The DOI matches its Crossref record.
Structure and function of the LysR-type transcriptional regulator (LTTR) family proteins
Abstract
The LysR family of transcriptional regulators represents the most abundant type of transcriptional regulator in the prokaryotic kingdom. Members of this family have a conserved structure with an N-terminal DNA-binding helix-turn-helix motif and a C-terminal co-inducer-binding domain. Despite considerable conservation both structurally and functionally, LysR-type transcriptional regulators (LTTRs) regulate a diverse set of genes, including those involved in virulence, metabolism, quorum sensing and motility. Numerous structural and transcriptional studies of members of the LTTR family are helping to unravel a compelling paradigm that has evolved from the original observations and conclusions that were made about this family of transcriptional regulators.
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Cited by
Bacterial ferrous iron transport: the Feo system
Lau, C. K. Y., Krewulak, K. D., & Vogel, H. J. (2016) · FEMS Microbiology Reviews · doi:10.1093/femsre/fuv049 · Cited by 428
Bervoets, I., & Charlier, D. (2019) · FEMS Microbiology Reviews · doi:10.1093/femsre/fuz001 · Cited by 180
Bacterial iron detoxification at the molecular level
Bradley, J. M., Svistunenko, D. A., Wilson, M. T., Hemmings, A. M., Moore, G. R., & Le Brun, N. E. (2020) · Journal of Biological Chemistry · doi:10.1074/jbc.rev120.007746 · Cited by 140
Toward a mechanistic understanding of Feo-mediated ferrous iron uptake
Sestok, A. E., Linkous, R. O., & Smith, A. T. (2018) · Metallomics · doi:10.1039/c8mt00097b · Cited by 96
Li, G., Shi, M., Zhao, S., Li, D., Long, Y., Yang, C., & Zhu, Y. (2020) · Gene · doi:10.1016/j.gene.2019.144197 · Cited by 18
Tailoring regulatory components for metabolic engineering in cyanobacteria
Bolay, P., Dodge, N., Janssen, K., Jensen, P. E., & Lindberg, P. (2024) · Physiologia Plantarum · doi:10.1111/ppl.14316 · Cited by 13
Brown, J. B., Lee, M. A., & Smith, A. T. (2022) · JBIC Journal of Biological Inorganic Chemistry · doi:10.1007/s00775-022-01945-4 · Cited by 5
Metadata
- Authors
- Maddocks, S. E., & Oyston, P. C. F.
- Venue
- Microbiology
- Publisher
- Microbiology Society
- Published
- 2008-12-01
- Volume
- 154
- Issue
- 12
- Pages
- 3609-3623
- ISSN
- 1350-0872 (ISSN-L)
- 1465-2080
- OpenAlex
- W1996577630
- Cited by
- 891
- References
- 0
- FWCI
- 19.34
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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