Neurons May Live for Decades with Neurofibrillary Tangles

Biomarkers and Target-Specific Small-Molecule Drugs in Alzheimer’s Diagnostic and Therapeutic Research: From Amyloidosis to Tauopathy

Li, S., & Bhalla, R. (2024) · Neurochemical Research · doi:10.1007/s11064-024-04178-w · Cited by 8

Tau Fibrillation Induced by Heparin or a Lysophospholipid Show Different Initial Oligomer Formation

Rasmussen, H. Ø., Nielsen, J., de Poli, A., Otzen, D. E., & Pedersen, J. S. (2023) · Journal of Molecular Biology · doi:10.1016/j.jmb.2023.168194 · Cited by 7

The Role of Glycogen Synthase Kinase-3 (GSK-3) in Alzheimer’s Disease

Medina, M., & Avil, J. (2011) · InTech eBooks · doi:10.5772/16879 · Cited by 7

Direct determination of the proportion of intra- and extra-cellular neocortical neurofibrillary tangles in Alzheimer’s disease

Vickers, J. C., Tan, A., & Dickson, T. C. (2003) · Brain Research · doi:10.1016/s0006-8993(03)02429-6 · Cited by 7

Hippocampal sclerosis in the parkinsonism‐dementia complex of G uam: quantitative examination of neurons, neurofibrillary tangles, and TDP ‐43 immunoreactivity in CA1

Oyanagi, K., Yamazaki, M., Hashimoto, T., Asakawa, M., Wakabayashi, K., & Takahashi, H. (2015) · Neuropathology · doi:10.1111/neup.12185 · Cited by 7

Neuropathologie und biologische Marker degenerativer Demenzen

Jellinger, K. A., & Rösler, N. (2000) · Der Internist · doi:10.1007/s001080050557 · Cited by 7

Neuropathologie der Demenzen

Ka, J. (2001) · Journal für Kardiologie (Krause & Pachernegg GmbH) · Cited by 7

Entwined processes in Alzheimer's disease: Brain cellular senescence and Alzheimer's disease pathology

Li, W., Han, Y., Wang, P., & Qiao, S. (2025) · Alzheimer s & Dementia · doi:10.1002/alz.70803 · Cited by 6

Apoptosis vs Nonapoptotic Mechanisms in Neurodegeneration

Jellinger, K. A. (2003) · Humana Press eBooks · doi:10.1007/978-1-59259-297-5_2 · Cited by 6

Oxidative Stress and Neurodegeneration: An Inevitable Consequence of Aging? Implications for Therapy

Rodrigues, R., Bonda, D., Perry, G. L., Castellani, R. J., Casadesús, G., Lee, H., Lee, H. P., Wang, X., Zhu, X., Petersen, R. B., et al. (2010) · Springer eBooks · doi:10.1007/978-90-481-8553-5_10 · Cited by 6

La apoptosis en las enfermedades neurodegenerativas: evidencias y controversias

Jiménez-Del-Río, M., & Velez‐Pardo, C. (2001) · Revista de Neurología · doi:10.33588/rn.3209.2000495 · Cited by 6

Mitochondrial Quality Control in Alzheimer’s Disease: Insights from Caenorhabditis elegans Models

Ganguly, U., Carroll, T., Nehrke, K. W., & Johnson, G. V. W. (2024) · Antioxidants · doi:10.3390/antiox13111343 · Cited by 5

Making tau amyloid models in vitro: a crucial and underestimated challenge

Broc, J., Piersson, C., & Fichou, Y. (2025) · FEBS Letters · doi:10.1002/1873-3468.70022 · Cited by 5

Metabotropic glutamate receptors and cognition: From underlying plasticity and neuroprotection to cognitive disorders and therapeutic targets

Hoglund, B. K., Carfagno, V. F., Olive, M. F., & Leyrer‐Jackson, J. M. (2022) · International review of neurobiology · doi:10.1016/bs.irn.2022.10.004 · Cited by 4

Oncogenic parallels in Alzheimer disease

Raina, A. K., Garrett, M. R., Previll, L. A., Obrenovich, M. E., Hartzler, A., Webber, K. M., Casadesús, G., Lee, H., Perry, G. L., Zhu, X., et al. (2006) · OhioLink ETD Center (Ohio Library and Information Network) · Cited by 4

Addressing the Complex Etiology of Alzheimer‘s Disease: the Role of P25/Cdk5

Mungenast, A. E., & Tsai, L. (2011) · Future Neurology · doi:10.2217/fnl.11.22 · Cited by 3

Neurofibrillary Tangle Formation as a Protective Response to Oxidative Stress in Alzheimer’s Disease

Nunomura, A., Takeda, A., Moreira, P. I., Castellani, R. J., Lee, H., Zhu, X., Smith, M. A., & Perry, G. L. (2009) · Springer eBooks · doi:10.1007/978-0-387-87995-6_9 · Cited by 3

Early Presymptomatic Stages

Braak, H., & Tredici, K. D. (2014) · Advances in anatomy, embryology and cell biology · doi:10.1007/978-3-319-12679-1_5 · Cited by 2

Dementias Caused by Persistent Pathogens and the Protective Role of HLA Against them

James, L. M., & Georgopoulos, A. P. (2020) · Journal of Neurology and Neuromedicine · doi:10.29245/2572.942x/2019/1.1260 · Cited by 2

EFhd2 co-aggregates with monomeric and filamentous tau in vitro

Soliman, A. S., Umstead, A., Lamp, J. A., & Vega, I. E. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1373410 · Cited by 2

Current and future treatments of memory complaints and Alzheimer’s disease

Summers, W. K. (2011) · Therapy · doi:10.2217/thy.11.60 · Cited by 2

Demenz

Knell, S., Thal, D. R., & Lipp, V. (2022) · Verlag Karl Alber eBooks · doi:10.5771/9783495999370 · Cited by 2

Is there room for Darwinian medicine and the hygiene hypothesis in Alzheimer pathogenesis?

Griffin, W. S. T., & Mrak, R. E. (2009) · Birkhäuser Basel eBooks · doi:10.1007/978-3-7643-8903-1_14 · Cited by 2

Use of bomb pulse 14C to age senile plaques and neurofibrillary tangles in the Alzheimer's disease brain

Robertson, J. D., Lovell, M. A., Buchholz, B. A., Xie, C., & Markesbery, W. R. (2001) · Journal of Radioanalytical and Nuclear Chemistry · doi:10.1023/a:1013299426601 · Cited by 2

Frequency and distribution of TUNEL‐positive neurons in brains of dementia with Lewy bodies: Comparison with those in brains of Alzheimer's disease

Katsuse, O., Iseki, E., Suzuki, K., & Kosaka, K. (2001) · Neuropathology · doi:10.1046/j.1440-1789.2001.00411.x · Cited by 2

Correlation between tau phosphorylation sites and tangle morphology in Alzheimer's disease

Shimazaki, M., NAKANO, H., & Kobayashi, K. (2005) · Psychogeriatrics · doi:10.1111/j.1479-8301.2005.00087.x · Cited by 2

Role of Oxidative Insult and Neuronal Survival in Alzheimer’s and Parkinson’s Diseases

Nunomura, A., Moreira, P. I., Zhu, X., Cash, A., Smith, M. A., & Perry, G. L. (2007) · Springer eBooks · doi:10.1007/978-0-387-72076-0_14 · Cited by 2

Tau Oligomers as Potential Drug Target for Alzheimer Disease (AD) Treatment

Kayed, R. (2011) · InTech eBooks · doi:10.5772/16682 · Cited by 1

Significance of Neurofibrillary Tangles in Alzheimer’s Disease—Lessons from Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17

Ihara, Y. (2002) · Advances in behavioral biology · doi:10.1007/978-0-306-47593-1_5 · Cited by 1

Place cell physiology in a transgenic mouse model of Alzheimer's disease

Yi, M. (2009) · Cited by 1

Alzheimer’s Disease

Ikezu, T. (2016) · Springer eBooks · doi:10.1007/978-3-319-44022-4_30 · Cited by 1

One Autopsy Proved Neocortical Lewy Body Disease Without the Involvement of the Olfactory Bulb and Brainstem

Chung, E. J., Cho, H. J., Hur, D. Y., Kim, Y. S., Lee, K., & Kim, S. J. (2022) · Journal of Korean Medical Science · doi:10.3346/jkms.2022.37.e195 · Cited by 1

Serotonin receptors - a potential target for the treatment of Alzheimer’s disease

Eremin, D. V., Kondaurova, E. M., Rodnyy, A. Y., Molobekova, K. A., Kudlay, D. A., & Naumenko, V. S. (2023) · Biochemistry (Moscow) · doi:10.31857/s0320972523120059 · Cited by 1

Alzheimer Disease: Oxidative Stress and Compensatory Responses

Moreira, P. I., Nunomura, A., Zhu, X., Lee, H., Aliev, G., Smith, M. A., & Perry, G. L. (2009) · Contemporary clinical neuroscience · doi:10.1007/978-1-60327-342-8_7 · Cited by 1

Epigenetics in mental and neurodegenerative disorders

Iatrou (2018) · Research Publications (Maastricht University) · doi:10.26481/dis.20180712ai · Cited by 1

The Role of ATP and P2X Purinoceptor 7 in the Development of Cerebral Tau

Gao, A. F. (2018) · TSpace (University of Toronto) · Cited by 1

The Role of Lipoproteins/cholesterol in Genomic Instability and Chromosome Mis-segregation in Alzheimer's and Cardiovascular Disease

Granic, A. (2011) · Digital Commons - University of South Florida (University of South Florida)

Angiotensin-II-Rezeptorantagonisten und endotheliale Progenitorzellen: ein neuer therapeutischer Ansatz?

Hochegger, K., & Ar, R. (2007) · Journal für Kardiologie (Krause & Pachernegg GmbH)

Modulation of growth factor-induced ERK signaling by the microtubule associated protein tau

Leugers, C. J. (2010) · doi:10.17077/etd.44cmdeo5

The role of mTor in the pathogenesis of tau-related pathologies in Alzheimer Disease

Tang, Z. (2014) · Figshare

Mouse and stem cell models of frontotemporal dementia

Orr, M. E. (2012) · Montana State University ScholarWorks (Montana State University)

Alzheimer´s disease and apolipoprotein E.A prospective, population-based molecular genetic and neuropathological study of individuals aged 85 years or more

Polvikoski, T. M. (2004) · Työväentutkimus Vuosikirja

Acción protectora de la proteína tau en la enfermedad de Alzheimer

Luna‐Muñoz, J., Zamudio, S., de la Cruz, F., Minjarez-Vega, B., & Mena, R. (2012)

Targeting Tau Aggregation for the Diagnosis and Treatment of Alzheimer's Disease

Schafer, N. D. (2013) · OhioLink ETD Center (Ohio Library and Information Network)

Análise de danos ao DNA e expressão de genes supressores de tumor em tecido post mortem de pacientes com doença de Alzheimer

dos Santos, A. C. F., & dos Santos (2012)

Genetic Models of Alzheimer’s Disease: The Influence of Apolipoprotein E allele Isoforms on Behaviour in Laboratory Animals

Albrecht, M. A., & Foster, J. K. (2016) · Springer eBooks · doi:10.1007/978-1-4939-3777-6_7

Amyloid- _ and _ in Alzheimer’s Disease

Nunomura, A., Lee, H., Zhu, X., Perry, G. L., Castellani, R. J., & Smith, M. A. (2005) · Oxidative stress and disease · doi:10.1201/9781420026559.ch6

Oxidative Adaptation in Aging and Alzheimer’s Disease

Hirai, K., Takeda, A., Nunomura, A., Smith, M. A., Lee, H., Zhu, X., Joseph, J. A., Perry, G. L., & Drew, K. L. (2005) · Oxidative stress and disease · doi:10.1201/9781420027174.ch11

Approach for Alzheimer's Disease

Tian, H. (2014)

Proxy-PET Building Blocks as a Design Element for Library Synthesis

Mallin, L. J. (2015) · Journal of Bioresource Management

Tangled tau: Active pathology or footprint of disease?

Higham, J. P. (2017) · Alzheimer s & Dementia Translational Research & Clinical Interventions · doi:10.1016/j.trci.2017.10.007

Identifying stage-specific markers of Alzheimer's disease using quantitative proteomics

Yagensky, O. (2018) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-7052

THE ROLE OF MICROTUBULE-ASSOCIATED PROTEIN TAU IN NEURONAL EXCITABILITY AND EPILEPTOGENESIS

Cloyd, R. (2021) · UKnowledge (University of Kentucky) · doi:10.13023/etd.2021.271

Faculty Opinions recommendation of Questions concerning the role of amyloid-β in the definition, aetiology and diagnosis of Alzheimer's disease.

Ashford, J. W. (2018) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.734280398.793553881

I. Demenz: Medizinische Aspekte

Knell, S., Thal, D. R., & Lipp, V. (2022) · Verlag Karl Alber eBooks · doi:10.5771/9783495999370-17

The contribution of oligodendrocytes to amyloid and tau pathologies in mouse models of Alzheimer’s disease

Sasmita, A. O. (2024) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-10403

Alzheimer’s Disease

Ikezu, T. (2024) · Springer eBooks · doi:10.1007/978-3-031-68237-7_22

Microglial glutathione and glutamate: regulation mechanisms

Fry, V. A. H. (2009) · UCL Discovery (University College London)

PKD1-tau disulfide linkage promotes tau phosphorylation and tau accumulation in a tauopathy mouse modelPreprint

Ye, J., Yue, R.-Z., Li, C., Wu, L., Guo, X., Zhao, Y., Wan, H., Wang, J.-Z., Gu, B., & Xiao, S. (2025) · Research Square · doi:10.21203/rs.3.rs-7655539/v1

Oxidative Stress Associated Signal Transduction Cascades in Alzheimer Disease

Petersen, R. B., Nunomura, A., Lee, H., Casadesús, G., Perry, G. L., Smith, M. A., & Zhu, X. (2009) · Contemporary clinical neuroscience · doi:10.1007/978-1-60327-342-8_8

Tau nucléaire : un acteur clé dans le stress neuronal

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Intégrité de la barrière hémato-encéphalique et transport du peptide bêta-amyloïde dans la maladie d'Alzheimer

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Génération de cellules souches pluripotentes induites de patients Alzheimer et production d'un modèle de culture en trois dimensions de neurones pour les recherches diagnostiques et thérapeutiques de la maladie d’Alzheimer

Auboyer, L. (2018) · theses.fr (ABES) · doi:10.70675/07243ef7zb974z4ad8z97d9zd046801798b1

Rôle de la neuroinflammation et du récepteur microglial TREM2 dans la progression de deux modèles de tauopathie

Vautheny, A. (2019) · theses.fr (ABES) · doi:10.70675/1812d71aze8d9z48d6z87d1z5a23a4e81953

Étude biophysique de l'interaction protéine tau - zinc

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Les organoïdes cérébraux : nouvelle plateforme pour la modélisation de pathologies neurodéveloppementales et neurodégénératives

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Engrailed, a target of the miR-92 family, attenuates Tau accumulation and associated memory deficits in Drosophila

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Humanized tauopathy chimeras uncover microglial and lncRNA strategies for neuroprotectionPreprint

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Investigating the role of EFhd2 protein in modulating tau pathology in a tauopathy mouse model

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Neuronal and glial transcriptional states vary with proximity to tangle-bearing neurons in the human entorhinal cortexPreprint

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Duration of neurofibrillary changes in the hippocampal pyramidal neurons

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Neuron loss from the hippocampus of Alzheimer's disease exceeds extracellular neurofibrillary tangle formation

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On the survival time of a tangled neuron in the hippocampal CA4 region in parkinsonism dementia complex of Guam

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Stereologic Evidence for Persistence of Viable Neurons in Layer II of the Entorhinal Cortex and the CA1 Field in Alzheimer Disease

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Neuronal loss and neurofibrillary degeneration in the hippocampal cortex in late-onset sporadic Alzheimer’s disease

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