Cited by 220Medication Adherence and CompliancePharmacy and Medical PracticesRenal Transplantation Outcomes and Treatments

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The Psychometric Properties and Practicability of Self-Report Instruments to Identify Medication Nonadherence in Adult Transplant Patients: A Systematic Review

Dobbels, Fabienne, Berben, Lut, De Geest, Sabina, Drent, Gerda, Lennerling, Annette, Whittaker, Clare, Kugler, Christiane·2010·Transplantation

DOI 10.1097/tp.0b013e3181e346cd

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Abstract

INTRODUCTION: Nonadherence to immunosuppressive therapy is recognized as a key prognostic indicator for poor posttransplantation long-term outcomes. Several methods aiming to measure medication nonadherence have been suggested in the literature. Although combining measurement methods is regarded as the gold standard for measuring nonadherence, self-report is generally considered a central component of adherence assessment. However, no systematic review currently exists to determine which instrument(s) are most appropriate for use in transplant populations. METHODOLOGY: The transplant360 Task Force first performed a survey of the self-report adherence instruments currently used in European centers. Next, a systematic literature review of self-report instruments assessing medication adherence in chronically ill patients was conducted. Self-report instruments were evaluated to assess those which were: (a) short and easy to score; (b) assessed both the taking and timing of medication intake; and (c) had established reliability and validity. RESULTS: Fourteen instruments were identified from our survey of European centers, of which the Basel Assessment of Adherence Scale for Immunosuppressives met the aforementioned criteria. The systematic review found 20 self-report instruments, of which only two qualified for use in transplantation, that is, the Brief Antiretroviral Adherence Index and the Medication Adherence Self-Report Inventory. DISCUSSION: The three selected self-report scales may assist transplant professionals in detecting nonadherence. However, these scales were only validated in patients with HIV. Although HIV shares similar characteristics with transplantation, including the importance of taking and timing of medication, further validation in transplant populations is required.

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Retracted
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WITHDRAWN: Executive Summary - The International Society for Heart and Lung Transplantation (ISHLT) guidelines for the care of heart transplant recipients
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Self-citation
Retracted
Association Between Regulatory Emotional Self-Efficacy and Immunosuppressive Medication Adherence in Renal Transplant Recipients:Does Medication Belief Act as a Mediator?
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Authors: Dobbels, F., Berben, L., De Geest, S., Drent, G., Lennerling, A., Whittaker, C., & Kugler, C.
Affiliations: KU Leuven (BE)
University of Basel (CH)
University Medical Center Groningen (NL)
Sahlgrenska University Hospital (SE)
Royal London Hospital (GB)
Medizinische Hochschule Hannover (DE)
Corresponding author: Dobbels, Fabienne
ORCID: Dobbels, Fabienne
Berben, Lut
Drent, Gerda
Lennerling, Annette
Venue: Transplantation
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2010-07-27
Volume: 90
Issue: 2
Pages: 205-219
ISSN: 0041-1337 (ISSN-L)
DOI: 10.1097/tp.0b013e3181e346cd
OpenAlex: W2116897123
Cited by: 220
References: 54
Citations by year: 2025: 11 · 2024: 6 · 2023: 20 · 2022: 27 · 2021: 21 · 2020: 19 · 2019: 21 · 2018: 14 · 2017: 15 · 2016: 12 · 2015: 12 · 2014: 10 · 2013: 14 · 2012: 9
FWCI: 1.96
Type: journal article
Language: en
Open access: closed
Locations: Transplantation (publishedVersion)
PubMed (publishedVersion)
University of Groningen research database (University of Groningen / Centre for Information Technology) (publishedVersion)
University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
Topics: Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
Health Sciences › Health Professions › Pharmacy › Pharmacy and Medical Practices
Health Sciences › Medicine › Transplantation › Renal Transplantation Outcomes and Treatments
Keywords: medication non-adherence, transplant recipients, immunosuppressive therapy, psychometric properties, adherence measurement, instrument validation
MeSH terms: Assessment of Medication Adherence, Adult, Humans, Immunosuppression Therapy, Prognosis, Psychometrics, Surveys and Questionnaires, Transplantation, Reproducibility of Results, Treatment Outcome, Drug Monitoring, Risk Assessment, Patient Selection, Medication Adherence

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The Psychometric Properties and Practicability of Self-Report Instruments to Identify Medication Nonadherence in Adult Transplant Patients: A Systematic Review

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