Early CPAP Use Identifies Subsequent Adherence to CPAP Therapy
Abstract
Study objectives To explore the relationship between specific factors such as sex and early continuous positive airway pressure (CPAP) use, and 30-day adherence to CPAP therapy. Design and setting Retrospective study conducted at a single center in southeast Michigan. Patients One hundred patients with obstructive sleep apnea who were recently initiated on CPAP therapy with electronic adherence information relayed from the CPAP device to a laboratory-based computer through telephone modem. Interventions N/A. Measurements and results An empiric threshold value of objective CPAP use of greater than 4 hours per night measured 3 days following CPAP initiation was predictive of level of CPAP adherence measured 30 days later. Furthermore, CPAP adherence was directly proportional to age (R = 0.25, P = .018). There were no sex-related differences in adherence to CPAP therapy. Conclusions Long-term adherence to CPAP therapy can be predicted as early as 3 days following CPAP initiation. The study also demonstrates that younger age and African-American race are independently associated with lower CPAP adherence.
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CPAP adherence is influenced by race, with reduced adherence reported in Black, Hispanic, and Asian Pacific Islander users compared to white users.
“CPAP adherence is also influenced by race, with reduced adherence reported in Black, Hispanic, and Asian Pacific Islander users compared to white users.1108–1112”
From International Consensus Statement on Obstructive Sleep Apnea (2023) · cites this paper as [1111]
Decisions about PAP usage are made very early after treatment initiation.
“Similar data suggest that decisions about PAP usage are made very early after treatment initiation suggesting any such intervention needs to be delivered early to maximize effect.27”
Cites
Long-term Use of CPAP Therapy for Sleep Apnea/Hypopnea Syndrome
McARDLE, N., DEVEREUX, G., HEIDARNEJAD, H., ENGLEMAN, H. M., MACKAY, T. W., & DOUGLAS, N. J. (1999) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.159.4.9807111 · Cited by 820 · see citing works
Massie, C. A., Hart, R. W., Peralez, K., & Richards, G. N. (1999) · Chest · doi:10.1378/chest.116.2.403 · Cited by 308 · see citing works
Compliance With Nasal CPAP Can Be Improved by Simple Interventions
Chervin, R. D., Theut, S., Bassetti, C., & Aldrich, M. S. (1997) · Sleep · doi:10.1093/sleep/20.4.284 · Cited by 242 · see citing works
The relationship between chronically disrupted sleep and healthcare use
(2002) · Sleep · doi:10.1093/sleep/25.3.289 · Cited by 169 · see citing works
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Cited by
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Adherence to Continuous Positive Airway Pressure Therapy: The Challenge to Effective Treatment
Weaver, T. E., & Grunstein, R. R. (2008) · Proceedings of the American Thoracic Society · doi:10.1513/pats.200708-119mg · Cited by 1,680 · see citing works
Sawyer, A. M., Gooneratne, N. S., Marcus, C. L., Ofer, D., Richards, K. C., & Weaver, T. E. (2011) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2011.01.003 · Cited by 900 · see citing works
Patil, S. P., Ayappa, I. A., Caples, S. M., Kimoff, R. J., Patel, S. R., & Harrod, C. G. (2019) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.7640 · Cited by 881 · see citing works
Patil, S. P., Ayappa, I. A., Caples, S. M., Kimoff, R. J., Patel, S. R., & Harrod, C. G. (2019) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.7638 · Cited by 721 · see citing works
Sleep as a Potential Fundamental Contributor to Disparities in Cardiovascular Health
Jackson, C. L., Redline, S., & Emmons, K. M. (2015) · Annual Review of Public Health · doi:10.1146/annurev-publhealth-031914-122838 · Cited by 388 · see citing works
International Consensus Statement on Obstructive Sleep Apnea
Chang, J. L., Goldberg, A. N., Alt, J. A., Mohammed, A., Ashbrook, L., Auckley, D., Ayappa, I., Bakhtiar, H., Barrera, J. E., Bartley, B. L., et al. (2023) · International Forum of Allergy & Rhinology · doi:10.1002/alr.23079 · Cited by 350 · see citing works
Obstructive sleep apnea and orthodontics: An American Association of Orthodontists White Paper
Behrents, R. G., Shelgikar, A. V., Conley, R. S., Flores-Mir, C., Hans, M., Levine, M., McNamara, J. A., Palomo, J. M., Pliska, B., Stockstill, J. W., et al. (2019) · American Journal of Orthodontics and Dentofacial Orthopedics · doi:10.1016/j.ajodo.2019.04.009 · Cited by 284 · see citing works
Predictors of Continuous Positive Airway Pressure Adherence in Patients with Obstructive Sleep Apnea
Mehrtash, M., Bakker, J. P., & Ayas, N. (2019) · Lung · doi:10.1007/s00408-018-00193-1 · Cited by 231 · see citing works
Race and Residential Socioeconomics as Predictors of CPAP Adherence
Billings, M. E., Auckley, D., Benca, R., Foldvary-Schaefer, N., Iber, C., Redline, S., Rosen, C. L., Zee, P., & Kapur, V. K. (2011) · Sleep · doi:10.5665/sleep.1428 · Cited by 190 · see citing works
Post-approval upper airway stimulation predictors of treatment effectiveness in the ADHERE registry
Heiser, C., Steffen, A., Boon, M., Hofauer, B., Doghramji, K., Maurer, J. T., Sommer, J. U., Soose, R., Strollo, P. J., Schwab, R., et al. (2019) · European Respiratory Journal · doi:10.1183/13993003.01405-2018 · Cited by 158 · see citing works
Neighborhood of Residence is Associated with Daily Adherence to CPAP Therapy
Platt, A. B., Field, S. H., Asch, D. A., Chen, Z., Patel, N. P., Gupta, R., Roche, D. F., Gurubhagavatula, I., Christie, J. D., & Kuna, S. T. (2009) · Sleep · doi:10.1093/sleep/32.6.799 · Cited by 128 · see citing works
Age and Sex Disparities in Adherence to CPAP
Patel, S. R., Bakker, J. P., Stitt, C. J., Aloia, M. S., & Nouraie, S. M. (2021) · Chest · doi:10.1016/j.chest.2020.07.017 · Cited by 122 · see citing works
Van Ryswyk, E., Anderson, C. S., Antic, N. A., Barbe, F., Bittencourt, L., Freed, R., Heeley, E., Liu, Z., Loffler, K. A., Lorenzi-Filho, G., et al. (2019) · Sleep · doi:10.1093/sleep/zsz152 · Cited by 115 · see citing works
Correlates of Pediatric CPAP Adherence
Hawkins, S. M. M., Jensen, E. L., Simon, S. L., & Friedman, N. R. (2016) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.5892 · Cited by 102 · see citing works
Kuna, S. T., Shuttleworth, D., Chi, L., Schutte-Rodin, S., Friedman, E., Guo, H., Dhand, S., Yang, L., Zhu, J., Bellamy, S. L., et al. (2015) · Sleep · doi:10.5665/sleep.4898 · Cited by 97 · see citing works
Bakker, J. P., O'Keeffe, K. M., Neill, A. M., & Campbell, A. J. (2011) · Sleep · doi:10.5665/sleep.1404 · Cited by 93 · see citing works
The Efficacy of a Brief Motivational Enhancement Education Program on CPAP Adherence in OSA
Lai, A. Y. K., Fong, D. Y. T., Lam, J. C. M., Weaver, T. E., & Ip, M. S. M. (2014) · Chest · doi:10.1378/chest.13-2228 · Cited by 89 · see citing works
Nasal inflammation in sleep apnoea patients using CPAP and effect of heated humidification
Koutsourelakis, I., Vagiakis, E., Perraki, E., Karatza, M., Magkou, C., Kopaka, M., Roussos, C., & Zakynthinos, S. (2011) · European Respiratory Journal · doi:10.1183/09031936.00036910 · Cited by 72 · see citing works
Nguyên, X.-L., Chaskalovic, J., Rakotonanahary, D., & Fleury, B. (2010) · Sleep Medicine · doi:10.1016/j.sleep.2010.04.008 · Cited by 69 · see citing works
Auto-adjusting Positive Airway Pressure Treatment for Sleep Apnea Diagnosed by Home Sleep Testing
Berry, R. B., & Sriram, P. (2014) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.4272 · Cited by 64 · see citing works
Deshpande, S., Joosten, S., Turton, A., Edwards, B. A., Landry, S., Mansfield, D. R., & Hamilton, G. S. (2016) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.6128 · Cited by 61 · see citing works
Wallace, D. M., Vargas, S. S., Schwartz, S. J., Aloia, M. S., & Shafazand, S. (2013) · Sleep and Breathing · doi:10.1007/s11325-012-0702-6 · Cited by 59 · see citing works
Nasal function and CPAP compliance
Inoue, A., Chiba, S., Matsuura, K., Osafune, H., Capasso, R., & Wada, K. (2019) · Auris Nasus Larynx · doi:10.1016/j.anl.2018.11.006 · Cited by 57 · see citing works
A Pilot Study Assessing Adherence to Auto-Bilevel Following a Poor Initial Encounter with CPAP
Powell, E. D., Gay, P. C., Ojile, J. M., Litinski, M., & Malhotra, A. (2012) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.1658 · Cited by 46 · see citing works
Guralnick, A. S., Balachandran, J. S., Szutenbach, S., Adley, K., Emami, L., Mohammadi, M., Farnan, J. M., Arora, V. M., & Mokhlesi, B. (2017) · Thorax · doi:10.1136/thoraxjnl-2017-210106 · Cited by 36 · see citing works
Assessment of the Performance of Nasal Pillows at High CPAP Pressures
Zhu, X., Wimms, A. J., & Benjafield, A. V. (2013) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.2984 · Cited by 27 · see citing works
Racial disparity in adherence to positive airway pressure among US veterans
Schwartz, S. W., Sebastião, Y., Rosas, J., Iannacone, M. R., Foulis, P. R., & Anderson, W. M. (2016) · Sleep and Breathing · doi:10.1007/s11325-016-1316-1 · Cited by 24 · see citing works
Saraç, S., Afşar, G. Ç., Oruç, Ö., Topçuoğlu, Ö. B., Saltürk, C., & Peker, Y. (2017) · Medical Science Monitor · doi:10.12659/msm.902075 · Cited by 22 · see citing works
Westlake, K., Dostalova, V., Plihalova, A., Pretl, M., & Polak, J. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00714 · Cited by 11 · see citing works
Nilius, G., Cottin, U., Domanski, U., van’t Hoog, T., Franke, K.-J., Burian, S., & Ruehle, K.-H. (2012) · Somnologie - Schlafforschung und Schlafmedizin · doi:10.1007/s11818-012-0580-y · Cited by 10 · see citing works
Lipid profile after long-term APAP in OSA patients
Rebelo, S., Drummond, M., & Marques, J. A. (2015) · Sleep And Breathing · doi:10.1007/s11325-014-1095-5 · Cited by 6 · see citing works
Lettieri, C. J., Shah, A. A., Holley, A. B., Kelly, W. F., Chang, A. S., Roop, S. A., & Trial, F. T. C. A. (. P. A. P. A. S. A. P. (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-151-10-200911170-00006 · Cited by 2 · see citing works
- Authors
- Budhiraja, R., Parthasarathy, S., Drake, C. L., Roth, T. G., Sharief, I., Budhiraja, P., Saunders, V., & Hudgel, D. W.
- Affiliations
- University of Arizona (US)
- Henry Ford Hospital (US)
- Corresponding author
- Rohit Budhiraja
- ORCID
- Venue
- Sleep
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-03-01
- Volume
- 30
- Issue
- 3
- Pages
- 320-4
- ISSN
- 0161-8105 (ISSN-L)
- 1550-9109
- OpenAlex
- W177216907
- Cited by
- 329
- References
- 4
- Citations by year
- 2026: 2 · 2025: 8 · 2024: 11 · 2023: 14 · 2022: 20 · 2021: 21 · 2020: 21 · 2019: 24 · 2018: 19 · 2017: 19 · 2016: 21 · 2015: 18 · 2014: 24 · 2013: 23 · 2012: 21
- FWCI
- 9.43
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- SLEEP (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Keywords
- CPAP adherence, continuous positive airway pressure, obstructive sleep apnea, electronic adherence monitoring, age and adherence, sex differences, African American race, adherence prediction
- MeSH terms
- Adult, Age Factors, Aged, Aged, 80 and over, Female, Humans, Long-Term Care, Male, Middle Aged, Patient Compliance, Retrospective Studies, Telemetry, Sleep Apnea, Obstructive, Continuous Positive Airway Pressure
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