Automated model building and protein identification in cryo-EM maps
Jamali, Kiarash, Käll, Lukas, Zhang, Rui, Brown, Alan, Kimanius, Dari, Scheres, Sjors H.W.·2023·Nature
Cited by (653)
Items 101–200 of 653
- The N-terminal region of DNMT3A engages the nucleosome surface to aid chromatin recruitmentHannah Wapenaar, Gillian Clifford, Willow Rolls, Moira Pasquier, Hayden Burdett, Yujie Zhang, Gauri Deák, Juan Zou, Christos Spanos, Mark R D Taylor et al. · 2024 · EMBO Reports
- Evolutionary adaptations of doublet microtubules in trypanosomatid parasitesMatthew H. Doran, Qingwei Niu, Jianwei Zeng, Tom Beneke, James Amor Smith, Peter Ren, Sophia Fochler, Adrian Coscia, Johanna Louise Höög, Shimi Meleppattu et al. · 2025 · Science
- Cryo-EM structure and polar assembly of the PS2 S-layer of Corynebacterium glutamicumAdrià Sogues, Mike Sleutel, Julienne Petit, Daniela Megrian, Nicolas Bayan, Anne Marie Wehenkel, Han K. Remaut · 2025 · Proceedings of the National Academy of Sciences
- Cryo-EM structures of the E. coli Ton and Tol motor complexesHervé Celia, Istvan Botos, Rodolfo Ghirlando, Denis Duché, Bridgette M. Beach, Roland Lloubès, Susan K. Buchanan · 2025 · Nature Communications
- Germinal center–mediated broadening of B cell responses to SARS-CoV-2 booster immunizationSameer Kumar Malladi, Deepika Jaiswal, Baoling Ying, Wafaa B. Alsoussi, Tamarand L. Darling, Bernadeta Dadonaite, Alesandro Civljak, Stephen C. Horvath, Julian Q. Zhou, Wooseob Kim et al. · 2025 · Science Immunology
- RNA sample optimization for cryo-EM analysisXingyu Chen, Liu Wang, Jiahao Xie, Jakub Stanislaw Nowak, Bingnan Luo, Chong Zhang, Guowen Jia, Jian Zou, Dingming Huang, Sebastian Glatt et al. · 2024 · Nature Protocols
- Capturing ribosomal structures in cellular extracts with cryoPRISM: A purification-free cryoEM approach reveals novel structural statesMay, Mira B., Lopez-Perez, Gabriella S., Davis, Joseph H. · 2026 · Proceedings of the National Academy of Sciences
- The conserved HIV-1 spacer peptide 2 triggers matrix lattice maturation2025
- Structures of aberrant spliceosome intermediates on their way to disassemblySoni, Komal, Horvath, Attila, Dybkov, Olexandr, Schwan, Merlin, Trakansuebkul, Sasanan, Flemming, Dirk, Wild, Klemens, Urlaub, Henning, Fischer, Tamás, Sinning, Irmgard · 2025 · Nature Structural & Molecular Biology
- Advancing structure modeling from cryo-EM maps with deep learningShu Li, Genki Terashi, Zicong Zhang, Daisuke Kihara · 2025 · Biochemical Society Transactions
- Structural insights into the RNA-dependent RNA polymerase complexes from highly pathogenic Marburg and Ebola virusesGuobao Li, Tianjiao Du, Jiening Wang, Kun Jie, Zhuolu Ren, Xiaokang Zhang, Long Zhang, Shan Wu, Heng Ru · 2025 · Nature Communications
- Structure of an archaeal ribosome reveals a divergent active site and hibernation factorAmos J. Nissley, Yekaterina Shulgina, Roan W. Kivimae, Blake E. Downing, Petar I. Penev, Jillian F. Banfield, Dipti D. Nayak, Jamie H. D. Cate · 2025 · Nature Microbiology
- Delineating organizational principles of the endogenous L-A virus by cryo-EM and computational analysis of native cell extractsLisa Schmidt, Christian Tüting, Fotis L. Kyrilis, Farzad Hamdi, Dmitry A. Semchonok, Gerd Hause, Annette Meister, Christian H. Ihling, Pranav N. M. Shah, Milton T. Stubbs et al. · 2024 · Communications Biology
- Structural insights into the cooperative nucleosome recognition and chromatin opening by FOXA1 and GATA4Bing‐Rui Zhou, Hanqiao Feng, Furong Huang, Iris Zhu, Stephanie Portillo‐Ledesma, Dan Shi, Kenneth S. Zaret, Tamar Schlick A, David Landsman, Qianben Wang et al. · 2024 · Molecular Cell
- Cryo-EM structure of the CDK2-cyclin A-CDC25A complexRhianna J. Rowland, Svitlana Korolchuk, Marco Salamina, Natalie J. Tatum, James R. Ault, Sam Hart, J.P. Turkenburg, James N. Blaza, Martin E. M. Noble, Jane Endicott · 2024 · Nature Communications
- Structure of the turnover-ready state of an ancestral respiratory complex I2024
- Extending the reach of single-particle cryoEMArdan Patwardhan, Richard A. Henderson, Christopher J. Russo · 2025 · Current Opinion in Structural Biology
- Mystique, a broad host range Acinetobacter phage, reveals the impact of culturing conditions on phage isolation and infectivityEllinor Alseth, Carli Roush, Iris Irby, Mykhailo Kopylov, Daija Bobe, Monneh W Diggs, Kristy Nguyen, Huaijin Xu, Ingeborg Schmidt‐Krey, Anton V. Bryksin et al. · 2025 · PLoS Pathogens
- Lewy-MSA hybrid fold drives distinct neuronal α-synuclein pathologyMasahiro Enomoto, Iván Martínez-Valbuena, Shelley L. Forrest, Xiaoxiao Xu, Renato P. Munhoz, Jun Li, Ekaterina A. Rogaeva, Anthony Edward Lang, Gábor Géza Kovács · 2025 · Communications Biology
- Modeling cryo-EM structures in alternative states with AlphaFold2-based models and density-guided simulationsTatiana E. Shugaeva, Rebecca J. Howard, Nandan Haloi, Erik R. Lindahl · 2025 · Communications Chemistry
- Numerous rRNA molecules form the apicomplexan mitoribosome via repurposed protein and RNA elementsShikha Shikha, Victor Tobiasson, Mariana Ferreira Silva, Jana Ovciarikova, Dario Beraldi, Alexander Mühleip, Lilach Sheiner · 2025 · Nature Communications
- Confidence-guided cryo-EM map optimisation with LocScale-2.0Alok Bharadwaj, Reinier De Bruin, Arjen J. Jakobi · 2026 · Nature Communications
- Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7fAnastasiia Gusach, Yang Lee, Armin Nikpour Khoshgrudi, Elizaveta Mukhaleva, Ning Ma, Eline J. Koers, Qingchao Chen, Patricia C. Edwards, Fanglu Huang, Jonathan Kim et al. · 2024 · Nature Communications
- Conformational cycle of a protease-containing ABC transporter in lipid nanodiscs reveals the mechanism of cargo-protein couplingRuojing Zhang, Kevin L. Jagessar, Matthew Brownd, Adithya Polasa, Richard A. Stein, Mahmoud Moradi, Erkan Karakaş, Hassane S. Mchaourab · 2024 · Nature Communications
- Transport and InsP8 gating mechanisms of the human inorganic phosphate exporter XPR1Qinyu Zhu, Madeleine F. Yaggi, Nikolaus Jork, Henning Jacob Jessen, Melinda M. Diver · 2025 · Nature Communications
- Single-particle cryogenic electron microscopy structure determination for membrane proteinsChih-Ta Henry Chien, Merritt C. Maduke, Wah Chiu · 2025 · Current Opinion in Structural Biology
- Real-space heterogeneous reconstruction, refinement, and disentanglement of CryoEM conformational states with HetSIRENDavid Herreros, Carlos P. Mata, Chari M. Noddings, Deli Irene, James Krieger, David A. Agard, Ming‐Daw Tsai, Carlos Óscar S. Sorzano, J.M. Carazo · 2025 · Nature Communications
- MIC: A deep learning tool for assigning ions and waters in cryo-EM and crystal structuresLaura Shub, Wenjin Liu, Georgios Skiniotis, Michael J. Keiser, Michael J. Robertson · 2025 · Nature Communications
- Integrating diverse experimental information to assist protein complex structure prediction by GRASPYuhao Xie, Chengwei Zhang, Shimian Li, Xinyu Du, Yanjiao Lu, Min Wang, Yingtong Hu, Zhen‐Yu Chen, Sirui Liu, Yi Qin Gao · 2025 · Nature Methods
- CryoPROS: Correcting misalignment caused by preferred orientation using AI-generated auxiliary particlesZhang, Hui, Zheng, Dihan, Wu, Qiurong, Yan, Nieng, Peng, Han, Hu, Qi, Peng, Ying, Yan, Zhaofeng, Shi, Zuoqiang, Bao, Chenglong et al. · 2025 · Nature Communications
- Atomic models of the Toxoplasma cell invasion machineryJianwei Zeng, Yong Fu, Pengge Qian, Wei Huang, Qingwei Niu, Wandy L. Beatty, Alan Brown, L. David Sibley, Rui Zhang · 2025 · Nature Structural & Molecular Biology
- B cell imprinting in children impairs antibodies to the haemagglutinin stalkJiayi Sun, Gyunghee Jo, Chloe A. Troxell, Yanbin Fu, Robert Hoelzl, Huibin Lv, Hassanein H. Abozeid, Qi Wen Teo, Tossapol Pholcharee, Joshua J.C. McGrath et al. · 2026 · Nature
- Accurate magnification determination for cryoEM using goldJoshua L. Dickerson, Erin Leahy, Mathew James Peet, Katerina Naydenova, Christopher J. Russo · 2023 · Ultramicroscopy
- Machine learning approaches to cryoEM density modification differentially affect biomacromolecule and ligand density qualityRaymond F. Berkeley, B. Cook, Mark A. Herzik · 2024 · Frontiers in Molecular Biosciences
- Single particle cryo-EM map and model validation: It's not crystal clearGabriel C. Lander · 2024 · Current Opinion in Structural Biology
- Automated detection and de novo structure modeling of nucleic acids from cryo-EM mapsTao Li, Hong Cao, Jiahua He, Sheng‐You Huang · 2024 · Nature Communications
- Visualizing the modification landscape of the human 60S ribosomal subunit at close to atomic resolutionFranziska Wiechert, Anett Unbehaun, Thiemo Sprink, Helena Seibel, Jörg Bürger, J. Loerke, Thorsten Mielke, Christoph A. Diebolder, Magdalena Schacherl, Christian M. T. Spahn · 2024 · Nucleic Acids Research
- Bacterial pathogen deploys the iminosugar glycosyrin to manipulate plant glycobiologyNattapong Sanguankiattichai, Balakumaran Chandrasekar, Yuewen Sheng, Nathan J. Hardenbrook, Werner W. A. Tabak, Margit Drapal, Farnusch Kaschani, Clemens Grünwald‐Gruber, Daniel Krahn, Pierre Buscaill et al. · 2025 · Science
- Structures of the human adult muscle-type nicotinic receptor in resting and desensitized statesAnna Li, Ashley C. W. Pike, Richard G. Webster, Susan Maxwell, Wei Wei Liu, Gamma Chi, Jacqueline A. Palace, David Beeson, David Bryant Sauer, Yin Yao Dong · 2025 · Cell Reports
- Functional and epitope specific monoclonal antibody discovery directly from immune sera using cryo-EMJames A. Ferguson, Sai Sundar Rajan Raghavan, Garazi Peña Alzua, Disha Bhavsar, Jiachen Huang, Alesandra J. Rodriguez, Jonathan L. Torres, Maria Bottermann, Julianna Han, Florian Krammer et al. · 2025 · Science Advances
- The IFIT2–IFIT3 antiviral complex targets short 5’ untranslated regions on viral mRNAs for translation inhibitionDustin R. Glasner, Candace Todd, B. Cook, Agustina D’Urso, Shivani Khosla, Elena Estrada, Jaxon D. Wagner, Mason D. Bartels, Chuan-Tien Hung, Pierce W. Ford et al. · 2025 · Nature Microbiology
- Structural basis for molecular assembly of fucoxanthin chlorophyll a/c-binding proteins in a diatom photosystem I supercomplexKoji Kato, Yoshiki Nakajima, Jian Xing, Minoru Kumazawa, Haruya Ogawa, Jian‐Ren Shen, Kentaro Ifuku, Ryo Nagao · 2024 · eLife
- Proteome-wide in silico screening for human protein-protein interactionsErnst W. Schmid, Helen Zhu, Eunjin Ryu, Yang Lim, Agata Smogorzewska, Alan Brown, Johannes C. Walter · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- High-resolution structures of Myosin-IC reveal a unique actin-binding orientation, ADP release pathway, and power stroke trajectoryChavali, Sai Shashank, Carman, Peter J., Shuman, Henry, Ostap, E. Michael, Sindelar, Charles V. · 2025 · Proceedings of the National Academy of Sciences
- Structural basis of RECQL5-induced RNA polymerase II transcription braking and subsequent reactivationZhang, Luojia, Gordiyenko, Yuliya, Morgan, Tomos, Franco, Catarina, Tufegdžić Vidaković, Ana, Zhang, Suyang · 2025 · Nature Structural & Molecular Biology
- AI4Protein: transforming the future of protein designDequan Wang, Zheling Tan, Jin Gao, Shaoting Zhang, Jiaqi Shen, Yuming Lu · 2025 · Science China Life Sciences
- Dual Hydrophilic‐Hydrophobic Core Architecture in Soy Glycinin Amyloid Fibrils Revealed by Cryo‐EMSaiya Li, Shuangjian Li, Yijia Cheng, Yapeng Fang, Qin Cao, Yiping Cao · 2025 · Advanced Science
- Structural mechanism of the Retron-Eco7 anti-phage defense systemJunichiro Ishikawa, Kanta Yoneyama, Aa Haeruman Azam, Asuteka Nagao, Yoshihisa Mitsuda, Ren Nakazaki, Kotaro Chihara, Masahiro Hiraizumi, Keitaro Yamashita, Tsutomu Suzuki et al. · 2025 · Nature Communications
- Serine peptidase Vpr forms enzymatically active fibrils outside Bacillus bacteria revealed by cryo-EMYijia Cheng, Jianting Han, Meinai Song, Shuqin Zhang, Qin Cao · 2023 · Nature Communications
- Stabilization of the hexasome intermediate during histone exchange by yeast SWR1 complexAdam S. B. Jalal, Paul Girvan, Eugene Y. D. Chua, Lexin Liu, Shijie Wang, Elizabeth A. McCormack, Michael T. Skehan, Carol L. Knight, David Rueda, Dale B. Wigley · 2024 · Molecular Cell
- CryoSeek II: Cryo-EM analysis of glycofibrils from freshwater reveals well-structured glycans coating linear tetrapeptide repeatsTongtong Wang, Wenze Huang, Kui Xu, Yitong Sun, Qiangfeng Cliff Zhang, Chuangye Yan, Zhangqiang Li, Nieng Yan · 2024 · Proceedings of the National Academy of Sciences
- Predicting purification process fit of monoclonal antibodies using machine learningAndrew J. Maier, Minjeong Cha, Sean Burgess, Amy Wang, Carlos Cuellar, Soo Young Kim, Neeraja Sundar Rajan, Josephine Neyyan, R. SENGUPTA, Kelly O’Connor et al. · 2025 · mAbs
- The structure of Shigella virus Sf14 reveals the presence of two decoration proteins and two long tail fibersSundharraman Subramanian, Hailey R. Kerns, Samantha G. Braverman, Sarah M. Doore · 2025 · Communications Biology
- Building molecular model series from heterogeneous CryoEM structures using Gaussian mixture models and deep neural networksChen, Muyuan · 2025 · Communications Biology
- Structural basis of ubiquitin ligase Nedd4-2 autoinhibition and regulation by calcium and 14-3-3 proteinsMasa Janosev, Dalibor Košek, Andrej Tekel, Rohit Joshi, Karolína Honzejková, Pavel Pohl, Tomáš Obšil, Veronika Obšilová · 2025 · Nature Communications
- Intelligent Modeling for Deep Peak Shaving Oriented Thermal Power-Molten Salt Heat Storage Coupled System by Improved Mamba-2Ting Huang, Guolian Hou, Congzhi Huang, Fan Zhang, Qingwei Li · 2025 · IEEE Transactions on Systems Man and Cybernetics Systems
- Structure of the TXNL1-bound proteasomeJingjing Gao, Christopher Nardone, Matthew C. J. Yip, Haruka Chino, Xin Gu, Zachary Mirman, Michael J Rale, João A. Paulo, Stephen Joseph Elledge, Sichen Shao · 2025 · Nature Structural & Molecular Biology
- Evolutionarily diverse caveolins share a common structural framework built around amphipathic disksBing Han, Sarah M. Connolly, Darrin T. Schultz, Louis F.L. Wilson, Alican Gulsevin, Jens Meiler, Erkan Karakaş, Melanie D. Ohi, Anne K. Kenworthy · 2025 · The Journal of Cell Biology
- Measuring the selective packaging of RNA molecules by viral coat proteins in cellsAmineh Rastandeh, Nino Makasarashvili, Herman K. Dhaliwal, Sherry Baker, Sundharraman Subramanian, Daniel A. Villarreal, Elmer I. Gamez, Kristin N. Parent, Rees F. Garmann · 2025 · Proceedings of the National Academy of Sciences
- Clonotype-enriched somatic hypermutations drive affinity maturation of a public human antibody targeting an occluded sarbecovirus epitopeVishal N. Rao, Iden A. Sapse, Hallie Cohn, Duck-Kyun Yoo, Pei Tong, Jordan J. Clark, Bailey Bozarth, Yuexing Chen, Komal Srivastava, Gagandeep Singh et al. · 2025 · Cell Reports
- Donor strand complementation and calcium ion coordination drive the chaperone-free polymerization of archaeal cannulaeMike Sleutel, Ravi R. Sonani, Jessalyn Miller, Fengbin Wang, Andres Gonzalez Socorro, Yang Chen, Reece Martin, Borries Demeler, Michael J. Rudolph, Vikram Alva et al. · 2025 · Nature Communications
- Broadly potent anti-SARS-CoV-2 antibody shares 93% of epitope with ACE2 and provides full protection in monkeysCraig W. Fenwick, Priscilla Turelli, Yoan Duhoo, Kelvin Lau, Cécile Hérate, Romain Marlin, Myriam Lamrayah, Jérémy Campos, Line Esteves-Leuenberger, Alex Farina et al. · 2023 · Journal of Infection
- Mechanism of allosteric inhibition of RUVBL1-RUVBL2 ATPase by the small molecule CB-6644Carmen García‐Martín, Andrés López‐Perrote, Jasminka Boskovic, Óscar Llorca · 2024 · Cell Reports Physical Science
- Structural characterization of the ABC transporter DppABCDF in Escherichia coli reveals insights into dipeptide acquisitionPanpan Li, Manfeng Zhang, Yihua Huang · 2025 · PLoS Biology
- A conserved adaptor orchestrates co-secretion of synergistic type VI effectors in gut BacteroidotaWeixun Li, Shuaining Zheng, Xiaoning Xu, Jing J. He, Xuyao Jiao, Mingyu Wang, Wei Shau Hu, Shengying Li, Xianzhi Jiang, Bentley Lim et al. · 2025 · Cell Host & Microbe
- Structural basis for amyloid fibril assembly by the master cell-signaling regulator receptor-interacting protein kinase 1Paula Polonio, Jorge Pedro López-Alonso, Hanxing Jiang, Sara Andrés-Campos, Fátima C. Escobedo‐González, Gustavo A. Titaux‐Delgado, Iban Ubarretxena‐Belandia, Miguel Mompeán · 2025 · Nature Communications
- Structural landscape of activation, desensitization and inhibition in the human TRPM4 channelCelso M. Teixeira‐Duarte, Weizhong Zeng, Youxing Jiang · 2025 · Nature Structural & Molecular Biology
- Multimodal deep learning integration of cryo-EM and AlphaFold3 for high-accuracy protein structure determinationGyawali, Rajan, Dhakal, Ashwin, Cheng, Jianlin · 2025 · Communications Chemistry
- Effect of the S2’ site cleavage on SARS-CoV-2 spikeWei Kang Shi, G. M. Jonaid, Md. Golam Kibria, Jacob Allen, Hanqin Peng, Sophia Rits‐Volloch, Haisun Zhu, Shaowei Wang, Richard M. Walsh, Jianming Lu et al. · 2025 · Nature Communications
- Genetically diverse influenza antibodies highlight the role of IG germline gene variation and inform population-comprehensive vaccine strategiesAlexandra A. M. Fischer, Martin Corcoran, Philip J. M. Brouwer, Mark Chernyshev, Rebecca A. Gillespie, Andrea Nicoletto, Johannes R. Loeffler, James A. Ferguson, Ioannis Zygouras, Pradeepa Pushparaj et al. · 2026 · Immunity
- Helical reconstruction of VP39 reveals principles for baculovirus nucleocapsid assembly2024
- Structural insights into transmembrane helix S0 facilitated RyR1 channel gating by Ca2+/ATPRisheng Wei, Qiang Chen, Lei Zhang, Congcong Liu, Changcheng Yin, Changcheng Yin, Hongli Hu · 2025 · Nature Communications
- Identification of a seasonal influenza vaccine–induced broadly protective neuraminidase antibodyAnders Madsen, Nisreen M.A. Okba, Tossapol Pholcharee, Hanover C. Matz, Huibin Lv, Maria Ibanez Trullen, Julian Q. Zhou, Jackson S. Turner, Aaron J. Schmitz, Fangjie Han et al. · 2025 · The Journal of Experimental Medicine
- Mapping of human monoclonal antibody responses to XBB.1.5 COVID-19 monovalent vaccines: a B cell analysisRaianna Farhat Fantin, Jordan J. Clark, Hallie Cohn, Deepika Jaiswal, Bailey Bozarth, Vishal Rao, Alesandro Civljak, Igor Lobo, Jessica Nardulli, Komal Srivastava et al. · 2025 · The Lancet Microbe
- Targeted protein degradation in Escherichia coli using CLIPPERsMatylda Anna Izert, Maria Magdalena Klimecka, Anna Antosiewicz, Karol Wróblewski, Jakub Józef Kowalski, Katarzyna Bandyra, Tomasz K. Goral, Sebastian Kmiecik, Remigiusz Adam Serwa, Maria W. Górna · 2025 · EMBO Reports
- Cryo-EM of wild-type and mutant PMEL amyloid cores reveals structural mechanism of pigment dispersion syndromeHaruaki Yanagisawa, Harumi Arai, Tony Wang, Hideyuki Miyazawa, Masahide Kikkawa, Toshiyuki Oda · 2025 · Nature Communications
- A survey of downstream applications of evolutionary scale modeling protein language modelsQingyu Yang, Jiale Yu, Jie Zheng · 2025 · Quantitative Biology
- SND3 is the membrane insertase within a distinct SEC61 translocon complexTzu‐Jing Yang, Saumyak Mukherjee, Julian D. Langer, Gerhard Hummer, Melanie A. McDowell · 2025 · Nature Communications
- Atomic structure and in situ visualization of native PMEL lamellae in melanosomesMa Boyuan, Yuxuan Yao, Hui Dong, Linli Yang, Danni Li, Qinyue Zhao, Bo Sun, Yong Chen, Cong Liu, Dan Li · 2025 · Nature Communications
- Simultaneous occupancy of Cu C and Cu D in the ammonia monooxygenase active siteFrank J. Tucci, Madeline B. Ho, Aaron A.B. Turner, Lisa Y. Stein, Brian M. Hoffman, Amy C. Rosenzweig · 2025 · Chemical Science
- Advances in graph neural networks for alloy design and properties predictions: a reviewZhede Zhao, Tao Hu, Shuyu Bi, Dongwei Guan, Songzhe Xu, Chaoyue Chen, Weidong Xuan, Zhongming Ren · 2026 · Journal of Materials Informatics
- Molecular basis for anti-jumbo phage immunity by AVAST type 5Aswin Muralidharan, Ana Rita Costa, Desi Fierlier, Daan F. van den Berg, Halewijn van den Bossche, Adja Damba Zoumaro-Djayoon, Alicia Rodríguez-Molina, Martin Pabst, Martin Pačesa, Bruno E. Correia et al. · 2026 · Molecular Cell
- Computational biophysics meets cryo‐EM revolution in the search for the functional dynamics of biomolecular systemsMaurício G. S. Costa, Mert Gür, James Krieger, İvet Bahar · 2023 · Wiley Interdisciplinary Reviews Computational Molecular Science
- Defining bottlenecks and opportunities for Lassa virus neutralization by structural profiling of vaccine-induced polyclonal antibody responsesPhilip J. M. Brouwer, Hailee R. Perrett, Tim Beaumont, Haye Nijhuis, Sabine Kruijer, Judith A. Burger, Ilja Bontjer, Wen-Hsin Lee, James A. Ferguson, Martin Schauflinger et al. · 2024 · Cell Reports
- Structural variation of types IV-A1- and IV-A3-mediated CRISPR interferenceRimvydė Čepaitė, Nathalie Klein, Algirdas Mikšys, Sarah Camara-Wilpert, V. Ragožius, Fabienne Benz, A. Skorupskaitė, H. Becker, G. Žvejytė, Niklas Steube et al. · 2024 · Nature Communications
- Structurally heterogeneous ribosomes cooperate in protein synthesis in bacterial cellsKarla Helena-Bueno, Sophie Kopetschke, Sebastian Filbeck, Lewis I. Chan, Sonia Birsan, Arnaud Baslé, Maisie Hudson, Stefan Pfeffer, Chris H. Hill, Sergey V. Melnikov · 2025 · Nature Communications
- Cryo-EM structure of cyanopodophage A4 reveals a pentameric pre-ejectosome in the double-stabilized capsidPu Hou, Rui-Qian Zhou, Yong-Liang Jiang, Rong-Cheng Yu, Kang Du, Nanqin Gan, Fei Ke, Qi-Ya Zhang, Qiong Li, Cong‐Zhao Zhou · 2025 · Proceedings of the National Academy of Sciences
- Mechanisms of chromatin remodeling by the human Snf2-type ATPase SNF2HDeepshikha Malik, Ashish Deshmukh, Silvija Bilokapić, Mario Halić · 2025 · Cell Research
- A genome-scale drug discovery pipeline uncovers therapeutic targets and a unique p97 allosteric binding site in Schistosoma mansoni2025
- End-to-end cryo-EM complex structure determination with high accuracy and ultra-fast speedWang, Jue, Tan, Cheng, Gao, Zhangyang, Zhang, Guijun, Zhang, Yang, Li, Stan Z. · 2025 · Nature Machine Intelligence
- Structural biology in cellulo: Minding the gap between conceptualization and realizationFotis L. Kyrilis, Jason K. K. Low, Joel P. Mackay, Panagiotis L. Kastritis · 2024 · Current Opinion in Structural Biology
- Fitting Atomic Structures into Cryo-EM Maps by Coupling Deep Learning-Enhanced Map Processing with Global-Local OptimizationYaxian Cai, Ziying Zhang, Xiangyu Xu, Liang Xu, Yu Chen, Guijun Zhang, Xiaogen Zhou · 2025 · Journal of Chemical Information and Modeling
- Stepwise ATP translocation into the endoplasmic reticulum by human SLC35B1Ashutosh Gulati, Do-Hwan Ahn, Albert Suades, Yurie Hult, Gernot Wolf, So Iwata, Giulio Superti‐Furga, Norimichi Nomura, David Drew · 2025 · Nature
- Cryo-EM structure of the vault from human brain reveals symmetry mismatch at its capsSofia Lövestam, Sjors H. W. Scheres · 2025 · Structure
- The hook-like adaptor and cargo-binding (HAC) domain in the kinesin-2 tail enables adaptor assembly and cargo recognitionXuguang Jiang, Radostin Danev, Sotaro Ichinose, Baichun Niu, Sumio Ohtsuki, Haruaki Yanagisawa, Satoru Nagatoishi, Kouhei Tsumoto, Nobutaka Hirokawa, Masahide Kikkawa · 2025 · Science Advances
- EMProt improves structure determination from cryo-EM mapsTao Li, Ji Chen, Hao Li, Hong Cao, Sheng‐You Huang · 2025 · Nature Structural & Molecular Biology
- CSN5i-3 is an orthosteric molecular glue inhibitor of COP9 signalosomeHuigang Shi, Xiaorong Wang, Clinton Yu, Haibin Mao, Fenglong Jiao, Merav Braitbard, Ben Shor, Zhongsheng Zhang, Thomas Richard Hinds, Shiyun Cao et al. · 2026 · Nature
- Molecular basis of oocyte cytoplasmic lattice assemblyShuxian Liu, Yusong Liu, Junchao Xue, Zhenzhen Li, Yan Zhang, Bailun Li, Lidan Xu, Lili Li, Zhenzhen Yu, Hongtao Yu et al. · 2026 · Nature
- Anti–immune complex antibodies are elicited during repeated immunization with HIV Env immunogensSharidan Brown, Aleksandar Antanasijevic, Leigh M. Sewall, Daniel Montiel Garcia, James Ferguson, Philip J. M. Brouwer, Rogier W. Sanders, Andrew B. Ward · 2025 · Science Immunology
- Protein identification using Cryo-EM and artificial intelligence guides improved sample purificationKenneth D. Carr, Dane Evan Zambrano, Connor Weidle, Alex Goodson, Helen E. Eisenach, Harley Pyles, Alexis Courbet, Neil P. King, Andrew J. Borst · 2025 · Journal of Structural Biology X