The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Inflammation and coagulation
Abstract
In the pathogenesis of sepsis, inflammation and coagulation play a pivotal role. Increasing evidence points to an extensive cross-talk between these two systems, whereby inflammation leads to activation of coagulation, and coagulation also considerably affects inflammatory activity. Molecular pathways that contribute to inflammation-induced activation of coagulation have been precisely identified. Pro-inflammatory cytokines and other mediators are capable of activating the coagulation system and down-regulating important physiologic anticoagulant pathways. Activation of the coagulation system and ensuing thrombin generation is dependent on expression of tissue factor and the simultaneous down-regulation of endothelial-bound anticoagulant mechanisms and endogenous fibrinolysis. Conversely, activated coagulation proteases may affect specific cellular receptors on inflammatory cells and endothelial cells and thereby modulate the inflammatory response.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Taylor, F., Toh, C.-H., Hoots, K., Wada, H., & Levi, M. (2001) · Thrombosis and Haemostasis · doi:10.1055/s-0037-1616068 · Cited by 2,285
Self-citationTreating Patients with Severe Sepsis
Wheeler, A. P., & Bernard, G. R. (1999) · New England Journal of Medicine · doi:10.1056/nejm199901213400307 · Cited by 992
Slofstra, S. H., Bijlsma, M. F., Groot, A. P., Reitsma, P. H., Lindhout, T., ten Cate, H., & Spek, C. A. (2007) · Blood · doi:10.1182/blood-2007-02-075440 · Cited by 66
Cited by
The Pathogenesis of Sepsis and Potential Therapeutic Targets
Huang, M., Cai, S., & Su, J. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20215376 · Cited by 776
Erin, N., Grahovac, J., Brozovic, A., & Efferth, T. (2020) · Drug Resistance Updates · doi:10.1016/j.drup.2020.100715 · Cited by 527
Pathogenesis and Pathophysiology of Pneumococcal Meningitis
Mook-Kanamori, B. B., Geldhoff, M., van der Poll, T., & van de Beek, D. (2011) · Clinical Microbiology Reviews · doi:10.1128/cmr.00008-11 · Cited by 492
Kwaifa, I. K., Bahari, H., Yong, Y. K., & Noor, S. M. (2020) · Biomolecules · doi:10.3390/biom10020291 · Cited by 345
Incidence of Venous Thromboembolism in Patients with Cushing's Syndrome: A Multicenter Cohort Study
Stuijver, D. J. F., van Zaane, B., Feelders, R. A., Debeij, J., Cannegieter, S. C., Hermus, A. R., van den Berg, G., Pereira, A. M., de Herder, W. W., Wagenmakers, M. A. E. M., et al. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-1661 · Cited by 208
Erez, O., Mastrolia, S. A., & Thachil, J. (2015) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2015.03.054 · Cited by 170
Horiguchi, H., Loftus, T. J., Hawkins, R. B., Raymond, S. L., Stortz, J. A., Hollen, M. K., Weiss, B. P., Miller, E. S., Bihorac, A., Larson, S. D., et al. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00595 · Cited by 164
Effect of MSCs and MSC-Derived Extracellular Vesicles on Human Blood Coagulation
Silachev, D., Goryunov, K., Shpilyuk, M., Beznoschenko, O., Morozova, N., Kraevaya, E., Popkov, V., Pevzner, I., Zorova, L., Evtushenko, E., et al. (2019) · Cells · doi:10.3390/cells8030258 · Cited by 154
Ding, D., Liu, X., Duan, J., & Guo, S.-W. (2015) · Human Reproduction · doi:10.1093/humrep/dev025 · Cited by 139
Novel insights into molecular mechanisms of abruption-induced preterm birth
Buhimschi, C. S., Schatz, F., Krikun, G., Buhimschi, I. A., & Lockwood, C. J. (2010) · Expert Reviews in Molecular Medicine · doi:10.1017/s1462399410001675 · Cited by 53
Inflammatory and coagulatory parameters linked to survival in critically ill children with sepsis
Niederwanger, C., Bachler, M., Hell, T., Linhart, C., Entenmann, A., Balog, A., Auer, K., & Innerhofer, P. (2018) · Annals of Intensive Care · doi:10.1186/s13613-018-0457-8 · Cited by 34
Predictive Ability of Preoperative PT-INR and Postoperative MCP1 for Post-hepatectomy Liver Failure
ARISAKA, S., MATSUYAMA, R., GOTO, K., SUWA, Y., MORI, R., MORIOKA, D., TAGURI, M., & ENDO, I. (2020) · In Vivo · doi:10.21873/invivo.11899 · Cited by 9
ZHANG, X., LUAN, Z., LIANG, Y., LIU, Y., & MA, X. (2015) · Molecular Medicine Reports · doi:10.3892/mmr.2015.3251 · Cited by 8
Metadata
- Authors
- Levi, M., & van der Poll, T.
- Venue
- Critical Care Medicine
- Published
- 2010-02
- Volume
- 38
- Issue
- 2 Suppl
- Pages
- S26-S34
- ISSN
- 0090-3493 (ISSN-L)
- OpenAlex
- W1989528047
- Cited by
- 984
- References
- 3
- FWCI
- 31.96
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
