The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.
Candida albicans drug resistance—Another way to cope with stress
Abstract
There are relatively few classes of antifungal drugs. This restricts clinicians' therapeutic choices and these choices are further reduced by the emergence of drug resistance. Exposure to antifungal drugs represents an environmental stress for the fungal pathogen Candida albicans. The immediate response of C. albicans to antifungals may be drug tolerance, which can lead to drug resistance. This article examines C. albicans drug resistance from the perspective of it being a stress response and investigates how commonality with other stress-response pathways gives insights into the prospects for overcoming, or preventing, drug resistance.
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“However, iron limitation increased the susceptibility of dispersed daughter cells from biofilms to amphotericin B, detected by a number of cells which induce responses by signalling pathways [162].”
From Candida glabrata Biofilms: How Far Have We Come? (2017) · cites this paper as [162]
Citations
Cites
The antibiotic resistome: the nexus of chemical and genetic diversity
Wright, G. D. (2007) · Nature Reviews Microbiology · doi:10.1038/nrmicro1614 · Cited by 1,421
Clinical, Cellular, and Molecular Factors That Contribute to Antifungal Drug Resistance
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Aneuploidy and Isochromosome Formation in Drug-Resistant Candida albicans
Selmecki, A., Forche, A., & Berman, J. (2006) · Science · doi:10.1126/science.1128242 · Cited by 733
Hsp90 Potentiates the Rapid Evolution of New Traits: Drug Resistance in Diverse Fungi
Cowen, L. E., & Lindquist, S. (2005) · Science · doi:10.1126/science.1118370 · Cited by 698
Brandt, M. E. (2002) · Emerging infectious diseases · doi:10.3201/eid0808.020059 · Cited by 646
White, T. C. (1997) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.41.7.1482 · Cited by 612
Perea, S., López-Ribot, J. L., Kirkpatrick, W. R., McAtee, R. K., Santillán, R. A., Martı́nez, M., Calabrese, D., Sanglard, D., & Patterson, T. F. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.10.2676-2684.2001 · Cited by 470
Antibiotic interactions that select against resistance
Chait, R., Craney, A., & Kishony, R. (2007) · Nature · doi:10.1038/nature05685 · Cited by 439
Coste, A., Turner, V., Ischer, F., Morschhäuser, J., Forche, A., Selmecki, A., Berman, J., Bille, J., & Sanglard, D. (2006) · Genetics · doi:10.1534/genetics.105.054767 · Cited by 385
Enjalbert, B., Smith, D. A., Cornell, M. J., Alam, I., Nicholls, S., Brown, A. J. P., & Quinn, J. (2006) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-06-0501 · Cited by 381
Cited by
Sorted by citations
Amphotericin primarily kills yeast by simply binding ergosterol
Gray, K. C., Palacios, D. S., Dailey, I., Endo, M. M., Uno, B. E., Wilcock, B. C., & Burke, M. D. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1117280109 · Cited by 608
Efflux-Mediated Antifungal Drug Resistance
Cannon, R. D., Lamping, E., Holmes, A. R., Niimi, K., Baret, P. V., Keniya, M. V., Tanabe, K., Niimi, M., Goffeau, A., & Monk, B. C. (2009) · Clinical Microbiology Reviews · doi:10.1128/cmr.00051-08 · Cited by 608
Self-citationRamage, G., Rajendran, R., Sherry, L., & Williams, C. (2012) · International Journal of Microbiology · doi:10.1155/2012/528521 · Cited by 583
Regulatory circuitry governing fungal development, drug resistance, and disease.
Shapiro, R. S., Robbins, N., & Cowen, L. E. (2011) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00045-10 · Cited by 576
Amphotericin forms an extramembranous and fungicidal sterol sponge
Anderson, T. M., Clay, M. C., Cioffi, A. G., Diaz, K. A., Hisao, G. S., Tuttle, M. D., Nieuwkoop, A. J., Comellas, G., Maryum, N., Wang, S., et al. (2014) · Nature Chemical Biology · doi:10.1038/nchembio.1496 · Cited by 528
Metadata
- Authors
- Cannon, R. D., Lamping, E., Holmes, A. R., Niimi, K., Tanabe, K., Niimi, M., & Monk, B. C.
- Affiliations
- University of Otago (NZ)
- National Institute of Infectious Diseases (JP)
- Venue
- Microbiology
- Publisher
- Microbiology Society
- Published
- 2007-10-01
- Volume
- 153
- Issue
- 10
- Pages
- 3211-3217
- ISSN
- 1350-0872 (ISSN-L)
- 1465-2080
- OpenAlex
- W2093997770
- Cited by
- 208
- References
- 46
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 4 · 2023: 9 · 2022: 3 · 2021: 17 · 2020: 10 · 2019: 16 · 2018: 13 · 2017: 15 · 2016: 13 · 2015: 9 · 2014: 19 · 2013: 19 · 2012: 10
- FWCI
- 1.34
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Microbiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Japan Health Sciences Foundation
- National Institutes of Health
- National Institute of Dental and Craniofacial Research (R01DE016885)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Fungal Plant Pathogen Control
- Keywords
- Candida albicans, antifungal resistance, drug tolerance, stress response, environmental stress, antifungal agents, stress response pathways, fungal pathogens
- MeSH terms
- Animals, Antifungal Agents, Candida albicans, Candidiasis, Humans, Drug Resistance, Fungal
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