The influence of acutely administered nicotine on cue-induced craving for gambling in at-risk video lottery terminal gamblers who smoke
Abstract
Evidence indicates that tobacco use and gambling often co-occur. Despite this association, little is known about how tobacco use affects the propensity to gamble. Nicotine, the putative addictive component of tobacco, has been reported to potentiate the hedonic value of other nonsmoking stimuli. Environmental cues have been identified as an important contributor to relapse in addictive behavior; however, the extent to which nicotine can affect the strength of gambling cues remains unknown. This study examined whether nicotine influences subjective ratings for gambling following gambling cues. In a mixed within/between-subjects design, 30 (20 men) video lottery terminal (VLT) gamblers ('moderate-risk' or 'problem' gamblers) who smoke daily were assigned to nicotine (4 mg deliverable) or placebo lozenge conditions. Subjective and behavioral responses were assessed at baseline, following lozenge, following neutral cues, and following presentation of gambling cues. Nicotine lozenge was found to significantly reduce tobacco-related cravings (P<0.05) but did not affect gambling-related cravings, the choice to play a VLT, or other subjective responses. These results suggest that a low dose of acutely administered nicotine does not increase cue-induced craving for gambling in at-risk VLT gamblers who smoke.
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Individuals playing blackjack in a gambling-like environment reported greater urges to gamble than those in a neutral context.
“For example, individuals playing blackjack in a gambling-like environment reported greater urges to gamble than those in a neutral context (Kushner et al., 2008; McGrath, Dorbeck, & Barrett, 2013).”
From Cued for Risk: Evidence for an Incentive Sensitization Framework to Explain the Interplay between Stress and Anxiety, Substance Abuse, and Reward Uncertainty in Disordered Gambling Behavior (2019) · cites this paper as McGrath, Dorbeck, & Barrett, 2013
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Self-citationSchlagintweit, H. E. (2017) · DalSpace (Dalhousie University)
- Authors
- McGrath, D. S., Dorbeck, A., & Barrett, S. P.
- Affiliations
- Dalhousie University (CA)
- Corresponding author
- Barrett, Sean P.
- Venue
- Behavioural Pharmacology
- Published
- 2013-04
- Volume
- 24
- Issue
- 2
- Pages
- 124-132
- ISSN
- 0955-8810 (ISSN-L)
- OpenAlex
- W2334132018
- Cited by
- 14
- References
- 43
- Citations by year
- 2023: 1 · 2022: 1 · 2021: 1 · 2020: 1 · 2019: 1 · 2018: 3 · 2017: 1 · 2015: 2 · 2014: 3
- FWCI
- 1.85
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Behavioural Pharmacology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Nova Scotia Health Research Foundation
- Dalhousie University
- Topics
- Social Sciences › Psychology › Clinical Psychology › Gambling Behavior and Treatments
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Nicotinic Acetylcholine Receptors Study
- Keywords
- nicotine, gambling cues, cue-induced craving, video lottery terminals, problem gambling, tobacco use, co-occurring addiction, nicotine lozenges, gambling behavior
- MeSH terms
- Smoking Prevention, Adult, Cues, Double-Blind Method, Female, Gambling, Humans, Male, Nicotine, Nova Scotia, Surveys and Questionnaires, Reinforcement, Psychology, Smoking, Tobacco Use Disorder, Behavior, Addictive, Video Games, Tobacco Use Cessation, Young Adult, Tobacco Use Cessation Devices
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