The DOI matches its Crossref record.
Correlation between periinfarct DC shifts and ischaemic neuronal damage in rat
Abstract
The effect of peri-infarct depolarizations on ischaemic injury was studied in rats submitted to 3 h occlusion of the left middle cerebral artery (MCA). The number of depolarizations varied from 1 to 8 and infarct volume from 37 to 159 mm3. The correlation between the two variables revealed a highly significant linear relationship (r = 0.800; p < 0.005), each depolarization accounting for an increase in infarct volume by about 13 mm3. The aggravating effect of repeated depolarizations was also demonstrated by the gradual increase in cortical DC shift duration, in EEG amplitude recovery time, and in EEG delta power with increasing number of depolarizations. Suppression of peri-infarct depolarizations is a rational approach for reducing the severity of ischaemic stroke.
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Citations
Cited by
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New roles for astrocytes: redefining the functional architecture of the brain.
Nedergaard, M., Ransom, B., & Goldman, S. A. (2003) · Trends in Neurosciences · doi:10.1016/j.tins.2003.08.008 · Cited by 1,334
Dreier, J. P. (2011) · Nature Medicine · doi:10.1038/nm.2333 · Cited by 1,132
Lauritzen, M., Dreier, J. P., Fabricius, M., Hartings, J. A., Graf, R., & Strong, A. J. (2011) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2010.191 · Cited by 782
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Hossmann, K.-A. (2006) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-006-9008-1 · Cited by 475
Self-citationFabricius, M., Fuhr, S., Bhatia, R., Boutelle, M., Hashemi, P., Strong, A. J., & Lauritzen, M. (2006) · Brain · doi:10.1093/brain/awh716 · Cited by 420
Dreier, J. P., Fabricius, M., Ayata, C., Sakowitz, O. W., William Shuttleworth, C., Dohmen, C., Graf, R., Vajkoczy, P., Helbok, R., Suzuki, M., et al. (2017) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x16654496 · Cited by 350
Spreading depolarizations cycle around and enlarge focal ischaemic brain lesions
Nakamura, H., Strong, A. J., Dohmen, C., Sakowitz, O. W., Vollmar, S., Sué, M., Kracht, L., Hashemi, P., Bhatia, R., Yoshimine, T., et al. (2010) · Brain · doi:10.1093/brain/awq117 · Cited by 212
Risher, W. C., Ard, D., Yuan, J., & Kirov, S. A. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.1917-10.2010 · Cited by 153
Feuerstein, D., Manning, A., Hashemi, P., Bhatia, R., Fabricius, M., Tolias, C., Pahl, C., Ervine, M., Strong, A. J., & Boutelle, M. G. (2010) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2010.17 · Cited by 127
Hashemi, P., Bhatia, R., Nakamura, H., Dreier, J. P., Graf, R., Strong, A. J., & Boutelle, M. G. (2009) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2008.108 · Cited by 101
Dreier, J. P., Isele, T., Reiffurth, C., Offenhauser, N., Kirov, S. A., Dahlem, M. A., & Herreras, O. (2013) · The Neuroscientist · doi:10.1177/1073858412453340 · Cited by 94
von Baumgarten, L., Trabold, R., Thal, S., Back, T., & Plesnila, N. (2008) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2008.30 · Cited by 53
Metadata
- Authors
- Mies, G., lijima, T., & Hossmann, K.-A.
- Venue
- NeuroReport
- Published
- 1993-06
- Volume
- 4
- Issue
- 6
- Pages
- 709-711
- ISSN
- 0959-4965 (ISSN-L)
- OpenAlex
- W2077484357
- Cited by
- 404
- References
- 0
- FWCI
- 7.80
- Type
- journal article
- Language
- en
- Open access
- closed
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