Enteral Nutrition Can Be Given to Patients on Vasopressors
Open accessAbstract
Duke University Hospital, Department of Anesthesiology and Duke Clinical Research Institute, Durham NC. Dr. Wischmeyer's institution received funding from Abbott, Fresenius, and the National Institutes of Health (NIH); he has received grant funding related to this work from NIH, Canadian Institutes of Health Research, Abbott, Baxter, Fresenius, and Takeda; he has served as a consultant to Abbott, Fresenius, Baxter, Cardinal Health, Nutricia, and Takeda for research related to this work; he has an unrestricted gift donation for surgical nutrition research from Musclesound and Cosmed, he has received honoraria or travel expenses for continuing medical education lectures on improving nutrition care from Abbott, Baxter, and Nutricia. For information regarding this article, E-mail: [email protected]
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Patients with septic shock are particularly vulnerable to complications of enteral feeding due to the need for high-dose vasopressor support, the risk of low gastrointestinal tract perfusion, and the potential for mesenteric ischemia or non-occlusive bowel necrosis.
“Patients with septic shock are particularly vulnerable due to the need for high-dose vasopressor support, the risk of low GI tract perfusion, and the potential for complications such as mesenteric ischemia or, in severe cases, non-occlusive bowel necrosis upon initiation of EF [3,12].”
From The impact of enteral feeding intolerance on the prognosis of patients with septic shock in South Korea (2025) · cites this paper as [12]
In the main text (page unavailable), the paper says vasopressors at sufficient doses can be associated with bowel injury and identifies mesenteric ischemia and non-occlusive bowel necrosis as valid concerns when feeding patients on vasopressors. It also describes impaired gut perfusion in septic shock. However, it says most bowel-ischemia cases present late in the feeding course, contrary to the claim’s implication that these complications typically occur upon initiation of enteral feeding. (LLM, conf=0.88)
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- Authors
- Wischmeyer, P. E.
- Affiliations
- Duke University Hospital (US)
- Corresponding author
- Wischmeyer, Paul E.
- ORCID
- Wischmeyer, Paul E.
- Venue
- Critical Care Medicine
- Published
- 2020-01
- Volume
- 48
- Issue
- 1
- Pages
- 122-125
- ISSN
- 0090-3493 (ISSN-L)
- PMC
- PMC8101503
- OpenAlex
- W2967558441
- Cited by
- 53
- References
- 26
- Citations by year
- 2026: 7 · 2025: 11 · 2024: 10 · 2023: 6 · 2022: 6 · 2021: 7 · 2020: 6
- FWCI
- 3.61
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Critical Care Medicine (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Canadian Institutes of Health Research
- National Heart, Lung, and Blood Institute (R34HL109369)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
- Health Sciences › Medicine › Surgery › Hemodynamic Monitoring and Therapy
- Health Sciences › Medicine › Surgery › Enhanced Recovery After Surgery
- Keywords
- enteral nutrition, vasopressors, critically ill patients, nutritional support, septic shock
- MeSH terms
- Critical Care, Enteral Nutrition, Humans, Vasoconstrictor Agents, Critical Illness, Practice Guidelines as Topic
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