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Cited by 417

The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.

The CLAVATA1 Receptor-like Kinase Requires CLAVATA3 for Its Assembly into a Signaling Complex That Includes KAPP and a Rho-Related Protein

Open access
Trotochaud, Amy E., Hao, Tong, Wu, Guang, Yang, Zhenbiao, Clark, Steven E.·1999·The Plant Cell
DOI 10.1105/tpc.11.3.393
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Abstract

The CLAVATA1 (CLV1) and CLAVATA3 (CLV3) genes are required to maintain the balance between cell proliferation and organ formation at the Arabidopsis shoot and flower meristems. CLV1 encodes a receptor-like protein kinase. We have found that CLV1 is present in two protein complexes in vivo. One is approximately 185 kD, and the other is approximately 450 kD. In each complex, CLV1 is part of a disulfide-linked multimer of approximately 185 kD. The 450-kD complex contains the protein phosphatase KAPP, which is a negative regulator of CLV1 signaling, and a Rho GTPase-related protein. In clv1 and clv3 mutants, CLV1 is found primarily in the 185-kD complex. We propose that CLV1 is present as an inactive disulfide-linked heterodimer and that CLV3 functions to promote the assembly of the active 450-kD complex, which then relays signal transduction through a Rho GTPase.

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Metadata

Authors
Trotochaud, A. E., Hao, T., Wu, G., Yang, Z., & Clark, S. E.
Venue
The Plant Cell
Publisher
Oxford University Press (OUP)
Published
1999-03
Volume
11
Issue
3
Pages
393-405
ISSN
  • 1040-4651 (ISSN-L)
  • 1532-298X
DOI
10.1105/tpc.11.3.393
OpenAlex
W2170279909
Cited by
417
References
33
FWCI
54.32
Type
journal article
Language
en
Open access
green

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