Cited by 175Schizophrenia research and treatmentSubstance Abuse Treatment and OutcomesMental Health Treatment and Access

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Epidemiological Analysis of Alcohol and Drug Use as Risk Factors for Psychotic Experiences

TIEN, ALLEN Y., ANTHONY, JAMES C.·1990·The Journal of Nervous and Mental Disease

DOI 10.1097/00005053-199008000-00001

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Abstract

Clinical and laboratory studies link alcohol and other drug use to the occurrence of psychotic experiences, but epidemiologic evidence has been lacking. In this study, the quantitative relationships between alcohol or other drug use and psychotic experiences were examined by analysis of prospective data from 4994 adult household residents sampled in a multisite survey of mental disorders in the population, the NIMH Epidemiologic Catchment Area Program. After control for sociodemographic factors and preexisting psychiatric conditions, the risk for onset of self-reported delusions or hallucinations was observed to be greater for daily users of marijuana or cocaine and for users of anxiolytics or sympathomimetics compared with nonusers. After control for daily cocaine use and alcohol disorder, the risk of onset of psychotic experiences for daily users of marijuana was double that for nonusers. Alcohol disorder in men was associated with eightfold risk and in women with threefold risk. Baseline depressive episodes, manic episodes, agoraphobia, and obsessive-compulsive disorder also were associated with increased risk of onset of psychotic experiences. — J Nerv Ment Dis 178:473-480, 1990

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Pignon, B., Sescousse, G., Amad, A., Benradia, I., Vaïva, G., Thomas, P., Geoffroy, P. A., Roelandt, J.-L., & Rolland, B. (2019) · Alcohol and Alcoholism · doi:10.1093/alcalc/agz077 · Cited by 16

Authors: TIEN, A. Y., & ANTHONY, J. C.
Affiliations: Johns Hopkins University (US)
ORCID: TIEN, ALLEN Y.
ANTHONY, JAMES C.
Venue: The Journal of Nervous and Mental Disease
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 1990-08
Volume: 178
Issue: 8
Pages: 473-480
ISSN: 0022-3018 (ISSN-L)
DOI: 10.1097/00005053-199008000-00001
OpenAlex: W2019502220
Cited by: 175
References: 0
Citations by year: 2026: 1 · 2025: 1 · 2024: 2 · 2023: 3 · 2022: 3 · 2021: 2 · 2020: 9 · 2019: 3 · 2018: 5 · 2017: 7 · 2016: 8 · 2015: 6 · 2014: 7 · 2013: 6 · 2012: 5
FWCI: 4.56
Type: journal article
Language: en
Open access: closed
Locations: The Journal of Nervous and Mental Disease (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5r01mh041908-04, 5r01da003992-04)
National Institute of Mental Health (MH41908, MH-14592, T32MH014592)
National Institute on Drug Abuse (DA03992)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
Keywords: alcohol consumption, drug use, psychotic experiences, delusions, hallucinations, cannabis, cocaine, anxiolytics, sympathomimetic drugs, alcohol-related disorders, substance use risk factors, depressive episodes, manic episodes, agoraphobia, obsessive-compulsive disorder
MeSH terms: Alcoholism, Mental Disorders, Marijuana Abuse, Cocaine, Delusions, Epidemiologic Methods, Hallucinations, Humans, Prospective Studies, Psychiatric Status Rating Scales, Psychotic Disorders, Risk Factors, Substance-Related Disorders

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Epidemiological Analysis of Alcohol and Drug Use as Risk Factors for Psychotic Experiences

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