiPT specifically. (LLM, conf=0.88)
Experimental — accuracy not yet measured
The success of delivery of PiPT and PNE has been shown to be impacted by the PT's confidence and comfort with the program as well as the therapist having the qualities necessary to implement patient-centered care.
“The success of delivery of PiPT and PNE has been shown to be impacted by the PT’s confidence and comfort with the program as well as the therapist having the qualities necessary to implement patient-centered care.20,28,32,35,44,52”
From Remotely Delivered Psychologically Informed Mindful Movement Physical Therapy for Pain Care: A Framework for Operationalization (2023) · cites this paper as [52]
The section “Evidence Supporting the Use of PNE in People With Chronic Pain” (p. 5) says therapists’ interpersonal and communication skills influence the therapeutic relationship and describes qualities needed for patient-centered care. “Motivational Interviewing Plus Explaining Pain” (p. 6) also lists skills needed to deliver PNE with motivational interviewing. Neither passage establishes that PTs’ confidence or comfort with a program affects delivery success, and the paper does not address PiPT in the passages found. (LLM, conf=0.84)
Experimental — accuracy not yet measured

PNE supports a reconceptualization of pain, including helping to reframe beliefs around fear of movement or other adverse relationships to pain that inhibit a return to function or negatively impact quality of life.
“PNE supports a reconceptualization of pain including helping to reframe beliefs around fear of movement, or other adverse relationships to pain, that inhibit a return to function and/or negatively impact quality of life.20,28,50-52”
From Remotely Delivered Psychologically Informed Mindful Movement Physical Therapy for Pain Care: A Framework for Operationalization (2023) · cites this paper as [52]
This guiding style provides insight to individualize PNE, to ascertain beliefs that may be obstacles to learning and change, and to identify specific interventions aligning with the person's preferences and values.
“This guiding style of communication provides insight to individualize PNE (e.g. examples to draw out and build from), to ascertain beliefs that may be obstacles to learning and change, and to identify specific interventions aligning with the person’s preferences and values.20,52,53”
From Remotely Delivered Psychologically Informed Mindful Movement Physical Therapy for Pain Care: A Framework for Operationalization (2023) · cites this paper as [52]
MI can match language to the person's stage of readiness and willingness to change to support knowledge-sharing about pain, awareness of one's beliefs, and developing insight into biopsychosocial factors for safety and danger which may affect the threat value of pain.
“MI can match language to the person’s stage of readiness and willingness to change to support knowledge-sharing about pain, awareness of one’s beliefs, and developing insight into BPS factors for safety and danger which may affect the threat value of pain. 52”
From Remotely Delivered Psychologically Informed Mindful Movement Physical Therapy for Pain Care: A Framework for Operationalization (2023) · cites this paper as [52]
Motivational Interviewing is a patient-centered communication style supportive of an empowering therapeutic alliance that allows personal insight for intrinsic motivation for behavior change.
“Motivational Interviewing (MI) is a patient-centered communication style supportive of an empowering therapeutic alliance to allow personal insight for intrinsic motivation for behavior change.20,52,57”
From Remotely Delivered Psychologically Informed Mindful Movement Physical Therapy for Pain Care: A Framework for Operationalization (2023) · cites this paper as [52]
Shifting the mode of delivery from more didactic approaches to emphasizing patient-centered communication may foster receptivity to examine one's beliefs, support willingness and readiness for change, and explore personal relevance.
“Shifting the mode of delivery from more didactic approaches to emphasizing patient-centered communication may foster receptivity to examine one’s beliefs, support willingness and readiness for change, and to explore personal relevance.20,28,50,52,56”
From Remotely Delivered Psychologically Informed Mindful Movement Physical Therapy for Pain Care: A Framework for Operationalization (2023) · cites this paper as [52]

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Amiri, P., Kazemian, E., Mansouri‐Tehrani, M. M., Khalili, A., & Amouzegar, A. (2018) · Systematic Reviews · doi:10.1186/s13643-018-0814-6 · Cited by 5 · see citing works

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4 Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet . 2015;386:743-800.

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A critical review of the biopsychosocial model of low back pain care: time for a new approach?
Mescouto, K. A., Olson, R. E., Hodges, P. W., & Setchell, J. (2020) · Disability and Rehabilitation · doi:10.1080/09638288.2020.1851783 · Cited by 259 · see citing works
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Neuralgic amyotrophy
IJspeert, J., Janssen, R. M. J., & van Alfen, N. (2021) · Current Opinion in Neurology · doi:10.1097/wco.0000000000000968 · Cited by 82 · see citing works
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Coninx, S., & Stilwell, P. (2021) · Synthese · doi:10.1007/s11229-021-03142-3 · Cited by 75 · see citing works
Personalized Multimodal Lifestyle Intervention as the Best-Evidenced Treatment for Chronic Pain: State-of-the-Art Clinical Perspective
Nijs, J., Malfliet, A., Roose, E. C. S., Lahousse, A., Bogaert, W. V., Johansson, E., Runge, N., Goossens, Z., Labie, C., Bilterys, T., et al. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13030644 · Cited by 63 · see citing works
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Lifestyle and Chronic Pain in the Pelvis: State of the Art and Future Directions
Gutke, A., Sundfeldt, K., & Baets, L. D. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10225397 · Cited by 45 · see citing works
The Biology of Chronic Pain and Its Implications for Pain Neuroscience Education: State of the Art
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Effectiveness of a Multicomponent Treatment based on Pain Neuroscience Education, Therapeutic Exercise, Cognitive Behavioural Therapy, and Mindfulness in Patients with Fibromyalgia (FIBROWALK study): A Randomized Controlled Trial.Preprint
Serrat, M., Sanabria‐Mazo, J. P., Almirall, M., Musté, M., Feliu‐Soler, A., Méndez-Ulrich, J. L., Sanz, A., & Luciano, J. V. (2020) · doi:10.31234/osf.io/kj8sp · Cited by 35 · see citing works
Unraveling the role of fear and avoidance behavior in chronic musculoskeletal pain: from theory to physical therapy clinical practice
Alaiti, R. K., dos Reis, F. J. J., Sanchez, T. A., Cañeiro, J. P., & Meulders, A. (2025) · Brazilian Journal of Physical Therapy · doi:10.1016/j.bjpt.2025.101197 · Cited by 35 · see citing works
Ronald Melzack Award Lecture: Putting the brain to work in cognitive behavioral therapy for chronic pain
Thorn, B. E. (2020) · Pain · doi:10.1097/j.pain.0000000000001839 · Cited by 30 · see citing works
Psychological Interventions for Pediatric Headache Disorders: A 2021 Update on Research Progress and Needs
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Neuralgic amyotrophy: An update in evaluation, diagnosis, and treatment approaches
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Physiotherapy support for self-management of persisting musculoskeletal pain disorders
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Striving for better outcomes of treating chronic pain: integrating behavioural change strategies before, during, and after modern pain science education
Roose, E. C. S., Nijs, J., & Moseley, G. L. (2023) · Brazilian Journal of Physical Therapy · doi:10.1016/j.bjpt.2023.100578 · Cited by 19 · see citing works
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Effects of Manual Therapy Plus Pain Neuroscience Education with Integrated Motivational Interviewing in Individuals with Chronic Non-Specific Low Back Pain: A Randomized Clinical Trial Study
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Effectiveness, cost-utility and physiological underpinnings of the FIBROWALK multicomponent therapy in online and outdoor format in individuals with fibromyalgia: Study protocol of a randomized, controlled trial (On&Out study)
Serrat, M., Ferrés, S., Auer, W., Almirall, M., Lluch, E., D’Amico, F., Maes, M. H. J., Lorente, S., Navarrete, J., Montero‐Marín, J., et al. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.1046613 · Cited by 14 · see citing works
Self-citation
Effect of pain neuroscience education+ (PNE+) in people with different mechanisms of chronic pain: A systematic review and meta-analysis
Tatikola, S. P., Natarajan, V., Amaravadi, S. K., Desai, V. K., Asirvatham, A. R., & Nagaraja, R. (2024) · Journal of Bodywork and Movement Therapies · doi:10.1016/j.jbmt.2024.11.016 · Cited by 14 · see citing works
The effect of mindfulness and motivational interviewing along with neuromuscular exercises on pain, function, and balance of women affected by knee osteoarthritis: a rater-blinded randomized controlled clinical trial
Chaharmahali, L., Gandomi, F., Yalfani, A., & Fazaeli, A. (2023) · Disability and Rehabilitation · doi:10.1080/09638288.2023.2228691 · Cited by 13 · see citing works
The effect of a pain educational video intervention upon child pain‐related outcomes: A randomized controlled study
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Nocebo and Placebo Effects and Their Implications in Psychotherapy
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Weight management communications in idiopathic intracranial hypertension: challenges and recommendations from the patients’ perspective
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Perceived factors influencing the success of pain neuroscience education in chronic musculoskeletal pain: a meta-synthesis of qualitative studies
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Remotely Delivered Psychologically Informed Mindful Movement Physical Therapy for Pain Care: A Framework for Operationalization
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“20,51,52,55 Integration of mind-fulness and acceptance based approaches may help provide insight into BPS contributors to pain and change perceived threat and activations for danger thereby in ﬂ uencing pain catastrophizing and activity-related fear.”
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Pain revolution in the public health system: Active coping strategies for chronic pain unit
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Integrative Treatment Strategies for Chronic Back Pain: A Literature Review with Clinical Recommendations
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The Effectiveness of Active Learning Approaches in a Pain Education Curriculum Within a Physical Therapy Program
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Autoimmune polyneuropathies
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Pain neuroscience education and motor imagery‐based exercise protocol for patients with fibromyalgia: A randomized controlled trial
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Combining Cognitive Behavioral Therapy for Insomnia and Chronic Spinal Pain Within Physical Therapy: A Practical Guide for the Implementation of an Integrated Approach
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Clinical prediction model for interdisciplinary biopsychosocial rehabilitation in osteoarthritis patients
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Interprofessional Active Learning for Chronic Pain: Transforming Student Learning From Recall to Application
Helms, J. T., Frankart, L. M., Bradner, M. K., Ebersole, J., Regan, B., & Crouch, T. B. (2023) · Journal of Medical Education and Curricular Development · doi:10.1177/23821205231221950 · Cited by 8 · see citing works
Physiotherapists’ knowledge, attitude and practice behavior to prevent chronification in patients with non-specific, non-traumatic, acute- and subacute neck pain: A qualitative study
Verwoerd, M. J., Wittink, H. M., Goossens, M. E. J. B., Maissan, F., & Smeets, R. (2021) · Musculoskeletal Science and Practice · doi:10.1016/j.msksp.2021.102493 · Cited by 8 · see citing works
Self-citation
Thoughts on Pain, Physical Activity, and Body in Patients With Recurrent Low Back Pain and Fear: An Interview Study
André, M., & Lundberg, M. (2022) · Physical Therapy · doi:10.1093/ptj/pzab275 · Cited by 8 · see citing works
Effectiveness of motivational interviewing plus cognitive behavioral therapy vs shared decision making for voluntary opioid tapering in patients with chronic pain: the INSPIRE randomized pragmatic trial
Mccormack, L. A., Edlund, M. J., Thomas, S., Wu, L.-T. T., Chelminski, P. R., Archer, K. R., Wagner, L., Hirsch, S. C., Thompson, J. E., Dolor, R. J., et al. (2025) · Pain Medicine · doi:10.1093/pm/pnaf049 · Cited by 6 · see citing works
Clinician perspectives on postamputation pain assessment and rehabilitation interventions
Rich, T. L., Falbo, K. J., Phelan, H. L., Gravely, A. A., Krebs, E. E., Finn, J. A., Matsumoto, M. E., Muschler, K., Olney, C. M., Kiecker, J., et al. (2023) · Prosthetics and Orthotics International · doi:10.1097/pxr.0000000000000284 · Cited by 6 · see citing works
Hard Flaccid Syndrome: A Biopsychosocial Management Approach with Emphasis on Pain Management, Exercise Therapy and Education
Billis, E. V., Kontogiannis, S., Tsounakos, S., Konstantinidou, E., & Giannitsas, K. (2023) · Healthcare · doi:10.3390/healthcare11202793 · Cited by 6 · see citing works
SECCION IX. Síndrome Post COVID-19: complicaciones tardías y rehabilitación
Saavedra, C. (2021) · Infectio · doi:10.22354/in.v25i4.979 · Cited by 8 · see citing works
Pain science education for children living with and beyond cancer: Challenges and research agenda
Rheel, E., Heathcote, L. C., ten Bosch, J. V. D. W., Schulte, F., & Pate, J. W. (2022) · Pediatric Blood & Cancer · doi:10.1002/pbc.29783 · Cited by 6 · see citing works
Letter to the editor: chronic pain tidal wave after COVID-19: are you ready?
Louw, A. (2020) · Physiotherapy Theory and Practice · doi:10.1080/09593985.2020.1840717 · Cited by 6 · see citing works
Self-citation
Contributors to Adherence to Exercise Therapy in Non-Specific Chronic Low Back Pain: A Systematic Review of Qualitative and Quantitative Research
Meuwissen, I., Vanderstraeten, R., Roussel, N. A., Meeus, M., Eetvelde, J. V., Meus, T., Timmermans, A. A. A., & Verbrugghe, J. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14176251 · Cited by 6 · see citing works
Design of a Multicenter Randomized Controlled Trial comparing the effectiveness of shared decision making versus motivational interviewing plus cognitive behavioral therapy for voluntary opioid tapering: The INSPIRE study protocol
Edlund, M. J., Thomas, S., Wagner, L., Thompson, J. E., Wu, L.-T. T., Dolor, R. J., Chelminski, P. R., Ives, T. J., Archer, K. R., Dewey, C. M., et al. (2023) · Contemporary Clinical Trials · doi:10.1016/j.cct.2023.107410 · Cited by 5 · see citing works
Novel motivational interviewing‐based intervention improves engagement in physical activity and readiness to change among adolescents with chronic pain
Forgács‐Kristóf, K., Ádám, S., Vargay, A., & Major, J. (2024) · Health Expectations · doi:10.1111/hex.14031 · Cited by 5 · see citing works
Pain Neuroscience Education for Depression: A Pilot Study
Louw, A., Louw, A., Wendling, E., Hawk, D., Sturdevant, N., Louw, H., & Farrell, K. P. (2021) · Psychological Disorders and Research · doi:10.31487/j.pdr.2021.02.01 · Cited by 4 · see citing works
Self-citation
Pain Neuroscience Education Versus Biomedical Pain Education with Exercise in Primary Dysmenorrhea: A Randomized Controlled Trial
Erol, B. N., Gürşen, C., Mümüşoğlu, S., & Özgül, S. (2025) · Healthcare · doi:10.3390/healthcare13161954 · Cited by 3 · see citing works
Early Identification and Management of Pain Catastrophizing in Primary Care
Lalchun, K., & Duff, E. (2025) · The Journal for Nurse Practitioners · doi:10.1016/j.nurpra.2025.105436 · Cited by 3 · see citing works
Experience-based design: Empowering individuals while they wait for interprofessional chronic pain care
Bosma, R. L., Bisson, E. J., Cooper, L., Salomons, T. V., Galica, J., & Wilson, R. A. (2023) · Patient Education and Counseling · doi:10.1016/j.pec.2023.107623 · Cited by 3 · see citing works
Pain Neuroscience Education in management of non-traumatic neck pain: a scoping review
Opara, M., & Kozinc, Ž. (2023) · European Journal of Physiotherapy · doi:10.1080/21679169.2023.2287490 · Cited by 3 · see citing works
The Continuing Scourge of Atherosclerotic Cardiovascular Disease: Importance of Multidisciplinary and Innovative Person-Centred Approaches
Cheng, A., Krauter, M. B., Mullen, K., & Liu, P. P. (2024) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2024.06.001 · Cited by 3 · see citing works
A Multimodal Patient-Centered Teleprehabilitation Approach for Patients Undergoing Surgery for Breast Cancer: A Clinical Perspective
Mostaqim, K., Lahousse, A., Ubaghs, S., Timmermans, A. A. A., Deliens, T., Vanhoeij, M., Fontaine, C., de Jonge, E., Hoecke, J. V., Polastro, L., et al. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13237393 · Cited by 2 · see citing works
Self-citation
Actively Waiting: Feasibility and Acceptability of a Virtual Self-Management Program Designed to Empower People With Chronic Pain Waiting for Interprofessional Care
Bosma, R. L., Mustafa, N., Burke, E., Alsius, A., Bisson, E. J., Cooper, L., Salomons, T. V., Galica, J., Poulin, P. A., Wiggin, M., et al. (2024) · Pain Management Nursing · doi:10.1016/j.pmn.2024.10.020 · Cited by 2 · see citing works
Evaluating the Impact on Pain Perceptions, Pain Intensity, and Physical Activity of a Mobile App to Empower Employees With Musculoskeletal Pain: Mixed Methods Pilot Study
Keyaerts, S., Szymanski, M., Godderis, L., Abeele, V. V., & Daenen, L. (2025) · JMIR Formative Research · doi:10.2196/67886 · Cited by 2 · see citing works
Healing vs. hurting words: the power of language in pain perception—a narrative review
Leonardi, G., Bonanno, F., Alito, A., Stamile, A., Domenico, C. D., Dio, A. D., Sposito, F., Cucinotta, C., Tisano, A., & Portaro, S. (2026) · Frontiers in Pain Research · doi:10.3389/fpain.2026.1835194 · Cited by 2 · see citing works
Self-Management and Low Back Pain
Diener, I. (2021) · Springer eBooks · doi:10.1007/978-3-030-69736-5_6 · Cited by 2 · see citing works
Empowering patients with persistent pain: The potential of cognitive functional therapy in interdisciplinary care: A single-case experimental design
Zingg, S., de Graaf, M., & Hilfiker, R. (2023) · Journal of Bodywork and Movement Therapies · doi:10.1016/j.jbmt.2023.11.063 · Cited by 2 · see citing works
Effect of perceived injustice-targeted pain neuroscience education compared with biomedically focused education in breast cancer survivors: a study protocol for a multicentre randomised controlled trial (BCS-PI trial)
Roose, E. C. S., Huysmans, E., Leysen, L., Mostaqim, K., van Wilgen, P., Beckwée, D., Couck, M., Timmermans, A. A. A., Bults, R., Nijs, J., et al. (2024) · BMJ Open · doi:10.1136/bmjopen-2023-075779 · Cited by 4 · see citing works
Self-citation
Emergency Department Visit Frequency Among Adults With Chronic Abdominal Pain: Findings From the 2023 US National Health Interview Survey
Ray, B. M., Kelleran, K. J., Kaisler, M. C., & Meltzer, A. C. (2025) · Academic Emergency Medicine · doi:10.1111/acem.70085 · Cited by 3 · see citing works
Introduction to OA, communication, and person-centered care
Østerås, N., & Bunzli, S. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-99269-5.00001-3 · Cited by 2 · see citing works
Effect of motivational interviewing on lifestyle modification among patients with hypertension attending the family medicine clinics of Irrua Specialist Teaching Hospital, Irrua, Nigeria – A randomized controlled trial (MILMAPH Study)Preprint
Oseni, T. I. A., Oku, A. O., Monye, I. N., Ahmed, S. D., Duke, R. E., Otaigbe, O., & Udonwa, N. E. (2024) · medRxiv · doi:10.1101/2024.04.16.24305912 · Cited by 2 · see citing works
Online training improves motivational counseling in health insurance practitioners: a pre-post analysis of return-to-work conversations
Rymenans, I., Lauwerier, E., Bois, M. D., Vanovenberghe, C., & den Broeck, A. V. (2025) · Disability and Rehabilitation · doi:10.1080/09638288.2025.2486460 · Cited by 1 · see citing works
Addressing treatment fatigue, therapeutic inertia, and cognitive dissonance in musculoskeletal pain management in primary care setting
Jerjes, W., Harding, D., & Hilton, A. (2025) · Frontiers in Medicine · doi:10.3389/fmed.2025.1543434 · Cited by 1 · see citing works
Efficacy of Pain Neuroscience Education Combined with Exercise in Older Adults with Chronic Pain: Study Protocol for a Randomized Controlled Trial
Torres-Alonso, J., Polo-Ferrero, L., Hernández-Rubia, S., Sánchez-Sánchez, M. C., Puente-González, A. S., Sáez-Gutiérrez, S., Sánchez, R. M., & Iglesias, F. J. B. (2026) · Journal of Clinical Medicine · doi:10.3390/jcm15103696 · Cited by 1 · see citing works
Pain Resilience Therapy vs. Pain Neuroscience Education for Adults with Chronic Low Back Pain: Secondary Analysis of Data from a Randomized Controlled Trial of Risk and Resilience Factors
Tatta, J., Palombaro, K. M., Bezner, J. R., Pignataro, R. M., & Rothschild, C. (2026) · Healthcare · doi:10.3390/healthcare14131940 · Cited by 1 · see citing works
Knowing isn’t doing: a behavior change perspective on chronic pain management
Bezner, J. R. (2026) · Frontiers in Public Health · doi:10.3389/fpubh.2026.1876192 · Cited by 1 · see citing works
Consultations Preliminary to Interdisciplinary Chronic Pain Rehabilitation
Stinesen, B., Sneijder, P., Köke, A. J. A., & Smeets, R. (2023) · European Journal of Health Communication · doi:10.47368/ejhc.2023.202 · Cited by 1 · see citing works
Self-citation
Efectividad de la entrevista motivacional en la atención fisioterápica de los trastornos musculoesqueléticos de la espalda
González, J. P. F., Espiñeira, M. M. D., & de León, A. C. (2023) · Fisioterapia · doi:10.1016/j.ft.2023.10.003 · Cited by 1 · see citing works
Croyances délétères du patient souffrant de lombalgie chronique : pourquoi s’y intéresser ?
Demoulin, C., Bailly, F., Christe, G., Fourré, A., Salamun, I., & Genevay, S. (2024) · Revue du Rhumatisme · doi:10.1016/j.rhum.2024.03.010 · Cited by 1 · see citing works
Unveiling relevant emotions, cognitions, and behaviours from the viewpoint of people with chronic low back pain: A qualitative study with patient involvement
Matias-Soto, J., Galán, C. P., Martin-Sanchez, A. I., Mesa, J. M. G., Alves, A. A., & Luque-Suárez, A. (2024) · Musculoskeletal Science and Practice · doi:10.1016/j.msksp.2024.103123 · Cited by 1 · see citing works
Analysing and Evaluating Patient–Practitioner Interaction About Chronic Pain: A Workshop for Pain Rehabilitation Practitioners
Stinesen, B., Sneijder, P., Kelder, I., van Dijk, H., Smeets, R., & Köke, A. J. A. (2024) · Palgrave Studies in Discursive Psychology. · doi:10.1007/978-3-031-59551-6_5 · Cited by 1 · see citing works
Self-citation
Design of a Health Education Program to Manage Chronic Neck Pain: Protocol for a Development Study
Pérez-Muñoz, M., Rodríguez‐Costa, I., Lebrijo-Pérez, G., Pecos‐Martín, D., Gallego‐Izquierdo, T., & Pérez-Martín, Y. (2024) · JMIR Research Protocols · doi:10.2196/56632 · Cited by 1 · see citing works
Neuroscience-based approaches in chronic pain management: integration of mind-body interventions in rehabilitation
Kim, H. (2025) · Exploration of Medicine · doi:10.37349/emed.2025.1001282 · Cited by 9 · see citing works
Effectiveness of pain neuroscience education, motivational interviewing and cognition targeted exercise therapy in patients with chronic neck pain: protocol for a multicentre randomised controlled trial (the COGMO-AP study)
Tejera, D. M., Nijs, J., Malfliet, A., Aldana, M. A. P., Vidal, M. I. G., Polentinos-Castro, E., Fernández, M. T. L., & Fernández‐Carnero, J. (2025) · BMJ Open · doi:10.1136/bmjopen-2024-087788 · Cited by 1 · see citing works
Self-citation
Training Rehabilitation Providers in Mental and Behavioral Health: A Pilot Study
Louw, A. (2022) · Annals of Physiotherapy & Occupational Therapy · doi:10.23880/aphot-16000228 · Cited by 1 · see citing works
Self-citation
Psychologically Informed Practice: 3 Low Back Pain Cases
Beneciuk, J. M., Baker, S., Tachibana, B., Vickers, R., Cristello, S., & Davis, A. L. (2021) · JOSPT Cases · doi:10.2519/josptcases.2021.10008 · Cited by 1 · see citing works
فاعلیة برنامج قائم على اسلوب المقابلة التحفیزیة لتحسین الإفصاح الوجدانی والطمأنینة النفسیة فی خفض عدوى الانفعال السلبى لدى عینة من مرضى القلب
محمد, ر. ع., & الباز, ن. ا. (2022) · المجلة المصرية للدراسات النفسية · doi:10.21608/ejcj.2022.212013
Innovative Maßnahmen in der Schmerzphysiotherapie
Schäfer, A. G. M. (2022) · Der Schmerz · doi:10.1007/s00482-022-00631-3
Physiotherapists’ Perspectives on Type 2 Diabetes Management and as a Primary Condition for Referral to Physiotherapy Services: A Qualitative Descriptive Study
Janssen, S. M., Connelly, D. M., & Gillis, H. (2023) · Physiotherapy Canada · doi:10.3138/ptc-2022-0022
Terapia psychoseksualna w ujęciu interdyscyplinarnym. Studium przypadku: pacjentka z zaburzeniami lękowymi i nadmiernym napięciem mięśni dna miednicy
Rawińska, M., & Starzec‐Proserpio, M. (2022) · Przegląd Psychologiczny · doi:10.31648/przegldpsychologiczny.7636
Pain Neuroscience Education Delivered Through Virtual Reality for Common Musculoskeletal Conditions Seen in Physical Therapy: An Exploratory Study
Louw, A., Zimney, K. J., Stopher, D., Saldanha, K. G., Shockley, J., Elliott, L., Macera, D., & Cox, T. (2023) · Reports on Global Health Research · doi:10.29011/2690-9480.100157
Self-citation
Immediate Effects of a Brief 10-Minute Mindfulness-Based Stress Reduction Body Scan for Central Sensitization: A Case Series
Louw, A., McConahay, J., Rico, D., Podolak, J., & Louw, H. (2023) · Journal of Yoga and Physiotherapy · doi:10.19080/jyp.2023.10.555789
Self-citation
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Authors: Nijs, J., Wijma, A. J., Willaert, W., Huysmans, E., Mintken, P., Smeets, R., Goossens, M., van Wilgen, C. P., Van Bogaert, W., Louw, A., Cleland, J., & Donaldson, M.
Affiliations: Vrije Universiteit Brussel (BE)
University of Colorado Boulder (US)
Maastricht University (NL)
Vrije Universiteit Brussel; and Transcare Pain, Transdisciplinary Treatment Center Department of Physiotherapy, Faculty of Physical Education and Physiotherapy, Pain in Motion International Research Group,
Pain in Motion International Research Group, Vrije Universiteit Brussel Department of Physiotherapy, Faculty of Physical Education and Physiotherapy,
International Spine and Pain Institute (US)
Franklin Pierce University (US)
Tufts University (US)
Corresponding author: Nijs, Jo
ORCID: Nijs, Jo
Willaert, Ward
Huysmans, Eva
Mintken, Paul
Smeets, Rob
Goossens, Mariëlle
Louw, Adriaan
Donaldson, Megan
Venue: Physical Therapy
Publisher: Oxford University Press (OUP)
Published: 2020-01-29
Volume: 100
Issue: 5
Pages: 846-859
ISSN: 0031-9023 (ISSN-L)
1538-6724
DOI: 10.1093/ptj/pzaa021
OpenAlex: W3003369303
Cited by: 97
References: 62
Citations by year: 2026: 9 · 2025: 19 · 2024: 22 · 2023: 21 · 2022: 10 · 2021: 12 · 2020: 4
FWCI: 7.05
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
Locations: Physical Therapy (publishedVersion)
PubMed (publishedVersion)
Research Publications (Maastricht University) (acceptedVersion, other-oa)
VUBIR (Vrije Universiteit Brussel) (submittedVersion)
Research Publications (Maastricht University) (submittedVersion, other-oa)
Funders: European College for Lymphatic Therapy, Harderwijk
Research Foundation Flanders (G007217)
Topics: Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
Health Sciences › Medicine › Physiology › Pain Mechanisms and Treatments
Keywords: pain neuroscience education, motivational interviewing, chronic pain, patient education, pain beliefs, pain coping, biopsychosocial model of pain, patient-centered communication, behavior change, medication adherence, quality of life
MeSH terms: Cognition, Humans, Neurosciences, Quality of Life, Practice Guidelines as Topic, Pain Perception, Chronic Pain, Motivational Interviewing

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Integrating Motivational Interviewing in Pain Neuroscience Education for People With Chronic Pain: A Practical Guide for Clinicians

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