Minocycline and Other Tetracycline Derivatives: A Neuroprotective Strategy in Parkinson’s Disease and Huntington’s Disease
Abstract
Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, Texas, USA Address correspondence and reprint requests to Dr. Joseph Jankovic, Director, Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, 6550 Fannin St. #1801, Houston, TX 77030, USA; E-mail: [email protected]
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Minocycline efficiently crosses the BBB.
“Thanks to the ability to efficiently cross the BBB, minocycline is considered neuroprotective for a variety of neurological conditions, including PD [251,252,253,254,255,256,257].”
From The Interplay between Gut Microbiota and Parkinson’s Disease: Implications on Diagnosis and Treatment (2022) · cites this paper as [252]
Minocycline is considered neuroprotective for a variety of neurological conditions, including PD.
“Thanks to the ability to efficiently cross the BBB, minocycline is considered neuroprotective for a variety of neurological conditions, including PD [251,252,253,254,255,256,257].”
From The Interplay between Gut Microbiota and Parkinson’s Disease: Implications on Diagnosis and Treatment (2022) · cites this paper as [252]
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- Authors
- Thomas, M., Le, W. D., & Jankovic, J.
- Affiliations
- Baylor College of Medicine (US)
- Corresponding author
- Jankovic, Joseph
- ORCID
- Jankovic, Joseph
- Venue
- Clinical Neuropharmacology
- Published
- 2003-01
- Volume
- 26
- Issue
- 1
- Pages
- 18-23
- ISSN
- 0362-5664 (ISSN-L)
- OpenAlex
- W2012475537
- Cited by
- 62
- References
- 60
- Citations by year
- 2025: 4 · 2023: 2 · 2022: 3 · 2021: 1 · 2020: 1 · 2019: 1 · 2018: 1 · 2013: 2 · 2012: 4
- FWCI
- 1.32
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Neuropharmacology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Keywords
- minocycline, tetracycline derivatives, neuroprotection, Parkinson's disease, Huntington's disease, neurodegeneration
- MeSH terms
- Animals, Brain, Humans, Huntington Disease, Minocycline, Parkinson Disease, Tetracyclines, Neuroprotective Agents
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