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Examination of faecal Bifidobacterium populations in breast- and formula-fed infants during the first 18 months of life

Roger, Laure C., Costabile, Adele, Holland, Diane T., Hoyles, Lesley, McCartney, Anne L.·2010·Microbiology

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Abstract

Bifidobacteria in the infant faecal microbiota have been the focus of much interest, especially during the exclusive milk-feeding period and in relation to the fortification of infant formulae to better mimic breast milk. However, longitudinal studies examining the diversity and dynamics of the Bifidobacterium population of infants are lacking, particularly in relation to the effects of weaning. Using a polyphasic strategy, the Bifidobacterium populations of breast- and formula-fed infants were examined during the first 18 months of life.Bifidobacterium-specific denaturing gradient gel electrophoresis demonstrated that breast-fed infants harboured greater diversity than formula-fed infants and the diversity of the infants'Bifidobacterium populations increased with weaning. Twenty-seven distinctive banding profiles were observed from ∼1100 infant isolates using ribosomal intergenic spacer analysis, 14 biotypes of which were confirmed to be members of the genus Bifidobacterium. Two profiles (H,Bifidobacterium longum subsp.infantis; and I,Bifidobacterium bifidum) were common culturable biotypes, seen in 9/10 infants, while profile E (Bifidobacterium breve) was common among breast-fed infants. Overall, inter- and intra-individual differences were observed in the Bifidobacterium populations of infants between 1 and 18 months of age, although weaning was associated with increased diversity of the infant Bifidobacterium populations. Breast-fed infants generally harboured a more complex Bifidobacterium microbiota than formula-fed infants.

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Development of the Human Infant Intestinal Microbiota
Palmer, C., Bik, E. M., DiGiulio, D. B., Relman, D. A., & Brown, P. O. (2007) · PLoS Biology · doi:10.1371/journal.pbio.0050177 · Cited by 2,877
Succession of microbial consortia in the developing infant gut microbiome
Koenig, J. E., Spor, A., Scalfone, N., Fricker, A. D., Stombaugh, J., Knight, R., Angenent, L. T., & Ley, R. E. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1000081107 · Cited by 2,540
Developmental microbial ecology of the neonatal gastrointestinal tract
Mackie, R. I., Sghir, A., & Gaskins, H. R. (1999) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/69.5.1035s · Cited by 1,360
Analysis of Intestinal Flora Development in Breast-Fed and Formula-Fed Infants by Using Molecular Identification and Detection Methods
Harmsen, H. J. M., Wildeboer-Veloo, A. C. M., Raangs, G. C., Wagendorp, A. A., Klijn, N., BINDELS, J. G., & Welling, G. W. (2000) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/00005176-200001000-00019 · Cited by 1,326
Probiotics in the management of atopic eczema
Isolauri, E., Arvola, T., Sütas, Y., Moilanen, E., & Salminen, S. (2000) · Clinical & Experimental Allergy · doi:10.1046/j.1365-2222.2000.00943.x · Cited by 981
Feeding of Bifidobacterium bifidum and Streptococcus thermophilus to infants in hospital for prevention of diarrhoea and shedding of rotavirus
Saavedra, J. M., Bauman, N. A., Perman, J. A., Yolken, R. H., Saavedra, J. M., Bauman, N. A., & Oung, I. (1994) · The Lancet · doi:10.1016/s0140-6736(94)91708-6 · Cited by 958
Comparative metagenomics revealed commonly enriched gene sets in human gut microbiomes
Kurokawa, K., Itoh, T., Kuwahara, T., Oshima, K., Toh, H., Toyoda, A., Takami, H., Morita, H., Sharma, V. K., Srivastava, T. P., et al. (2007) · DNA Research · doi:10.1093/dnares/dsm018 · Cited by 869
Molecular Microbial Ecology Manual
Kowalchuk, G. A., de Bruijn, F. J., Head, I. M., Akkermans, A. D. L., & van, E. J. (2004) · Springer eBooks · doi:10.1007/978-1-4020-2177-0 · Cited by 808
Intestinal microflora in early infancy: composition and development
Fanaro, S., Chierici, R., Guerrini, P., & Vigi, V. (2003) · Acta Paediatrica · doi:10.1111/j.1651-2227.2003.tb00646.x · Cited by 738
Comparative analysis of fecal DNA extraction methods with phylogenetic microarray: Effective recovery of bacterial and archaeal DNA using mechanical cell lysis
Salonen, A., Nikkilä, J., Jalanka, J., Immonen, O., Rajilić-Stojanović, M. D., Kekkonen, R. A., Palva, A., & de Vos, W. M. (2010) · Journal of Microbiological Methods · doi:10.1016/j.mimet.2010.02.007 · Cited by 606
Relation of infant diet to childhood health: seven year follow up of cohort of children in Dundee infant feeding study
Wilson, A. C., Forsyth, J. S., Greene, S. A., Irvine, L. A., Hau, C., & Howie, P. (1998) · BMJ · doi:10.1136/bmj.316.7124.21 · Cited by 581
Quantitative PCR with 16S rRNA-Gene-Targeted Species-Specific Primers for Analysis of Human Intestinal Bifidobacteria
Matsuki, T., Watanabe, K., Fujimoto, J., Kado, Y., Takada, T., Matsumoto, K., & Tanaka, R. (2004) · Applied and Environmental Microbiology · doi:10.1128/aem.70.1.167-173.2004 · Cited by 498
Distribution of Bifidobacterial Species in Human Intestinal Microflora Examined with 16S rRNA-Gene-Targeted Species-Specific Primers
Matsuki, T., Watanabe, K., Tanaka, R., Fukuda, M., & Oyaizu, H. (1999) · Applied and Environmental Microbiology · doi:10.1128/aem.65.10.4506-4512.1999 · Cited by 457
Bifidobacterial Diversity in Human Feces Detected by Genus-Specific PCR and Denaturing Gradient Gel Electrophoresis
Satokari, R. M., Vaughan, E. E., Akkermans, A. D. L., Saarela, M., & de Vos, W. M. (2001) · Applied and Environmental Microbiology · doi:10.1128/aem.67.2.504-513.2001 · Cited by 444
A 16S rRNA-targeted Probe for Detection of Lactobacilli and Enterococci in Faecal Samples by FluorescentIn SituHybridization
Harmsen, P. E. H. J. M., Elfferich, P., Schut, F., & Welling, G. W. (1999) · Microbial Ecology in Health and Disease · doi:10.1080/089106099435862 · Cited by 376
Aberrant composition of gut microbiota of allergic infants: a target of bifidobacterial therapy at weaning?
Kirjavainen, P. V., Arvola, T., Salminen, S., & Isolauri, E. (2002) · Gut · doi:10.1136/gut.51.1.51 · Cited by 359
Exploring the Diversity of the Bifidobacterial Population in the Human Intestinal Tract
Turroni, F., Foroni, E., Pizzetti, P., Giubellini, V., Ribbera, A., Merusi, P., Cagnasso, P., Bizzarri, B., de'Angelis, G. L., Shanahan, F., et al. (2009) · Applied and Environmental Microbiology · doi:10.1128/aem.02216-08 · Cited by 311
Development of 16S rRNA-Based Probes for the Coriobacterium Group and the Atopobium Cluster and Their Application for Enumeration of Coriobacteriaceae in Human Feces from Volunteers of Different Age Groups
Harmsen, H. J. M., Wildeboer-Veloo, A. C. M., Grijpstra, J., Knol, J., Degener, J. E., & Welling, G. W. (2000) · Applied and Environmental Microbiology · doi:10.1128/aem.66.10.4523-4527.2000 · Cited by 309
Molecular analysis of the composition of the bifidobacterial and lactobacillus microflora of humans
McCartney, A. L., Wenzhi, W., & Tannock, G. W. (1996) · Applied and Environmental Microbiology · doi:10.1128/aem.62.12.4608-4613.1996 · Cited by 294
Self-citation
Analysis of fecal populations of bifidobacteria and lactobacilli and investigation of the immunological responses of their human hosts to the predominant strains
Kimura, K., McCartney, A. L., McConnell, M. A., & Tannock, G. W. (1997) · Applied and Environmental Microbiology · doi:10.1128/aem.63.9.3394-3398.1997 · Cited by 249
Self-citation
Comparative Metagenomics and Population Dynamics of the Gut Microbiota in Mother and Infant
Vaishampayan, P., Kuehl, J. V., Froula, J. L., Morgan, J. L., Ochman, H., & Francino, M. P. (2010) · Genome Biology and Evolution · doi:10.1093/gbe/evp057 · Cited by 248
Breast-Feeding Lowers the Frequency and Duration of Acute Respiratory Infection and Diarrhea in Infants under Six Months of Age
López-Alarcón, M., Villalpando, S., & Fajardo, A. (1997) · Journal of Nutrition · doi:10.1093/jn/127.3.436 · Cited by 234
Human milk provides peptides highly stimulating the growth of bifidobacteria
Liepke, C., Adermann, K., Raida, M., Mägert, H., Forssmann, W., & Zucht, H. (2002) · European Journal of Biochemistry · doi:10.1046/j.0014-2956.2001.02712.x · Cited by 219
16S rRNA and 16S to 23S Internal Transcribed Spacer Sequence Analyses Reveal Inter- and Intraspecific Bifidobacterium Phylogeny
Leblond‐Bourget, N., Philippe, H., Mangin, I., & Decaris, B. (1996) · International Journal of Systematic Bacteriology · doi:10.1099/00207713-46-1-102 · Cited by 206
Protective Nutrients and Bacterial Colonization in the Immature Human Gut
Dai, D., & Walker, W. A. (1999) · Advances in Pediatrics · doi:10.1016/s0065-3101(24)00035-5 · Cited by 192
Characterisation of intestinal bacteria in infant stools using real-time PCR and northern hybridisation analyses
Hopkins, M. J., Macfarlane, G. T., Furrie, E., Fite, A., & Macfarlane, S. (2005) · FEMS Microbiology Ecology · doi:10.1016/j.femsec.2005.03.001 · Cited by 170
Lessons from the genomes of bifidobacteria
Klijn, A., Mercenier, A., & Arigoni, F. (2005) · FEMS Microbiology Reviews · doi:10.1016/j.femsre.2005.04.010 · Cited by 164
Improvement of Lactose Digestion in Humans by Ingestion of Unfermented Milk Containing Bifidobacterium longum
Jiang, T., Mustapha, A., & Savaiano, D. A. (1996) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(96)76422-6 · Cited by 159
Microbiomic analysis of the bifidobacterial population in the human distal gut
Turroni, F., Marchesi, J. R., Foroni, E., Gueimonde, M., Shanahan, F., Margolles, A., van Sinderen, D., & Ventura, M. (2009) · The ISME Journal · doi:10.1038/ismej.2009.19 · Cited by 137
Breast Feeding and the Intestinal Microflora of the Infant — Implications for Protection Against Infectious Diseases
Wold, A. E., & Adlerberth, I. (2005) · Kluwer Academic Publishers eBooks · doi:10.1007/0-306-46830-1_7 · Cited by 134
Lessons from the genomes of bifidobacteria
Klijn, A., Mercenier, A., & Arigoni, F. (2005) · FEMS Microbiology Reviews · doi:10.1016/j.fmrre.2005.04.010 · Cited by 128
Molecular microbial analysis of Bifidobacterium isolates from different environments by the species-specific amplified ribosomal DNA restriction analysis (ARDRA)
Ventura, M., Elli, M., Reniero, R., & Zink, R. (2001) · FEMS Microbiology Ecology · doi:10.1111/j.1574-6941.2001.tb00831.x · Cited by 127
Longitudinal investigation of the faecal microbiota of healthy full-term infants using fluorescence in situ hybridization and denaturing gradient gel electrophoresis
Roger, L. C., & McCartney, A. L. (2010) · Microbiology · doi:10.1099/mic.0.041913-0 · Cited by 118
Self-citation
Intestinal flora and human health.
MITSUOKA, T. (1996) · PubMed · Cited by 108
Mixed-Species Genomic Microarray Analysis of Fecal Samples Reveals Differential Transcriptional Responses of Bifidobacteria in Breast- and Formula-Fed Infants
Klaassens, E. S., Boesten, R. J., Haarman, M., Knol, J., Schuren, F. H. J., Vaughan, E. E., & de Vos, W. M. (2009) · Applied and Environmental Microbiology · doi:10.1128/aem.02492-08 · Cited by 107
Detection of Bifidobacteria by Using Propionic Acid as a Selective Agent
Beerens, H. (1991) · Applied and Environmental Microbiology · doi:10.1128/aem.57.8.2418-2419.1991 · Cited by 103
Age and prevalence of Porphyromonas gingivalis in children
Mcclellan, D. L., Griffen, A. L., & Leys, E. J. (1996) · Journal of Clinical Microbiology · doi:10.1128/jcm.34.8.2017-2019.1996 · Cited by 87
Fecal microflora of Greek healthy neonates
Mitsou, E. K., Kirtzalidou, E., Oikonomou, I., Liosis, G., & Kyriacou, A. (2007) · Anaerobe · doi:10.1016/j.anaerobe.2007.11.002 · Cited by 86
Culture-independent analysis of fecal microbiota in infants, with special reference toBifidobacteriumspecies
Sakata, S., 外岡, 俊., 石関, し., Takada, M., Sakamoto, M., Fukuyama, M., & Benno, Y. (2005) · FEMS Microbiology Letters · doi:10.1016/j.femsle.2005.01.002 · Cited by 85
Breast milk – immunomodulatory signals against allergic diseases
Hoppu, U., Kalliomäki, M. A., Laiho, K., & Isolauri, E. (2001) · Allergy · doi:10.1034/j.1398-9995.2001.00908.x · Cited by 76
Differentiation of Closely Related Carnobacterium Food Isolates Based on 16S-23S Ribosomal DNA Intergenic Spacer Region Polymorphism
Kabadjova, P., Dousset, X., Cam, V. L., & Prévost, H. (2002) · Applied and Environmental Microbiology · doi:10.1128/aem.68.11.5358-5366.2002 · Cited by 71
Population Dynamics of Bifidobacterium Species in Human Feces during Raffinose Administration Monitored by Fluorescence In Situ Hybridization-Flow Cytometry
Dinoto, A., Marques, T. M., Sakamoto, K., Fukiya, S., Watanabe, J., Ito, S., & Yokota, A. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.01777-06 · Cited by 63
How high G+C Gram-positive bacteria and in particular bifidobacteria cope with heat stress: protein players and regulators
Ventura, M., Canchaya, C. A., Zhang, Z., Bernini, V., Fitzgerald, G. F., & van Sinderen, D. (2006) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2006.00031.x · Cited by 62
Biotin Production by Bifidobacteria.
Noda, H., AKASAKA, N., & Ohsugi, M. (1994) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.40.181 · Cited by 45
Cluster analysis and statistical comparison of molecular community profile data.
van Verseveld, H. W., & Röling, W. F. M. (2004) · VU Research Portal · Cited by 43
Protective Effect of Breastfeeding Against Infection in the First and Second Six Months of Life
Howie, P. (2002) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-0559-4_16 · Cited by 29

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Authors: Roger, L. C., Costabile, A., Holland, D. T., Hoyles, L., & McCartney, A. L.
Affiliations: University of Reading (GB)
ORCID: Costabile, Adele
Hoyles, Lesley
McCartney, Anne L.
Venue: Microbiology
Publisher: Microbiology Society
Published: 2010-11-01
Volume: 156
Issue: 11
Pages: 3329-3341
ISSN: 1350-0872 (ISSN-L)
1465-2080
DOI: 10.1099/mic.0.043224-0
OpenAlex: W2101219158
Cited by: 291
References: 45
Citations by year: 2026: 2 · 2025: 8 · 2024: 18 · 2023: 12 · 2022: 14 · 2021: 24 · 2020: 24 · 2019: 16 · 2018: 20 · 2017: 26 · 2016: 25 · 2015: 29 · 2014: 21 · 2013: 17 · 2012: 18
FWCI: 15.80
Type: journal article
Language: en
Open access: closed
Locations: Microbiology (publishedVersion)
PubMed (publishedVersion)
CentAUR (University of Reading) (submittedVersion)
Topics: Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
Keywords: Bifidobacterium, infant gut microbiota, breastfeeding, infant formula, weaning, microbial diversity, Bifidobacterium longum subsp. infantis, Bifidobacterium bifidum, Bifidobacterium breve, polyphasic identification, RISA, denaturing gradient gel electrophoresis
MeSH terms: Bifidobacterium, Breast Feeding, DNA, Bacterial, Feces, Humans, Infant, Longitudinal Studies, Species Specificity, Weaning, DNA, Ribosomal Spacer, Infant Formula, Biodiversity, Denaturing Gradient Gel Electrophoresis

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Examination of faecal Bifidobacterium populations in breast- and formula-fed infants during the first 18 months of life

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