Efficacy of isolated home blood pressure monitoring for blood pressure control: randomized controlled trial with ambulatory blood pressure monitoring – MONITOR study
Abstract
BACKGROUND: Rates of control of hypertension remain unsatisfactory worldwide and simple methods to encourage patients to adhere to treatments are still necessary. In this randomized controlled trial, we evaluated the efficacy of a protocol of home blood pressure monitoring (HBPM), without medication titration, to improve BP assessed by ambulatory BPM (ABPM). METHODS: Patients with hypertension under drug treatment and with uncontrolled BP at office and by 24-h ABPM were randomly assigned to HBPM or usual care. The treatment was not modified during the trial. Follow-up visits were conducted at 7 and 30 days after randomization, and at 60 days to assess the outcome. Deltas between baseline and final ABPM measurements were calculated for 24-h, nightly and daily ambulatory SBP and DBP. RESULTS: Of 558 patients screened, 136 fulfilled the eligibility criteria and were randomized, and 121 (89%) completed the trial. The between groups deltas (95% confidence interval) of variation of 24 h, nightly and daily SBP were 5.4 (0.9-9.8) (P = 0.018), 10.9 (2.9-18.9) (P = 0.012) and 4.4 mmHg (-0.1 to 8.8) (P = 0.055), respectively; the corresponding deltas for DBP were 4.5 (1.6-7.4) (P = 0.003), 3.4 (0.4-6.3) (P = 0.025) and 5.8 mmHg (2.5-9.0) (P = 0.001), respectively. At the end of the trial, 32.4% of patients of the HBPM groups and 16.2% of the control group had 24-h SBP less than 130/80 mmHg (P = 0.03). CONCLUSION: A protocol of HBPM without medication titration enhances the control of BP assessed by ABPM.
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BP self-monitoring has effectively promoted BP control, at the expense of medication titration or increased adherence to BP-lowering medications.
“With or without mHealth support, BP self-monitoring has effectively promoted BP control, at the expense of medication titration or increased adherence to BP-lowering medications [15,32,33].”
mHealth interventions have the potential to not only control BP, but also foster significant lifestyle modifications.
“Given the ever-increasing number of smartphone users worldwide [14], mHealth interventions have the potential to not only control BP, but also foster significant lifestyle modifications [15].”
Cites
Global burden of blood-pressure-related disease, 2001
Lawes, C. M. M., Hoorn, S. V., & Rodgers, A. (2008) · The Lancet · doi:10.1016/s0140-6736(08)60655-8 · Cited by 2,330 · see citing works
Pickering, T. G., Hall, J. E., Appel, L. J., Falkner, B. E., Graves, J., Hill, M. N., Jones, D. W., Kurtz, T., Sheps, S. G., & Roccella, E. J. (2005) · Hypertension · doi:10.1161/01.hyp.0000150859.47929.8e · Cited by 2,051 · see citing works
O'Brien, E., Asmar, R., Beilin, L., Imai, Y., Mallion, J.-M., Mancia, G., Mengden, T., Myers, M., Padfield, P., Palatini, P., et al. (2003) · Journal of Hypertension · doi:10.1097/00004872-200305000-00001 · Cited by 1,655 · see citing works
Sega, R., Facchetti, R., Bombelli, M., Cesana, G., Corrao, G., Grassi, G., & Mancia, G. (2005) · Circulation · doi:10.1161/01.cir.0000160923.04524.5b · Cited by 1,009 · see citing works
Random allocation software for parallel group randomized trials
Saghaei, M. (2004) · BMC Medical Research Methodology · doi:10.1186/1471-2288-4-26 · Cited by 793 · see citing works
Pereira, M., Lunet, N., Azevedo, A., & Barros, H. (2009) · Journal of Hypertension · doi:10.1097/hjh.0b013e3283282f65 · Cited by 626 · see citing works
McManus, R., Mant, J., Bray, E., Holder, R., Jones, M. I., Greenfield, S., Kaambwa, B., Banting, M., Bryan, S., Little, P., et al. (2010) · The Lancet · doi:10.1016/s0140-6736(10)60964-6 · Cited by 552 · see citing works
European Society of Hypertension Practice Guidelines for home blood pressure monitoring
Parati, G., Stergiou, G. S., Asmar, R., Bilo, G., de Leeuw, P., Imai, Y., Kario, K., Lurbe, E., Manolis, A., Mengden, T., et al. (2010) · Journal of Human Hypertension · doi:10.1038/jhh.2010.54 · Cited by 482 · see citing works
Agarwal, R., Bills, J. E., Hecht, T. J. W., & Light, R. P. (2011) · Hypertension · doi:10.1161/hypertensionaha.110.160911 · Cited by 430 · see citing works
Bray, E. P., Holder, R., Mant, J., & McManus, R. J. (2010) · Annals of Medicine · doi:10.3109/07853890.2010.489567 · Cited by 245 · see citing works
Verberk, W., Kroon, A., Lenders, J., Kessels, A., van Montfrans, G. V., Smit, A., van der Kuy, P. M., Nelemans, P., Rennenberg, R., Grobbee, D., et al. (2007) · HYPERTENSION · doi:10.1161/hypertensionaha.107.094193 · Cited by 179 · see citing works
Parati, G., Omboni, S., Albini, F., Piantoni, L., Giuliano, A., Revera, M., Illyes, M., & Mancia, G. (2009) · Journal of Hypertension · doi:10.1097/hjh.0b013e3283163caf · Cited by 166 · see citing works
Contreras, E. M., Claros, N. M., Gil-Guillén, V. F., Wichmann, M. D. L. F.-V., Casado-Martínez, J. J., Pablos, J. L. M.-D., Figueras, M., Galera, J., & Serra, A. (2005) · Journal of Hypertension · doi:10.1097/01.hjh.0000198023.53859.a2 · Cited by 159 · see citing works
Bonilla, P. I., Sánchez, E. M., Peralta, J. L., Oquendo, M. A. I., Alcalá, F. V., & Domínguez, A. C. (2002) · Atención Primaria · doi:10.1016/s0212-6567(02)78959-2 · Cited by 27 · see citing works
Adverse events of blood-pressure-lowering drugs: evidence of high incidence in a clinical setting
Gonçalves, C. B. C., Moreira, L. B., Gus, M., & Fuchs, F. D. (2007) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-007-0352-y · Cited by 24 · see citing works
Self-citationNoncardiovascular Illness as Barrier to Antihypertensive Treatment
Staessen, J. A., Thijs, L., & Birkenhäger, W. H. (2005) · Hypertension · doi:10.1161/01.hyp.0000172754.53463.38 · Cited by 9 · see citing works
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Uhlig, K., Patel, K., Ip, S., Kitsios, G. D., & Balk, E. M. (2013) · Annals of Internal Medicine · doi:10.7326/0003-4819-159-3-201308060-00008 · Cited by 368 · see citing works
Satoh, M., Maeda, T., Hoshide, S., & Ohkubo, T. (2019) · Hypertension Research · doi:10.1038/s41440-019-0221-y · Cited by 28 · see citing works
Satoh, M., Tatsumi, Y., Nakayama, S., Shinohara, Y., Kawazoe, M., Nozato, Y., Kunimura, A., Murakami, T., Toyama, M., Muroya, T., et al. (2025) · Hypertension Research · doi:10.1038/s41440-024-01981-4 · Cited by 25 · see citing works
David, C. N., Iochpe, C., Harzheim, E., Sesin, G. P., Gonçalves, M. R., Moreira, L. B., Fuchs, F. D., & Fuchs, S. C. (2023) · Healthcare · doi:10.3390/healthcare11081069 · Cited by 11 · see citing works
“Given the ever-increasing number of smartphone users worldwide [14], mHealth interventions have the potential to not only control BP, but also foster significant lifestyle modifications [15].”
BackgroundSelf-citationCuffee, Y. L., Sciamanna, C., Gerin, W., Lehman, E., Cover, L., Johnson, A. A., Pool, A., & Yang, C. (2019) · American Journal of Hypertension · doi:10.1093/ajh/hpy160 · Cited by 11 · see citing works
Grover, S., Mishra, H. P., Gupta, R., & Gupta, L. K. (2025) · Journal of Hypertension · doi:10.1097/hjh.0000000000004008 · Cited by 8 · see citing works
Fuchs, S. C., Harzheim, E., Iochpe, C., David, C. N. D., Gonçalves, M. R., Sesin, G. P., Costa, C. M., Moreira, L. B., & Fuchs, F. D. (2018) · JMIR Research Protocols · doi:10.2196/resprot.9619 · Cited by 4 · see citing works
Self-citation
- Authors
- Fuchs, S. C., Ferreira-da-silva, A. L., Moreira, L. B., Neyeloff, J. L., Fuchs, F. C., Gus, M., Wiehe, M., & Fuchs, F. D.
- Affiliations
- Universidade Federal do Rio Grande do Sul (BR)
- Conselho Nacional de Desenvolvimento Científico e Tecnológico (BR)
- Hospital de Clínicas de Porto Alegre (BR)
- Corresponding author
- Fuchs, Sandra C.
- Fuchs, Felipe C.
- Fuchs, Flávio D.
- Venue
- Journal of Hypertension
- Published
- 2012-01
- Volume
- 30
- Issue
- 1
- Pages
- 75-80
- ISSN
- 0263-6352 (ISSN-L)
- OpenAlex
- W2322061283
- Cited by
- 36
- References
- 17
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 4 · 2023: 3 · 2022: 1 · 2021: 1 · 2020: 2 · 2019: 3 · 2018: 4 · 2017: 2 · 2016: 1 · 2015: 4 · 2014: 2 · 2013: 6 · 2012: 1
- FWCI
- 1.98
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Hypertension (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Nursing › Nutrition and Dietetics › Sodium Intake and Health
- Keywords
- home blood pressure monitoring, hypertension, blood pressure control, ambulatory blood pressure monitoring, medication adherence, antihypertensive therapy, uncontrolled hypertension, systolic blood pressure, diastolic blood pressure
- MeSH terms
- Blood Pressure, Humans, Outcome Assessment, Health Care, Blood Pressure Monitoring, Ambulatory
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