The TNF Receptor Superfamily in Co-stimulating and Co-inhibitory Responses

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

The International IBD Genetics Consortium (IIBDGC), Jostins, L., Ripke, S., Weersma, R. K., Duerr, R. H., McGovern, D. P., Hui, K. Y., Lee, J. C., Philip Schumm, L., Sharma, Y., et al. (2012) · Nature · doi:10.1038/nature11582 · Cited by 4,722 · see citing works

The TNF and TNF Receptor Superfamilies

Locksley, R. M., Killeen, N., & Lenardo, M. J. (2001) · Cell · doi:10.1016/s0092-8674(01)00237-9 · Cited by 3,650 · see citing works

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

Franke, A., McGovern, D. P. B., Barrett, J. C., Wang, K., Radford-Smith, G. L., Ahmad, T., Lees, C. W., Balschun, T., Lee, J., Roberts, R., et al. (2010) · Nature Genetics · doi:10.1038/ng.717 · Cited by 2,520 · see citing works

Genetics of rheumatoid arthritis contributes to biology and drug discovery

the RACI consortium, Okada, Y., the GARNET consortium, Wu, D., Trynka, G., Raj, T., Terao, C., Ikari, K., Kochi, Y., Ohmura, K., et al. (2014) · Nature · doi:10.1038/nature12873 · Cited by 2,310 · see citing works

4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors

Long, A. H., Haso, W. M., Shern, J. F., Wanhainen, K. M., Murgai, M., Ingaramo, M., Smith, J. P., Walker, A. J., Kohler, M. E., Venkateshwara, V. R., et al. (2015) · Nature Medicine · doi:10.1038/nm.3838 · Cited by 1,815 · see citing works

Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance

Shimizu, J., Yamazaki, S., Takahashi, T., Ishida, Y., & Sakaguchi, S. (2002) · Nature Immunology · doi:10.1038/ni759 · Cited by 1,729 · see citing works

CD4+CD25+ Immunoregulatory T Cells

McHugh, R. S., Whitters, M. J., Piccirillo, C. A., Young, D. A., Shevach, E. M., Collins, M., & Byrne, M. C. (2002) · Immunity · doi:10.1016/s1074-7613(02)00280-7 · Cited by 1,395 · see citing works

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

Anderson, C. A., Boucher, G., Lees, C. W., Franke, A., D’Amato, M., Taylor, K. D., Lee, J. C., Goyette, P., Imielinski, M. B., Latiano, A., et al. (2011) · Nature Genetics · doi:10.1038/ng.764 · Cited by 1,312 · see citing works

Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells

Kawalekar, O. U., O’Connor, R. S., Fraietta, J. A., Guo, L., McGettigan, S. E., Posey, A. D., Patel, P. R., Guedan, S., Scholler, J., Keith, B., et al. (2016) · Immunity · doi:10.1016/j.immuni.2016.01.021 · Cited by 1,234 · see citing works

Genomewide Association Study of Leprosy

Zhang, F., Huang, W., Chen, S., Sun, L., Liu, H. D., Li, Y., Cui, Y., Yan, X., Yang, H., Yang, R., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0903753 · Cited by 1,037 · see citing works

Multiple common variants for celiac disease influencing immune gene expression

Dubois, P. C. A., Trynka, G., Franke, L., Hunt, K. A., Romanos, J., Curtotti, A., Zhernakova, A., Heap, G., Ádány, R., Aromaa, A. J., et al. (2010) · Nature Genetics · doi:10.1038/ng.543 · Cited by 1,026 · see citing works

TNFα promotes proliferation of oligodendrocyte progenitors and remyelination

Arnett, H. A., Mason, J., Marino, M., Suzuki, K., Matsushima, G. K., & Ting, J. P.-Y. (2001) · Nature Neuroscience · doi:10.1038/nn738 · Cited by 1,012 · see citing works

Regulation of tumour necrosis factor signalling: live or let die

Brenner, D., Blaser, H., & Mak, T. W. (2015) · Nature Reviews Immunology · doi:10.1038/nri3834 · Cited by 998 · see citing works

Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus

Han, J., Zheng, H., Cui, Y., Sun, L., Ye, D., Hu, Z. Q., Xu, J., Cai, Z., Huang, W., Zhao, G., et al. (2009) · Nature Genetics · doi:10.1038/ng.472 · Cited by 938 · see citing works

Cracking the BAFF code

Mackay, F., & Schneider, P. (2009) · Nature reviews. Immunology · doi:10.1038/nri2572 · Cited by 936 · see citing works

The molecular architecture of the TNF superfamily

Bodmer, J.-L., Schneider, P., & Tschopp, J. (2002) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(01)01995-8 · Cited by 918 · see citing works

Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer

Pitti, R. M., Marsters, S. A., Lawrence, D. A., Roy, M. A., Kischkel, F. C., Dowd, P., Huang, A. J. Y., Donahue, C. J., Sherwood, S. W., Baldwin, D. T., et al. (1998) · Nature · doi:10.1038/25387 · Cited by 775 · see citing works

The significance of OX40 and OX40L to T‐cell biology and immune disease

Croft, M., So, T., Duan, W., & Soroosh, P. (2009) · Immunological Reviews · doi:10.1111/j.1600-065x.2009.00766.x · Cited by 606 · see citing works

Anti-TNF therapy: past, present and future

Monaco, C. G., Nanchahal, J., Taylor, P. C., & Feldmann, M. (2014) · International Immunology · doi:10.1093/intimm/dxu102 · Cited by 580 · see citing works

The pharmacology of second-generation chimeric antigen receptors

van der Stegen, S. J. C., Hamieh, M., & Sadelain, M. (2015) · Nature Reviews Drug Discovery · doi:10.1038/nrd4597 · Cited by 561 · see citing works

Immune Modulation in Cancer with Antibodies

Page, D. B., Postow, M. A., Callahan, M. K., Allison, J. P., & Wolchok, J. D. (2013) · Annual Review of Medicine · doi:10.1146/annurev-med-092012-112807 · Cited by 516 · see citing works

Engagement of Glucocorticoid-Induced TNFR Family-Related Receptor on Effector T Cells by its Ligand Mediates Resistance to Suppression by CD4+CD25+ T Cells

Stephens, G. L., McHugh, R. S., Whitters, M. J., Young, D. A., Luxenberg, D. P., Carreno, B. M., Collins, M. A., & Shevach, E. M. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.8.5008 · Cited by 499 · see citing works

OX40 Is a Potent Immune-Stimulating Target in Late-Stage Cancer Patients

Curti, B. D., Kovacsovics-Bankowski, M., Morris, N. P., Walker, E., Chisholm, L., Floyd, K., Walker, J. M., Gonzalez, I. L., Meeuwsen, T. L., Fox, B. A., et al. (2013) · Cancer Research · doi:10.1158/0008-5472.can-12-4174 · Cited by 496 · see citing works

Clinical targeting of the TNF and TNFR superfamilies

Croft, M., Benedict, C. A., & Ware, C. F. (2013) · Nature Reviews Drug Discovery · doi:10.1038/nrd3930 · Cited by 457 · see citing works

The BAFF/APRIL system in SLE pathogenesis

Vincent, F. B., Morand, E. F., Schneider, P., & Mackay, F. (2014) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2014.33 · Cited by 449 · see citing works

TNF receptor 2 pathway: drug target for autoimmune diseases

Faustman, D., & Davis, M. (2010) · Nature Reviews Drug Discovery · doi:10.1038/nrd3030 · Cited by 446 · see citing works

CX3CR1+ mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22

Longman, R., Diehl, G. E., Victorio, D., Huh, J. R., Galan, C., Miraldi, E. R., Swaminath, A., Bonneau, R., Scherl, E., & Littman, D. (2014) · Journal of Experimental Medicine · doi:10.1084/jem.20140678 · Cited by 376 · see citing works

Chimeric Antigen Receptor Therapy for Cancer

Barrett, D. M., Singh, N., Porter, D. L., Grupp, S. A., & June, C. H. (2013) · Annual Review of Medicine · doi:10.1146/annurev-med-060512-150254 · Cited by 350 · see citing works

CD160 inhibits activation of human CD4+ T cells through interaction with herpesvirus entry mediator

Cai, G., Anumanthan, A., Brown, J. A., Greenfield, E. A., Zhu, B., & Freeman, G. J. (2008) · Nature Immunology · doi:10.1038/ni1554 · Cited by 346 · see citing works

Cutting Edge: Expression of TNFR2 Defines a Maximally Suppressive Subset of Mouse CD4+CD25+FoxP3+ T Regulatory Cells: Applicability to Tumor-Infiltrating T Regulatory Cells

Chen, X., Subleski, J. J., Kopf, H., Howard, O. M. Z., Männel, D. N., & Oppenheim, J. J. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.10.6467 · Cited by 336 · see citing works

Intrinsic Lymphotoxin-β Receptor Requirement for Homeostasis of Lymphoid Tissue Dendritic Cells

Kabashima, K., Banks, T. A., Ansel, K. M., Lu, T. T., Ware, C. F., & Cyster, J. G. (2005) · Immunity · doi:10.1016/j.immuni.2005.02.007 · Cited by 327 · see citing works

4-1BB-mediated immunotherapy of rheumatoid arthritis

Seo, S. K., Choi, J., Kim, Y. H., Kang, W., Park, H. Y., Suh, J. H., Choi, B. K., Vinay, D. S., & Kwon, B. S. (2004) · Nature Medicine · doi:10.1038/nm1107 · Cited by 326 · see citing works

Going viral: chimeric antigen receptor T‐cell therapy for hematological malignancies

Gill, S. I., & June, C. H. (2014) · Immunological Reviews · doi:10.1111/imr.12243 · Cited by 319 · see citing works

Hierarchy in somatic mutations arising during genomic evolution and progression of follicular lymphoma

Green, M. R., Gentles, A. J., Nair, R. V., Irish, J. M., Kihira, S., Liu, C. L., Kela, I., Hopmans, E. S., Myklebust, J. H., Ji, H. P., et al. (2013) · Blood · doi:10.1182/blood-2012-09-457283 · Cited by 318 · see citing works

Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease

Kugathasan, S., Baldassano, R. N., Bradfield, J. P., Abou‐Sleiman, P. M., Imielinski, M. B., Guthery, S. L., Cucchiara, S., Kim, C. E., Frackelton, E. C., Annaiah, K., et al. (2008) · Nature Genetics · doi:10.1038/ng.203 · Cited by 318 · see citing works

Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy

Grohmann, U., Volpi, C., Fallarino, F., Bozza, S., Bianchi, R., Vacca, C., Orabona, C., Belladonna, M. L., Ayroldi, E., Nocentini, G., et al. (2007) · Nature Medicine · doi:10.1038/nm1563 · Cited by 316 · see citing works

Expression, Localization, and Functional Activity of TL1A, a Novel Th1-Polarizing Cytokine in Inflammatory Bowel Disease

Bamias, G., Martin, C. T., Marini, M., Hoang, S. B., Mishina, M., Ross, W. G., Sachedina, M. A., Friel, C. M., Mize, J., Bickston, S. J., et al. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.9.4868 · Cited by 299 · see citing works

BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be partially reversed by vaccination

Derré, L., Rivals, J.-P., Jandus, C., Pastor, S., Rimoldi, D., Romero, P., Michielin, O., Olive, D., & Speiser, D. E. (2010) · Journal of Clinical Investigation · doi:10.1172/jci40070 · Cited by 295 · see citing works

TNFR2 Is Critical for the Stabilization of the CD4+Foxp3+ Regulatory T Cell Phenotype in the Inflammatory Environment

Chen, X., Wu, X., Zhou, Q., Howard, O. M. Z., Netea, M. G., & Oppenheim, J. J. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1202659 · Cited by 291 · see citing works

Costimulation via Glucocorticoid-Induced TNF Receptor in Both Conventional and CD25+ Regulatory CD4+ T Cells

Kanamaru, F., Youngnak‐Piboonratanakit, P., Hashiguchi, M., Nishioka, T., Takahashi, T., Sakaguchi, S., Ishikawa, I., & Azuma, M. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.12.7306 · Cited by 286 · see citing works

Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells

Mahmud, S. A., Manlove, L. S., Schmitz, H. M., Xing, Y., Wang, Y., Owen, D. L., Schenkel, J. M., Boomer, J. S., Green, J. M., Yagita∥, H., et al. (2014) · Nature Immunology · doi:10.1038/ni.2849 · Cited by 282 · see citing works

Clinical Experiences With Anti-CD137 and Anti-PD1 Therapeutic Antibodies

Ascierto, P. A., Simeone, E., Sznol, M., Fu, Y., & Melero, I. (2010) · Seminars in Oncology · doi:10.1053/j.seminoncol.2010.09.008 · Cited by 276 · see citing works

Genomic analysis of mycosis fungoides and Sézary syndrome identifies recurrent alterations in TNFR2

Ungewickell, A., Bhaduri, A., Rios, E. J., Reuter, J., Lee, C. S., Mah, A., Zehnder, A. M., Ohgami, R. S., Kulkarni, S., Armstrong, R. J., et al. (2015) · Nature Genetics · doi:10.1038/ng.3370 · Cited by 273 · see citing works

Genome-wide Association Study Identifies TNFSF15 and POU2AF1 as Susceptibility Loci for Primary Biliary Cirrhosis in the Japanese Population

Nakamura, M., Nishida, N., Kawashima, M., Aiba, Y., Tanaka, A., Yasunami, M., Nakamura, H., Komori, A., Nakamuta, M., Zeniya, M., et al. (2012) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2012.08.010 · Cited by 267 · see citing works

Nonredundant Function of Soluble LTα 3 Produced by Innate Lymphoid Cells in Intestinal Homeostasis

Kruglov, A., Grivennikov, S. I., Kuprash, D. V., Winsauer, C., Prepens, S., Seleznik, G. M., Eberl, G., Littman, D. R., Heikenwälder, M. F., Tumanov, A. V., et al. (2013) · Science · doi:10.1126/science.1243364 · Cited by 262 · see citing works

4-1BB Agonists: Multi-Potent Potentiators of Tumor Immunity

Bartkowiak, T., & Curran, M. A. (2015) · Frontiers in Oncology · doi:10.3389/fonc.2015.00117 · Cited by 256 · see citing works

Sustained Survivin Expression from OX40 Costimulatory Signals Drives T Cell Clonal Expansion

Song, J. J., So, T., Cheng, M. H.-Y., Tang, X., & Croft, M. (2005) · Immunity · doi:10.1016/j.immuni.2005.03.012 · Cited by 256 · see citing works

A coreceptor interaction between the CD28 and TNF receptor family members B and T lymphocyte attenuator and herpesvirus entry mediator

Gonzalez, L. C., Loyet, K. M., Calemine-Fenaux, J., Chauhan, V., Wranik, B. J., Ouyang, W., & Eaton, D. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409071102 · Cited by 252 · see citing works

OX40 Agonists and Combination Immunotherapy: Putting the Pedal to the Metal

Linch, S. N., McNamara, M. J., & Redmond, W. L. (2015) · Frontiers in Oncology · doi:10.3389/fonc.2015.00034 · Cited by 238 · see citing works

Constitutive Expression of LIGHT on T Cells Leads to Lymphocyte Activation, Inflammation, and Tissue Destruction

Shaikh, R. B., Santee, S. M., Granger, S. W., et al. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.167.11.6330 · Cited by 234 · see citing works

Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci

Folseraas, T., Melum, E., Rausch, P., Juran, B. D., Ellinghaus, E., Shiryaev, A., Laerdahl, J. K., Ellinghaus, D., Schramm, C., Weismüller, T. J., et al. (2012) · Journal of Hepatology · doi:10.1016/j.jhep.2012.03.031 · Cited by 232 · see citing works

TNF-α is critical for antitumor but not antiviral T cell immunity in mice

Calzascia, T., Pellegrini, M., Hall, H., Sabbagh, L., Ono, N., Elford, A. R., Mak, T. W., & Ohashi, P. S. (2007) · Journal of Clinical Investigation · doi:10.1172/jci32567 · Cited by 229 · see citing works

The TNF-Family Receptor DR3 is Essential for Diverse T Cell-Mediated Inflammatory Diseases

Meylan, F., Davidson, T. S., Kahle, E., Kinder, M., Acharya, K., Jankovic, D. L., Bundoc, V., Hodges, M. G., Shevach, E. M., Keane‐Myers, A., et al. (2008) · Immunity · doi:10.1016/j.immuni.2008.04.021 · Cited by 223 · see citing works

Slow Down and Survive: Enigmatic Immunoregulation by BTLA and HVEM

Murphy, T. L., & MURPHY, K. M. M. (2010) · Annual Review of Immunology · doi:10.1146/annurev-immunol-030409-101202 · Cited by 223 · see citing works

Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians

Yang, W., Tang, H., Zhang, Y., Tang, X., Zhang, J., Sun, L., Yang, J., Cui, Y., Zhang, L., Hirankarn, N., et al. (2012) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2012.11.018 · Cited by 221 · see citing works

TL1A–DR3 interaction regulates Th17 cell function and Th17-mediated autoimmune disease

Pappu, B. P., Borodovsky, A., Zheng, T. S., Yang, X. O., Wu, P., Dong, X., Weng, S., Browning, B., Scott, M. L., Ma, L., et al. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20071364 · Cited by 218 · see citing works

CD4+CD25+ regulatory T cells suppress allograft rejection mediated by memory CD8+ T cells via a CD30-dependent mechanism

Dai, Z., Li, Q., Wang, Y., Gao, G., Diggs, L., Tellides, G., & Lakkis, F. G. (2004) · Journal of Clinical Investigation · doi:10.1172/jci19727 · Cited by 210 · see citing works

PD-1 Blockade and OX40 Triggering Synergistically Protects against Tumor Growth in a Murine Model of Ovarian Cancer

Guo, Z., Wang, X., Cheng, D., Xia, Z., Luan, M., & Zhang, S. (2014) · PLoS ONE · doi:10.1371/journal.pone.0089350 · Cited by 207 · see citing works

Lymphotoxin Controls the IL-22 Protection Pathway in Gut Innate Lymphoid Cells during Mucosal Pathogen Challenge

Tumanov, A. V., Koroleva, E. P., Guo, X., Wang, Y., Kruglov, A., Nedospasov, S. A., & Fu, Y. (2011) · Cell Host & Microbe · doi:10.1016/j.chom.2011.06.002 · Cited by 199 · see citing works

Unconventional ligand activation of herpesvirus entry mediator signals cell survival

Cheung, T. C., Steinberg, M. W., Oborne, L. M., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0902115106 · Cited by 192 · see citing works

Acquired TNFRSF14 Mutations in Follicular Lymphoma Are Associated with Worse Prognosis

Cheung, K. J., Johnson, N. A., Affleck, J. G., et al. (2010) · Cancer Research · doi:10.1158/0008-5472.can-10-2460 · Cited by 186 · see citing works

Essential role of TNF receptor superfamily 25 (TNFRSF25) in the development of allergic lung inflammation

Fang, L., Adkins, B., Deyev, V. V., & Podack, E. R. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20072528 · Cited by 178 · see citing works

TNF superfamily member TL1A elicits type 2 innate lymphoid cells at mucosal barriers

Yu, X., Pappu, R., Ramirez-Carrozzi, V. R., et al. (2013) · Mucosal Immunology · doi:10.1038/mi.2013.92 · Cited by 173 · see citing works

CD30/TNF receptor-associated factor interaction: NF-kappa B activation and binding specificity.

Lee, S. Y., Lee, S. Y., Kandala, G., Liou, M.-L., Liou, H., & Choi, Y. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.18.9699 · Cited by 172 · see citing works

The tumor necrosis factor family member LIGHT is a target for asthmatic airway remodeling

Doherty, T. A., Soroosh, P., Khorram, N., Fukuyama, S., Rosenthal, P., Cho, J. Y., Norris, P. S., Choi, H., Scheu, S., Pfeffer, K., et al. (2011) · Nature Medicine · doi:10.1038/nm.2356 · Cited by 170 · see citing works

Combined Targeting of Costimulatory (OX40) and Coinhibitory (CTLA-4) Pathways Elicits Potent Effector T Cells Capable of Driving Robust Antitumor Immunity

Redmond, W. L., Linch, S. N., & Kasiewicz, M. J. (2013) · Cancer Immunology Research · doi:10.1158/2326-6066.cir-13-0031-t · Cited by 168 · see citing works

Glucocorticoid-induced tumor necrosis factor receptor–related protein co-stimulation facilitates tumor regression by inducing IL-9–producing helper T cells

Kim, I.-K., Kim, B.-S., Koh, C.-H., Seok, J.-W., Park, J.-S., Shin, K.-S., Bae, E.-A., Lee, G.-E., Jeon, H., Cho, J., et al. (2015) · Nature Medicine · doi:10.1038/nm.3922 · Cited by 167 · see citing works

CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB × NZW F1 mice

Foell, J. L., Strahotin, S., O’Neil, S. P., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci17662 · Cited by 166 · see citing works

Therapeutic Treg expansion in mice by TNFRSF25 prevents allergic lung inflammation

Schreiber, T. H., Wolf, D., Tsai, M. S., Chirinos, J., Deyev, V. V., Gonzalez, L. E., Malek, T. R., Levy, R. B., & Podack, E. R. (2010) · Journal of Clinical Investigation · doi:10.1172/jci42933 · Cited by 165 · see citing works

CD134 is a cellular receptor specific for human herpesvirus-6B entry

Tang, H., Serada, S., Kawabata, A., Ota, M., Hayashi, E., Naka, T., Yamanishi, K., & Mori, Y. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1305187110 · Cited by 164 · see citing works

The T Cell Costimulator TL1A Is Induced by FcγR Signaling in Human Monocytes and Dendritic Cells

Prehn, J., Thomas, L. S., Landers, C. J., Yu, Q., Michelsen, K. S., & Targan, S. R. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.7.4033 · Cited by 160 · see citing works

TNF Receptor 2 and Disease: Autoimmunity and Regenerative Medicine

Faustman, D. L., & Davis, M. (2013) · Frontiers in Immunology · doi:10.3389/fimmu.2013.00478 · Cited by 160 · see citing works

CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB × NZW F1 mice

Foell, J. L., Strahotin, S., O’Neil, S. P., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200317662 · Cited by 157 · see citing works

The TNF-family cytokine TL1A drives IL-13-dependent small intestinal inflammation

Meylan, F., Song, Y.-J., Fuss, I. J., Villarreal, S., Kahle, E., Malm, I.-J., Acharya, K., Ramos, H. L., Lo, L., Mentink‐Kane, M. M., et al. (2010) · Mucosal Immunology · doi:10.1038/mi.2010.67 · Cited by 154 · see citing works

T Cell Intrinsic Heterodimeric Complexes between HVEM and BTLA Determine Receptivity to the Surrounding Microenvironment

Cheung, T. C., Oborne, L. M., Steinberg, M. W., Macauley, M. G., Fukuyama, S., Sanjo, H., D'Souza, C., Norris, P. S., Pfeffer, K., MURPHY, K. M. M., et al. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0902490 · Cited by 153 · see citing works

Inherited human OX40 deficiency underlying classic Kaposi sarcoma of childhood

Byun, M., Ma, C. S., Akçay, A., Pedergnana, V., Palendira, U., Myoung, J., Avery, D. T., Liu, Y., Abhyankar, A., Lorenzo, L., et al. (2013) · The Journal of Experimental Medicine · doi:10.1084/jem.20130592 · Cited by 153 · see citing works

The TNF-family cytokine TL1A promotes allergic immunopathology through group 2 innate lymphoid cells

Meylan, F., Hawley, E., Barron, L., Barlow, J. L., Penumetcha, P. M., Pelletier, M., Sciumè, G., Richard, A. C., Hayes, E. T., Gómez‐Rodríguez, J., et al. (2013) · Mucosal Immunology · doi:10.1038/mi.2013.114 · Cited by 150 · see citing works

CD160 and PD-1 Co-Expression on HIV-Specific CD8 T Cells Defines a Subset with Advanced Dysfunction

Peretz, Y., He, Z., Shi, Y., Yassine‐Diab, B., Goulet, J.-P., Bordi, R., Filali‐Mouhim, A., Loubert, J.-B., Far, M. E., Dupuy, F. P., et al. (2012) · PLoS Pathogens · doi:10.1371/journal.ppat.1002840 · Cited by 148 · see citing works

Common and different genetic background for rheumatoid arthritis and coeliac disease

Coenen, M. J. H., Trynka, G., Heskamp, S., Franke, B., van Diemen, C. C., Smolonska, J., van Leeuwen, M., Brouwer, E., Boezen, M., Postma, D. S., et al. (2009) · Human Molecular Genetics · doi:10.1093/hmg/ddp365 · Cited by 147 · see citing works

Lymphotoxin-Mediated Crosstalk between B Cells and Splenic Stroma Promotes the Initial Type I Interferon Response to Cytomegalovirus

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A crucial role for HVEM and BTLA in preventing intestinal inflammation

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