Schizotypy from a developmental perspective
Open accessAbstract
The schizotypy construct focuses attention on the liability to develop schizophrenia-spectrum disorders, yet traditionally, the schizotypy models have put more emphasis on stress-vulnerability interactions rather than developmental dynamics of emerging risk for psychopathology. Indeed, developmental accounts of this emerging personality trait have rarely been explicitly formulated. In this position article, we wish to convey some of the basic developmental tenets of schizotypy, and how they can inform high-risk research. Firstly, we tackle the state vs trait issue to outline the possible relationship between high-risk states and trait schizotypy. Second, we review the evidence suggesting that the consolidation of schizotypy, encompassing its 3 main dimensions, could be considered as a developmental mediator between very early risk factors and transition into high-risk states. Importantly, developmental dynamics between endophenotypes, as well as transactional and epigenetics mechanisms should enter modern conceptualizations of schizotypy. Finally, we present a developmental psychopathology perspective of schizotypy sensitive to both the multifinality and equifinality of schizophrenia-spectrum disorders. We conclude that schizotypy represents a crucial construct in a fully-developmental study of schizophrenia-spectrum disorders.
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Narrative self-disturbances likely follow the same developmental pattern as other psychotic symptoms, beginning in earlier or milder forms of psychosis before becoming severe enough for clinical attention in SSD.
“Research findings in these populations can therefore shed light on the developmental trajectory of narrative self-disturbances, which likely follow the same pattern as other psychotic symptoms, originating in earlier or milder forms of psychosis before becoming severe enough to warrant clinical attention in SSD (Barrantes-Vidal et al., 2015; Debbané & Barrantes-Vidal, 2015).”
From Narrative identity in the psychosis spectrum: A systematic review and developmental model (2021) · cites this paper as Debbané & Barrantes-Vidal, 2015
The Conclusion describes a developmental pathway in which schizotypy can confer liability to psychotic states and may ultimately lead to schizophrenia-spectrum disorders. The Introduction also links adolescent schizotypal symptoms to later help-seeking. Neither passage establishes that narrative self-disturbances specifically follow this trajectory; applying the general model to them is the citing authors’ inference. (LLM, conf=0.85)
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Autistic-Like Traits and Positive Schizotypy as Diametric Specializations of the Predictive Mind
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Enhancing Psychosis-Spectrum Nosology Through an International Data Sharing Initiative
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Normative data of the Magical Ideation Scale from childhood to adulthood in an Italian cohort
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Schizotypy and mental health in women and men from the general population
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Neuropsychology and Neurobiology of Negative Schizotypy: A Selective Review
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Association of subclinical psychosis with suicidal ideation: A twin study
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Cumulative Environmental Risk in Early Life: Associations With Schizotypy in Childhood
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Schizotypy, schizotypal personality, and psychosis risk
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Self-citationLatent mechanisms of language disorganization relate to specific dimensions of psychopathology
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Extending schizophrenia diagnostic model to predict schizotypy in first-degree relatives
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Childhood Schizotypy and Adolescent Mental Disorder
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Self-citationPathogenic beliefs among patients with schizotypal personality disorder
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Chen, S.-N., Zhu, G., Yang, J., Hu, W., Meng, X., Zhang, L., Wang, Y., & Wang, Y.-Y. (2025) · Schizophrenia Research · doi:10.1016/j.schres.2025.01.016 · Cited by 5 · see citing works
Schizotypy, Psychosis Proneness, and the Polygenic Risk for Schizophrenia and Resilience
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Exploring electrophysiological correlates of social cognition in subclinical schizotypy
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Pathways from developmental vulnerabilities in early childhood to schizotypy in middle childhood
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Clinical Evaluation and Intervention of Emerging Psychosis: A Mentalization-Informed Perspective
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Early life factors of schizotypal personality disorder in adolescents: A systematic review
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The effect of schizotypy on spatial learning in an environment with a distinctive shape
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Personality and the Expression of Symptomatology in Schizophrenia and Bipolar Disorder
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Is schizotypic maternal personality linked to sensory gating abilities during infancy?
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Kirschner, M., Hodzic-Santor, B. H., Antoniades, M., Nenadić, I., Kircher, T. T. J., Krug, A., Meller, T., Grotegerd, D., Fornito, A., Arnatkevičiūtė, A., et al. (2021) · medRxiv · doi:10.1101/2021.04.29.21255609 · Cited by 2 · see citing works
Exploring Patterns of Eccentricity: Insights from Network Analysis of Schizotypy in Students
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- Authors
- Debbane, M., & Barrantes-Vidal, N.
- Venue
- Schizophrenia Bulletin
- Publisher
- Oxford University Press (OUP)
- Published
- 2014-12-29
- Volume
- 41
- Issue
- suppl 2
- Pages
- S386-S395
- ISSN
- 0586-7614 (ISSN-L)
- 1745-1701
- PMC
- PMC4373627
- OpenAlex
- W1995998194
- Cited by
- 133
- References
- 54
- Citations by year
- 2026: 4 · 2025: 8 · 2024: 12 · 2023: 13 · 2022: 16 · 2021: 15 · 2020: 14 · 2019: 9 · 2018: 14 · 2017: 11 · 2016: 11 · 2015: 6
- FWCI
- 1.29
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Schizophrenia Bulletin (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Archive ouverte UNIGE (University of Geneva) (submittedVersion, other-oa)
- Funders
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (100014, 135311)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
- Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
- Keywords
- schizotypy, developmental psychopathology
- MeSH terms
- Disease Susceptibility, Humans, Personality Development, Schizotypal Personality Disorder, Disease Progression, Endophenotypes
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