The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Dried Blood Spot Methods in Therapeutic Drug Monitoring: Methods, Assays, and Pitfalls
Abstract
This article reviews dried blood spot (DBS) sampling in therapeutic drug monitoring. The DBS method involves applying whole blood obtained via a fingerprick to a sampling paper. After drying and transportation, the blood spot is extracted and analyzed in the laboratory. Assays of many medicines in DBS have already been reported in the literature and are reviewed here. The technique involved in and factors that may influence the accuracy and reproducibility of DBS methods are also discussed. DBS sampling ultimately seems to be a useful technique for therapeutic drug monitoring that could have many advantages in comparison with conventional venous sampling. However, its benefits must be weighed against the degree of potential errors introduced via the sampling method; there is evidently a need for more standardization, quality assurance, basic research, and assay development.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Use of Tandem Mass Spectrometry for Multianalyte Screening of Dried Blood Specimens from Newborns
Chace, D. H., Kalas, T. A., & Naylor, E. W. (2003) · Clinical Chemistry · doi:10.1373/clinchem.2003.022178 · Cited by 621
Use of Filter Paper for the Collection and Analysis of Human Whole Blood Specimens
Mei, J. V., Alexander, J. R., Adam, B. W., & Hannon, W. H. (2001) · The Journal of Nutrition · doi:10.1093/jn/131.5.1631s · Cited by 579
Koal, T., Burhenne, H., Römling, R., Svoboda, M., Resch, K., & Kaever, V. (2005) · Rapid Communications in Mass Spectrometry · doi:10.1002/rcm.2158 · Cited by 207
Gestation-induced changes in lamotrigine pharmacokinetics: A monotherapy study
de Haan, G. J., Edelbroek, P., Segers, J., Engelsman, M., Lindhout, D., Dévilé-Notschaele, M., & Augustijn, P. (2004) · Neurology · doi:10.1212/01.wnl.0000133213.10244.fd · Cited by 197
Self-citationTherapeutic drug monitoring of tacrolimus with the dried blood spot method
Hoogtanders, K., van der Heijden, J., Christiaans, M., Edelbroek, P., van Hooff, J. P., & Stolk, L. M. L. (2007) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2006.11.023 · Cited by 186
Self-citationAdam, B. W., Alexander, J. R., Smith, S. J., et al. (2000) · Clinical Chemistry · doi:10.1093/clinchem/46.1.126 · Cited by 136
la Marca, G., Malvagia, S., Filippi, L., Fiorini, P., Innocenti, M., Luceri, F., Pieraccini, G., Moneti, G., Francese, S., Dani, F. R., et al. (2008) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2008.09.025 · Cited by 119
Long-Term Stability of Amino Acids and Acylcarnitines in Dried Blood Spots
Strnadová, K. A., Holub, M., Mühl, A., Heinze, G., Ratschmann, R., Mascher, H. J., Stöckler‐Ipsiroglu, S., Waldhauser, F., Votava, F., Lebl, J., et al. (2007) · Clinical Chemistry · doi:10.1373/clinchem.2006.076679 · Cited by 87
Cheung, C. Y., van der Heijden, J., Hoogtanders, K., Christiaans, M. H. L., Liu, A. Y. L., Chan, Y.-H., Choi, K. S., van de Plas, A., Shek, C. C., Chau, K., et al. (2007) · Transplant International · doi:10.1111/j.1432-2277.2007.00584.x · Cited by 79
Self-citationLejeune, D., Souletie, I., Houzé, S., Bricon, T. L., Bras, J. L., Gourmel, B., & Houzé, P. (2006) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2006.09.036 · Cited by 77
Cited by
Therapeutic Drug Monitoring in the Treatment of Tuberculosis: An Update
Alsultan, A., & Peloquin, C. A. (2014) · Drugs · doi:10.1007/s40265-014-0222-8 · Cited by 444
Therapeutic Drug Monitoring by Dried Blood Spot: Progress to Date and Future Directions
Wilhelm, A. J., den Burger, J. C. G., & Swart, E. L. (2014) · Clinical Pharmacokinetics · doi:10.1007/s40262-014-0177-7 · Cited by 342
Andrews, L. M., Li, Y., De Winter, B. C. M., Shi, Y.-Y., Baan, C. C., Van Gelder, T., & Hesselink, D. A. (2017) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1080/17425255.2017.1395413 · Cited by 142
Feasibility of and patients’ perspective on nilotinib dried blood spot self-sampling
Boons, C. C. L. M., Timmers, L., Janssen, J. J. W. M., Swart, E. L., Hugtenburg, J. G., & Hendrikse, N. H. (2019) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-019-02640-1 · Cited by 36
Jager, N. G. L., Rosing, H., Linn, S. C., Schellens, J. H. M., & Beijnen, J. H. (2015) · Therapeutic Drug Monitoring · doi:10.1097/ftd.0000000000000224 · Cited by 14
Metadata
- Authors
- Edelbroek, P. M., Heijden, J. V. D., & Stolk, L. M. L.
- Venue
- Therapeutic Drug Monitoring
- Published
- 2009-06
- Volume
- 31
- Issue
- 3
- Pages
- 327-336
- ISSN
- 0163-4356 (ISSN-L)
- OpenAlex
- W2007501521
- Cited by
- 512
- References
- 19
- FWCI
- 16.55
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
