Targeting multiple Alzheimer's disease etiologies with multimodal neuroprotective and neurorestorative iron chelators

Dysregulation of brain iron homeostasis is central to early neuropathological events in Alzhei mer's disease (AD), including oxidative stress, inflam matory processes, amyloid deposition, tau phosphory lation, and neuronal cell cycle regulatory failure, leading to apoptosis. Also, there is a dire…