The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Sacral Nerve Stimulation for Fecal Incontinence: Results of a 120-Patient Prospective Multicenter Study
Abstract
In Brief Background: Sacral nerve stimulation has been approved for use in treating urinary incontinence in the United States since 1997, and in Europe for both urinary and fecal incontinence (FI) since 1994. The purpose of this study was to determine the safety and efficacy of sacral nerve stimulation in a large population under the rigors of Food and Drug Administration-approved investigational protocol. Methods: Candidates for SNS who provided informed consent were enrolled in this Institutional Review Board-approved multicentered prospective trial. Patients showing ≥50% improvement during test stimulation received chronic implantation of the InterStim Therapy (Medtronic; Minneapolis, MN). The primary efficacy objective was to demonstrate that ≥50% of subjects would achieve therapeutic success, defined as ≥50% reduction of incontinent episodes per week at 12 months compared with baseline. Results: A total of 133 patients underwent test stimulation with a 90% success rate, and 120 (110 females) of a mean age of 60.5 years and a mean duration of FI of 6.8 years received chronic implantation. Mean follow-up was 28 (range, 2.2–69.5) months. At 12 months, 83% of subjects achieved therapeutic success (95% confidence interval: 74%–90%; P < 0.0001), and 41% achieved 100% continence. Therapeutic success was 85% at 24 months. Incontinent episodes decreased from a mean of 9.4 per week at baseline to 1.9 at 12 months and 2.9 at 2 years. There were no reported unanticipated adverse device effects associated with InterStim Therapy. Conclusion: Sacral nerve stimulation using InterStim Therapy is a safe and effective treatment for patients with FI. The purpose of this study was to determine the safety and efficacy of SNS in a large population under the rigors of an FDA-approved investigational protocol. 133 patients underwent test stimulation with a 90% success rate, and 120 (110 females), of a mean age of 60.5 years and a mean FI duration of 6.8 years, received chronic implantation. Sacral nerve stimulation using IterStim Therapy is a safe and effective treatment for patients with FI.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Etiology and management of fecal incontinence
Jorge, M. J. N., & Wexner, S. D. (1993) · Diseases of the Colon & Rectum · doi:10.1007/bf02050307 · Cited by 2,985
Self-citationRockwood, T. H., Church, J. M., Fleshman, J. W., Kane, R. L., Mavrantonis, C., Thorson, A. G., Wexner, S. D., Bliss, D., & Lowry, A. C. (2000) · Diseases of the Colon & Rectum · doi:10.1007/bf02237236 · Cited by 1,244
Self-citationRockwood, T. H., Church, J. M., Fleshman, J. W., Kane, R. L., Mavrantonis, C., Thorson, A. G., Wexner, S. D., Bliss, D., & Lowry, A. C. (1999) · Diseases of the Colon & Rectum · doi:10.1007/bf02236199 · Cited by 809
Self-citationThird degree obstetric anal sphincter tears: risk factors and outcome of primary repair
Sultan, A. H., Kamm, M. A., Hudson, C. N., & Bartram, C. I. (1994) · BMJ · doi:10.1136/bmj.308.6933.887 · Cited by 761
Defecation frequency and timing, and stool form in the general population: a prospective study.
Heaton, K. W., Radvan, J., Cripps, H., Mountford, R. A., Braddon, F. E., & Hughes, A. O. (1992) · Gut · doi:10.1136/gut.33.6.818 · Cited by 733
Community-Based Prevalence of Anal Incontinence
Nelson, R. (1995) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1995.03530070057030 · Cited by 709
Electrical stimulation of sacral spinal nerves for treatment of faecal incontinence
Matzel, K. E., Stadelmaie, U., Gall, F. P., & Hohenfellner, M. (1995) · The Lancet · doi:10.1016/s0140-6736(95)91799-3 · Cited by 588
Long-term results of overlapping anterior anal-sphincter repair for obstetric trauma
Malouf, A. J., Norton, C. S., Engel, A. F., Nicholls, R. J., & Kamm, M. A. (2000) · The Lancet · doi:10.1016/s0140-6736(99)05218-6 · Cited by 503
SACRAL NERVE STIMULATION FOR TREATMENT OF REFRACTORY URINARY URGE INCONTINENCE
SCHMIDT, R. A., JONAS, U., OLESON, K. A., JANKNEGT, R. A., HASSOUNA, M. M., SIEGEL, S. W., & van KERREBROECK, P. E. V. (1999) · Journal of Urology · doi:10.1016/s0022-5347(05)68558-8 · Cited by 463
Electrical Stimulation in the Clinical Management of the Neurogenic Bladder
Tanagho, E. A., & Schmidt, R. A. (1988) · Journal of Urology · doi:10.1016/s0022-5347(17)42038-6 · Cited by 425
Cited by
Management of functional constipation in children and adults
Vriesman, M. H., Koppen, I. J. N., Camilleri, M., Di Lorenzo, C., & Benninga, M. A. (2020) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-019-0222-y · Cited by 457
Low Anterior Resection Syndrome: Current Management and Future Directions
Berger, N., Ludwig, K., & Ridolfi, T. (2016) · Clinics in Colon and Rectal Surgery · doi:10.1055/s-0036-1584500 · Cited by 88
Metadata
- Authors
- Wexner, S. D., Coller, J. A., Devroede, G., Hull, T., McCallum, R., Chan, M., Ayscue, J. M., Shobeiri, A. S., Margolin, D., England, M., Kaufman, H., Snape, W. J., Mutlu, E., Chua, H., Pettit, P., Nagle, D., Madoff, R. D., Lerew, D. R., & Mellgren, A.
- Venue
- Annals of Surgery
- Published
- 2010-03
- Volume
- 251
- Issue
- 3
- Pages
- 441-449
- ISSN
- 0003-4932 (ISSN-L)
- OpenAlex
- W2011144550
- Cited by
- 351
- References
- 36
- FWCI
- 19.67
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Sacral Nerve Stimulation for Fecal Incontinence: Results of a 120-Patient Prospective Multicenter Study. https://app.cochat.ai/papers/10.1097/sla.0b013e3181cf8ed0
- The paper
- Wexner, S. D., Coller, J. A., Devroede, G., Hull, T., McCallum, R., Chan, M., Ayscue, J. M., Shobeiri, A. S., Margolin, D., England, M., Kaufman, H., Snape, W. J., Mutlu, E., Chua, H., Pettit, P., Nagle, D., Madoff, R. D., Lerew, D. R., & Mellgren, A. (2010). Sacral Nerve Stimulation for Fecal Incontinence: Results of a 120-Patient Prospective Multicenter Study. Annals of Surgery. https://doi.org/10.1097/sla.0b013e3181cf8ed0
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
