Cited by 519Parkinson's Disease Mechanisms and TreatmentsUbiquitin and proteasome pathwaysAutophagy in Disease and Therapy

Failure of the ubiquitin-proteasome system in Parkinson’s disease

McNaught, Kevin St P., Olanow, C. Warren, Halliwell, Barry, Isacson, Ole, Jenner, Peter·2001·Nature Reviews Neuroscience

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Crossref · 10.1038/35086067

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66 of 66 references verified0 citation errors · 0 not checkable

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Authors
McNaught, K. S. P., Olanow, C. W., Halliwell, B., Isacson, O., & Jenner, P.
Affiliations
  • Harvard University (US)
  • Icahn School of Medicine at Mount Sinai (US)
  • National University of Singapore (SG)
  • King's College London (GB)
Venue
Nature Reviews Neuroscience
Published
2001-08
Volume
2
Issue
8
Pages
589-594
ISSN
  • 1471-003X (ISSN-L)
  • 1471-0048
OpenAlex
W2067340670
Cited by
519
References
66
Citations by year
2026: 5 · 2025: 12 · 2024: 6 · 2023: 17 · 2022: 15 · 2021: 20 · 2020: 16 · 2019: 17 · 2018: 8 · 2017: 20 · 2016: 9 · 2015: 16 · 2014: 13 · 2013: 18 · 2012: 18
FWCI
6.48
Type
journal article
Language
en
Open access
closed
Locations
  • Nature reviews. Neuroscience (publishedVersion)
  • PubMed (publishedVersion)
  • National University of Singapore (submittedVersion)
  • Research Portal (King's College London) (submittedVersion)
Topics
  • Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Ubiquitin and proteasome pathways
  • Health Sciences › Medicine › Epidemiology › Autophagy in Disease and Therapy
Keywords
Parkinson's disease, ubiquitin-proteasome system, neurodegeneration, dopaminergic neurons, familial Parkinson's disease, sporadic Parkinson's disease, protein degradation, genetic mutations
MeSH terms
Animals, Cysteine Endopeptidases, Humans, Multienzyme Complexes, Nerve Tissue Proteins, Parkinson Disease, Peptide Hydrolases, Substantia Nigra, Ubiquitins, Lewy Bodies, Proteasome Endopeptidase Complex

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