Cited by 268Stress Responses and CortisolChild Abuse and TraumaResilience and Mental Health

The DOI matches its Crossref record; 54 of the 55 references it cites were found in a registry or an index; none of the 19 sources its claims cite is checked for support yet.

Assessing Lifetime Stress Exposure Using the Stress and Adversity Inventory for Adults (Adult STRAIN): An Overview and Initial Validation

Open access
Slavich, George M., Shields, Grant S.·2018·Psychosomatic Medicine

Abstract

Objective: Numerous theories have proposed that acute and chronic stressors may exert a cumulative effect on life-span health by causing biological “wear and tear,” or allostatic load, which in turn promotes disease. Very few studies have directly tested such models, though, partly because of the challenges associated with efficiently assessing stress exposure over the entire life course. To address this issue, we developed the first online system for systematically assessing lifetime stress exposure, called the Stress and Adversity Inventory (STRAIN), and describe its initial validation here. Methods: Adults recruited from the community (n = 205) were administered the STRAIN, Childhood Trauma Questionnaire—Short Form, and Perceived Stress Scale, as well as measures of socioeconomic status, personality, social desirability, negative affect, mental and physical health complaints, sleep quality, computer-assessed executive function, and doctor-diagnosed general health problems and autoimmune disorders. Results: The STRAIN achieved high acceptability and was completed relatively quickly (mean = 18 minutes 39 seconds; interquartile range = 12–23 minutes). The structure of the lifetime stress data best fit two latent classes overall and five distinct trajectories over time. Concurrent associations with the Childhood Trauma Questionnaire—Short Form and Perceived Stress Scale were good (r values = .147–.552). Moreover, the STRAIN was not significantly related to personality traits or social desirability characteristics and, in adjusted analyses, emerged as the measure most strongly associated with all six of the health and cognitive outcomes assessed except current mental health complaints (β values = .16–.41; risk ratios = 1.02–1.04). Finally, test-retest reliability for the main stress exposure indices over 2–4 weeks was excellent (r values = .904–.919). Conclusions: The STRAIN demonstrated good usability and acceptability; very good concurrent, discriminant, and predictive validity; and excellent test-retest reliability.

Overview

AI snapshot

Written from the paper’s full text.

TL;DR

The Adult STRAIN is a self- or interviewer-administered online measure of lifetime stress exposure that showed high usability, excellent test-retest reliability, and good concurrent, discriminant, and predictive validity in a community sample of 205 adults. It predicted six health/cognitive outcomes and generally outperformed the CTQ-SF and PSS, though the study was largely cross-sectional and the sample was not racially diverse.

Key findings

  • Participants completed the STRAIN in an average of 18 minutes 39 seconds; completion rate was 90.8% among 369 who began, and negative affect did not change from pre- to post-STRAIN (M = 1.65 vs. 1.67, p = .341, d = 0.03).
  • Participants reported an average of 25.77 lifetime stressors (SD = 16.85; range 1–83) and an average overall severity score of 63.26 (SD = 37.73). Latent class analysis found two groups: low-stress (n = 116; M = 13.90 stressors) and high-stress (n = 89; M = 41.25 stressors); latent trajectory analysis found five trajectories.
  • Concurrent validity: lifetime stressor count correlated with CTQ-SF (r = .552, p < .001) and PSS (r = .147, p = .035). Discriminant validity: it was not significantly associated with Big Five traits or social desirability (p values ≥ .08), whereas the PSS correlated with all five Big Five traits (|r| ≥ .17).
  • Predictive validity: lifetime stressor count predicted self-reported current health complaints (r = .321 and r = .469), worse sleep quality (r = .493), poorer executive function (r = .185), more doctor-diagnosed general health problems (RR = 1.026, 95% CI = 1.019–1.034), and more doctor-diagnosed autoimmune disorders (RR = 1.034, 95% CI = 1.017–1.051). Test-retest reliability over about 2 weeks was r = .919 for total lifetime stressor count and r = .904 for total severity; all main indices had r ≥ .873.

Methods

  • Community-based online sample of 205 adults (96 men, 107 women, 2 transgender; mean age = 37.82 years, SD = 11.72, range 19–68; 85.4% white). A randomly selected 100 participants completed the STRAIN again after a median of 13 days (range 9–36) for test-retest reliability, with 100% compliance.
  • Lifetime stress exposure was assessed with the Adult STRAIN, which enquires about 55 stressors (26 acute life events, 29 chronic difficulties) across 2 stressor types, 12 life domains, and 5 social-psychological characteristics. Other measures included the CTQ-SF, PSS, Ten Item Personality Inventory, Social Desirability Scale, PANAS negative affect, Stroop task, PSQI, K-6, PHQ, and doctor-diagnosed general health and autoimmune conditions.
  • Analyses used R 3.2.5; correlations and linear models for continuous outcomes, generalized linear models for count outcomes, latent class analysis with mclust (1–9 Gaussian clusters, BIC-selected), and latent trajectory analysis with flexmix using a quintic polynomial.

Limitations

  • Stated by the paper: the design was largely cross-sectional except for the test-retest portion, so causation cannot be assumed; STRAIN scores are self-reported and could still be influenced by unmeasured reporting biases or by recently occurring stressors; no biological samples were collected; and the sample was not particularly diverse with respect to race or ethnicity.
  • Stated by the paper: future work should test longer test-retest intervals, larger and more diverse samples, different cultures and languages, comparison with interview-based expert-rated measures, and predictive validity against biological and clinical outcomes less susceptible to self-report bias.
  • Evident from the text: the sample was a convenience online sample with a high attention-check failure/dropout rate before the final 205 were retained (45.7% of respondents), which may further limit generalizability beyond the stated racial/ethnic diversity concern.

Model-written summary. Check it against the paper before relying on it.

Integrity signals

Registry

Crossref · 10.1097/psy.0000000000000534

Cites

54 of 54 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

0 of 19 cited sources checked · 0 supported · 0 flagged

Show all 66 claims

  • It may state two separate claims as one. 21
  • Probably not a substantial claim. 14
  • The quote only partly states this claim. 1
35 of 35
  • The paper relies on this without support.

    The STRAIN's lifetime stressor count provides an objective measure of stress exposure.

    “permitting researchers to assess individuals' “objective” stress exposure (i.e., their lifetime stressor count) as well as their “subjective” stress experience (i.e., their lifetime stressor severity).”
  • The paper relies on this without support.

    The STRAIN's 55 stressors comprehensively cover all acute life events and chronic difficulties an individual may experience over the life course.

    “assessing all of the acute life events and chronic difficulties that an individual has experienced over his or her life course (51).”
  • The paper relies on this without support.

    Participants' retrospective reports of lifetime stressors are accurate enough to yield valid measures of lifetime stress exposure.

    “scores on the STRAIN are based on participants' reports”
    “self-reporting biases could still have influenced the results in unmeasured ways”
3 of 3

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Statistics recomputed

Every reported test result, recomputed from its test statistic and degrees of freedom. A result shows as not adding up only once an independent check has confirmed it.

  • Consistentt(204) = 25.78reported p < .001 · recomputed p < .001

    “t(204) = 25.78, p < .001”

  • Consistentt(170) = -0.96reported p = .341 · recomputed p = .338

    “t(170) = −0.96, p = .341”

  • ConsistentF(2, 202) = 5.05reported p = .007 · recomputed p = .007

    “F(2,202) = 5.05, p = .007”

  • ConsistentF(4, 199) = 0.54reported p = .708 · recomputed p = .707

    “F(4,199) = 0.54, p = .708”

4 of 4

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

Each contradiction between two passages listed here was confirmed by an independent check.

  • Physical health complaints are listed twice in place of mental health complaints

    Minor

    The results describe two correlations as being with physical health complaints, while the figure caption identifies physical and mental health complaints as separate outcomes.

1 of 1

Citations

Cites

Flagged first, then by citations

Show all 55 references

1 of the 55 references couldn’t be matched to a known paper.

Research works printed but not linked: 2

  1. 1980, Presidential address—1980. Psychosomatic and psychoimmunologic research, Psychosom Med, 42, 307
  2. 1996, Mental stress as a trigger of myocardial ischemia and infarction, Cardiol Clin, 14, 271

Cited by

Sorted by citations

See all 268

Metadata

Authors
Slavich, G. M., & Shields, G. S.
Affiliations
University of California, Los Angeles (US)
Corresponding author
Slavich, George M.
Venue
Psychosomatic Medicine
Published
2018-01
Volume
80
Issue
1
Pages
17-27
ISSN
  • 0033-3174 (ISSN-L)
  • 1534-7796
OpenAlex
W2923152359
Cited by
268
References
55
Citations by year
2026: 18 · 2025: 29 · 2024: 45 · 2023: 31 · 2022: 60 · 2021: 35 · 2020: 23 · 2019: 17 · 2018: 7
FWCI
7.29
Type
journal article
Language
en
Open access
Locations
  • Psychosomatic Medicine (publishedVersion, cc-by-nc-nd)
  • PubMed Central (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
Funders
National Institute of Mental Health (K08MH103443)
Topics
  • Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
  • Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
  • Social Sciences › Psychology › Clinical Psychology › Resilience and Mental Health
Keywords
allostatic load, cumulative stress, life course, stress trajectories, childhood trauma, perceived stress, online surveys, test-retest reliability, psychometric validation, health outcomes, autoimmune disease, sleep quality, executive function
MeSH terms
Adult Survivors of Child Adverse Events, Adult, Aged, Female, Humans, Male, Middle Aged, Psychiatric Status Rating Scales, Psychometrics, Stress, Psychological, Reproducibility of Results, Young Adult

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

A language model drew the claims from the paper on 2026-10-08, under version 3 of the claim definition (model deepseek-v4.1-flash, prompt extract-v3).

A second model labelled each claim on 2026-10-08 (model jev-1.13-20260917, definition revision gold-guideline-v0.2).

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review