Cited by 149Schizophrenia research and treatmentAging, Health, and DisabilityMental Health and Psychiatry

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Assessing Disability in Older Patients With Schizophrenia: Results From the WHODAS-II

McKibbin, Christine, Patterson, Thomas L., Jeste, Dilip V.·2004·Journal of Nervous & Mental Disease

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Abstract

The World Health Organization has recently published an instrument to evaluate disability, entitled the World Health Organization Disability Assessment Schedule-Second Version (WHODAS-II). We sought to evaluate its reliability and validity in older patients with schizophrenia. We studied 54 outpatients with schizophrenia and 22 normal comparison subjects. Besides WHODAS-II, we used standardized rating scales to assess positive and negative symptoms, depressive symptoms, cognitive functioning, everyday functioning, and quality of well-being. There was high internal consistency in WHODAS-II item scores and significant test-retest reliability. Patients reported greater disability than normal comparison subjects. Among the patients, disability scores were significantly associated with severity of depressive symptoms and quality of well-being, but not with cognitive performance and everyday functioning. The findings offer strong evidence for reliability and some evidence for validity of the WHODAS-II in older patients with schizophrenia.

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Authors: McKibbin, C., Patterson, T. L., & Jeste, D. V.
Affiliations: University of California San Diego (US)
Corresponding author: McKibbin, Christine
Patterson, Thomas L.
Jeste, Dilip V.
ORCID: McKibbin, Christine
Patterson, Thomas L.
Jeste, Dilip V.
Venue: Journal of Nervous & Mental Disease
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2004-06
Volume: 192
Issue: 6
Pages: 405-413
ISSN: 0022-3018 (ISSN-L)
DOI: 10.1097/01.nmd.0000130133.32276.83
OpenAlex: W2012563051
Cited by: 149
References: 43
Citations by year: 2026: 1 · 2025: 1 · 2024: 5 · 2023: 3 · 2022: 11 · 2021: 8 · 2020: 9 · 2019: 7 · 2018: 5 · 2017: 2 · 2016: 6 · 2015: 5 · 2014: 13 · 2013: 3 · 2012: 9
FWCI: 3.13
Type: journal article
Language: en
Open access: closed
Locations: The Journal of Nervous and Mental Disease (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Mental Health (MH49671, R01MH059101, R01MH062554, MH-43693, MH59101, R01 MH62554, P30MH66248, P30MH049671, K23MH063139, P30MH066248)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Aging, Health, and Disability
Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
Keywords: schizophrenia, older adults, disability assessment, WHODAS II, reliability statistics, validity, depressive symptoms, quality of well-being, cognitive function, daily functioning, positive and negative symptoms
MeSH terms: Activities of Daily Living, Age Factors, Cognition Disorders, Disability Evaluation, Female, Humans, Male, Middle Aged, Neuropsychological Tests, Personality Inventory, Psychiatric Status Rating Scales, Psychometrics, Psychotic Disorders, Quality of Life, Surveys and Questionnaires, Schizophrenia, Schizophrenic Psychology, Reproducibility of Results, International Classification of Diseases, Assisted Living Facilities

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Assessing Disability in Older Patients With Schizophrenia: Results From the WHODAS-II

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