Skeletal muscle as a gene regulatory endocrine organ

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

Boström, P., Wu, J., Jedrychowski, M. P., Korde, A., Ye, L., Lo, J. C., Rasbach, K. A., Boström, E. A., Choi, J. H., Long, J. Z., et al. (2012) · Nature · doi:10.1038/nature10777 · Cited by 4,810 · see citing works

Exercise as medicine - evidence for prescribing exercise as therapy in 26 different chronic diseases

Pedersen, B. K., & Saltin, B. (2015) · Scandinavian Journal of Medicine & Science in Sports · doi:10.1111/sms.12581 · Cited by 3,514 · see citing works

Voluntary running suppresses tumor growth through epinephrine- and IL-6-dependent NK cell mobilization and redistribution

Pedersen, L., Idorn, M., Olofsson, G. H., Lauenborg, B., Nookaew, I., Hansen, R. H., Johannesen, H. H., Becker, J. C., Pedersen, K. S., Dethlefsen, C., et al. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2016.01.011 · Cited by 888 · see citing works

Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin

Mauer, J., Chaurasia, B., Goldau, J., Vogt, M. C., Ruud, J., Nguyen, K. D., Theurich, S., Hausen, A. C., Schmitz, J., Brönneke, H. S., et al. (2014) · Nature Immunology · doi:10.1038/ni.2865 · Cited by 727 · see citing works

Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry

Jedrychowski, M. P., Wrann, C. D., Paulo, J. A., Gerber, K. K., Szpyt, J., Robinson, M. M., Nair, K. S., Gygi, S. P., & Spiegelman, B. M. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.08.001 · Cited by 568 · see citing works

Exercise as an anti-inflammatory therapy for rheumatic diseases—Myokine regulation

Benatti, F. B., & Pedersen, B. K. (2015) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2014.193 · Cited by 474 · see citing works

Skeletal muscle as an endocrine organ: PGC-1α, myokines and exercise

Schnyder, S., & Handschin, C. (2015) · Bone · doi:10.1016/j.bone.2015.02.008 · Cited by 419 · see citing works

Versatile functions for IL-6 in metabolism and cancer

Mauer, J., Denson, J. L., & Brüning, J. C. (2015) · Trends in Immunology · doi:10.1016/j.it.2014.12.008 · Cited by 405 · see citing works

The role of intratumoral and systemic IL-6 in breast cancer

Dethlefsen, C., Højfeldt, G. W., & Højman, P. (2013) · Breast Cancer Research and Treatment · doi:10.1007/s10549-013-2488-z · Cited by 363 · see citing works

Irisin – a myth rather than an exercise-inducible myokine

Albrecht, E., Norheim, F., Thiede, B., Holen, T., Ohashi, T., Schering, L., Lee-Ødegård, S., Brenmoehl, J., Thomas, S., Drevon, C. A., et al. (2015) · Scientific Reports · doi:10.1038/srep08889 · Cited by 346 · see citing works

IL-6 biology: implications for clinical targeting in rheumatic disease

Calabrese, L., & Rose-John, S. (2014) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2014.127 · Cited by 329 · see citing works

Evidence against a Beneficial Effect of Irisin in Humans

Raschke, S., Elsen, M., Gassenhuber, J., Sommerfeld, M. R., Schwahn, U., Brockmann, B., Jung, R., Wisløff, U., Tjønna, A. E., Raastad, T., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0073680 · Cited by 318 · see citing works

Exercise and type 2 diabetes: focus on metabolism and inflammation

Karstoft, K., & Pedersen, B. K. (2016) · Immunology & Cell Biology · doi:10.1038/icb.2015.101 · Cited by 260 · see citing works

Blocking IL-6 trans-signaling prevents high-fat diet-induced adipose tissue macrophage recruitment but does not improve insulin resistance

Kraakman, M. J., Kammoun, H. L., Allen, T. L., Deswaerte, V., Henstridge, D. C., Estevez, E., Matthews, V. B., Neill, B., White, D. A., Murphy, A. J., et al. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.02.006 · Cited by 257 · see citing works

The myokine decorin is regulated by contraction and involved in muscle hypertrophy

Kanzleiter, T., Rath, M., Görgens, S. W., Jensen, J., Tangen, D. S., Kolnes, A. J., Kolnes, K. J., Lee, S., Eckel, J., Schürmann, A., et al. (2014) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2014.06.123 · Cited by 209 · see citing works

Identification and Validation of Novel Contraction-Regulated Myokines Released from Primary Human Skeletal Muscle Cells

Raschke, S., Eckardt, K., Bjørklund Holven, K., Jensen, J., & Eckel, J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0062008 · Cited by 199 · see citing works

Exercise‐stimulated interleukin‐15 is controlled by<scp>AMPK</scp>and regulates skin metabolism and aging

Crane, J. D., MacNeil, L. G., Lally, J. S., Ford, R. J., Bujak, A. L., Brar, I. K., Kemp, B. E., Raha, S., Steinberg, G. R., & Tarnopolsky, M. A. (2015) · Aging Cell · doi:10.1111/acel.12341 · Cited by 179 · see citing works

The IL-1 Pathway in Type 2 Diabetes and Cardiovascular Complications

Herder, C., Dalmas, É., Böni‐Schnetzler, M., & Donath, M. Y. (2015) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2015.08.001 · Cited by 169 · see citing works

Secretome profiling of primary human skeletal muscle cells

Hartwig, S., Raschke, S., Knebel, B., Scheler, M., Irmler, M., Paßlack, W., Müller, S., Hanisch, F., Franz, T., Li, X., et al. (2013) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2013.08.004 · Cited by 168 · see citing works

Exercise increases pancreatic β‐cell viability in a model of type 1 diabetes through IL‐6 signaling

de Paula, F. M. M., Leite, N. C., Vanzela, E. C., Kurauti, M. A., Dias, R. D. F., Carneiro, E. M., Boschero, A. C., & Zoppi, C. C. (2015) · The FASEB Journal · doi:10.1096/fj.14-264820 · Cited by 78 · see citing works

Secretome Analysis of Lipid-Induced Insulin Resistance in Skeletal Muscle Cells by a Combined Experimental and Bioinformatics Workflow

Deshmukh, A. S., Cox, J., Jensen, L. J., Meissner, F., & Mann, M. (2015) · Journal of Proteome Research · doi:10.1021/acs.jproteome.5b00720 · Cited by 67 · see citing works

The secretome of the working human skeletal muscle—A promising opportunity to combat the metabolic disaster?

Weigert, C., Lehmann, R., Hartwig, S., & Lehr, S. (2013) · PROTEOMICS - CLINICAL APPLICATIONS · doi:10.1002/prca.201300094 · Cited by 57 · see citing works

The role of gp130 receptor cytokines in the regulation of metabolic homeostasis

Cron, L., Allen, T. L., & Febbraio, M. A. (2016) · Journal of Experimental Biology · doi:10.1242/jeb.129213 · Cited by 53 · see citing works

Muscle-Derived IL-6 Is Not Regulated by IL-1 during Exercise. A Double Blind, Placebo-Controlled, Randomized Crossover Study

Nordmann, T. M., Seelig, E., Timper, K., Cordes, M., Coslovsky, M., Hanssen, H., Schmidt‐Trucksäss, A., & Donath, M. Y. (2015) · PLoS ONE · doi:10.1371/journal.pone.0139662 · Cited by 10 · see citing works

Muscle–Organ Crosstalk: The Emerging Roles of Myokines

Severinsen, M. C. K., & Pedersen, B. K. (2020) · Endocrine Reviews · doi:10.1210/endrev/bnaa016 · Cited by 1,226 · see citing works

Physical activity and muscle-brain crosstalk

Pedersen, B. K. (2019) · Nature Reviews Endocrinology · doi:10.1038/s41574-019-0174-x · Cited by 772 · see citing works

Role of Inactivity in Chronic Diseases: Evolutionary Insight and Pathophysiological Mechanisms

Booth, F. W., Roberts, C. K., Thyfault, J. P., Ruegsegger, G. N., & Toedebusch, R. G. (2017) · Physiological Reviews · doi:10.1152/physrev.00019.2016 · Cited by 696 · see citing works

Aerobic vs. resistance exercise in non-alcoholic fatty liver disease: a systematic review

Hashida, R., Kawaguchi, T., Bekki, M., Omoto, M., Matsuse, H., Nago, T., Takano, Y., Ueno, T., Koga, H., George, J., et al. (2017) · Journal of Hepatology · doi:10.1016/j.jhep.2016.08.023 · Cited by 509 · see citing works

Exercise and metabolic health: beyond skeletal muscle

Thyfault, J. P., & Bergouignan, A. (2020) · Diabetologia · doi:10.1007/s00125-020-05177-6 · Cited by 436 · see citing works

Physical Exercise-Induced Myokines and Muscle-Adipose Tissue Crosstalk: A Review of Current Knowledge and the Implications for Health and Metabolic Diseases

Leal, L. G., Lopes, M. A., & Batista, M. L. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01307 · Cited by 382 · see citing works

Physical inactivity: a risk factor and target for intervention in renal care

Zelle, D. M., Klaassen, G., van Adrichem, E. J., Bakker, S. J. L., Corpeleijn, E., & Navis, G. J. (2017) · Nature Reviews Nephrology · doi:10.1038/nrneph.2016.187 · Cited by 284 · see citing works

The molecular athlete: exercise physiology from mechanisms to medals

Furrer, R., Hawley, J. A., & Handschin, C. (2023) · Physiological Reviews · doi:10.1152/physrev.00017.2022 · Cited by 232 · see citing works

Signaling Pathways That Control Muscle Mass

Vainshtein, A., & Sandri, M. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21134759 · Cited by 214 · see citing works

The role of omega-3 in the prevention and treatment of sarcopenia

Dupont, J., Dedeyne, L., Dalle, S., Koppo, K., & Gielen, E. (2019) · Aging Clinical and Experimental Research · doi:10.1007/s40520-019-01146-1 · Cited by 208 · see citing works

Myonectin Is an Exercise-Induced Myokine That Protects the Heart From Ischemia-Reperfusion Injury

Otaka, N., Shibata, R., Ohashi, K., Uemura, Y., Kambara, T., Enomoto, T., Ogawa, H., Ito, M., Kawanishi, H., Maruyama, S., et al. (2018) · Circulation Research · doi:10.1161/circresaha.118.313777 · Cited by 189 · see citing works

Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice

Castaño, C., Mirasierra, M., Vallejo, M., Novials, A., & Párrizas, M. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2016112117 · Cited by 154 · see citing works

Growth and differentiation factor 15 is secreted by skeletal muscle during exercise and promotes lipolysis in humans

Laurens, C., Parmar, A., Murphy, E., Carper, D., Lair, B., Maes, P., Vion, J., Boulet, N., Fontaine, C., Marquès, M., et al. (2020) · JCI Insight · doi:10.1172/jci.insight.131870 · Cited by 135 · see citing works

The kynurenine connection: how exercise shifts muscle tryptophan metabolism and affects energy homeostasis, the immune system, and the brain

Martin, K. S., Azzolini, M., & Ruas, J. L. (2020) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00580.2019 · Cited by 126 · see citing works

Myokines in skeletal muscle physiology and metabolism: Recent advances and future perspectives

Das, D. K., Graham, Z. A., & Cardozo, C. P. (2020) · Acta Physiologica · doi:10.1111/apha.13367 · Cited by 129 · see citing works

The NAD World 2.0: the importance of the inter-tissue communication mediated by NAMPT/NAD+/SIRT1 in mammalian aging and longevity control

Imai, S. (2016) · npj Systems Biology and Applications · doi:10.1038/npjsba.2016.18 · Cited by 99 · see citing works

Irisin reverses the IL-6 induced epithelial-mesenchymal transition in osteosarcoma cell migration and invasion through the STAT3/Snail signaling pathway

Kong, G., Jiang, Y., Sun, X., Cao, Z., Zhang, G., Zhao, Z., Zhao, Y. B., Qian, Y., & Cheng, G. (2017) · Oncology Reports · doi:10.3892/or.2017.5973 · Cited by 96 · see citing works

Organ crosstalk and dysfunction in sepsis

Borges, A., & Bento, L. F. N. (2024) · Annals of Intensive Care · doi:10.1186/s13613-024-01377-0 · Cited by 93 · see citing works

CT of Patients With Hip Fracture: Muscle Size and Attenuation Help Predict Mortality

Boutin, R. D., Bamrungchart, S., Bateni, C. P., Beavers, D. P., Beavers, K. M., Meehan, J. P., & Lenchik, L. (2017) · American Journal of Roentgenology · doi:10.2214/ajr.16.17226 · Cited by 94 · see citing works

Association of muscle wasting with mortality risk among adults: A systematic review and meta‐analysis of prospective studies

Zhou, H., Liao, Y., Peng, Z., Liu, F., Wang, Q., & Yang, W. Q. (2023) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.13263 · Cited by 72 · see citing works

The value of interleukin 6 as a peripheral diagnostic marker in schizophrenia

Chase, K. A., Cone, J. J., Rosen, C., & Sharma, R. P. (2016) · BMC Psychiatry · doi:10.1186/s12888-016-0866-x · Cited by 69 · see citing works

Diet and physical exercise as key players to tackle MASLD through improvement of insulin resistance and metabolic flexibility

Mambrini, S. P., Grillo, A., Colosimo, S., Zarpellon, F., Pozzi, G., Furlan, D., Amodeo, G., & Bertoli, S. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1426551 · Cited by 70 · see citing works

Sustained elevation of MG53 in the bloodstream increases tissue regenerative capacity without compromising metabolic function

Bian, Z., Wang, Q., Zhou, X., Tan, T., Park, K. H., Kramer, H. F., McDougal, A. V., Laping, N. J., Kumar, S., Adesanya, T. M. A., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-12483-0 · Cited by 68 · see citing works

The effects of myosteatosis on skeletal muscle function in older adults

Dondero, K., Friedman, B., Rekant, J., Landers‐Ramos, R., & Addison, O. (2024) · Physiological Reports · doi:10.14814/phy2.16042 · Cited by 63 · see citing works

Metabolic Syndrome in Children and Adolescents

Gräf, C., & Ferrari, N. (2016) · Visceral Medicine · doi:10.1159/000449268 · Cited by 61 · see citing works

Irisin and Autophagy: First Update

Pesce, M., Ballerini, P., Paolucci, T., Puca, I., Farzaei, M. H., & Patruno, A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21207587 · Cited by 59 · see citing works

Icariin induces irisin/FNDC5 expression in C2C12 cells via the AMPK pathway

Chen, S., Ding, L., Zeng, N.-X., Liu, H., Zheng, S., Xu, J.-W., & Li, R. (2019) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2019.108930 · Cited by 50 · see citing works

Role of interleukin‐15 in cardiovascular diseases

Guo, L., Liu, M.-F., Huang, J., Li, J., Jiang, J., & Wang, J. (2020) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.15296 · Cited by 47 · see citing works

Dose–response effects of physical activity on all-cause mortality and major cardiorenal outcomes in chronic kidney disease

Kuo, C.-P., Tsai, M., Lee, K., Lin, Y., Huang, S., Huang, C., Tseng, W., & Tarng, D. (2021) · European Journal of Preventive Cardiology · doi:10.1093/eurjpc/zwaa162 · Cited by 47 · see citing works

Body Protein Sparing in Hibernators: A Source for Biomedical Innovation

Bertile, F., Habold, C., Maho, Y. L., & Giroud, S. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.634953 · Cited by 46 · see citing works

β-aminoisobutyric acid protects against vascular inflammation through PGC-1β-induced antioxidative properties

Sawada, M., Yamamoto, H., Ogasahara, A., Tanaka, Y., & Kihara, S. (2019) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2019.06.141 · Cited by 44 · see citing works

An Exercise-Induced Metabolic Shield in Distant Organs Blocks Cancer Progression and Metastatic Dissemination

Sheinboim, D., Parikh, S., Manich, P., Markus, I., Dahan, S., Parikh, R., Stubbs, E., Cohen, G., Zemser‐Werner, V., Bell, R. E., et al. (2022) · Cancer Research · doi:10.1158/0008-5472.can-22-0237 · Cited by 44 · see citing works

Chrono-exercise: Time-of-day-dependent physiological responses to exercise

Kim, H., Radak, Z. O., Takahashi, M., Inami, T., & Shibata, S. (2022) · Sports Medicine and Health Science · doi:10.1016/j.smhs.2022.11.003 · Cited by 46 · see citing works

Time-course effects of aerobic physical training in the prevention of cigarette smoke-induced COPD

de Toledo, A. C., Vieira, R. P., Guarnier, F. A., Suehiro, C. L., Caleman-Neto, A., Olivo, C. R., Arantes, P. M. M., de Almeida, F. M., Lopes, F. D. T. Q. D. S., Ramos, E. M. C., et al. (2017) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00819.2016 · Cited by 43 · see citing works

A focused review of myokines as a potential contributor to muscle hypertrophy from resistance-based exercise

Cornish, S. M., Bugera, E. M., Duhamel, T. A., Peeler, J. D., & Anderson, J. E. (2020) · European Journal of Applied Physiology · doi:10.1007/s00421-020-04337-1 · Cited by 43 · see citing works

Psoralea corylifolia L. seed extract attenuates dexamethasone-induced muscle atrophy in mice by inhibition of oxidative stress and inflammation

Seo, E., Truong, C.-S., & Jun, H. (2022) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2022.115490 · Cited by 42 · see citing works

Irisin enhances longevity by boosting SIRT1, AMPK, autophagy and telomerase

Sánchez, B., Muñoz-Pinto, M. F., & Cano, M. (2023) · Expert Reviews in Molecular Medicine · doi:10.1017/erm.2022.41 · Cited by 38 · see citing works

Intensity Dependent Effects of Interval Resistance Training on Myokines and Cardiovascular Risk Factors in Males With Obesity

Ataeinosrat, A., Saeidi, A., Abednatanzi, H., Rahmani, H., Daloii, A. A., Pashaei, Z., Hojati, V., Basati, G., Mossayebi, A., Laher, I., et al. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.895512 · Cited by 40 · see citing works

Muscle-Derived Cytokines Reduce Growth, Viability and Migratory Activity of Pancreatic Cancer Cells

Schwappacher, R., Dieterich, W., Reljic, D., Pilarsky, C. P., Mukhopadhyay, D., Chang, D. K.-F., Biankin, A. V., Siebler, J., Herrmann, H. J., Neurath, M. F., et al. (2021) · Cancers · doi:10.3390/cancers13153820 · Cited by 39 · see citing works

Exercise-induced myokines: a brief review of controversial issues of this decade

Son, J. S., Chae, S. A., Testroet, E. D., Du, ‬., & Jun, H.-P. (2017) · Expert Review of Endocrinology & Metabolism · doi:10.1080/17446651.2018.1416290 · Cited by 38 · see citing works

Testosterone insulin-like effects: an in vitro study on the short-term metabolic effects of testosterone in human skeletal muscle cells

Antinozzi, C., Marampon, F., Corinaldesi, C., Vicini, E., Sgrò, P., Vannelli, G. B., Lenzi, A., Crescioli, C., & Luigi, L. D. (2017) · Journal of Endocrinological Investigation · doi:10.1007/s40618-017-0686-y · Cited by 37 · see citing works

The Prognostic Value of Low Muscle Mass in Pancreatic Cancer Patients: A Systematic Review and Meta-Analysis

Pierobon, E. S., Moletta, L., Zampieri, S., Sartori, R., Brazzale, A. R., Zanchettin, G., Serafini, S., Capovilla, G., Valmasoni, M., Merigliano, S., et al. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10143033 · Cited by 37 · see citing works

Gene therapy for genetic diseases: challenges and future directions

Beibei, Q. I. E., Tuo, J., Chen, F., Ding, H., & Lyu, L. (2025) · MedComm · doi:10.1002/mco2.70091 · Cited by 37 · see citing works

Brief exposure to directionally-specific pulsed electromagnetic fields stimulates extracellular vesicle release and is antagonized by streptomycin: A potential regenerative medicine and food industry paradigm

Wong, C. J. K., Tai, Y. K., Yap, J. L. Y., Fong, C. H. H., Loo, L. S. W., Kukumberg, M., Fröhlich, J., Zhang, S., Li, J., Wang, J., et al. (2022) · Biomaterials · doi:10.1016/j.biomaterials.2022.121658 · Cited by 35 · see citing works

Skeletal muscle secretome in Duchenne muscular dystrophy: A pivotal anti-inflammatory role of adiponectin

Lecompte, S., Abou-Samra, M., Boursereau, R., Noel, L., & Brichard, S. M. (2017) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-017-2465-5 · Cited by 34 · see citing works

Modified creatinine index and risk for long-term infection-related mortality in hemodialysis patients: ten-year outcomes of the Q-Cohort Study

Arase, H., Yamada, S., Hiyamuta, H., Taniguchi, M., Tokumoto, M., Tsuruya, K., Nakano, T., & Kitazono, T. (2020) · Scientific Reports · doi:10.1038/s41598-020-58181-6 · Cited by 34 · see citing works

Physical activity and advanced cancer: evidence of exercise‐sensitive genes regulating prostate cancer cell proliferation and apoptosis

Schwappacher, R., Schink, K., Sologub, S., Dieterich, W., Reljic, D., Friedrich, O., Herrmann, H. J., Neurath, M. F., & Zopf, Y. (2020) · The Journal of Physiology · doi:10.1113/jp279150 · Cited by 33 · see citing works

Myokine, a key cytokine for physical exercise to alleviate sarcopenic obesity

Zhang, L., Lv, J., Wang, C., Ren, Y., & Ming, Y. (2022) · Molecular Biology Reports · doi:10.1007/s11033-022-07821-3 · Cited by 32 · see citing works

Endurance exercise protects skeletal muscle against both doxorubicin-induced and inactivity-induced muscle wasting

Powers, S. K., Duarte, J. A., Nguyen, B. L., & Hyatt, H. W. (2018) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-018-2227-8 · Cited by 30 · see citing works

Diurnal Regulation of Peripheral Glucose Metabolism: Potential Effects of Exercise Timing

Mancilla, R., Krook, A., Schrauwen, P., & Hesselink, M. K. C. (2020) · Obesity · doi:10.1002/oby.22811 · Cited by 29 · see citing works

Sarcopenia: A dive into metabolism to promote a multimodal, preventive, and regenerative approach

Boccardi, V. (2024) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2024.111941 · Cited by 29 · see citing works

Obesity Management in the Primary Prevention of Hepatocellular Carcinoma

Zunica, E. R. M., Heintz, E. C., Axelrod, C. L., & Kirwan, J. P. (2022) · Cancers · doi:10.3390/cancers14164051 · Cited by 30 · see citing works

Brief, weekly magnetic muscle therapy improves mobility and lean body mass in older adults: a Southeast Asia community case study

Venugobal, S., Tai, Y. K., Goh, J., Teh, S. W., Wong, C. J. K., Goh, I., Maier, A. B., Kennedy, B. K., & Franco‐Obregón, A. (2023) · Aging · doi:10.18632/aging.204597 · Cited by 28 · see citing works

Exercise Inhibits the Effects of Smoke‐Induced COPD Involving Modulation of STAT3

Brandão-Rangel, M. A. R., Bachi, A. L. L., Oliveira‐Junior, M. C., Abbasi, A., Silva-Rennó, A., de Brito, A. A., de Oliveira, A. P. L., de Toledo, A. C., Belvisi, M. G., & Vieira, R. P. (2017) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2017/6572714 · Cited by 28 · see citing works

Are inflammatory markers associated with sarcopenia-related traits in older adults with sarcopenia? – A cross-sectional analysis of the ENHANce study

Dupont, J., Vercauteren, L., Amini, N., Lapauw, L., Schaepdryver, M. D., Poesen, K., Dedeyne, L., Verschueren, S., Tournoy, J., Koppo, K., et al. (2023) · Experimental Gerontology · doi:10.1016/j.exger.2023.112196 · Cited by 27 · see citing works

Cardioprotective Exercise and Pharmacologic Interventions as Complementary Antidotes to Cardiovascular Disease

Quindry, J. C., & Franklin, B. A. (2017) · Exercise and Sport Sciences Reviews · doi:10.1249/jes.0000000000000134 · Cited by 27 · see citing works

Low serum creatinine predicts risk for type 2 diabetes

Bao, X., Gu, Y., Zhang, Q., Liu, L., Meng, G., Wu, H., Xia, Y., Shi, H., Wang, H., Sun, S., et al. (2018) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.3011 · Cited by 26 · see citing works

The diagnostic and prognostic roles of serum irisin in bladder cancer

Esawy, M. M., & Abdel-Samd, K. M. (2019) · Current Problems in Cancer · doi:10.1016/j.currproblcancer.2019.100529 · Cited by 26 · see citing works

Effects of the exercise-inducible myokine irisin on proliferation and malignant properties of ovarian cancer cells through the HIF-1 α signaling pathway

Zarei, M. A., Hosseini, E. S., Kashani, H. H., Ahmad, E., Aslanbeigi, F., & Nikzad, H. (2023) · Scientific Reports · doi:10.1038/s41598-022-26700-2 · Cited by 25 · see citing works

Human Body Composition and Muscle Mass

Duda, K., Majerczak, J., Nieckarz, Z., Heymsfield, S. B., & Zoladz, J. A. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-814593-7.00001-3 · Cited by 23 · see citing works

Causal associations of obesity related anthropometric indicators and body compositions with knee and hip arthritis: A large-scale genetic correlation study

Wang, C., Zhu, Y., Liu, Z., Long, H., Ruan, Z., & Zhao, S. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.1011896 · Cited by 23 · see citing works

Treatment with EV-miRNAs Alleviates Obesity-Associated Metabolic Dysfunction in Mice

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Association of metabolic traits with occurrence of nonalcoholic fatty liver disease-related hepatocellular carcinoma

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The Developmental Implications of Muscle-Targeted Magnetic Mitohormesis: A Human Health and Longevity Perspective

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C/EBPβ mediates palmitate-induced musclin expression via the regulation of PERK/ATF4 pathways in myotubes

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FNDC5 polymorphism influences the association between sarcopenia and liver fibrosis in adults with biopsy-proven non-alcoholic fatty liver disease

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DNA Methylation Reorganization of Skeletal Muscle-Specific Genes in Response to Gestational Obesity

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Impact of diets rich in olive oil, palm oil or lard on myokine expression in rats

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An Overview of Inter-Tissue and Inter-Kingdom Communication Mediated by Extracellular Vesicles in the Regulation of Mammalian Metabolism

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Mst1/2 Is Necessary for Satellite Cell Differentiation to Promote Muscle Regeneration

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Exerkines: A Crosstalk between Lactate Production, Exercise and Mental Health

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Effects of Exercise Intervention in Subjects with Metabolic Dysfunction-Associated Steatotic Liver Disease

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Multi-Cellular Functions of MG53 in Muscle Calcium Signaling and Regeneration

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Systemically Administered Homing Peptide Targets Dystrophic Lesions and Delivers Transforming Growth Factor-β (TGFβ) Inhibitor to Attenuate Murine Muscular Dystrophy Pathology

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Binge drinking leads to an oxidative and metabolic imbalance in skeletal muscle during adolescence in rats: endocrine repercussion

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The impact of supervised physical exercise on chemokines and cytokines in recovered COVID-19 patients

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Exercise and Organ Cross Talk

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Prognostic Impact of Sarcopenia in Patients With Biliary Tract Cancer Undergoing Chemotherapy

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Comparative efficacy of different exercise modalities on metabolic profiles and liver functions in non-alcoholic fatty liver disease: a network meta-analysis

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Sedentary lifestyle induces oxidative stress and atrophy in rat skeletal muscle

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Associations of CT Muscle Area and Density With Functional Outcomes and Mortality Across Anatomical Regions in Older Men

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Effects of MicroRNAs and Long Non-coding RNAs on Beneficial Action of Exercise on Cognition in Degenerative Diseases: A Review

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Skeletal Muscle

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BDA-410 Treatment Reduces Body Weight and Fat Content by Enhancing Lipolysis in Sedentary Senescent Mice

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Could Urinary Amino Acids be as New Biomarkers for Detection of Sarcopenia?

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Population Genetic Polymorphism of Skeletal Muscle Strength Related Genes in Five Ethnic Minorities in North China

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Brief Weekly Magnetic Field Exposure Enhances Avian Oxidative Muscle Character During Embryonic Development

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Mood, Cognitive Function, and Plasma Kynurenine Metabolites Responses Following Severe Changes in Physical Activity

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Myokines related to leukocyte recruitment are down-regulated in osteosarcoma

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The role of vitamin D3 in ameliorating LPS-induced flesh quality depress in grass carp (Ctenopharyngodon idella): Insights into antioxidant capacity, collagen synthesis, and myofiber development

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Enhancing Post-Training Muscle Recovery and Strength in Paralympic Powerlifting Athletes with Cold-Water Immersion, a Cross-Sectional Study

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Puerarin Delays the Progression of Muscle Atrophy in Mice With Dexamethasone‐Induced Sarcopenia Through Inhibiting the TNF‐α/NF‐κB Pathway

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The effect of eight weeks of aerobic exercise with moderate and high intensities on serum irisin and PGC-1α protein levels in obese male Wistar rats

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Local and systemic transcriptomic responses from acute exercise induced muscle damage of the human knee extensors

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Annexin A2 Causes Motor Incoordination via Muscle–Cerebellum Axis in Sarcopenia

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Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6

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Exercise-induced myokines in metabolic regulation: mechanisms, mimetics, and translational potential

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Skeletal Muscle, Myokines and Health

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Edward F. Adolph Distinguished Lecture: Muscle as an endocrine organ: IL-6 and other myokines

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