Computed tomography and magnetic resonance imaging of cardiovascular anomalies associated with Turner syndrome
Abstract
Cardiovascular imaging plays a central role in the diagnosis, management, and follow-up of congenital and acquired cardiovascular disease in patients with Turner syndrome. Cardiovascular defects in this population may affect a single component of the cardiovascular system or exist in combination with other anomalies, and, they may present early in life or remain occult into adulthood. Careful screening and surveillance imaging are necessary for the early detection and management of cardiovascular defects, especially in cases wherein early intervention may be necessary to prevent a serious cardiovascular outcome. It is critical that these patients are followed-up by specialists aware of their unique cardiovascular risk factors and that imaging examinations are interpreted by cardiovascular imagers familiar with the variety of anomalies that may be present and/or warrant imaging follow-up. Herein, we review common and uncommon cardiovascular anomalies associated with Turner syndrome and provide an image-based approach to analyzing key cardiothoracic findings that should be assessed in this patient population. Current imaging recommendations and guidelines for various anomalies will also be reviewed.
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Venous anomalies (anomalous pulmonary veins, left superior vena cava) are more common in TS.
“While venous anomalies (anomalous pulmonary veins, left superior vena cava) are more common in TS, the question remains if malformations of the inferior vena cava or pelvic veins increase the risk for deep venous thrombosis of the lower extremities.395,475”
From Clinical practice guidelines for the care of girls and women with Turner syndrome. (2024) · cites this paper as [475]
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- Authors
- Sigakis, C. J. G., Browne, L. P., Bang, T., Khanna, A., Pruente, R., & Vargas, D.
- Affiliations
- Department of Radiology, Columbus Radiology/Radiology Partners, Columbus, OH
- Children's Hospital Colorado (US)
- Radiology
- University of Colorado Anschutz (US)
- Corresponding author
- Sigakis, Christopher J.G.
- Venue
- Journal of Thoracic Imaging
- Published
- 2019-05
- Volume
- 34
- Issue
- 3
- Pages
- W23-W35
- ISSN
- 0883-5993 (ISSN-L)
- OpenAlex
- W2898737648
- Cited by
- 8
- References
- 45
- Citations by year
- 2024: 3 · 2023: 1 · 2021: 2 · 2020: 1 · 2019: 1
- FWCI
- 0.14
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Thoracic Imaging (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Congenital Heart Disease Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Cardiac Imaging and Diagnostics
- Keywords
- Turner syndrome, cardiovascular anomalies, congenital heart disease, computed tomography, magnetic resonance imaging, cardiovascular screening, surveillance imaging, image interpretation, cardiovascular risk factors, imaging guidelines
- MeSH terms
- Cardiovascular System, Female, Humans, Magnetic Resonance Imaging, Tomography, X-Ray Computed, Turner Syndrome, Cardiovascular Abnormalities
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