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Perspectives on the basic reproductive ratio

Open access
Heffernan, J.M, Smith, R.J, Wahl, L.M·2005·Journal of The Royal Society Interface

Abstract

The basic reproductive ratio,R0, is defined as the expected number of secondary infections arising from a single individual during his or her entire infectious period, in a population of susceptibles. This concept is fundamental to the study of epidemiology and within-host pathogen dynamics. Most importantly,R0 often serves as a threshold parameter that predicts whether an infection will spread. Related parameters which share this threshold behaviour, however, may or may not give the true value of R0. In this paper we give a brief overview of common methods of formulating R0 and surrogate threshold parameters from deterministic, non-structured models. We also review common means of estimating R0 from epidemiological data. Finally, we survey the recent use of R0 in assessing emerging diseases, such as severe acute respiratory syndrome and avian influenza, a number of recent livestock diseases, and vector-borne diseases malaria, dengue and West Nile virus.

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Metadata

Authors
Heffernan, J. M., Smith, R. J., & Wahl, L. M.
Venue
Journal of The Royal Society Interface
Published
2005-06-07
Volume
2
Issue
4
Pages
281-293
ISSN
  • 1742-5662 (ISSN-L)
  • 1742-5689
OpenAlex
W1967940959
Cited by
1,228
References
3
FWCI
15.85
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Perspectives on the basic reproductive ratio. https://app.cochat.ai/papers/10.1098/rsif.2005.0042
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Heffernan, J. M., Smith, R. J., & Wahl, L. M. (2005). Perspectives on the basic reproductive ratio. Journal of The Royal Society Interface. https://doi.org/10.1098/rsif.2005.0042

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.