The DOI matches its Crossref record; 81 of the 81 references it cites were found in a registry or an index.
Functional Analysis of a Predicted Flavonol Synthase Gene Family in Arabidopsis
Open accessAbstract
The genome of Arabidopsis (Arabidopsis thaliana) contains five sequences with high similarity to FLAVONOL SYNTHASE1 (AtFLS1), a previously characterized flavonol synthase gene that plays a central role in flavonoid metabolism. This apparent redundancy suggests the possibility that Arabidopsis uses multiple isoforms of FLS with different substrate specificities to mediate the production of the flavonols, quercetin and kaempferol, in a tissue-specific and inducible manner. However, biochemical and genetic analysis of the six AtFLS sequences indicates that, although several of the members are expressed, only AtFLS1 encodes a catalytically competent protein. AtFLS1 also appears to be the only member of this group that influences flavonoid levels and the root gravitropic response in seedlings under nonstressed conditions. This study showed that the other expressed AtFLS sequences have tissue- and cell type-specific promoter activities that overlap with those of AtFLS1 and encode proteins that interact with other flavonoid enzymes in yeast two-hybrid assays. Thus, it is possible that these “pseudogenes” have alternative, noncatalytic functions that have not yet been uncovered.
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Cites
Floral dip: a simplified method forAgrobacterium‐mediated transformation ofArabidopsis thaliana
Clough, S. J., & Bent, A. F. (1998) · The Plant Journal · doi:10.1046/j.1365-313x.1998.00343.x · Cited by 21,934
Analysis of the genome sequence of the flowering plant Arabidopsis thaliana
Initiative, T. A. G. (2000) · Nature · doi:10.1038/35048692 · Cited by 9,301
Genome-Wide Insertional Mutagenesis of Arabidopsis thaliana
Alonso, J. M., Stepanova, A. N., Leisse, T. J., Kim, C. J., Chen, H., Shinn, P., Stevenson, D. K., Zimmerman, J., Barajas, P., Cheuk, R., et al. (2003) · Science · doi:10.1126/science.1086391 · Cited by 5,102
Advances in flavonoid research since 1992
Harborne, J. B., & Williams, C. A. (2000) · Phytochemistry · doi:10.1016/s0031-9422(00)00235-1 · Cited by 3,956
The biochemistry and medical significance of the flavonoids
Havsteen, B. H. (2002) · Pharmacology & Therapeutics · doi:10.1016/s0163-7258(02)00298-x · Cited by 2,672
A simple and rapid method for the preparation of plant genomic DNA for PCR analysis
Edwards, K., Johnstone, C., & Thompson, C. (1991) · Nucleic Acids Research · doi:10.1093/nar/19.6.1349 · Cited by 2,615
GENEVESTIGATOR. Arabidopsis Microarray Database and Analysis Toolbox
Zimmermann, P., Hirsch-Hoffmann, M., Hennig, L., & Gruissem, W. (2004) · Plant Physiology · doi:10.1104/pp.104.046367 · Cited by 2,462
Biosynthesis of flavonoids and effects of stress
Winkel-Shirley, B. (2002) · Current Opinion in Plant Biology · doi:10.1016/s1369-5266(02)00256-x · Cited by 1,885
Differential Gene Expression in Response to Mechanical Wounding and Insect Feeding in Arabidopsis
Reymond, P., Weber, H., Damond, M., & Farmer, E. E. (2000) · The Plant Cell · doi:10.1105/tpc.12.5.707 · Cited by 1,227
Stracke, R., Ishihara, H., Huep, G., Barsch, A., Mehrtens, F., Niehaus, K., & Weisshaar, B. (2007) · The Plant Journal · doi:10.1111/j.1365-313x.2007.03078.x · Cited by 1,182
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Multiple functional roles of flavonoids in photoprotection
Agati, G., & Tattini, M. (2010) · New Phytologist · doi:10.1111/j.1469-8137.2010.03269.x · Cited by 803
Martens, S., Preuß, A., & Matern, U. (2010) · Phytochemistry · doi:10.1016/j.phytochem.2010.04.016 · Cited by 258
Soubeyrand, E., Johnson, T. S., Latimer, S., Block, A., Kim, J., Colquhoun, T. A., Butelli, E., Martin, C., Wilson, M. A., & Basset, G. J. (2018) · The Plant Cell · doi:10.1105/tpc.18.00688 · Cited by 61
Metadata
- Authors
- Owens, D. K., Alerding, A. B., Crosby, K. C., Bandara, A. B., Westwood, J. H., & Winkel, B. S. J.
- Venue
- Plant Physiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2008-05-08
- Volume
- 147
- Issue
- 3
- Pages
- 1046-1061
- ISSN
- 0032-0889 (ISSN-L)
- 1532-2548
- OpenAlex
- W2125950656
- Cited by
- 320
- References
- 81
- FWCI
- 3.97
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Owens, D. K., Alerding, A. B., Crosby, K. C., Bandara, A. B., Westwood, J. H., & Winkel, B. S. J. (2008). Functional Analysis of a Predicted Flavonol Synthase Gene Family in Arabidopsis. Plant Physiology. https://doi.org/10.1104/pp.108.117457
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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