The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.
Microfluidic systems for chemical kinetics that rely on chaotic mixing in droplets
Open accessAbstract
This paper reviews work on a microfluidic system that relies on chaotic advection to rapidly mix multiple reagents isolated in droplets (plugs). Using a combination of turns and straight sections, winding microfluidic channels create unsteady fluid flows that rapidly mix the multiple reagents contained within plugs. The scaling of mixing for a range of channel widths, flow velocities and diffusion coefficients has been investigated. Due to rapid mixing, low sample consumption and transport of reagents with no dispersion, the system is particularly appropriate for chemical kinetics and biochemical assays. The mixing occurs by chaotic advection and is rapid (sub-millisecond), allowing for an accurate description of fast reaction kinetics. In addition, mixing has been characterized and explicitly incorporated into the kinetic model.
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Cites
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Cited by
Teh, S.-Y., Lin, R., Hung, L.-H., & Lee, A. P. (2008) · Lab on a Chip · doi:10.1039/b715524g · Cited by 2,690
Microfluidic lab-on-a-chip platforms: requirements, characteristics and applications
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Seemann, R., Brinkmann, M., Pfohl, T., & Herminghaus, S. (2012) · Reports on Progress in Physics · doi:10.1088/0034-4885/75/1/016601 · Cited by 1,049
Multiphase microfluidics: from flow characteristics to chemical and materials synthesis
Günther, A., & Jensen, K. F. (2006) · Lab Chip · doi:10.1039/b609851g · Cited by 983
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Metadata
- Authors
- Bringer, M. R., Gerdts, C. J., Song, H., Tice, J. D., & Ismagilov, R. F.
- Venue
- Philosophical Transactions of the Royal Society of London. Series A: Mathematical, Physical and Engineering Sciences
- Publisher
- The Royal Society
- Published
- 2004-05-15
- Volume
- 362
- Issue
- 1818
- Pages
- 1087-1104
- ISSN
- 1364-503X (ISSN-L)
- 1471-2962
- OpenAlex
- W2003339931
- Cited by
- 416
- References
- 34
- FWCI
- 10.85
- Type
- journal article
- Language
- en
- Open access
- green
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- Bringer, M. R., Gerdts, C. J., Song, H., Tice, J. D., & Ismagilov, R. F. (2004). Microfluidic systems for chemical kinetics that rely on chaotic mixing in droplets. Philosophical Transactions of the Royal Society of London. Series A: Mathematical, Physical and Engineering Sciences. https://doi.org/10.1098/rsta.2003.1364
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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