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Childhood and adolescent depression: a review of the past 10 years, Part I
Abstract
Objective To qualitatively review the literature of the past decade covering the epidemiology, clinical characteristics, natural course, biology, and other correlates of early-onset major depressive disorder (MDD) and dysthymic disorder (DD).Method A computerized search for articles published during the past 10 years was made and selected studies are presented.Results Early-onset MDD and DD are frequent, recurrent, and familial disorders that tend to continue into adulthood, and they are frequently accompanied by other psychiatric disorders. These disorders are usually associated with poor psychosocial and academic outcome and increased risk for substance abuse, bipolar disorder, and suicide. In addition, DD increases the risk for MDD. There is a secular increase in the prevalence of MDD, and it appears that MDD is occurring at an earlier age in successive cohorts. Several genetic, familial, demographic, psychosocial, cognitive, and biological correlates of onset and course of early-onset depression have been identified. Few studies, however, have examined the combined effects of these correlates.Conclusions Considerable advances have been made in our knowledge of early-onset depression. Nevertheless, further research is needed in understanding the pathogenesis of childhood mood disorders. Toward this end, studies aimed at elucidating mechanisms and interrelationships among the different domains of risk factors are needed.
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“Major depressive disorder, however, is too uncommon in childhood to be useful as a predictor of later disorder.”
From Subthreshold Symptoms of Depression in Preadolescent Girls Are Stable and Predictive of Depressive Disorders (2008) · cites this paper as [1]
In the citing paper
“These rates are higher than those reported in population-based samples of children,1 reflecting the success of the screening to increase the base rate of depressive disorders.”
From Subthreshold Symptoms of Depression in Preadolescent Girls Are Stable and Predictive of Depressive Disorders (2008) · cites this paper as [1]
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Occult Depressive Symptoms in Adolescent Emergency Department Patients
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Metadata
- Authors
- BIRMAHER, B., RYAN, N. D., WILLIAMSON, D. E., BRENT, D. A., KAUFMAN, J., DAHL, R. E., PEREL, J., & NELSON, B.
- Affiliations
- University of Pittsburgh (US)
- Corresponding author
- BIRMAHER, BORIS
- Venue
- Journal of the American Academy of Child & Adolescent Psychiatry
- Publisher
- Elsevier BV
- Published
- 1996-11
- Volume
- 35
- Issue
- 11
- Pages
- 1427-1439
- ISSN
- 0890-8567 (ISSN-L)
- OpenAlex
- W2040053981
- Cited by
- 2,076
- References
- 265
- Citations by year
- 2026: 6 · 2025: 19 · 2024: 20 · 2023: 27 · 2022: 52 · 2021: 55 · 2020: 63 · 2019: 59 · 2018: 52 · 2017: 62 · 2016: 69 · 2015: 80 · 2014: 117 · 2013: 96 · 2012: 89
- FWCI
- 12.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the American Academy of Child & Adolescent Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- NIMH (MH46894)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Keywords
- childhood depression, adolescent depression, dysthymia, familial recurrence, psychiatric comorbidity, substance abuse, bipolar disorder, suicide risk, risk factors, pathogenesis, psychosocial outcomes, educational outcomes
- MeSH terms
- Adolescent, Attention Deficit Disorder with Hyperactivity, Child, Child Behavior Disorders, Female, Humans, Male, Mass Screening, Personality Assessment, Psychiatric Status Rating Scales, Sampling Studies, Comorbidity
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