The intestinal stem cell

Barker, Nick, van de Wetering, Marc, Clevers, Hans·2008·Genes & Development

Cited by (621)

Items 101–200 of 621

  1. Amino Acids in Intestinal Physiology and Health
    Martín Beaumont, François Blachier · 2020 · Advances in experimental medicine and biology
  2. Dclk1-expressing tuft cells: critical modulators of the intestinal niche?
    Moritz A. Middelhoff, Christoph Benedikt Westphalen, Yoku Hayakawa, Kelley S. Yan, Michael David Gershon, Timothy Cragin Wang, Michael Quante · 2017 · American Journal of Physiology-Gastrointestinal and Liver Physiology
  3. Concise review: Clinical programs of stem cell therapies for liver and pancreas
    Giacomo Lanzoni, Tsunekazu Oikawa, Yunfang Wang, Cai-Bin Cui, Guido Carpino, Vincenzo Cardinale, David Allen Gerber, Mara Gabriel, Juan Domínguez‐Bendala, Mark E. Furth et al. · 2013 · Stem Cells
  4. Is irritable bowel syndrome an organic disorder?
    Magdy El‐Salhy · 2014 · World Journal of Gastroenterology
  5. Immortality and the base of multicellular life: Lessons from cnidarian stem cells
    Hiroshi Watanabe, Van Thanh Hoang, Robert Alexander Mättner, Thomas W. Holstein · 2009 · Seminars in Cell and Developmental Biology
  6. K-cells and Glucose-Dependent Insulinotropic Polypeptide in Health and Disease
    Young Min Cho, Timothy J. Kieffer · 2010 · Vitamins and hormones
  7. Tuberous sclerosis complex and Myc coordinate the growth and division ofDrosophilaintestinal stem cells
    Alla Amcheslavsky, Naoto Ito, Jin Jiang, Yicktung Tony Ip · 2011 · The Journal of Cell Biology
  8. ICRP Publication 131: Stem Cell Biology with Respect to Carcinogenesis Aspects of Radiological Protection
    Ohtsura Niwa, Mary Helen Barcellos‐Hoff, Ruth K. Globus, J.D. Harrison, J.H. Hendry, Peter Jacob, Michèle T. Martin, Thomas M. Seed, Jerry W. Shay, Michael D. Story et al. · 2015 · Annals of the ICRP
  9. Fate Restriction and Multipotency in Retinal Stem Cells
    Lázaro Centanin, Burkhard Höckendorf, Joachim Wittbrodt · 2011 · Cell stem cell
  10. Development of anticancer agents targeting the Wnt/β-catenin signaling.
    Xiangqian Zhang, Jijun Hao · 2015 · Europe PMC (PubMed Central)
  11. Apoptosis and cancer stem cells: Implications for apoptosis targeted therapy
    Frank A.E. Kruyt, Jan Jacob Schuringa · 2010 · Biochemical Pharmacology
  12. Brief Report: Dclk1 Deletion in Tuft Cells Results in Impaired Epithelial Repair After Radiation Injury
    Randal J. May, Dongfeng Qu, Nathaniel Weygant, Parthasarathy Chandrakesan, Naushad Ali, Stanley A. Lightfoot, Linheng Li, Sripathi M. Sureban, Courtney W. Houchen · 2013 · Stem Cells
  13. Space radiation triggers persistent stress response, increases senescent signaling, and decreases cell migration in mouse intestine
    Kumar, Santosh, Suman, Shubhankar, Fornace, Albert J., Datta, Kamal · 2018 · Proceedings of the National Academy of Sciences
  14. Role of Notch signaling in colon homeostasis and carcinogenesis
    Shingo Miyamoto, Daniel W. Rosenberg · 2011 · Cancer Science
  15. An Overview of Notch Signaling in Adult Tissue Renewal and Maintenance
    Chihiro Sato, Guojun Zhao, Ma. Xenia G. Ilagan · 2012 · Current Alzheimer Research
  16. Survivin is regulated by interleukin‐4 in colon cancer stem cells
    Anna Barbara Di Stefano, Flora Iovino, Ylenia Lombardo, Vincenzo Eterno, Thomas Höger, Francesco Dieli, Giorgio Stassi, Matilde Todaro · 2010 · Journal of Cellular Physiology
  17. The Role of Colorectal Cancer Stem Cells in Metastatic Disease and Therapeutic Response
    Eric C. Anderson, Crystal J. Hessman, Trevor G. Levin, Marcus M. Monroe, Melissa Hirose Wong · 2011 · Cancers
  18. Epithelial‐immune cell crosstalk for intestinal barrier homeostasis
    Yikun Yao, Wanjing Shang, Lingyu Bao, Zhaoyi Peng, Chuan Wu · 2024 · European Journal of Immunology
  19. Mesenchymal Stem Cell Therapy Alleviates Interstitial Cystitis by Activating Wnt Signaling Pathway
    Miho Song, Jisun Lim, Hwan Yeul Yu, Jun-Soo Park, Ji-Youn Chun, Jaeho Jeong, Jinbeom Heo, Hyun-Sook Kang, YongHwan Kim, Yong Mee Cho et al. · 2015 · Stem Cells and Development
  20. Heparin-binding EGF-like growth factor protects intestinal stem cells from injury in a rat model of necrotizing enterocolitis
    Chun‐Liang Chen, Xiaoyi Yu, Iyore James, Hong-yi Zhang, Jingyuan Yang, Andrei Radulescu, Yu Zhou, Gail Ellen Besner · 2011 · Laboratory Investigation
  21. The interplay between microbes and the immune response in inflammatory bowel disease
    Ashleigh Goethel, Kenneth Croitoru, Dana J. Philpott · 2018 · The Journal of Physiology
  22. Hepatic Progenitor Cells: An Update
    Tania Roskams, Aezam Katoonizadeh, Mina Komuta · 2010 · Clinics in Liver Disease
  23. Stem cell marker olfactomedin 4: critical appraisal of its characteristics and role in tumorigenesis
    Phulwinder K. Grover, Jennifer E. Hardingham, Adrian G. Cummins · 2010 · Cancer and Metastasis Reviews
  24. Normalizing genes for real-time polymerase chain reaction in epithelial and nonepithelial cells of mouse small intestine
    Fengchao Wang, Junping Wang, Dengqun Liu, Yongping Su · 2009 · Analytical Biochemistry
  25. Reactivation of NCAM1 Defines a Subpopulation of Human Adult Kidney Epithelial Cells with Clonogenic and Stem/Progenitor Properties
    Ella Buzhor, Dorit Omer, Orit Harari‐Steinberg, Zohar Dotan, Einav Vax, Sara Pri‐Chen, Sally Metsuyanim, Oren Pleniceanu, Ronald S. Goldstein, Benjamin Dekel · 2013 · American Journal Of Pathology
  26. Gastrointestinal neuroendocrine peptides/amines in inflammatory bowel disease
    Magdy El‐Salhy, Tefera Solomon, Trygve Hausken, Odd Helge Gilja, Jan Gunnar Hatlebakk · 2017 · World Journal of Gastroenterology
  27. Gut Microbial Influences on the Mammalian Intestinal Stem Cell Niche
    Bailey C. E. Peck, Michael T. Shanahan, Ajeet Pratap Singh, Praveen Sethupathy · 2017 · Stem Cells International
  28. Identification, isolation and characterization of human LGR5-positive colon adenoma cells
    Michael K. Dame, Durga Attili, Shannon D. McClintock, Priya H. Dedhia, Peter D. Ouillette, Olaf Hardt, Alana M. Chin, Xiang Xue, Julie Laliberté, Erica L. Katz et al. · 2018 · Development
  29. The Hippo–YAP/TAZ Signaling Pathway in Intestinal Self-Renewal and Regeneration After Injury
    Feihong Deng, Zengrong Wu, Fei Zou, Su Wang, Xuehong Wang · 2022 · Frontiers in Cell and Developmental Biology
  30. The Notch-2 Gene Is Regulated by Wnt Signaling in Cultured Colorectal Cancer Cells
    Jonas Ungerbäck, Nils Elander, John R. Grünberg, Mikael Sigvardsson, Peter Söderkvist · 2011 · PLoS ONE
  31. Evidence for multipotent endodermal stem/progenitor cell populations in human gallbladder
    Guido Carpino, Vincenzo Cardinale, Raffaele Gentile, Paolo Onori, R. Semeraro, Antonio Franchitto, Yunfang Wang, Daniela Bosco, Angelo Iossa, Chiara Napoletano et al. · 2014 · Journal of Hepatology
  32. Mesalamine Inhibits Epithelial β-Catenin Activation in Chronic Ulcerative Colitis
    Jeffrey B. Brown, Goo Lee, Elizabeth Z. Managlia, Gery R. Grimm, Ramanarao Dirisina, Tatiana Goretsky, Paul Cheresh, Nichole Renee Blatner, Khashayarsha Khazaie, Guang‐Yu Yang et al. · 2009 · Gastroenterology
  33. BCN057 induces intestinal stem cell repair and mitigates radiation-induced intestinal injury
    Payel Bhanja, Andrew J. Norris, Pooja Gupta-Saraf, Andrew C. Hoover, Subhrajit Saha · 2018 · Stem Cell Research & Therapy
  34. Genetic Disease and Therapy
    Theodore L. Roth, Alexander Marson · 2021 · Annual Review of Pathology Mechanisms of Disease
  35. Intestinal lineage commitment of embryonic stem cells
    Li Cao, Jason D. Gibson, Shingo Miyamoto, Vibhavari Sail, Rajeev Verma, Daniel W. Rosenberg, Craig E. Nelson, Charles A. Giardina · 2010 · Differentiation
  36. Calcium as a signal integrator in developing epithelial tissues
    Pavel Brodskiy, Jeremiah J. Zartman · 2018 · Physical Biology
  37. Zeb2 drives invasive and microbiota-dependent colon carcinoma
    Karolina Slowicka, Ιωάννα Πέττα, Gillian Blancke, Esther Hoste, Emilie Dumas, Mozes Sze, Hanna‐Kaisa Vikkula, Enrico Radaelli, Jody J. Haigh, Sven Jonckheere et al. · 2020 · Nature Cancer
  38. Regulation of intestinal stem cells in mammals and Drosophila
    Ping Wang, Xianyu Steven Hou · 2009 · Journal of Cellular Physiology
  39. In vitro generation of colonic epithelium from primary cells guided by microstructures
    Yuli Wang, Asad A. Ahmad, Christopher E. Sims, Scott T. Magness, Nancy L. Allbritton · 2014 · Lab on a Chip
  40. Insulin receptor isoform switching in intestinal stem cells, progenitors, differentiated lineages and tumors: evidence that IR-B limits proliferation
    Sarah F. Andres, James G. Simmons, Amanda T. Mah, M. Agostina Santoro, Laurianne Van Landeghem, P. Kay Lund · 2013 · Journal of Cell Science
  41. Changes in cellular mechanical properties during onset or progression of colorectal cancer
    Gabriele Ciasca, Massimiliano Papi, Eleonora Minelli, Valentina Palmieri, Marco De Spirito · 2016 · World Journal of Gastroenterology
  42. Intestinal epithelial cell-specific RARα depletion results in aberrant epithelial cell homeostasis and underdeveloped immune system
    Humberto B. Jijon, Lucía Suárez-López, Oscar E. Diaz, Srustidhar Das, Jaime De Calisto, Michael B. Yaffe, Mikaël J. Pittet, J. Rodrigo Mora, Yasmine Belkaid, Ramnik J. Xavier et al. · 2017 · Mucosal Immunology
  43. Colon Stem Cell and Crypt Dynamics Exposed by Cell Lineage Reconstruction
    Yitzhak Reizel, Noa Chapal-Ilani, Rivka Adar, Shalev Itzkovitz, Judith Elbaz, Yosef E. Maruvka, Elad Segev, Liran I. Shlush, Nava Dekel, Ehud Y. Shapiro · 2011 · PLoS Genetics
  44. Aryl hydrocarbon receptor utilises cellular zinc signals to maintain the gut epithelial barrier
    Xiuchuan Hu, Wenfeng Xiao, Yuxian Lei, Adam Green, X. Lee, Muralidhara Rao Maradana, Yajing Gao, Xueru Xie, Rui Wang, George Chennell et al. · 2023 · Nature Communications
  45. YY1 is indispensable for Lgr5 + intestinal stem cell renewal
    Ansu O. Perekatt, Michael J. Valdez, Melanie Davila, A. Hoffman, Edward M. Bonder, Nan Gao, Michael Paul Verzi · 2014 · Proceedings of the National Academy of Sciences
  46. Absolute requirement for STAT3 function in small-intestine crypt stem cell survival
    James R. Matthews, Owen James Sansom, Alan Richard Clarke · 2011 · Cell Death and Differentiation
  47. Mathematical model of adult stem cell regeneration with cross-talk between genetic and epigenetic regulation
    Jinzhi Lei, Simon A. Levin, Qing Hua Nie · 2014 · Proceedings of the National Academy of Sciences
  48. Rhythm of digestion: keeping time in the gastrointestinal tract
    Romke Bron, John B. Furness · 2009 · Clinical and Experimental Pharmacology and Physiology
  49. Lineage Tracing in the Intestinal Epithelium
    Nick Barker, Hans C. Clevers · 2010 · Current Protocols in Stem Cell Biology
  50. Lgr5 expression as stem cell marker in human gastric gland and its relatedness with other putative cancer stem cell markers
    Chen Wu, Yuanyuan Xie, Feng Gao, Yanan Wang, Ya-Wei Guo, Huanna Tian, Yanshuang Li, Wufang Fan · 2013 · Gene
  51. The adult Drosophila gastric and stomach organs are maintained by a multipotent stem cell pool at the foregut/midgut junction in the cardia (proventriculus)
    Shree Ram Singh, Kevin Xiankun Zeng, Grace Zhiyu Zheng, Xianyu Steven Hou · 2011 · Cell Cycle
  52. Proliferation State and Polo-Like Kinase1 Dependence of Tumorigenic Colon Cancer Cells
    Federica Francescangeli, Michele Patrizii, Michele Signore, G. Federici, Simone Di Franco, Alfredo Pagliuca, Marta Baiocchi, Mauro Biffoni, Lucia Ricci‐Vitiani, Matilde Todaro et al. · 2012 · Stem Cells
  53. Role of Label-Retaining Cells in Estrogen-Induced Endometrial Regeneration
    Rachel Chan, Tu’uhevaha J. Kaitu’u‐Lino, Caroline E. Gargett · 2011 · Reproductive Sciences
  54. Microbiota matures colonic epithelium through a coordinated induction of cell cycle-related proteins in gnotobiotic rat
    Claire Cherbuy, Edith Honvo‐Houeto, Aurélia Bruneau, Chantal Bridonneau, Camille Mayeur, Pierre‐Henri Duée, Philippe Langella, Muriel Thomas · 2010 · American Journal of Physiology-Gastrointestinal and Liver Physiology
  55. MET Signaling Mediates Intestinal Crypt-Villus Development, Regeneration, and Adenoma Formation and Is Promoted by Stem Cell CD44 Isoforms
    Sander P.J. Joosten, Jurrit Zeilstra, Harmen van Andel, R. Clinton D. Mijnals, Joost Zaunbrecher, Annet A. M. Duivenvoorden, Marc van de Wetering, Hans C. Clevers, Marcel Spaargaren, Steven T. Pals · 2017 · Gastroenterology
  56. The role of intestinal stem cell within gut homeostasis: Focusing on its interplay with gut microbiota and the regulating pathways
    Haoming Luo, Mingxing Li, Fang Wang, Yifei Yang, Qin Lin Wang, Yueshui Zhao, Fukuan Du, Yu Chen, Jing Shen, Qianyun Zhao et al. · 2022 · International Journal of Biological Sciences
  57. BCL9-2 Promotes Early Stages of Intestinal Tumor Progression
    Felix H. Brembeck, Maria Wiese, Nathalie Zatula, Tamara Grigoryan, Yiyang Dai, Johannes Fritzmann, Walter Birchmeier · 2011 · Gastroenterology
  58. Stem Cell Therapy in Inflammatory Bowel Disease: A Review of Achievements and Challenges
    Cheng‐mei Tian, Yuan Zhang, Meifeng Yang, Haoming Xu, Min‐zheng Zhu, Jun Yao, Lisheng Wang, Yujie Liang, Defeng Li · 2023 · Journal of Inflammation Research
  59. Succinate Modulates Intestinal Barrier Function and Inflammation Response in Pigs
    Xuan Li, Mingyu Mao, Yanan Zhang, Kaifan Yu, Weiyun Zhu · 2019 · Biomolecules
  60. Acute Overexpression of Myc in Intestinal Epithelium Recapitulates Some but Not All the Changes Elicited by Wnt/β-Catenin Pathway Activation
    Andrew J. Finch, Laura Soucek, Melissa R. Junttila, Lamorna Brown Swigart, Gérard I. Evan · 2009 · Molecular and Cellular Biology
  61. Abnormal differentiation of intestinal epithelium and intestinal barrier dysfunction in diabetic mice associated with depressed Notch/NICD transduction in Notch/Hes1 signal pathway
    Xiao‐Hui Min, Tao Yu, Qing Qing, Yuhong Yuan, Wa Zhong, Guang‐Cheng Chen, Li‐Na Zhao, Na Deng, Li-J Zhang, Qi‐Kui Chen · 2014 · Cell Biology International
  62. Probiotic and synbiotic therapy in the critically ill: State of the art
    James M. Davison, Paul Edmund Wischmeyer · 2018 · Nutrition
  63. Regulation of Gastrointestinal Mucosal Growth
    Jaladanki N. Rao, Jian‐Ying Wang · 2011
  64. Neoplasia Without Dysplasia: Lessons From Barrett Esophagus and Other Tubal Gut Neoplasms
    Robert Daniel Odze, Carlo C. Maley · 2010 · Archives of Pathology & Laboratory Medicine
  65. From Crypts to Cancer: A Holistic Perspective on Colorectal Carcinogenesis and Therapeutic Strategies
    Ehsan Gharib, Gilles A. Robichaud · 2024 · International Journal of Molecular Sciences
  66. Myb Permits Multilineage Airway Epithelial Cell Differentiation
    Jie-Hong Pan, Tracy L. Adair-Kirk, Anand C. Patel, Tao Huang, Nicholas S. Yozamp, Jian Xu, E. Premkumar Reddy, Derek E. Byers, Richard A. Pierce, Michael J. Holtzman et al. · 2014 · Stem Cells
  67. Colorectal Cancer: From the Genetic Model to Posttranscriptional Regulation by Noncoding RNAs
    María Antonia Lizarbe, Jorge Calle-Espinosa, Eva Fernández-Lizarbe, Sara Fernández‐Lizarbe, Miguel Ángel Robles-Ramos, Nieves Olmo, Javier Turnay · 2017 · BioMed Research International
  68. Spasmolytic polypeptide-expressing metaplasia (SPEM) in the gastric oxyntic mucosa does not arise from Lgr5-expressing cells
    Ki Taek Nam, Ryan L. O'Neal, Robert J. Coffey, Paul E. Finke, Nick Barker, James R. Goldenring · 2011 · Gut
  69. Intestinal stem cells acquire premature senescence and senescence associated secretory phenotype concurrent with persistent DNA damage after heavy ion radiation in mice
    Santosh Kumar, Shubhankar Suman, Albert J. Fornace, Kamal Datta · 2019 · Aging
  70. Polycomb repressive complex 2 impedes intestinal cell terminal differentiation
    Yannick D. Benoit, Manon Lepage, Taoufik Khalfaoui, Éric Tremblay, Nùria Basora, Julie C. Carrier, Lorraine J. Gudas, Jean‐François Beaulieu · 2012 · Journal of Cell Science
  71. Peyer’s patch myeloid cells infection by Listeria signals through gp38+ stromal cells and locks intestinal villus invasion
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  72. Dclk1+ small intestinal epithelial tuft cells display the hallmarks of quiescence and self-renewal
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  73. Stem cell therapy: an exercise in patience and prudence
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  74. Transcriptional Networks in Liver and Intestinal Development
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  75. A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts
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  76. Postnatal Deletion of Fat Storage-inducing Transmembrane Protein 2 (FIT2/FITM2) Causes Lethal Enteropathy
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  77. Lgr4 Gene Deficiency Increases Susceptibility and Severity of Dextran Sodium Sulfate-induced Inflammatory Bowel Disease in Mice
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  78. Determining Lineage Pathways from Cellular Barcoding Experiments
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  79. Optix defines a neuroepithelial compartment in the optic lobe of the Drosophila brain
    Katrina S. Gold, Andrea H. Brand · 2014 · Neural Development
  80. Transcriptional Networks and Signaling Pathways that Govern Vertebrate Intestinal Development
    Joan K. Heath · 2010 · Current topics in developmental biology/Current Topics in Developmental Biology
  81. Neighboring cells override 3D hydrogel matrix cues to drive human MSC quiescence
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  82. Protease‐activated receptor signaling in intestinal permeability regulation
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  83. Stem cells as potential therapeutic targets for inflammatory bowel disease
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  84. Gastric digestion of protein through pancreozyme action optimizes intestinal forms for absorption, mucin formation and villus integrity
    Edwin T. Moran · 2016 · Animal Feed Science and Technology
  85. Physical and functional interaction between A20 and ATG16L1-WD40 domain in the control of intestinal homeostasis
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  86. Epithelial Phosphatidylinositol-3-Kinase Signaling Is Required for β-Catenin Activation and Host Defense against Citrobacter rodentium Infection
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  87. Crypt Organoid Culture as an In Vitro Model in Drug Metabolism and Cytotoxicity Studies
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  88. TCF-1-mediated Wnt signaling regulates Paneth cell innate immune defense effectors HD-5 and -6: implications for Crohn's disease
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  89. Regulation of intestinal stem cell fate specification
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  90. Capture and 3D culture of colonic crypts and colonoids in a microarray platform
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  91. Deletion of intestinal epithelial insulin receptor attenuates high-fat diet-induced elevations in cholesterol and stem, enteroendocrine, and Paneth cell mRNAs
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  92. Germline Stem Cells and Their Regulation in the Nematode Caenorhabditis elegans
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  93. Intestinal stem cells and the colorectal cancer microenvironment
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  94. HIV enteropathy: HAART reduces HIV-induced stem cell hyperproliferation and crypt hypertrophy to normal in jejunal mucosa
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  95. Anti-Inflammatory and Tissue Regenerative Effects of Topical Treatment with Ozonated Olive Oil/Vitamin E Acetate in Balanitis Xerotica Obliterans
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  96. Heparan sulfate on intestinal epithelial cells plays a critical role in intestinal crypt homeostasis via Wnt/β-catenin signaling
    Shuji Yamamoto, Hiroshi Nakase, Minoru Matsuura, Yusuke Honzawa, Kayoko Matsumura, Norimitsu Uza, Yu Yamaguchi, Emiko Mizoguchi, Tsutomu Chiba · 2013 · American Journal of Physiology-Gastrointestinal and Liver Physiology
  97. Epigenetics in Intestinal Epithelial Cell Renewal
    Alireza Roostaee, Yannick D. Benoit, Salah Boudjadi, Jean‐François Beaulieu · 2016 · Journal of Cellular Physiology
  98. Spatio-Temporal Expression Profile of Stem Cell-Associated Gene LGR5 in the Intestine during Thyroid Hormone-Dependent Metamorphosis in Xenopus laevis
    Guihong Sun, Takashi Hasebe, Kenta Fujimoto, Rosemary G. Lu, Liezhen Fu, Hiroki Matsuda, Mitsuko Kajita, Atsuko Ishizuya‐Oka, Yun‐Bo Shi · 2010 · PLoS ONE
  99. The role and prognostic value of apoptosis in colorectal carcinoma
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  100. Therapeutic implications of colon cancer stem cells
    Eros Fabrizi · 2010 · World Journal of Gastroenterology