The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Effect of annual intramuscular vitamin D on fracture risk in elderly men and women a population-based, randomized, double-blind, placebo-controlled trial
Open accessAbstract
OBJECTIVES: Low trauma fractures in older people incur enormous physical, social and economic costs. Previous research indicates that an annual intramuscular injection of vitamin D may reduce fracture rates in this group. This strategy requires validation in a population setting. METHODS: Randomized, double-blind, placebo-controlled trial of 300,000 IU intramuscular (i.m.) vitamin D2 (ergocalciferol) injection or matching placebo every autumn over 3 years. 9440 people (4354 men and 5086 women) aged 75 yrs and over were recruited from general practice registers in Wessex, England. Primary outcome measure was all non-vertebral fracture. Secondary outcomes were hip and wrist fractures, and all falls. RESULTS: 585 subjects had incident non-spine fractures (hip 110, wrist 116, ankle 37). Hazard ratios (HRs) for fracture in the vitamin D group were: 1.09 [95% confidence interval (CI) 0.93-1.28, P = 0.29] for any first fracture, 1.49 (95% CI 1.02-2.18, P = 0.04) for hip and 1.22 (95% CI 0.85-1.76, P = 0.28) for wrist. There was no effect on falls: HR 0.98 (0.93-1.04). No protective effect was observed in any subgroup when the cohort was stratified by sex, age, previous fracture or mobility. CONCLUSIONS: An annual i.m. injection of 300,000 IU vitamin D2 is not effective in preventing non-vertebral fractures among elderly men and women resident in the general population.
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(2005) · The Lancet · doi:10.1016/s0140-6736(05)63013-9 · Cited by 970
Self-citationAvenell, A., Gillespie, W. J., Gillespie, L. D., & O'Connell, D. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000227.pub3 · Cited by 667
Avenell, A., Gillespie, W. J., Gillespie, L. D., & O'Connell, D. (2005) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000227.pub2 · Cited by 165
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European guidance for the diagnosis and management of osteoporosis in postmenopausal women
on behalf of the Scientific Advisory Board of the European Society for Clinical and Economic Aspects of Osteoporosis (ESCEO) and the Committees of Scientific Advisors and National Societies of the International Osteoporosis Foundation (IOF), Kanis, J. A., Cooper, C., Rizzoli, R., & Reginster, J.-Y. (2019) · Osteoporosis International · doi:10.1007/s00198-018-4704-5 · Cited by 1,900
Self-citationQaseem, A., Forciea, M. A., McLean, R. M., Denberg, T. D., & for the Clinical Guidelines Committee of the American College of Physicians* (2017) · Annals of Internal Medicine · doi:10.7326/m15-1361 · Cited by 676
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Bjelakovic, G., Gluud, L. L., Nikolova, D., Whitfield, K., Wetterslev, J., Simonetti, R. G., Bjelakovic, M., & Gluud, C. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007470.pub3 · Cited by 695
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Vitamin D for the prevention of disease: An Endocrine Society clinical practice guideline
Demay, M. B., Pittas, A. G., Bikle, D. D., Diab, D. L., Kiely, M. E., Lazaretti-Castro, M., Lips, P., Mitchell, D. M., Murad, M. H., Powers, S., et al. (2024) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgae290 · Cited by 639
The roles of vitamin D in skeletal muscle: form, function, and metabolism
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The health effects of vitamin D supplementation: Evidence from human studies
Bouillon, R., Manousaki, D., Rosen, C., Trajanoska, K., Rivadeneira, F., & Richards, J. B. (2022) · Nature Reviews Endocrinology · doi:10.1038/s41574-021-00593-z · Cited by 535
Amrein, K., Schnedl, C., Holl, A., Riedl, R., Christopher, K. B., Pachler, C., Urbanic Purkart, T., Waltensdorfer, A., Münch, A., Warnkross, H., et al. (2014) · JAMA · doi:10.1001/jama.2014.13204 · Cited by 493
Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
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Consensus statement on vitamin D status assessment and supplementation: Whys, whens, and hows
Giustina, A., Bilezikian, J. P., Adler, R. A., Banfi, G., Bikle, D. D., Binkley, N. C., Bollerslev, J., Bouillon, R., Brandi, M. L., Casanueva, F. F., et al. (2024) · Endocrine Reviews · doi:10.1210/endrev/bnae009 · Cited by 392
Vitamin D testing and treatment: a narrative review of current evidence
Pilz, S., Zittermann, A., Trummer, C., Theiler-Schwetz, V., Lerchbaum, E., Keppel, M. H., Grübler, M. R., März, W., & Pandis, M. (2019) · Endocrine Connections · doi:10.1530/ec-18-0432 · Cited by 276
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Altieri, B., Grant, W. B., Della Casa, S., Orio, F., Pontecorvi, A., Colao, A., Sarno, G., & Muscogiuri, G. (2017) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2015.1136922 · Cited by 113
Differences in Overlapping Meta-Analyses of Vitamin D Supplements and Falls
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Metadata
- Authors
- Smith, H., Anderson, F., Raphael, H., Maslin, P., Crozier, S., & Cooper, C.
- Venue
- Rheumatology
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-08-05
- Volume
- 46
- Issue
- 12
- Pages
- 1852-1857
- ISSN
- 1462-0324 (ISSN-L)
- 1462-0332
- OpenAlex
- W2147385250
- Cited by
- 400
- References
- 3
- FWCI
- 8.70
- Type
- journal article
- Language
- en
- Open access
- bronze
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