The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Correlates and Predictors of Adherence to Highly Active Antiretroviral Therapy: Overview of Published Literature
Abstract
Knowledge of factors associated with medication adherence could help HIV clinicians to target persons in need of intervention, design these interventions, and help researchers to plan studies of adherence. This review summarizes the results of 20 studies investigating the issue of barriers to optimal highly active antiretroviral therapy (HAART) adherence. Only a few determinants were consistently associated with nonadherence. Symptoms and adverse drug effects, psychologic distress, lack of social or family support, complexity of the HAART regimen, low patient self-efficacy, and inconvenience of treatment were the factors most consistently associated with nonadherence. There were inconsistent findings regarding the relationship of adherence and the following variables: sociodemographic characteristics, substance abuse, depressive symptoms, quality of life, CD4+ cell count, knowledge and beliefs about treatment, patients' satisfaction with health care, and patient-provider relationship. A synthesis of findings relating various factors to adherence to HAART is difficult to reach because of several limitations of the existing body of research. These limitations concern the measurement of adherence, the assessment of correlates and predictors of adherence, the study population, and the study design.
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Citations
Cites
Adherence to Protease Inhibitor Therapy and Outcomes in Patients with HIV Infection
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A Comparison Study of Multiple Measures of Adherence to HIV Protease Inhibitors
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Sociodemographic and psychological variables influencing adherence to antiretroviral therapy
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Self-citation
Cited by
Osterberg, L., & Blaschke, T. (2005) · New England Journal of Medicine · doi:10.1056/nejmra050100 · Cited by 7,974
Patient adherence to medical treatment: a review of reviews
van Dulmen, S., Sluijs, E., van Dijk, L., de Ridder, D., Heerdink, R., & Bensing, J. (2007) · BMC Health Services Research · doi:10.1186/1472-6963-7-55 · Cited by 627
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Langebeek, N., Gisolf, E. H., REISS, P. C., Vervoort, S. C. J. M., Hafsteinsdøttir, T. B., Richter, C., Sprangers, M. A. G., & Nieuwkerk, P. T. (2014) · BMC Medicine · doi:10.1186/preaccept-1453408941291432 · Cited by 405
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Metadata
- Authors
- Ammassari, A., Trotta, M. P., Murri, R., Castelli, F., Narciso, P., Noto, P., Vecchiet, J., Monforte, A. D., Wu, A. W., & Antinori, A.
- Venue
- JAIDS Journal of Acquired Immune Deficiency Syndromes
- Published
- 2002-12
- Volume
- 31
- Pages
- S123-S127
- ISSN
- 1525-4135 (ISSN-L)
- OpenAlex
- W2062071417
- Cited by
- 480
- References
- 28
- FWCI
- 8.71
- Type
- journal article
- Language
- en
- Open access
- closed
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- Ammassari, A., Trotta, M. P., Murri, R., Castelli, F., Narciso, P., Noto, P., Vecchiet, J., Monforte, A. D., Wu, A. W., & Antinori, A. (2002). Correlates and Predictors of Adherence to Highly Active Antiretroviral Therapy: Overview of Published Literature. JAIDS Journal of Acquired Immune Deficiency Syndromes. https://doi.org/10.1097/00126334-200212153-00007
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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