The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
A CLOCK Polymorphism Associated with Human Diurnal Preference
Open accessAbstract
A single nucleotide polymorphism located in the 3' flanking region of the human CLOCK gene was investigated as a predictor of diurnal preference in a population-based random sample of 410 normal adults. Morningness-eveningness preferences were determined using the 19-item Home-Ostberg questionnaire. Subjects carrying one of the two CLOCK alleles, 3111C, had a significantly lower mean Horne-Ostberg score. The distribution of scores was clearly shifted toward eveningness for these subjects. The score difference was independent of age, sex and ethnic heritage, thus making population stratification effects unlikely to explain this difference. These subjects had a substantial 10- to 44-minute delay in preferred timing for activity or sleep episodes. We suggest that the identified polymorphism or another tightly linked polymorphism within the CLOCK gene or its regulatory elements may be responsible for the finding.
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Cites
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Self-citationThe Aryl Hydrocarbon Receptor Complex
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A Differential Response of Two Putative Mammalian Circadian Regulators, mper1and mper2, to Light
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Cited by
Life between Clocks: Daily Temporal Patterns of Human Chronotypes
Roenneberg, T., Wirz-Justice, A., & Merrow, M. (2003) · Journal of Biological Rhythms · doi:10.1177/0748730402239679 · Cited by 2,662
The genetics of mammalian circadian order and disorder: implications for physiology and disease
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Self-citationEpidemiology of the human circadian clock
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Circadian typology: a comprehensive review
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Metadata
- Authors
- Katzenberg, D., Young, T., Finn, L., Lin, L., King, D. P., Takahashi, J. S., & Mignot, E.
- Venue
- Sleep
- Publisher
- Oxford University Press (OUP)
- Published
- 1998-09
- Volume
- 21
- Issue
- 6
- Pages
- 569-576
- ISSN
- 0161-8105 (ISSN-L)
- 1550-9109
- OpenAlex
- W88657933
- Cited by
- 591
- References
- 6
- FWCI
- 4.13
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Katzenberg, D., Young, T., Finn, L., Lin, L., King, D. P., Takahashi, J. S., & Mignot, E. (1998). A CLOCK Polymorphism Associated with Human Diurnal Preference. Sleep. https://doi.org/10.1093/sleep/21.6.569
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
