Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes

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Items 1,201–1,300 of 4,071

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3. The Relationship between DNA Replication and Human Genome Organization
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4. Regulation of p110δ PI 3-Kinase Gene Expression
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5. T-Bet Dependent Removal of Sin3A-Histone Deacetylase Complexes at the Ifng Locus Drives Th1 Differentiation
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6. Whole-Genome Sequencing Suggests Schizophrenia Risk Mechanisms in Humans with 22q11.2 Deletion Syndrome
   Daniele Merico, Mehdi Zarrei, Gregory Costain, Lucas Ogura, Babak Alipanahi, Matthew J. Gazzellone, Nancy J. Butcher, Bhooma Thiruvahindrapuram, Thomas Nalpathamkalam, Eva W.C. Chow et al. · 2015 · G3 Genes Genomes Genetics
7. Exploring 3D chromatin contacts in gene regulation: The evolution of approaches for the identification of functional enhancer-promoter interaction
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8. Intron size in mammals: complexity comes to terms with economy
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9. Animal Models in Biomedical Research
   Kirk J. Maurer, Fred William Quimby · 2015 · Elsevier eBooks
10. The (r)evolution of SINE versus LINE distributions in primate genomes: Sex chromosomes are important
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11. Deeply conserved chordate noncoding sequences preserve genome synteny but do not drive gene duplicate retention
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12. Understanding the constitutive presentation of MHC class I immunopeptidomes in primary tissues
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13. Gene regulation and the origins of human biological uniqueness
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14. Identification of expressed and conserved human noncoding RNAs
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15. Erasing Errors due to Alignment Ambiguity When Estimating Positive Selection
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16. Developmental transcriptome analysis of human erythropoiesis
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17. CLIPSeqTools—a novel bioinformatics CLIP-seq analysis suite
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18. Coding exon-structure aware realigner (CESAR) utilizes genome alignments for accurate comparative gene annotation
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19. The conservation and signatures of lincRNAs in Marek’s disease of chicken
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20. STarMir Tools for Prediction of microRNA Binding Sites
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21. Genomic distribution and estimation of nucleotide diversity in natural populations: perspectives from the collared flycatcher (Ficedula albicollis) genome
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22. Aminode: Identification of Evolutionary Constraints in the Human Proteome
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23. Ultraconserved elements (UCEs) illuminate the population genomics of a recent, high-latitude avian speciation event
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24. m6A Reader: Epitranscriptome Target Prediction and Functional Characterization of N6-Methyladenosine (m6A) Readers
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25. Human IRES Atlas: an integrative platform for studying IRES-driven translational regulation in humans
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26. Human-macaque comparisons illuminate variation in neutral substitution rates
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27. β-Catenin signaling regulates Foxa2 expression during endometrial hyperplasia formation
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28. Word-based characterization of promoters involved in human DNA repair pathways
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29. The opossum genome: Insights and opportunities from an alternative mammal
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30. Comparative analyses of super-enhancers reveal conserved elements in vertebrate genomes
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31. Systematic analysis and prediction of genes associated with monogenic disorders on human chromosome X
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32. Evaluating the Accuracy and Efficiency of Multiple Sequence Alignment Methods
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33. Perfect and imperfect views of ultraconserved sequences
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34. Systematic investigation of allelic regulatory activity of schizophrenia-associated common variants
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35. Identifying functional single nucleotide polymorphisms in the human CArGome
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36. Genetic Variation in Immune Regulation and DNA Repair Pathways and Stomach Cancer in China
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37. Identification of novel non-coding RNAs using profiles of short sequence reads from next generation sequencing data
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38. Identification of Biologically Relevant Enhancers in Human Erythroid Cells
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39. X Chromosomal Variation Is Associated with Slow Progression to AIDS in HIV-1-Infected Women
    Roman A. Siddiqui, Ulrike Sauermann, Janine Altmüller, Elfriede Fritzer, Michael Nothnagel, Nina Dalibor, Jacques Fellay, Franz‐Josef Kaup, Christiane Stahl‐Hennig, Peter Nürnberg et al. · 2009 · The American Journal of Human Genetics
40. A Novel Bayesian DNA Motif Comparison Method for Clustering and Retrieval
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41. Altered Chromatin Occupancy of Master Regulators Underlies Evolutionary Divergence in the Transcriptional Landscape of Erythroid Differentiation
    Jacob C. Ulirsch, Jessica N. Lacy, Xiuli An, Narla Mohandas, Tarjei Sigurd Mikkelsen, Vijay G. Sankaran · 2014 · PLoS Genetics
42. Human adaptation and population differentiation in the light of ancient genomes
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43. Systematic Analysis of Long Noncoding RNAs in the Senescence-accelerated Mouse Prone 8 Brain Using RNA Sequencing
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44. Genome annotation for clinical genomic diagnostics: strengths and weaknesses
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45. Light in the darkness: New perspective on lanternfish relationships and classification using genomic and morphological data
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46. Enrichment-Based Proteogenomics Identifies Microproteins, Missing Proteins, and Novel smORFs in Saccharomyces cerevisiae
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47. MISTIC: A prediction tool to reveal disease-relevant deleterious missense variants
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48. Bruton’s Tyrosine Kinase and Its Isoforms in Cancer
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49. The UCSC Genome Browser
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50. Mitochondrial DNA Sequence Variation Associated with Dementia and Cognitive Function in the Elderly
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51. Identification and analysis of miRNAs in human breast cancer and teratoma samples using deep sequencing
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52. Computational RNomics of Drosophilids
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53. Structure and function of the human genome
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54. Estimates of the Effect of Natural Selection on Protein-Coding Content
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55. Antagonistic Regulation of Apoptosis and Differentiation by the Cut Transcription Factor Represents a Tumor-Suppressing Mechanism in Drosophila
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56. The ATXN2-SH2B3 locus is associated with peripheral arterial disease: an electronic medical record-based genome-wide association study
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57. Accurate molecular diagnosis of phenylketonuria and tetrahydrobiopterin-deficient hyperphenylalaninemias using high-throughput targeted sequencing
    Daniel Trujillano, Belén Pérez, Justo González, Cristian Tornador, Rosa Navarrete, Geòrgia Escaramís, Stephan Ossowski, Lluı́s Armengol, Verónica Cornejo, Lourdes R. Desviat et al. · 2013 · European Journal of Human Genetics
58. Novel Exon of Mammalian ADAR2 Extends Open Reading Frame
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59. Functional classification of 15 million SNPs detected from diverse chicken populations
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60. A novel HSD17B10 mutation impairing the activities of the mitochondrial RNase P complex causes X-linked intractable epilepsy and neurodevelopmental regression
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61. Discovering the 3′ UTR-mediated regulation of alpha-synuclein
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62. Accelerated Evolution in Distinctive Species Reveals Candidate Elements for Clinically Relevant Traits, Including Mutation and Cancer Resistance
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63. miR-328 mediates a metabolic shift in colon cancer cells by targeting SLC2A1/GLUT1
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64. Comparative Transcriptomics Analyses across Species, Organs, and Developmental Stages Reveal Functionally Constrained lncRNAs
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65. What’s the target: understanding two decades of in silico microRNA-target prediction
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66. Extreme purifying selection against point mutations in the human genome
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67. Signatures of adaptive evolution within human non-coding sequence
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68. Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders
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69. Conserved effect of aging on DNA methylation and association with EZH2 polycomb protein in mice and humans
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70. Pan-cancer characterization of long non-coding RNA and DNA methylation mediated transcriptional dysregulation
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71. Whole genome sequencing delineates regulatory, copy number, and cryptic splice variants in early onset cardiomyopathy
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72. The genomic signature of trait-associated variants
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73. A single nucleotide polymorphism associated with isolated cleft lip and palate, thyroid cancer and hypothyroidism alters the activity of an oral epithelium and thyroid enhancer near FOXE1
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74. G-Boxes, Bigfoot Genes, and Environmental Response: Characterization of Intragenomic Conserved Noncoding Sequences inArabidopsis
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75. Psoriasis drug development and GWAS interpretation through in silico analysis of transcription factor binding sites
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76. Hundreds of conserved non-coding genomic regions are independently lost in mammals
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77. Evaluating the Evidence for Transmission Distortion in Human Pedigrees
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78. A novel reannotation strategy for dissecting DNA methylation patterns of human long intergenic non-coding RNAs in cancers
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79. Big Genomes Facilitate the Comparative Identification of Regulatory Elements
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80. Dendritic targeting of short and long 3′ UTR BDNF mRNA is regulated by BDNF or NT-3 and distinct sets of RNA-binding proteins
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81. Congenital dilated cardiomyopathy caused by biallelic mutations in Filamin C
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82. Mining for Small Translated ORFs
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83. Taking a bite out of nutrition and arbovirus infection
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84. Systematic Analysis of Long Non-Coding RNAs and mRNAs in the Ovaries of Duroc Pigs During Different Follicular Stages Using RNA Sequencing
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85. Epigenomic analysis reveals DNA motifs regulating histone modifications in human and mouse
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86. Functional characterization of CHEK2 variants in a Saccharomyces cerevisiae system
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87. Gene expression differences between matched pairs of ovarian cancer patient tumors and patient-derived xenografts
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88. A retrocopy of a gene can functionally displace the source gene in evolution
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89. DroSpeGe: rapid access database for new Drosophila species genomes
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90. Evolution of transcription factor binding through sequence variations and turnover of binding sites
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91. High-resolution annotation of the mouse preimplantation embryo transcriptome using long-read sequencing
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92. Integrated Analysis of Dysregulated lncRNA Expression in Fetal Cardiac Tissues with Ventricular Septal Defect
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93. Identifying and mapping cell-type-specific chromatin programming of gene expression
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94. RNAi Screen Indicates Widespread Biological Function for Human Natural Antisense Transcripts
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95. Screening of human SNP database identifies recoding sites of A-to-I RNA editing
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96. Finding regulatory DNA motifs using alignment-free evolutionary conservation information
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97. Genome-Wide Detection and Analysis of Multifunctional Genes
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98. Determining the Effect of Natural Selection on Linked Neutral Divergence across Species
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99. Whole exome sequencing identification of novel candidate genes in patients with proliferative diabetic retinopathy
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100. Mining for missed sORF-encoded peptides
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