The Preferred Option for Multinodular Goiter
Open accessAbstract
Total thyroidectomy is an operation that has generally been reserved for the management of differentiated thyroid carcinoma. Over the last decade total thyroidectomy has become used increasingly and is now the preferred option in the authors' unit for the management of multinodular goiter affecting the entire gland. Over the period from 1975 to 1985, 853 thyroidectomies have been performed for multinodular goiter; of these, 115 have been total thyroidectomies. During that time, the incidence of total thyroidectomy for multinodular goiter has increased in percentage terms from 9% in 1975 to 50% in 1985. There have been two cases of permanent hypoparathyroidism and one case of permanent recurrent laryngeal nerve injury, and these occurred in patients who had less than total thyroidectomy. Total thyroidectomy is an appropriate operation for the management of diffuse multinodular goiter where the entire gland is involved because it precludes patients from requiring further surgery for recurrent disease, with its high associated risks. It must be emphasized, however, that protection of the recurrent laryngeal nerve and parathyroid glands must still be paramount in dealing with benign thyroid disease.
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Near-total or total thyroidectomy can be performed with the same low rate of complications as subtotal thyroidectomy.
“This procedure can be performed with the same low rate of complications as a subtotal thyroidectomy (286-289).”
From 2016 American Thyroid Association Guidelines for Diagnosis and Management of Hyperthyroidism and Other Causes of Thyrotoxicosis (2016) · cites this paper as [286]
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- Authors
- REEVE, T. S., DELBRIDGE, L., COHEN, A., & CRUMMER, P.
- Affiliations
- The University of Sydney (AU)
- ORCID
- DELBRIDGE, L.
- Venue
- Annals of Surgery
- Published
- 1987-12
- Volume
- 206
- Issue
- 6
- Pages
- 782-786
- ISSN
- 0003-4932 (ISSN-L)
- PMC
- PMC1493314
- OpenAlex
- W1591468959
- Cited by
- 214
- References
- 8
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 3 · 2022: 4 · 2021: 1 · 2020: 5 · 2019: 4 · 2018: 3 · 2017: 7 · 2016: 6 · 2015: 3 · 2014: 6 · 2013: 7 · 2012: 9
- FWCI
- 2.92
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Annals of Surgery (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Thyroid and Parathyroid Surgery
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Cancer Diagnosis and Treatment
- Keywords
- multinodular goiter, total thyroidectomy, thyroidectomy, recurrent laryngeal nerve injury, hypoparathyroidism, parathyroid preservation, benign thyroid disease, surgical outcomes
- MeSH terms
- Goiter, Nodular, Humans, Hypoparathyroidism, Thyroidectomy, Vocal Cord Paralysis, Recurrent Laryngeal Nerve Injuries
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