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Cited by 506

The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.

Muscle stem cells in development, regeneration, and disease

Open access
Shi, Xiaozhong, Garry, Daniel J.·2006·Genes & Development

Abstract

Somatic stem cell populations participate in the development and regeneration of their host tissues. Skeletal muscle is capable of complete regeneration due to stem cells that reside in skeletal muscle and nonmuscle stem cell populations. However, in severe myopathic diseases such as Duchenne Muscular Dystrophy, this regenerative capacity is exhausted. In the present review, studies will be examined that focus on the origin, gene expression, and coordinated regulation of stem cell populations to highlight the regenerative capacity of skeletal muscle and emphasize the challenges for this field. Intense interest has focused on cell-based therapies for chronic, debilitating myopathic diseases. Future studies that enhance our understanding of stem cell biology and repair mechanisms will provide a platform for therapeutic applications directed toward these chronic, life-threatening diseases.

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Crossref · 10.1101/gad.1419406

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Metadata

Authors
Shi, X., & Garry, D. J.
Venue
Genes & Development
Published
2006-07-01
Volume
20
Issue
13
Pages
1692-1708
ISSN
  • 0890-9369 (ISSN-L)
  • 1549-5477
OpenAlex
W2112508321
Cited by
506
References
24
Type
posted content
Language
en
Open access
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CoChat. (2026). Citation check: Muscle stem cells in development, regeneration, and disease. https://app.cochat.ai/papers/10.1101/gad.1419406
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Shi, X., & Garry, D. J. (2006). Muscle stem cells in development, regeneration, and disease. Genes & Development. https://doi.org/10.1101/gad.1419406

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.