The DOI matches its Crossref record; 191 of the 191 references it cites were found in a registry or an index.
Ribosome Profiling: Global Views of Translation
Open accessAbstract
The translation of messenger RNA (mRNA) into protein and the folding of the resulting protein into an active form are prerequisites for virtually every cellular process and represent the single largest investment of energy by cells. Ribosome profiling-based approaches have revolutionized our ability to monitor every step of protein synthesis in vivo, allowing one to measure the rate of protein synthesis across the proteome, annotate the protein coding capacity of genomes, monitor localized protein synthesis, and explore cotranslational folding and targeting. The rich and quantitative nature of ribosome profiling data provides an unprecedented opportunity to explore and model complex cellular processes. New analytical techniques and improved experimental protocols will provide a deeper understanding of the factors controlling translation speed and its impact on protein function and cell physiology as well as the role of ribosomal RNA and mRNA modifications in regulating translation.
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Cites
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Translational offsetting as a mode of estrogen receptor α‐dependent regulation of gene expression
Lorent, J., Kusnadi, E. P., van Hoef, V., Rebello, R. J., Leibovitch, M., Ristau, J., Chen, S., Lawrence, M. G., Szkop, K. J., Samreen, B., et al. (2019) · The EMBO Journal · doi:10.15252/embj.2018101323 · Cited by 46
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Metadata
- Authors
- Ingolia, N. T., Hussmann, J. A., & Weissman, J. S.
- Venue
- Cold Spring Harbor Perspectives in Biology
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2018-07-23
- Volume
- 11
- Issue
- 5
- Pages
- a032698
- ISSN
- 1943-0264 (ISSN-L)
- OpenAlex
- W2884275961
- Cited by
- 286
- References
- 191
- Type
- posted content
- Language
- en
- Open access
- green
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