Cited by 35Hemodynamic Monitoring and TherapyNon-Invasive Vital Sign MonitoringHealthcare Technology and Patient Monitoring

Non-Invasive Wearable Patch Utilizing Seismocardiography for Peri-Operative Use in Surgical Patients

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Semiz, Beren, Carek, Andrew M., Johnson, Jessica C., Ahmad, Shireen, Heller, J. Alex, Vicente, Florencia G., Caron, Stacey, Hogue, Charles W. +2 more·2021·IEEE Journal of Biomedical and Health Informatics

Abstract

OBJECTIVE: Optimizing peri-operative fluid management has been shown to improve patient outcomes and the use of stroke volume (SV) measurement has become an accepted tool to guide fluid therapy. The Transesophageal Doppler (TED) is a validated, minimally invasive device that allows clinical assessment of SV. Unfortunately, the use of the TED is restricted to the intra-operative setting in anesthetized patients and requires constant supervision and periodic adjustment for accurate signal quality. However, post-operative fluid management is also vital for improved outcomes. Currently, there is no device regularly used in clinics that can track patient's SV continuously and non-invasively both during and after surgery. METHODS: In this paper, we propose the use of a wearable patch mounted on the mid-sternum, which captures the seismocardiogram (SCG) and electrocardiogram (ECG) signals continuously to predict SV in patients undergoing major surgery. In a study of 12 patients, hemodynamic data was recorded simultaneously using the TED and wearable patch. Signal processing and regression techniques were used to derive SV from the signals (SCG and ECG) captured by the wearable patch and compare it to values obtained by the TED. RESULTS: The results showed that the combination of SCG and ECG contains substantial information regarding SV, resulting in a correlation and median absolute error between the predicted and reference SV values of 0.81 and 7.56 mL, respectively. SIGNIFICANCE: This work shows promise for the proposed wearable-based methodology to be used as an alternative to TED for continuous patient monitoring and guiding peri-operative fluid management.

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  • The e-tattoo achieves one of the lowest current draws (940 μA) among wearable cardiac sensors developed in prior work.

    “This form factor coupled with innovative firmware for sensor interfacing and transmission of data allows us to achieve one of the lowest total device weights (2.5 g including battery) and current draws (940 µ A) among wearable cardiac sensors developed in prior work as illustrated via Ashby plot in Figure 1e. [18-24]”
  • The e-tattoo achieves one of the lowest total device weights (2.5 g including battery) among wearable cardiac sensors developed in prior work.

    “This form factor coupled with innovative firmware for sensor interfacing and transmission of data allows us to achieve one of the lowest total device weights (2.5 g including battery) and current draws (940 µ A) among wearable cardiac sensors developed in prior work as illustrated via Ashby plot in Figure 1e. [18-24]”

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Research works printed but not linked: 3

  1. [9]Chamberlain BM and Willshire RJ, “ Oesophageal doppler monitor (odm) guided individualised goal directed fluid management (igdfm) in surgery-a technical review,” surgery, vol. 19, p. 21, 2010.
  2. [10]Singer M, “ Continuous haemodynamic monitoring by oesophageal doppler (md thesis),” London: University of London, 1990.
  3. [45]Rodrigues JM, Cardoso PJ, Monteiro J, Lam R, Krzhizhanovskaya VV, Lees MH, Dongarra JJ, and Sloot PM, Computational Science–ICCS 2019: 19th International Conference, Faro, Portugal, June 12–14, 2019, Proceedings. Springer, 2019, vol. 11536. PMC7505107 32983283

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Authors
Semiz, B., Carek, A. M., Johnson, J. C., Ahmad, S., Heller, J. A., Vicente, F. G., Caron, S., Hogue, C. W., Etemadi, M., & Inan, O. T.
Affiliations
  • Georgia Institute of Technology (US)
  • Northwestern University (US)
Venue
IEEE Journal of Biomedical and Health Informatics
Published
2021-05
Volume
25
Issue
5
Pages
1572-1582
ISSN
  • 2168-2194 (ISSN-L)
  • 2168-2208
OpenAlex
W3094395646
Cited by
35
References
51
Citations by year
2026: 3 · 2025: 8 · 2024: 4 · 2023: 9 · 2022: 9 · 2021: 2
FWCI
4.57
Type
journal article
Language
en
Open access
Locations
  • IEEE Journal of Biomedical and Health Informatics (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institutes of Health (1R01HL130619-A1)
Topics
  • Health Sciences › Medicine › Surgery › Hemodynamic Monitoring and Therapy
  • Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
  • Health Sciences › Medicine › Surgery › Healthcare Technology and Patient Monitoring
Keywords
seismocardiography, wearable patch, stroke volume estimation, esophageal Doppler, electrocardiogram, continuous hemodynamic monitoring, major surgery, non-invasive monitoring
MeSH terms
Wearable Electronic Devices, Electrocardiography, Humans, Monitoring, Physiologic, Signal Processing, Computer-Assisted, Stroke Volume, Perioperative Care

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