The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Two small regulatory RNAs establish opposing fates of a developmental axis
Open accessAbstract
Small RNAs are important regulators of gene expression. In maize, adaxial/abaxial (dorsoventral) leaf polarity is established by an abaxial gradient of microRNA166 (miR166), which spatially restricts the expression domain of class III homeodomain leucine zipper (HD-ZIPIII) transcription factors that specify adaxial/upper fate. Here, we show that leafbladeless1 encodes a key component in the trans-acting small interfering RNA (ta-siRNA) biogenesis pathway that acts on the adaxial side of developing leaves and demarcates the domains of hd-zipIII and miR166 accumulation. Our findings indicate that tasiR-ARF, a ta-siRNA, and miR166 establish opposing domains along the adaxial–abaxial axis, thus revealing a novel mechanism of pattern formation.
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Cites
Bartel (2004) · doi:10.1016/s0092-8674(04)00045-5 · Cited by 34,714
MicroRNAs AND THEIR REGULATORY ROLES IN PLANTS
Jones-Rhoades, M. W., Bartel, D. P., & Bartel, B. (2006) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.57.032905.105218 · Cited by 2,686
microRNA-Directed Phasing during Trans-Acting siRNA Biogenesis in Plants
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Radial Patterning of Arabidopsis Shoots by Class III HD-ZIP and KANADI Genes
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Role of PHABULOSA and PHAVOLUTA in determining radial patterning in shoots
McConnell, J. R., Emery, J., Eshed, Y., Bao, N., Bowman, J., & Barton, M. K. (2001) · Nature · doi:10.1038/35079635 · Cited by 1,104
MicroRNA functions in animal development and human disease
Alvarez-Garcia, I., & Miska, E. A. (2005) · Development · doi:10.1242/dev.02073 · Cited by 1,104
Mourrain, P., Béclin, C., Elmayan, T., Feuerbach, F., Godon, C., Morel, J.-B., Jouette, D., Lacombe, A.-M., Nikic, S., Picault, N., et al. (2000) · Cell · doi:10.1016/s0092-8674(00)80863-6 · Cited by 1,095
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Endogenous trans-Acting siRNAs Regulate the Accumulation of Arabidopsis mRNAs
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Cited by
Tian, F., Bradbury, P. J., Brown, P. J., Hung, H., Sun, Q., Flint-Garcia, S., Rocheford, T. R., McMullen, M. D., Holland, J. B., & Buckler, E. S. (2011) · Nature Genetics · doi:10.1038/ng.746 · Cited by 1,043
Pattern formation via small RNA mobility
Chitwood, D. H., Nogueira, F. T. S., Howell, M. D., Montgomery, T. A., Carrington, J. C., & Timmermans, M. C. P. (2009) · Genes & Development · doi:10.1101/gad.1770009 · Cited by 398
Self-citationTranscriptome-wide identification of microRNA targets in rice: Rice microRNA targets
Li, Y.-F., Zheng, Y., Addo-Quaye, C., Zhang, L., Saini, A., Jagadeeswaran, G., Axtell, M. J., Zhang, W., & Sunkar, R. (2010) · The Plant Journal · doi:10.1111/j.1365-313x.2010.04187.x · Cited by 396
Epidermis: the formation and functions of a fundamental plant tissue
Javelle, M., Vernoud, V., Rogowsky, P. M., & Ingram, G. C. (2011) · New Phytologist · doi:10.1111/j.1469-8137.2010.03514.x · Cited by 330
MicroRNA166 controls root and nodule development in Medicago truncatula
Boualem, A., Laporte, P., Jovanovic, M., Laffont, C., Plet, J., Combier, J., Niebel, A., Crespi, M., & Frugier, F. (2008) · The Plant Journal · doi:10.1111/j.1365-313x.2008.03448.x · Cited by 311
Metadata
- Authors
- Nogueira, F. T. S., Madi, S., Chitwood, D. H., Juarez, M. T., & Timmermans, M. C. P.
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2007-04-01
- Volume
- 21
- Issue
- 7
- Pages
- 750-755
- ISSN
- 0890-9369 (ISSN-L)
- 1549-5477
- OpenAlex
- W2000269678
- Cited by
- 273
- References
- 29
- Type
- posted content
- Language
- en
- Open access
- diamond
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- Nogueira, F. T. S., Madi, S., Chitwood, D. H., Juarez, M. T., & Timmermans, M. C. P. (2007). Two small regulatory RNAs establish opposing fates of a developmental axis. Genes & Development. https://doi.org/10.1101/gad.1528607
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