A Vestibular Prosthesis With Highly-Isolated Parallel Multichannel Stimulation
Open accessAbstract
This paper presents an implantable vestibular stimulation system capable of providing high flexibility independent parallel stimulation to the semicircular canals in the inner ear for restoring three-dimensional sensation of head movements. To minimize channel interaction during parallel stimulation, the system is implemented with a power isolation method for crosstalk reduction. Experimental results demonstrate that, with this method, electrodes for different stimulation channels located in close proximity ( mm) can deliver current pulses simultaneously with minimum inter-channel crosstalk. The design features a memory-based scheme that manages stimulation to the three canals in parallel. A vestibular evoked potential (VEP) recording unit is included for closed-loop adaptive stimulation control. The main components of the prototype vestibular prosthesis are three ASICs, all implemented in a 0.6- μm high-voltage CMOS technology. The measured performance was verified using vestibular electrodes in vitro.
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Proximity of interface sites on tissue can result in crosstalk between channels due to current spread, which can compromise efficacy of the neural interface solution, requiring electrical or physical isolation between interface channels.
“However, the proximity of interface sites on the tissue can result in crosstalk between channels due to current spread. This can compromise the efficacy of the neural interface solution [77], requiring electrical [78] or physical isolation between the interface channel [71].”
From Active Neural Interface Circuits and Systems for Selective Control of Peripheral Nerves: A Review (2024) · cites this paper as [77]
A power isolation method was introduced, enabling parallel, multichannel stimulation with minimum crosstalk.
“To address this issue, a power isolation method was introduced, enabling parallel, multichannel stimulation with minimum crosstalk [77].”
From Active Neural Interface Circuits and Systems for Selective Control of Peripheral Nerves: A Review (2024) · cites this paper as [77]
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Cites
Better speech recognition with cochlear implants
Wilson, B. S., Finley, C. C., Lawson, D. T., Wolford, R. D., Eddington, D. K., & Rabinowitz, W. M. (1991) · Nature · doi:10.1038/352236a0 · Cited by 1,193 · see citing works
Cochlear Implants: System Design, Integration, and Evaluation
Zeng, F.-G., Rebscher, S., Harrison, W., Sun, X., & Feng, H. (2008) · IEEE Reviews in Biomedical Engineering · doi:10.1109/rbme.2008.2008250 · Cited by 878 · see citing works
Assessment: Vestibular testing techniques in adults and children [RETIRED]
Fife, T. D., Tusa, R. J., Furman, J. M. R., Zee, D. S., Frohman, E. M., Baloh, R. W., Hain, T. C., Goebel, J. A., Demer, J. L., & Eviatar, L. (2000) · Neurology · doi:10.1212/wnl.55.10.1431 · Cited by 262 · see citing works
Neural Variability, Detection Thresholds, and Information Transmission in the Vestibular System
Sadeghi, S. G., Chacron, M. J., Taylor, M. C., & Cullen, K. E. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.4690-06.2007 · Cited by 249 · see citing works
Santina, C. C. D., Migliaccio, A. A., & Patel, A. H. (2007) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2007.894629 · Cited by 173 · see citing works
Brandt, T., & Strupp, M. L. (2004) · Clinical Neurophysiology · doi:10.1016/j.clinph.2004.08.009 · Cited by 161 · see citing works
Prototype Neural Semicircular Canal Prosthesis using Patterned Electrical Stimulation
Gong, W., & Merfeld, D. M. (2000) · Annals of Biomedical Engineering · doi:10.1114/1.293 · Cited by 141 · see citing works
An Improved Method of Reducing Stimulus Artifact in the Electrically Evoked Whole-Nerve Potential
Miller, C. A., Abbas, P. J., & Brown, C. (2000) · Ear and Hearing · doi:10.1097/00003446-200008000-00003 · Cited by 122 · see citing works
System design and performance of a unilateral horizontal semicircular canal prosthesis
Gong, W., & Merfeld, D. M. (2002) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.979358 · Cited by 114 · see citing works
Chronic Vestibulo-Ocular Reflexes Evoked by a Vestibular Prosthesis
Merfeld, D. M., Haburcakova, C., Gong, W., & Lewis, R. F. (2007) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2007.891943 · Cited by 97 · see citing works
Adaptation to Steady-State Electrical Stimulation of the Vestibular System in Humans
Guyot, J., Sigrist, A., Pelizzone, M., et al. (2011) · Annals of Otology Rhinology & Laryngology · doi:10.1177/000348941112000301 · Cited by 96 · see citing works
Acclimation to Chronic Constant-Rate Peripheral Stimulation Provided by a Vestibular Prosthesis
Merfeld, D. M., Gong, W., Morrissey, J. H., Saginaw, M. A., Haburcakova, C., & Lewis, R. F. (2006) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2006.883645 · Cited by 93 · see citing works
Davidovics, N. S., Fridman, G. Y., Chiang, B., & Santina, C. C. D. (2010) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2010.2065241 · Cited by 90 · see citing works
Retinal Neurostimulator for a Multifocal Vision Prosthesis
Wong, Y. T., Dommel, N., Preston, P., Hallum, L. E., Lehmann, T., Lovell, N. H., & Suaning, G. J. (2007) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2007.903958 · Cited by 79 · see citing works
Fridman, G. Y., Davidovics, N. S., Dai, C., Migliaccio, A. A., & Santina, C. C. D. (2010) · Journal of the Association for Research in Otolaryngology · doi:10.1007/s10162-010-0208-5 · Cited by 77 · see citing works
Eye Movements in Response to Electrical Stimulation of the Lateral and Superior Ampullary Nerves
Guyot, J., Sigrist, A., Pelizzone, M., et al. (2011) · Annals of Otology Rhinology & Laryngology · doi:10.1177/000348941112000202 · Cited by 76 · see citing works
A Partial-Current-Steering Biphasic Stimulation Driver for Vestibular Prostheses
Constandinou, T. G., Georgiou, J., & Toumazou, C. (2008) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2008.927238 · Cited by 76 · see citing works
Chiang, B., Fridman, G. Y., Dai, C., Rahman, M. A., & Santina, C. C. D. (2011) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2011.2164937 · Cited by 65 · see citing works
An Electronic Prosthesis Mimicking the Dynamic Vestibular Function
Shkel, A. M., & Zeng, F. (2006) · Audiology and Neurotology · doi:10.1159/000090684 · Cited by 58 · see citing works
A Stimulator ASIC Featuring Versatile Management for Vestibular Prostheses
Jiang, D., Demosthenous, A., Perkins, T. A., Liu, X., & Donaldson, N. (2011) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2011.2138139 · Cited by 54 · see citing works
Self-citationDavidovics, N. S., Fridman, G. Y., & Santina, C. C. D. (2012) · Experimental Brain Research · doi:10.1007/s00221-012-3025-8 · Cited by 48 · see citing works
Davidovics, N. S., Rahman, M. A., Dai, C., Ahn, J., Fridman, G. Y., & Santina, C. C. D. (2013) · Journal of the Association for Research in Otolaryngology · doi:10.1007/s10162-013-0370-7 · Cited by 45 · see citing works
Gong, W., Haburcakova, C., & Merfeld, D. M. (2008) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2008.2001294 · Cited by 42 · see citing works
Hayden, R., Sawyer, S. A., Frey, E. C., et al. (2011) · Experimental Brain Research · doi:10.1007/s00221-011-2599-x · Cited by 38 · see citing works
Nie, K., Ling, L., Bierer, S. M., et al. (2013) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2013.2241433 · Cited by 33 · see citing works
Valentin, N. S., Hageman, K. N., Dai, C., et al. (2013) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2013.2259261 · Cited by 32 · see citing works
Demosthenous, A., Pachnis, I., Jiang, D., & Donaldson, N. (2013) · IEEE Sensors Journal · doi:10.1109/jsen.2013.2271477 · Cited by 30 · see citing works
Self-citationA fast passive phase shift keying modulator for inductively coupled implanted medical devices
Cirmirakis, D., Jiang, D., Demosthenous, A., et al. (2012) · doi:10.1109/esscirc.2012.6341314 · Cited by 17 · see citing works
Self-citationPhillips, J. O., Shepherd, S. J., Nowack, A. L., et al. (2012) · doi:10.1109/embc.2012.6347392 · Cited by 16 · see citing works
A Field-Programmable Analog Array Development Platform for Vestibular Prosthesis Signal Processing
Töreyin, H., & Bhatti, P. T. (2012) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2012.2216525 · Cited by 10 · see citing works
Alignment of angular velocity sensors for a vestibular prosthesis
DiGiovanna, J., Carpaneto, J., Micera, S., et al. (2012) · Journal of NeuroEngineering and Rehabilitation · doi:10.1186/1743-0003-9-14 · Cited by 10 · see citing works
Design of microelectrodes for a vestibular prosthesis
Hoffmann, K.-P., Poppendieck, W., Dörge, T., et al. (2010) · Publikationsdatenbank der Fraunhofer-Gesellschaft (Fraunhofer-Gesellschaft) · Cited by 8 · see citing works
A closed-loop neural prosthesis for vestibular disorders
Micera, S., DiGiovanna, J., Berthoz, A., et al. (2010) · Symposium on Neural Network Applications in Electrical Engineering · doi:10.1109/neurel.2010.5644048 · Cited by 6 · see citing works
An implantable 3-D vestibular stimulator with neural recording
Jiang, D., Demosthenous, A., Perkins, T. A., et al. (2012) · doi:10.1109/esscirc.2012.6341339 · Cited by 5 · see citing works
Self-citation3D hybrid electrode structure as implantable interface for a vestibular neural prosthesis in humans
Hoffmann, K. P., Poppendieck, W., Tätzner, S., et al. (2011) · doi:10.1109/iembs.2011.6090250 · Cited by 4 · see citing works
Kögler, V., Nguyen, T. A. K., DiGiovanna, J., et al. (2011) · International IEEE/EMBS Conference on Neural Engineering · doi:10.1109/ner.2011.5910537 · Cited by 4 · see citing works
Novel Telemetry System for Closed Loop Vestibular Prosthesis
Cirmirakis, D. (2013) · Doctoral thesis, UCL (University College London). · Cited by 3 · see citing works
Self-citationFinding physiological responses in vestibular evoked potentials
Nguyen, T. A. K., Kögler, V., DiGiovanna, J., et al. (2011) · doi:10.1109/iembs.2011.6090568 · Cited by 3 · see citing works
Hayden, R., Sawyer, S. A., Frey, E. C., et al. (2011) · Experimental Brain Research · doi:10.1007/s00221-011-2640-0 · Cited by 1 · see citing works
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Research works printed but not linked: 1
- T. A. Perkins, N. Donaldson, A. Demosthenous, and D. Jiang, "A switched capacitor crosstalk reduction method for vestibular nerve stimulators," in Proc. Int. Workshop Functional Electrical Stimulation, Vienna, Austria, Sep. 8-12, 2010, pp. 74-76.
Cited by
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A Multichannel High-Frequency Power-Isolated Neural Stimulator With Crosstalk Reduction
Jiang, D., & Demosthenous, A. (2018) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2018.2832541 · Cited by 36 · see citing works
Self-citationActive Neural Interface Circuits and Systems for Selective Control of Peripheral Nerves: A Review
Habibollahi, M., Jiang, D., Lancashire, H. T., & Demosthenous, A. (2024) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2024.3430038 · Cited by 11 · see citing works
“This can compromise the efficacy of the neural interface solution [77], requiring electrical [78] or physical isolation between the interface channel [71].”
Self-citation
- Authors
- Jiang, D., Cirmirakis, D., & Demosthenous, A.
- Affiliations
- University College London (GB)
- Venue
- IEEE Transactions on Biomedical Circuits and Systems
- Published
- 2015-02
- Volume
- 9
- Issue
- 1
- Pages
- 124-137
- ISSN
- 1932-4545 (ISSN-L)
- 1940-9990
- OpenAlex
- W1973835345
- Cited by
- 20
- References
- 39
- Citations by year
- 2025: 1 · 2024: 2 · 2023: 2 · 2022: 2 · 2021: 3 · 2018: 1 · 2017: 1 · 2016: 5 · 2015: 2 · 2014: 1
- FWCI
- 1.37
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- IEEE Transactions on Biomedical Circuits and Systems (publishedVersion, cc-by)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Funders
- European Commission (FP7-ICT-225929)
- CLONS project
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Physical Sciences › Engineering › Biomedical Engineering › Analog and Mixed-Signal Circuit Design
- Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
- Keywords
- vestibular prosthesis, semicircular canals, crosstalk reduction, power isolation, channel interaction, ASIC
- MeSH terms
- Electrodes, Implanted, Electric Stimulation Therapy, Humans, Prosthesis Design, Semicircular Canals, Vestibular Evoked Myogenic Potentials
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