LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration

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LEDGF/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis

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MLL fusion proteins link transcriptional coactivators to previously active CpG-rich promoters

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An Allosteric Mechanism for Inhibiting HIV-1 Integrase with a Small Molecule

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NHEJ pathway is involved in post-integrational DNA repair due to Ku70 binding to HIV-1 integrase

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BET-independent MLV-based Vectors Target Away From Promoters and Regulatory Elements

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Nuclear protein LEDGF/p75 recognizes supercoiled DNA by a novel DNA-binding domain

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Insight in HIV Integration Site Selection Provides a Block-and-Lock Strategy for a Functional Cure of HIV Infection

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Factors that mold the nuclear landscape of HIV-1 integration

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Alternative Splicing and Caspase-Mediated Cleavage Generate Antagonistic Variants of the Stress Oncoprotein LEDGF/p75

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Novel near-infrared BiFC systems from a bacterial phytochrome for imaging protein interactions and drug evaluation under physiological conditions

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The Base Excision Repair Pathway Is Required for Efficient Lentivirus Integration

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B′-protein phosphatase 2A is a functional binding partner of delta-retroviral integrase

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Augmentation of Reverse Transcription by Integrase through an Interaction with Host Factor, SIP1/Gemin2 Is Critical for HIV-1 Infection

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The mechanism of H171T resistance reveals the importance of Nδ-protonated His171 for the binding of allosteric inhibitor BI-D to HIV-1 integrase

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A highly potent and safe pyrrolopyridine-based allosteric HIV-1 integrase inhibitor targeting host LEDGF/p75-integrase interaction site

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Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation

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The Competitive Interplay between Allosteric HIV-1 Integrase Inhibitor BI/D and LEDGF/p75 during the Early Stage of HIV-1 Replication Adversely Affects Inhibitor Potency

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Capsid–host interactions for HIV-1 ingress

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Mutations affecting interaction of integrase with TNPO3 do not prevent HIV-1 cDNA nuclear import

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New insights in the role of nucleoporins: A bridge leading to concerted steps from HIV-1 nuclear entry until integration

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Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase

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Measuring rapid hydrogen exchange in the homodimeric 36 kDa HIV‐1 integrase catalytic core domain

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Inhibitors of the Interactions between HIV‐1 IN and the Cofactor LEDGF/p75

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GS-9822, a Preclinical LEDGIN Candidate, Displays a Block-and-Lock Phenotype in Cell Culture

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