The Impact of Pain and Depression on Recovery After Coronary Artery Bypass Grafting
Open accessAbstract
OBJECTIVE: To describe the relationship between pain and depression on recovery after coronary artery bypass grafting (CABG). METHODS: A secondary data analysis on 453 depressed and nondepressed post-CABG patients enrolled in a randomized, controlled, effectiveness trial of telephone-delivered collaborative care for depression. Outcome measures were collected from March 2004 to September 2007 and included pain, physical function, and mood symptoms. RESULTS: Depressed patients (baseline Patient Health Questionnaire-9 score ≥10) versus those without depression reported significantly worse pain scores on the 36-Item Short Form Health Survey Bodily Pain Scale at baseline and up to 12 months post-CABG, p < .05. Among patients with depression, those who received collaborative care reported significantly better pain scores at each time point between 2 and 12 months post-CABG versus depressed patients randomized to the usual care control group, p < .05. Regardless of intervention status, depressed participants with at least moderate pain at baseline reported significantly lower functional status (measured by the Duke Activity Status Index) at 8 and 12 months versus depressed patients with none or mild pain, p < .05. Depressed patients with at least moderate pain at baseline were also significantly less likely to show improvement of depressive symptoms throughout the course of follow-up versus depressed patients with little or no pain, p < .05. These findings controlled for age, gender, education, race, comorbid conditions, and baseline pain diagnosis. CONCLUSIONS: Depression and pain seem to influence functional recovery post-CABG. The relationship between these two conditions and 12-month outcomes should be considered by clinicians when planning treatment.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Unrealistic or unfulfilled expectations about surgery and preoperative stress may lead to higher levels of postoperative pain.
“In addition, realistic expectation management is key as unrealistic or unfulfilled expectations about surgery and preoperative stress may lead to the experience of higher levels of postoperative pain [12-18].”
From Benefits, Recruitment, Dropout, and Acceptability of the Strength Back Digital Health Intervention for Patients Undergoing Spinal Surgery: Nonrandomized, Qualitative, and Quantitative Pilot Feasibility Study (2024) · cites this paper as [17]
The Discussion (page not provided) links depression with pain after coronary artery bypass surgery, but says the relevant data were collected postoperatively. Searches for surgical expectations and preoperative stress found no passage addressing whether either leads to higher postoperative pain. (LLM, conf=0.76)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975) · Journal of Psychiatric Research · doi:10.1016/0022-3956(75)90026-6 · Cited by 88,282 · see citing works
The PHQ-9: Validity of a brief depression severity measure
Kroenke, K., Spitzer, R. L., & Williams, J. B. W. (2001) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2001.016009606.x · Cited by 44,910 · see citing works
(1992) · PubMed · Cited by 33,716 · see citing works
The MOS 36-ltem Short-Form Health Survey (SF-36): I. Conceptual Framework and Item Selection
Ware, J. E., & Sherbourne, C. D. (1992) · Medical Care · doi:10.1097/00005650-199206000-00002 · Cited by 30,033 · see citing works
Depression and Pain Comorbidity: A Literature Review
Bair, M. J., Robinson, R. L., Katon, W., & Kroenke, K. (2003) · Archives of Internal Medicine · doi:10.1001/archinte.163.20.2433 · Cited by 3,463 · see citing works
Hlatky, M. A., Boineau, R., Higginbotham, M. B., Lee, K. L., Mark, D. B., Califf, R. M., Cobb, F. R., & Pryor, D. B. (1989) · The American Journal of Cardiology · doi:10.1016/0002-9149(89)90496-7 · Cited by 1,745 · see citing works
The NIMH Epidemiologic Catchment Area Program
Regier, D. A. (1984) · Archives of General Psychiatry · doi:10.1001/archpsyc.1984.01790210016003 · Cited by 1,259 · see citing works
Depression as a risk factor for mortality after coronary artery bypass surgery
Blumenthal, J. A., Lett, H. S., Babyak, M. A., White, W., Smith, P. K., Mark, D. B., Jones, R., Mathew, J. P., & Newman, M. F. (2003) · The Lancet · doi:10.1016/s0140-6736(03)14190-6 · Cited by 662 · see citing works
Ranawat Award Paper: Predicting Total Knee Replacement Pain
Brander, V. A., Stulberg, S. D., Adams, A. D., Harden, R. N., Bruehl, S. P., Stanos, S. P., & Houle, T. T. (2003) · Clinical Orthopaedics and Related Research · doi:10.1097/01.blo.0000092983.12414.e9 · Cited by 600 · see citing works
Connerney, I., Shapiro, P. A., McLaughlin, J. S., Bagiella, E., & Sloan, R. P. (2001) · The Lancet · doi:10.1016/s0140-6736(01)06803-9 · Cited by 495 · see citing works
Impact of pain on depression treatment response in primary care
Bair, M. J., Robinson, R. L., Eckert, G. J., Stang, P. E., Croghan, T. W., & Kroenke, K. (2004) · Psychosomatic Medicine · doi:10.1097/01.psy.0000106883.94059.c5 · Cited by 371 · see citing works
Rollman, B. L., Belnap, B. H., LeMenager, M. S., Mazumdar, S., Houck, P. R., Counihan, P. J., Kapoor, W. N., Schulberg, H. C., & Reynolds, C. F. (2009) · JAMA · doi:10.1001/jama.2009.1670 · Cited by 343 · see citing works
Self-citationPain, Activity Restriction, and Symptoms of Depression Among Community-residing Elderly Adults
Williamson, G. M., & Schulz, R. (1992) · Journal of Gerontology · doi:10.1093/geronj/47.6.p367 · Cited by 321 · see citing works
Mallik, S., Krumholz, H. M., Lin, Z., Kasl, S. V., Mattera, J. A., Roumains, S. A., & Vaccarino, V. (2005) · Circulation · doi:10.1161/01.cir.0000152102.29293.d7 · Cited by 263 · see citing works
Pain Predicts Longer Time to Remission During Treatment of Recurrent Depression
Karp, J. F., Scott, J., Houck, P., Reynolds, C. F., Kupfer, D. J., & Frank, E. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n0508 · Cited by 196 · see citing works
Self-citationFreedland, K. E., Skala, J. A., Carney, R. M., Raczynski, J. M., Taylor, C. B., de Leon, C. F. M., Ironson, G. H., Youngblood, M., Krishnan, K., & Veith, R. C. (2002) · Psychosomatic Medicine · doi:10.1097/01.psy.0000028826.64279.29 · Cited by 155 · see citing works
Taillefer, M.-C., Carrier, M., Bélisle, S. J., Lévesque, S., Lanctôt, H., Boisvert, A.-M., & Choinière, M. (2006) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2006.02.001 · Cited by 110 · see citing works
Predictors of health-related quality of life after coronary artery bypass surgery
Rumsfeld, J. S., Ho, P. M., Magid, D. J., MCCARTHY, M. J., Shroyer, A. L., MaWhinney, S., Grover, F. L., & Hammermeister, K. E. (2004) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2003.10.056 · Cited by 93 · see citing works
Watson, E. K., Firman, D. W., Baade, P. D., & Ring, I. T. (1996) · Australian and New Zealand Journal of Public Health · doi:10.1111/j.1467-842x.1996.tb01046.x · Cited by 78 · see citing works
Rollman, B. L., Belnap, B. H., LeMenager, M. S., Mazumdar, S., Schulberg, H. C., & Reynolds, C. F. (2009) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3181970c1c · Cited by 72 · see citing works
Self-citationPain Limits the Effectiveness of Collaborative Care for Depression
Thielke, S. M., Fan, M., Sullivan, M. D., & Unützer, J. (2007) · American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e3180325a2d · Cited by 68 · see citing works
Body Pain and Treatment Response in Late-Life Depression
Karp, J. F., Weiner, D. K., Seligman, K., Butters, M. A., Miller, M. D., Frank, E., STACK, J. A., Mulsant, B. H., Pollock, B. G., Dew, M. A., et al. (2005) · American Journal of Geriatric Psychiatry · doi:10.1097/00019442-200503000-00003 · Cited by 62 · see citing works
Self-citationPredictors of Chest Pain after Coronary Artery Bypass Grafting
Karlsson, E. B. I. (1999) · Scandinavian Cardiovascular Journal · doi:10.1080/14017439950141542 · Cited by 35 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Collaborative care for depression and anxiety problems
Archer, J., Bower, P., Gilbody, S., Lovell, K., Richards, D., Gask, L., Dickens, C., & Coventry, P. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006525.pub2 · Cited by 1,126 · see citing works
Depression and cardiac disease: epidemiology, mechanisms, and diagnosis.
Huffman, J. C., Celano, C. M., Beach, S. R., Motiwala, S. R., & Januzzi, J. L. (2013) · Cardiovascular Psychiatry and Neurology · doi:10.1155/2013/695925 · Cited by 445 · see citing works
Psychological interventions for acute pain after open heart surgery
Ziehm, S., Rosendahl, J., Barth, J., Strauss, B. M., Mehnert, A., & Koranyi, S. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009984.pub3 · Cited by 56 · see citing works
van der Horst, A. Y., Trompetter, H. R., Pakvis, D. F. M., Kelders, S. M., Schreurs, K. M. G., & Bohlmeijer, E. T. (2019) · International Journal of Orthopaedic and Trauma Nursing · doi:10.1016/j.ijotn.2019.07.003 · Cited by 30 · see citing works
van der Horst, A., Meijer, L., van Os - Medendorp, H., Jukema, J. S., Bohlmeijer, E., Schreurs, K. M., & Kelders, S. (2024) · JMIR Formative Research · doi:10.2196/54600 · Cited by 4 · see citing works
Van Der Horst, A. Y., Bohlmeijer, E. T., Schreurs, K. M. G., & Kelders, S. M. (2023) · Frontiers in Psychology · doi:10.3389/fpsyg.2023.1117357 · Cited by 4 · see citing works
“These information modules served as valuable, practical information, aiming at realistic expectation management as unrealistic or unfulfilled expectations about surgery and preoperative stress may lead to experiencing higher levels of postoperative pain (Iversen et al., 1998; Munafo and Stevenson, 2003; Arpino et al.,…”
Background
- Authors
- Morone, N. E., Weiner, D. K., Herbeck Belnap, B., Karp, J. F., Mazumdar, S., Houck, P. R., He, F., & Rollman, B. L.
- Affiliations
- National Institutes of Health (US)
- Corresponding author
- Morone, Natalia E.
- Venue
- Psychosomatic Medicine
- Published
- 2010-09
- Volume
- 72
- Issue
- 7
- Pages
- 620-625
- ISSN
- 0033-3174 (ISSN-L)
- PMC
- PMC2939235
- OpenAlex
- W2055002695
- Cited by
- 57
- References
- 23
- Citations by year
- 2026: 1 · 2024: 3 · 2023: 7 · 2022: 4 · 2021: 3 · 2020: 5 · 2019: 3 · 2018: 2 · 2017: 6 · 2016: 2 · 2015: 2 · 2014: 7 · 2013: 5 · 2012: 4
- FWCI
- 2.63
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Psychosomatic Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (KL2TR000146)
- National Heart, Lung, and Blood Institute (R01HL070000, R01 HL70000)
- National Center for Research Resources (KL2RR024154)
- National Center for Advancing Translational Sciences
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Surgery › Cardiac and Coronary Surgery Techniques
- Keywords
- coronary artery bypass grafting, depression, postoperative pain, functional recovery, collaborative care, depressive symptoms, physical function, cardiac surgery outcomes
- MeSH terms
- Aged, Anti-Inflammatory Agents, Non-Steroidal, Coronary Artery Bypass, Depressive Disorder, Female, Health Status, Humans, Male, Middle Aged, Pain, Pain Measurement, Postoperative Pain, Patient Care Team, Postoperative Complications, Surveys and Questionnaires, Comorbidity, Treatment Outcome, Outcome Assessment, Health Care
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
