The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Genomic Analysis of the Nitrate Response Using a Nitrate Reductase-Null Mutant of Arabidopsis
Open accessAbstract
A nitrate reductase (NR)-null mutant of Arabidopsis was constructed that had a deletion of the major NR gene NIA2 and an insertion in the NIA1 NR gene. This mutant had no detectable NR activity and could not use nitrate as the sole nitrogen source. Starch mobilization was not induced by nitrate in this mutant but was induced by ammonium, indicating that nitrate was not the signal for this process. Microarray analysis of gene expression revealed that 595 genes responded to nitrate (5 mm nitrate for 2 h) in both wild-type and mutant plants. This group of genes was overrepresented most significantly in the functional categories of energy, metabolism, and glycolysis and gluconeogenesis. Because the nitrate response of these genes was NR independent, nitrate and not a downstream metabolite served as the signal. The microarray analysis also revealed that shoots can be as responsive to nitrate as roots, yet there was substantial organ specificity to the nitrate response.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
SOLÓRZANO, L. (1969) · Limnology and Oceanography · doi:10.4319/lo.1969.14.5.0799 · Cited by 3,501
DREW, M. C. (1975) · New Phytologist · doi:10.1111/j.1469-8137.1975.tb01409.x · Cited by 929
Dual pathways for regulation of root branching by nitrate
Zhang, H., Jennings, A., Barlow, P. W., & Forde, B. G. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.11.6529 · Cited by 700
Wang, R., Okamoto, M., Xing, X., & Crawford, N. M. (2003) · Plant Physiology · doi:10.1104/pp.103.021253 · Cited by 678
Self-citation[32] Metabolite levels in specific cells and subcellular compartments of plant leaves
Stitt, M., Lilley, R. M., Gerhardt, R., & Heldt, H. W. (1989) · Methods in Enzymology · doi:10.1016/0076-6879(89)74035-0 · Cited by 676
Miyawaki, K., Matsumoto‐Kitano, M., & Kakimoto, T. (2004) · The Plant Journal · doi:10.1046/j.1365-313x.2003.01945.x · Cited by 662
Automated analysis for nitrate by hydrazine reduction
Kamphake, L. J., Hannah, S. A., & Cohen, J. M. (1967) · Water Research · doi:10.1016/0043-1354(67)90011-5 · Cited by 640
Steps towards an integrated view of nitrogen metabolism
Stitt, M. (2002) · Journal of Experimental Botany · doi:10.1093/jexbot/53.370.959 · Cited by 625
Nitrate Acts as a Signal to Induce Organic Acid Metabolism and Repress Starch Metabolism in Tobacco.
Scheible, W. R., Gonzalez-Fontes, A., Lauerer, M., Muller-Rober, B., Caboche, M., & Stitt, M. (1997) · The Plant Cell · doi:10.1105/tpc.9.5.783 · Cited by 600
Nitrate regulation of metabolism and growth
Stitt, M. (1999) · Current Opinion in Plant Biology · doi:10.1016/s1369-5266(99)80033-8 · Cited by 587
Cited by
Signal integration in the control of shoot branching
Domagalska, M. A., & Leyser, O. (2011) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3088 · Cited by 835
Arabidopsis NIN-like transcription factors have a central role in nitrate signalling
Konishi, M., & Yanagisawa, S. (2013) · Nature Communications · doi:10.1038/ncomms2621 · Cited by 470
Multiple mechanisms of nitrate sensing by Arabidopsis nitrate transceptor NRT1.1
Bouguyon, E., Brun, F., Meynard, D., Kubeš, M., Pervent, M., Leran, S., Lacombe, B., Krouk, G., Guiderdoni, E., Zažímalová, E., et al. (2015) · Nature Plants · doi:10.1038/nplants.2015.15 · Cited by 353
de Jong, M., George, G., Ongaro, V., Williamson, L., Willetts, B., Ljung, K., McCulloch, H., & Leyser, O. (2014) · Plant Physiology · doi:10.1104/pp.114.242388 · Cited by 138
Dynamic changes in mRNA nucleocytoplasmic localization in the nitrate response of Arabidopsis roots
(2024) · doi:10.1111/pce.15018 · Cited by 9
Metadata
- Authors
- Wang, R., Tischner, R., Gutiérrez, R. A., Hoffman, M., Xing, X., Chen, M., Coruzzi, G., & Crawford, N. M.
- Venue
- Plant Physiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2004-09-01
- Volume
- 136
- Issue
- 1
- Pages
- 2512-2522
- ISSN
- 0032-0889 (ISSN-L)
- 1532-2548
- OpenAlex
- W2110637407
- Cited by
- 448
- References
- 28
- FWCI
- 15.00
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Genomic Analysis of the Nitrate Response Using a Nitrate Reductase-Null Mutant of Arabidopsis. https://app.cochat.ai/papers/10.1104/pp.104.044610
- The paper
- Wang, R., Tischner, R., Gutiérrez, R. A., Hoffman, M., Xing, X., Chen, M., Coruzzi, G., & Crawford, N. M. (2004). Genomic Analysis of the Nitrate Response Using a Nitrate Reductase-Null Mutant of Arabidopsis. Plant Physiology. https://doi.org/10.1104/pp.104.044610
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
