Rectal gonorrhea and chlamydia reinfection is associated with increased risk of HIV seroconversion.

Bernstein, Kyle T; Marcus, Julia L; Nieri, Giuliano; Philip, Susan S; Klausner, Jeffrey D

doi:10.1097/qai.0b013e3181c3ef29

Cited by 360HIV/AIDS Research and InterventionsReproductive tract infections researchHIV, Drug Use, Sexual Risk

Rectal gonorrhea and chlamydia reinfection is associated with increased risk of HIV seroconversion.

Bernstein, Kyle T, Marcus, Julia L, Nieri, Giuliano, Philip, Susan S, Klausner, Jeffrey D·2010·JAIDS Journal of Acquired Immune Deficiency Syndromes

DOI 10.1097/qai.0b013e3181c3ef29

Open this paper in CoChat — free account

Abstract

INTRODUCTION: HIV infection continues to disproportionately affect men who have sex with men (MSM). Identification of modifiable risk factors for HIV infection among MSM is critical for effective prevention. METHODS: We examined the relationship between number of prior rectal Neisseria gonorrhoeae (GC) or Chlamydia trachomatis (CT) infections and HIV seroconversion in a retrospective cohort of HIV-uninfected MSM diagnosed with a rectal infection. Number of rectal CT or GC infections in the prior 2 years was the primary exposure. Univariate and multivariate Cox proportional hazards models were used to estimate the association between prior rectal infections and HIV seroconversion. RESULTS: A total of 541 MSM were observed for a total of 1197.96 person-years. Overall, 27 (4.99%) of the MSM became infected with HIV, for an estimated annual incidence of 2.25% [95% confidence interval (CI): 1.49 to 3.26]. In multivariate analysis, an early syphilis diagnosis in the past 2 years (hazard ratio = 4.04, 95% CI: 1.19 to 13.79) and 2 prior CT or GC rectal infections in the past 2 years (hazard ratio = 8.85, 95% CI: 2.57 to 30.40) were associated with incident HIV. CONCLUSIONS: Among MSM infected with rectal GC or CT, a history of 2 additional prior rectal infections was associated with an 8-fold increased risk of HIV infection. HIV-uninfected MSM with multiple rectal infections represent a population in need of innovative HIV-prevention interventions.

Integrity signals

Registry

Crossref · 10.1097/qai.0b013e3181c3ef29

Cites

44 of 44 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Men with repeat rectal infections can be at substantially higher risk for HIV acquisition.
“and men with repeat rectal infections can be at substantially higher risk for HIV acquisition (208).”
From Sexually Transmitted Infections Treatment Guidelines, 2021 (2021) · cites this paper as [208]

Simulation Study of Confounder-Selection Strategies
Maldonado, G., & Greenland, S. (1993) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a116813 · Cited by 2,491 · see citing works
THE IMPACT OF CONFOUNDER SELECTION CRITERIA ON EFFECT ESTIMATION
Mickey, R. M., & Greenland, S. (1989) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a115101 · Cited by 2,405 · see citing works
RE:“;THE IMPACT OF CONFOUNDER SELECTION CRITERIA ON EFFECT ESTIMATION”
Greenland, S., & Mickey, R. M. (1989) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a115409 · Cited by 2,120 · see citing works
Impact of improved treatment of sexually transmitted diseases on HIV infection in rural Tanzania: randomised controlled trial
Grosskurth, H., Todd, J., Mwijarubi, E., Mayaud, P., Nicoll, A., ka-Gina, G., Newell, J., Grosskurth, H., Todd, J., Mayaud, P., et al. (1995) · The Lancet · doi:10.1016/s0140-6736(95)91380-7 · Cited by 1,404 · see citing works
Concurrent partnerships and the spread of HIV
Morris, M., & Kretzschmar, M. (1997) · AIDS · doi:10.1097/00002030-199705000-00012 · Cited by 984 · see citing works
Reduction of concentration of HIV-1 in semen after treatment of urethritis: implications for prevention of sexual transmission of HIV-1
Cohen, M. S., Hoffman, I., Royce, R. A., Kazembe, P. N., Dyer, J. R., Daly, C. C., Zimba, D., Vernazza, P., Maida, M., Fiscus, S. A., et al. (1997) · The Lancet · doi:10.1016/s0140-6736(97)02190-9 · Cited by 873 · see citing works
Prevalence of rectal, urethral, and pharyngeal chlamydia and gonorrhea detected in 2 clinical settings among men who have sex with men: San Francisco, California, 2003.
Kent, C. K., Chaw, J. K., Wong, W., Liska, S., Gibson, S., Hubbard, G., & Klausner, J. D. (2005) · Clinical Infectious Diseases · doi:10.1086/430704 · Cited by 541 · see citing works
Self-citation
Syphilis and HIV Infection: An Update
Zetola, N. M., & Klausner, J. D. (2007) · Clinical Infectious Diseases · doi:10.1086/513427 · Cited by 369 · see citing works
Self-citation
The associations between cervicovaginal HIV shedding, sexually transmitted diseases and immunosuppression in female sex workers in Abidjan, Côte dʼIvoire
Ghys, P. D., Fransen, K., Diallo, M. O. S., Ettiègne-Traoré, V., Coulibaly, I., Yeboué, K. M., Kalish, M. L., Maurice, C., Whitaker, J. P., Greenberg, A. E., et al. (1997) · AIDS · doi:10.1097/00002030-199712000-00001 · Cited by 358 · see citing works
Condom Use to Prevent Incident STDs
Zenilman, J. M., Weisman, C. S., Rompalo, A. M., Ellish, N. J., Upchurch, D. M., Hook, E. W., & Celentano, D. D. (1995) · Sexually Transmitted Diseases · doi:10.1097/00007435-199501000-00003 · Cited by 322 · see citing works
Control of sexually transmitted diseases for HIV-1 prevention: understanding the implications of the Mwanza and Rakai trials
Grosskurth, H., Gray, R. H., Hayes, R., Mabey, D. C. W., & Wawer, M. J. (2000) · The Lancet · doi:10.1016/s0140-6736(00)02336-9 · Cited by 309 · see citing works
Monthly Antibiotic Chemoprophylaxis and Incidence of Sexually Transmitted Infections and HIV-1 Infection in Kenyan Sex Workers: A Randomized Controlled Trial
Kaul, R., Kimani, J., Nagelkerke, N. J., Fonck, K., Ngugi, E. N., Keli, F., MacDonald, K. S., Maclean, I. W., Bwayo, J. J., Temmerman, M., et al. (2004) · JAMA · doi:10.1001/jama.291.21.2555 · Cited by 257 · see citing works
Socially desirable responding and self-reported HIV infection risk behaviors among intravenous drug users.
Latkin, C., Vlahov, D., & Anthony, J. C. (1993) · Addiction · doi:10.1111/j.1360-0443.1993.tb02058.x · Cited by 218 · see citing works
Increase in Endocervical CD4 Lymphocytes among Women with Nonulcerative Sexually Transmitted Diseases
Levine, W. C., Pope, V., Bhoomkar, A., Tambe, P., Lewis, J. S., Zaidi, A. A., FARSHY, C. E., Mitchell, S., & Talkington, D. F. (1998) · The Journal of Infectious Diseases · doi:10.1086/513820 · Cited by 211 · see citing works
Risk Behaviors by Audio Computer-Assisted Self-Interviews among HIV-Seropositive and HIV-Seronegative Injection Drug Users
Macalino, G. E., Celentano, D. D., Latkin, C. A., et al. (2002) · AIDS Education and Prevention · doi:10.1521/aeap.14.6.367.24075 · Cited by 191 · see citing works
FACTORS ASSOCIATED WITH PREVALENT HUMAN IMMUNODEFICIENCY VIRUS (HIV) INFECTION IN THE MULTICENTER AIDS COHORT STUDY
Chmiel, J. S., Detels, R., Kaslow, R. A., et al. (1987) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a114696 · Cited by 189 · see citing works
RISK FACTORS FOR AIDS AND HIV SEROPOSITIVITY IN HOMOSEXUAL MEN
Moss, A. R., Osmond, D. H., Bacchetti, P., Chermann, J., Barré‐Sinoussi, F., & CARLSON, J. (1987) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a114619 · Cited by 181 · see citing works
HIV risk factors in three geographic strata of rural Rakai District, Uganda
Serwadda, D., Wawer, M. J., Musgrave, S. D., et al. (1992) · AIDS · doi:10.1097/00002030-199209000-00012 · Cited by 175 · see citing works
Distinct Proinflammatory Host Responses to Neisseria gonorrhoeae Infection in Immortalized Human Cervical and Vaginal Epithelial Cells
Fichorova, R. N., Desai, P. J., Gibson, F. C., et al. (2001) · Infection and Immunity · doi:10.1128/iai.69.9.5840-5848.2001 · Cited by 153 · see citing works
A community trial of the impact of improved sexually transmitted disease treatment on the HIV epidemic in rural Tanzania
Grosskurth, H., Mosha, F., Todd, J., et al. (1995) · AIDS · doi:10.1097/00002030-199508000-00015 · Cited by 150 · see citing works
Inflammatory Cytokines Produced in Response to Experimental Human Gonorrhea
Ramsey, K. H., Schneider, H., Cross, A. S., et al. (1995) · The Journal of Infectious Diseases · doi:10.1093/infdis/172.1.186 · Cited by 146 · see citing works
TNF-α and TLR agonists increase susceptibility to HIV-1 transmission by human Langerhans cells ex vivo
de Jong, M. A. W. P., de Witte, L. D., Oudhoff, M. J., Gringhuis, S. I., Gallay, P. A., & Geijtenbeek, T. B. H. (2008) · Journal of Clinical Investigation · doi:10.1172/jci34721 · Cited by 131 · see citing works
High Levels of Tumor Necrosis Factor–α and Interleukin‐1β in Bacterial Vaginosis May Increase Susceptibility to Human Immunodeficiency Virus
Sturm-Ramirez, K. M., Gaye‐Diallo, A., Eisen, G., Mboup, S., & Kanki, P. J. (2000) · The Journal of Infectious Diseases · doi:10.1086/315713 · Cited by 130 · see citing works
Relative risks and population attributable fraction of incident HIV associated with symptoms of sexually transmitted diseases and treatable symptomatic sexually transmitted diseases in Rakai District, Uganda
Gray, R. H., Wawer, M. J., Sewankambo, N. K., Serwadda, D., Li, C., Moulton, L. H., Lutalo, T., Wabwire‐Mangen, F., Meehan, M. P., Ahmed, S., et al. (1999) · AIDS · doi:10.1097/00002030-199910220-00015 · Cited by 128 · see citing works
Seroconversion, sexual activity, and condom use among 2915 HIV seronegative men followed for up to 2 years.
Detels, R., English, P., Visscher, B. R., Jacobson, L. P., Kingsley, L., Chmiel, J. S., Dudley, J. P., Eldred, L. J., & Ginzburg, H. M. (1989) · PubMed · Cited by 126 · see citing works
Reliability of self-reported sexual behavior risk factors for HIV infection in homosexual men.
Saltzman, S. P., Stoddard, A. M., McCusker, J., Moon, M. W., & Mayer, K. H. (1987) · Europe PMC (PubMed Central) · Cited by 120 · see citing works
Association of CD4 Cell Depletion and Elevated Blood and Seminal Plasma Human Immunodeficiency Virus Type 1 (HIV‐1) RNA Concentrations with Genital Ulcer Disease in HIV‐1‐Infected Men in Malawi
Dyer, J. R., Eron, J. J., Hoffman, I., Kazembe, P. N., Vernazza, P., Nkata, E., Daly, C. C., Fiscus, S. A., & Cohen, M. S. (1998) · The Journal of Infectious Diseases · doi:10.1086/517359 · Cited by 117 · see citing works
Risk Among Men Who Have Sex With Men in the United States: A Comparison of an Internet Sample and a Conventional Outreach Sample
Rhodes, S. D., DiClemente, R. J., Cecil, H., Hergenrather, K. C., & Yee, L. J. (2002) · AIDS Education and Prevention · doi:10.1521/aeap.14.1.41.24334 · Cited by 114 · see citing works
Increased interleukin-10 in the endocervical secretions of women with non-ulcerative sexually transmitted diseases: a mechanism for enhanced HIV-1 transmission?
Cohen, C. R., Plummer, F. A., Mugo, N., Maclean, I., Shen, C., Bukusi, E. A., Irungu, E., Sinei, S. K., Bwayo, J. J., & Brunham, R. C. (1999) · AIDS · doi:10.1097/00002030-199902250-00004 · Cited by 113 · see citing works
Rectal gonorrhoea as an independent risk factor for HIV infection in a cohort of homosexual men.
Craib, K. J., Meddings, D. R., Strathdee, S. A., Hogg, R. S., Montaner, J. S., O'Shaughnessy, M. V., & Schechter, M. T. (1995) · Sexually Transmitted Infections · doi:10.1136/sti.71.3.150 · Cited by 98 · see citing works
Exploring the relationship between sexually transmitted diseases and HIV acquisition by using different study designs.
Zetola, N. M., Bernstein, K. T., Wong, E., Louie, B., & Klausner, J. D. (2009) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e318195bd2b · Cited by 83 · see citing works
Self-citation
Gonococcal Infection of Human Fallopian Tube Mucosa in Organ Culture: Relationship of Mucosal Tissue TNF-α Concentration to Sloughing of Ciliated Cells
McGee, Z. A., Jensen, R. L., Clemens, C. M., et al. (1999) · Sexually Transmitted Diseases · doi:10.1097/00007435-199903000-00007 · Cited by 79 · see citing works
Coinfection with Herpes Simplex Virus Type 2 Is Associated with Reduced HIV‐Specific T Cell Responses and Systemic Immune Activation
Sheth, P. M., Sunderji, S., Shin, L. Y., et al. (2008) · The Journal of Infectious Diseases · doi:10.1086/587697 · Cited by 68 · see citing works
Validating the Effects of Social Desirability on Self-Reported Condom Use Behavior among Commercial Sex Workers
Morisky, D. E., Ang, A., & Sneed, C. D. (2002) · AIDS Education and Prevention · doi:10.1521/aeap.14.6.351.24078 · Cited by 63 · see citing works
Condom Use as a Dependent Variable: Measurement Issues Relevant to HIV Prevention Programs
Crosby, R. A. (1998) · AIDS Education and Prevention · doi:10.1521/aeap.1998.10.6.548 · Cited by 60 · see citing works
RISK FACTORS FOR HTV INFECTION IN MALE SEXUAL CONTACTS OF MEN WITH AIDS OR AN AIDS-RELATED CONDITION
Coates, R. A., Calzavara, L., Read, S., Fanning, M. M., Shepherd, F. A., Klein, M. H., JOHNSON, J. K., & Soskolne, C. L. (1988) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a115026 · Cited by 57 · see citing works
Interaction of primary human endometrial cells with Neisseria gonorrhoeae expressing green fluorescent protein
Christodoulides, M., Everson, J. S., Liu, B., et al. (2000) · Molecular Microbiology · doi:10.1046/j.1365-2958.2000.01694.x · Cited by 51 · see citing works
The prevalence of rectal chlamydial infection amongst men who have sex with men attending the genitourinary medicine clinic in Edinburgh
Manavi, K., McMillan, A., & Young, H.-K. (2004) · International Journal of STD & AIDS · doi:10.1258/095646204322916588 · Cited by 46 · see citing works
HIV is hyperendemic among men who have sex with men in San Francisco: 10-year trends in HIV incidence, HIV prevalence, sexually transmitted infections and sexual risk behaviour
Scheer, S., Kellogg, T. A., Klausner, J. D., Schwarcz, S. K., Colfax, G. N., Bernstein, K. T., Louie, B., Dilley, J., Hecht, J., Truong, H.-H. M., et al. (2008) · Sexually Transmitted Infections · doi:10.1136/sti.2008.031823 · Cited by 44 · see citing works
Self-citation
Prevalence of chlamydia and gonorrhoea among a population of men who have sex with men
Cook, R. L. (2002) · Sexually Transmitted Infections · doi:10.1136/sti.78.3.190 · Cited by 36 · see citing works
Human Immunodeficiency Virus Type 1 (HIV‐1) Plasma Virus Load and Markers of Immune Activation among HIV‐Infected Female Sex Workers with Sexually Transmitted Diseases in Abidjan, Côte d'Ivoire
Nkengasong, J. N., Kestens, L., Ghys, P. D., Koblavi‐Dème, S., Bilé, E., Kalou, M. B., Kouadio, L. Y., Ettiègne-Traoré, V., Maurice, C., Laga, M., et al. (2001) · The Journal of Infectious Diseases · doi:10.1086/319855 · Cited by 32 · see citing works
Estimation of HIV incidence in San Francisco
Scheer, S., Chin, C.-S. J., Buckman, A., et al. (2009) · AIDS · doi:10.1097/qad.0b013e328322432b · Cited by 12 · see citing works
Factors Influencing the Risk of Infection with Human Immunodeficiency Virus in Homosexual Men, Denver 1982–1985
RIETMEIJER, C. A. M., Penley, K. A., Cohn, D. L., et al. (1989) · Sexually Transmitted Diseases · doi:10.1097/00007435-198904000-00011 · Cited by 11 · see citing works
Rectal chlamydia in men attending a GU medicine clinic
Chauhan, M., Sankar, K. N., & Pattman, R. S. (2004) · International Journal of STD & AIDS · doi:10.1258/0956462042563611 · Cited by 4 · see citing works

Flagged first, then by citations

Sorted by citations

Sexually Transmitted Infections Treatment Guidelines, 2021
Workowski, K. A., Bachmann, L. H., Chan, P. A., Johnston, C. M., Muzny, C. A., Park, I., Reno, H., Zenilman, J. M., & Bolan, G. A. (2021) · MMWR. Recommendations and Reports · doi:10.15585/mmwr.rr7004a1 · Cited by 2,759 · see citing works
Preexposure prophylaxis for HIV infection integrated with municipal- and community-based sexual health services.
Liu, A. Y., Cohen, S. E., Vittinghoff, E., Anderson, P. L., Doblecki-Lewis, S., Bacon, O., Chege, W., Postle, B. S., Matheson, T., Amico, K. R., et al. (2016) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2015.4683 · Cited by 602 · see citing works
No New HIV Infections With Increasing Use of HIV Preexposure Prophylaxis in a Clinical Practice Setting: Figure 1.
Volk, J. E., Marcus, J. L., Phengrasamy, T., Blechinger, D., Nguyen, D. P., Follansbee, S., & Hare, C. B. (2015) · Clinical Infectious Diseases · doi:10.1093/cid/civ778 · Cited by 489 · see citing works
Self-citation
Extragenital Infections Caused by<i>Chlamydia trachomatis</i>and<i>Neisseria gonorrhoeae</i>: A Review of the Literature
Chan, P. A., Robinette, A., Montgomery, M., Almonte, A., Cu-Uvin, S., Lonks, J. R., Chapin, K. C., Kojic, E. M., & Hardy, E. J. (2016) · Infectious Diseases in Obstetrics and Gynecology · doi:10.1155/2016/5758387 · Cited by 330 · see citing works
Extragenital gonorrhea and chlamydia testing and infection among men who have sex with men—STD Surveillance Network, United States, 2010–2012.
Patton, M. E., Kidd, S., Llata, E., Stenger, M., Braxton, J., Asbel, L., Bernstein, K., Gratzer, B., Jespersen, M., Kerani, R., et al. (2014) · Clinical Infectious Diseases · doi:10.1093/cid/ciu184 · Cited by 206 · see citing works
Syphilis predicts HIV incidence among men and transgender women who have sex with men in a preexposure prophylaxis trial.
Solomon, M. M., Mayer, K. H., Glidden, D. V., Liu, A. Y., McMahan, V. M., Guanira, J. V., Chariyalertsak, S., Fernandez, T., Grant, R. M., Bekker, L.-G., et al. (2014) · Clinical Infectious Diseases · doi:10.1093/cid/ciu450 · Cited by 159 · see citing works
HIV incidence among men with and those without sexually transmitted rectal infections: estimates from matching against an HIV case registry.
Pathela, P., Braunstein, S. L., Blank, S., & Schillinger, J. A. (2013) · Clinical Infectious Diseases · doi:10.1093/cid/cit437 · Cited by 146 · see citing works
The high risk of an HIV diagnosis following a diagnosis of syphilis: a population-level analysis of New York City men.
Pathela, P., Braunstein, S. L., Blank, S., Shepard, C., & Schillinger, J. A. (2015) · Clinical Infectious Diseases · doi:10.1093/cid/civ289 · Cited by 118 · see citing works
The contribution of Mycoplasma genitalium to the aetiology of sexually acquired infectious proctitis in men who have sex with men.
Bissessor, M., Tabrizi, S. N., Bradshaw, C. S., Fairley, C. K., Hocking, J. S., Garland, S. M., Twin, J., Poljak, M., Peel, J., & Chen, M. Y. (2016) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2015.11.016 · Cited by 99 · see citing works
Proportion of incident human immunodeficiency virus cases among men who have sex with men attributable to gonorrhea and chlamydia: a modeling analysis.
Jones, J., Weiss, K., Mermin, J., Dietz, P., Rosenberg, E. S., Gift, T. L., Chesson, H., Sullivan, P. S., Lyles, C., Bernstein, K. T., et al. (2019) · Sexually Transmitted Diseases · doi:10.1097/olq.0000000000000980 · Cited by 94 · see citing works
Self-citation
New human immunodeficiency virus diagnosis independently associated with rectal gonorrhea and chlamydia in men who have sex with men.
Barbee, L. A., Khosropour, C. M., Dombrowksi, J. C., & Golden, M. R. (2017) · Sexually Transmitted Diseases · doi:10.1097/olq.0000000000000614 · Cited by 92 · see citing works
The etiology of infectious proctitis in men who have sex with men differs according to HIV status.
Bissessor, M., Fairley, C. K., Read, T., Denham, I., Bradshaw, C., & Chen, M. (2013) · Sexually Transmitted Diseases · doi:10.1097/olq.0000000000000022 · Cited by 65 · see citing works
Chlamydia, gonorrhea, and human immunodeficiency virus infection among transgender women and transgender men attending clinics that provide sexually transmitted disease services in six US cities: results from the Sexually Transmitted Disease Surveillance Network.
Pitasi, M. A., Kerani, R. P., Kohn, R., Murphy, R. D., Pathela, P., Schumacher, C. M., Tabidze, I., & Llata, E. (2019) · Sexually Transmitted Diseases · doi:10.1097/olq.0000000000000917 · Cited by 61 · see citing works
High burden of chlamydia and gonorrhoea in pharyngeal, rectal and urethral sites among Thai transgender women: implications for anatomical site selection for the screening of STI.
Hiransuthikul, A., Janamnuaysook, R., Sungsing, T., Jantarapakde, J., Trachunthong, D., Mills, S., Vannakit, R., Phanuphak, P., & Phanuphak, N. (2019) · Sexually Transmitted Infections · doi:10.1136/sextrans-2018-053835 · Cited by 25 · see citing works
Bacterial sexually transmitted infection screening rates by symptomatic status among men who have sex with men in the United States: a hierarchical Bayesian analysis.
Jenness, S. M., Weiss, K. M., Prasad, P., Zlotorzynska, M., & Sanchez, T. (2019) · Sexually Transmitted Diseases · doi:10.1097/olq.0000000000000896 · Cited by 18 · see citing works
High incidence of extra-genital gonorrheal and chlamydial infections among high-risk men who have sex with men and transgender women in Peru.
Allan-Blitz, L.-T., Konda, K. A., Calvo, G. M., Vargas, S. K., Leon, S. R., Segura, E. R., Caceres, C. F., & Klausner, J. D. (2018) · International Journal of STD & AIDS · doi:10.1177/0956462417744098 · Cited by 14 · see citing works
Self-citation

Screening Recommendations for Chlamydia and Gonorrhea
Sharon, V. R., & Armstrong, A. W. (2015) · JAMA Dermatology · doi:10.1001/jamadermatol.2015.1987 · Cited by 1 · see citing works
STI phase and the geography of sexual partnerships: Prevalence of long-distance sexual contacts among chlamydia, gonorrhea, and coinfected STI cases in Manitoba, Canada
Hippe, J., & JOLLY, A. M. (2012) · Spatial and Spatio-temporal Epidemiology · doi:10.1016/j.sste.2012.04.001 · Cited by 4 · see citing works
Extragenital gonorrhea and chlamydia testing and infection among men who have sex with men—STD Surveillance Network, United States, 2010–2012.
Patton, M. E., Kidd, S., Llata, E., Stenger, M., Braxton, J., Asbel, L., Bernstein, K., Gratzer, B., Jespersen, M., Kerani, R., et al. (2014) · Clinical Infectious Diseases · doi:10.1093/cid/ciu184 · Cited by 206 · see citing works
Self-citation
Validation of International Classification of Diseases, Tenth Revision, Clinical Modification Codes for Identifying Cases of Chlamydia and Gonorrhea
Ho, Y. A., Rahurkar, S., Tao, G., et al. (2020) · Sexually Transmitted Diseases · doi:10.1097/olq.0000000000001257 · Cited by 17 · see citing works
High Frequencies of Negative Pretreatment Results Following Presumptive Antibiotic Treatment for Chlamydia and Gonorrhea
Andric, B., Drowos, J. L., Trepka, M. J., et al. (2013) · Southern Medical Journal · doi:10.1097/smj.0b013e318291b3c2 · Cited by 10 · see citing works

Authors: Bernstein, K. T., Marcus, J. L., Nieri, G., Philip, S. S., & Klausner, J. D.
Affiliations: San Francisco Department of Public Health (US)
Corresponding author: Bernstein, Kyle T
ORCID: Bernstein, Kyle T
Marcus, Julia L
Philip, Susan S
Klausner, Jeffrey D
Venue: JAIDS Journal of Acquired Immune Deficiency Syndromes
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2010-04-01
Volume: 53
Issue: 4
Pages: 537-543
ISSN: 1525-4135 (ISSN-L)
DOI: 10.1097/qai.0b013e3181c3ef29
OpenAlex: W1976513589
Cited by: 360
References: 44
Citations by year: 2026: 8 · 2025: 13 · 2024: 18 · 2023: 16 · 2022: 20 · 2021: 29 · 2020: 38 · 2019: 32 · 2018: 25 · 2017: 31 · 2016: 26 · 2015: 27 · 2014: 30 · 2013: 16 · 2012: 11
FWCI: 9.71
Type: journal article
Language: en
Open access: closed
Locations: JAIDS Journal of Acquired Immune Deficiency Syndromes (publishedVersion)
PubMed (publishedVersion)
Funders: Centers for Disease Control and Prevention (1h25ps001354-01)
Topics: Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
Keywords: HIV seroconversion, rectal gonorrhea, Neisseria gonorrhoeae, Chlamydia trachomatis, men who have sex with men, reinfection, early syphilis, HIV prevention, risk factors
MeSH terms: Adult, Chlamydia Infections, Gonorrhea, HIV Seropositivity, Humans, Male, Middle Aged, Rectal Diseases, Retrospective Studies, Risk Factors, Incidence, Young Adult

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Rectal gonorrhea and chlamydia reinfection is associated with increased risk of HIV seroconversion.

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Cites

Cited by

Related

Record

About these checks