Physiology and Mathematics of Myoelectric Signals
Abstract
The myoelectric (ME) signal is the electrical manifestation of the neuromuscular activation associated with a contracting muscle. It is an exceedingly complicated signal which is affected by the anatomical and physiological properties of muscles, the control scheme of the peripheral nervous system, as well as the characteristics of the instrumentation that is used to detect and observe it. Most of the relationships between the ME signal and the properties of a contracting muscle which are presently employed have evolved serendipitously. The lack of a proper description of the ME signal is probably the greatest single factor which has hampered the development of electromyography (EMG) into a precise discipline.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Muscle force is partly proportional to the amplitude of the EMG signal.
“The fact that the force developed by a muscle is partly proportional to the amplitude of the EMG signal [25] is the physiological rationale for the interpretation of these ratios.”
From Comparison of muscle activation imbalance following core stability or general exercises in nonspecific low back pain: a quasi-randomized controlled trial (2020) · cites this paper as [25]
Cites
FUNCTIONAL SIGNIFICANCE OF CELL SIZE IN SPINAL MOTONEURONS
Henneman, E., Somjen, G., & Carpenter, D. O. (1965) · Journal of Neurophysiology · doi:10.1152/jn.1965.28.3.560 · Cited by 2,294 · see citing works
New Developments in Electromyography and Clinical Neurophysiology.
(1974) · Archives of Neurology · doi:10.1001/archneur.1974.00490320078016 · Cited by 1,623 · see citing works
The discharge of impulses in motor nerve fibres
Adrian, E. D., & Bronk, D. W. (1929) · The Journal of Physiology · doi:10.1113/jphysiol.1929.sp002557 · Cited by 796 · see citing works
Edström, L., & Kugelberg, E. (1968) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.31.5.424 · Cited by 668 · see citing works
The relation between the surface electromyogram and muscular force.
Milner‐Brown, H. S., & Stein, R. B. (1975) · The Journal of Physiology · doi:10.1113/jphysiol.1975.sp010904 · Cited by 644 · see citing works
Lindström, L., Magnusson, R., & Petersén, I. (1972) · PubMed · Cited by 554 · see citing works
Changes in firing rate of human motor units during linearly changing voluntary contractions
Milner‐Brown, H. S., Stein, R. B., & Yemm, R. (1973) · The Journal of Physiology · doi:10.1113/jphysiol.1973.sp010193 · Cited by 553 · see citing works
A new bipolar electrode for electromyography
Basmajian, J. V., & STECKO, G. (1962) · Journal of Applied Physiology · doi:10.1152/jappl.1962.17.5.849 · Cited by 533 · see citing works
The contractile properties of human motor units during voluntary isometric contractions
Milner‐Brown, H. S., Stein, R. B., & Yemm, R. (1973) · The Journal of Physiology · doi:10.1113/jphysiol.1973.sp010087 · Cited by 477 · see citing works
Synchronization of human motor units: Possible roles of exercise and supraspinal reflexes
Milner‐Brown, H. S., & Lee, R. G. (1975) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(75)90245-x · Cited by 431 · see citing works
Person, R. S., & Kudina, L. P. (1972) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(72)90058-2 · Cited by 413 · see citing works
The margin of safety of neuromuscular transmission
Paton, W. D. M., & Waud, D. R. (1967) · The Journal of Physiology · doi:10.1113/jphysiol.1967.sp008237 · Cited by 413 · see citing works
The effect of activation history on tension production by individual muscle units
Burke, R. E., Rudomin, P., & Zajac, F. E. (1976) · Brain Research · doi:10.1016/0006-8993(76)90031-7 · Cited by 406 · see citing works
The relation between force and integrated electrical activity in fatigued muscle
Edwards, R. G., & Lippold, O. C. J. (1956) · The Journal of Physiology · doi:10.1113/jphysiol.1956.sp005558 · Cited by 324 · see citing works
Anatomy and innervation ratios in motor units of cat gastrocnemius
Burke, R. E., & Tsairis, P. (1973) · The Journal of Physiology · doi:10.1113/jphysiol.1973.sp010370 · Cited by 308 · see citing works
Electrodes and the measurement of bioelectric events
Shipton, H. W. (1973) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(73)90185-5 · Cited by 303 · see citing works
Grimby, L., & Hannerz, J. (1977) · The Journal of Physiology · doi:10.1113/jphysiol.1977.sp011699 · Cited by 303 · see citing works
Failure of neuromuscular propagation in rats
Krnjević, K., & Miledi, R. (1958) · The Journal of Physiology · doi:10.1113/jphysiol.1958.sp005944 · Cited by 280 · see citing works
Electrodes and the measurement of bioelectric events
Geddes, L. A. (1972) · Medical Entomology and Zoology · Cited by 276 · see citing works
Activity of single motor units from human forearm muscles during voluntary isometric contractions
Freund, H. J., von Büdingen, H. J., & Dietz, V. H. (1975) · Journal of Neurophysiology · doi:10.1152/jn.1975.38.4.933 · Cited by 263 · see citing works
Action Potential Parameters in Normal Human Muscle and their Dependence on Physical Variables.
Buchthal, F., Guld, C., & Rosenfalck, P. (1954) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1954.tb01167.x · Cited by 260 · see citing works
Hughes, J. R. (1958) · Physiological Reviews · doi:10.1152/physrev.1958.38.1.91 · Cited by 242 · see citing works
Statistical Analysis of Motor Unit Firing Patterns in a Human Skeletal Muscle
Clamann, H. P. (1969) · Biophysical Journal · doi:10.1016/s0006-3495(69)86448-9 · Cited by 241 · see citing works
Action Potential Paraneters in Normal Human Musele and their Physiological Determinants
BUCHTHAL, F., PINELLI, P., & Rosenfalck, P. (1954) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1954.tb01168.x · Cited by 230 · see citing works
Goldberg, L. J., & Derfler, B. (1977) · Journal of Neurophysiology · doi:10.1152/jn.1977.40.4.879 · Cited by 185 · see citing works
Knowlton, G. C., BENNETT, R. L., & McClure, R. (1951) · PubMed · Cited by 181 · see citing works
The rhythmical activity of groups of motor units in the voluntary contraction of muscle
Lippold, O. C. J., Redfearn, J. W. T., & Vučo, J. (1957) · The Journal of Physiology · doi:10.1113/jphysiol.1957.sp005828 · Cited by 170 · see citing works
Activity of single motor units during isometric tension
Clamann, H. P. (1970) · Neurology · doi:10.1212/wnl.20.3.254 · Cited by 170 · see citing works
Rhythmic activity of a group of human motoneurones during voluntary contraction of a muscle
Person, R. S. (1974) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(74)90225-9 · Cited by 165 · see citing works
THE ELECTROMYOGRAPHY OF FATIGUE
LIPPOLD, O. C. J., REDFEARN, J. W. T., & Vučo, J. (1960) · Ergonomics · doi:10.1080/00140136008930474 · Cited by 162 · see citing works
Signal Characteristics of EMG at Different Levels of Muscle Tension
Komi, P. V., & Viitasalo, J. H. T. (1976) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1976.tb10195.x · Cited by 159 · see citing works
Single fibre electromyography in various processes affecting the anterior horn cell
Stålberg, E., Schwartz, M. S., & Trontelj, J. V. (1975) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(75)90166-5 · Cited by 158 · see citing works
Motor Unit Territory in Different Human Muscles
Buchthal, F., Erminio, F., & Rosenfalck, P. (1959) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1959.tb01678.x · Cited by 157 · see citing works
Tanji, J., & Κato, M. (1973) · Experimental Neurology · doi:10.1016/0014-4886(73)90111-8 · Cited by 156 · see citing works
Some features of different motor units in human biceps brachii
Gydikov, A., & Kosarov, D. (1974) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/bf00587056 · Cited by 153 · see citing works
Facility of motor unit control during tasks defined directly in terms of unit behaviors
Thomas, J., Schmidt, E. M., & Hambrecht, F. T. (1978) · Experimental Neurology · doi:10.1016/0014-4886(78)90230-3 · Cited by 137 · see citing works
Discharge Properties of Motor Units in Relation to Recruitment Order in Voluntary Contraction
Hannerz, J. (1974) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1974.tb05692.x · Cited by 131 · see citing works
Synchronous activity in normal and atrophic muscle
Buchthal, F., & Madsen, A. (1950) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(50)90079-4 · Cited by 126 · see citing works
Luca, C. J. D., & Forrest, W. J. (1973) · Kybernetik · doi:10.1007/bf00289169 · Cited by 122 · see citing works
Effect of motor-unit firing time statistics on e.m.g. spectra
Lago, P. J. A., & Jones, N. B. (1977) · Medical & Biological Engineering & Computing · doi:10.1007/bf02457923 · Cited by 121 · see citing works
Buchthal, F., Guld, C., & Rosenfalck, P. (1957) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1957.tb01396.x · Cited by 114 · see citing works
Dietz, V., Bischofberger, E., Wita, C. W., & Freund, H. (1976) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(76)90183-8 · Cited by 113 · see citing works
The Mechanisms of Post-Tetanic Potentiation in Cat Soleus and Gastrocnemius Muscles
Standaert, F. G. (1964) · The Journal of General Physiology · doi:10.1085/jgp.47.5.987 · Cited by 108 · see citing works
Mori, S. (1973) · Journal of Neurophysiology · doi:10.1152/jn.1973.36.3.458 · Cited by 82 · see citing works
Stålberg, E., Schwartz, M. S., Thiele, B., et al. (1976) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(76)90002-2 · Cited by 67 · see citing works
Borg, J., Grimby, L., & Hannerz, J. (1978) · The Journal of Physiology · doi:10.1113/jphysiol.1978.sp012266 · Cited by 67 · see citing works
William, R., Luschei, E. S., & Hoffman, D. S. (1978) · Experimental Neurology · doi:10.1016/0014-4886(78)90179-6 · Cited by 54 · see citing works
An Electrode for Recording Single Motor Unit Activity During Strong Muscle Contractions
Luca, C. J. D., & Forrest, W. J. (1972) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.1972.324140 · Cited by 52 · see citing works
Effect of prior activity on properties of different types of motor units.
Olson, C. B., & Swett, C. P. (1971) · Journal of Neurophysiology · doi:10.1152/jn.1971.34.1.1 · Cited by 52 · see citing works
ACTIVITIES OF SINGLE MOTOR UNITS IN MAN DURING SLIGHT VOLUNTARY EFFORTS
Gilson, A. S., & Mills, W. B. (1941) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1941.133.3.658 · Cited by 52 · see citing works
Stulen, F. B., & Luca, C. J. D. (1978) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(78)90137-2 · Cited by 51 · see citing works
Human alpha motoneurone discharge, a statistical analysis
Kranz, H., & Baumgartner, G. (1974) · Brain Research · doi:10.1016/0006-8993(74)90282-0 · Cited by 49 · see citing works
A model for myoelectric signal generation
Brody, G., Scott, R. N., & Balasubramanian, R. (1974) · Medical & Biological Engineering & Computing · doi:10.1007/bf02629832 · Cited by 48 · see citing works
Luca, C. J. D., & van Dyk, E. J. (1975) · Biophysical Journal · doi:10.1016/s0006-3495(75)85893-0 · Cited by 46 · see citing works
Increased voltage of the muscle action potential of normal subjects after local cooling
Ricker, K., Hertel, G., & Stodieck, G. (1977) · Journal of Neurology · doi:10.1007/bf00312813 · Cited by 41 · see citing works
Landau, W. M. (1969) · Neurology · doi:10.1212/wnl.19.8.812-b · Cited by 40 · see citing works
Analysis of multiunit spike records.
Bíró, G., & Partridge, L. (1971) · Journal of Applied Physiology · doi:10.1152/jappl.1971.30.4.521 · Cited by 39 · see citing works
A stochastic model of skeletal muscle based on motor unit properties
Coggshall, J. C., & Bekey, G. A. (1970) · Mathematical Biosciences · doi:10.1016/0025-5564(70)90136-7 · Cited by 34 · see citing works
A model for a motor unit train recorded during constant force isometric contractions
Luca, C. J. D. (1975) · Biological Cybernetics · doi:10.1007/bf00337255 · Cited by 32 · see citing works
Stochastic properties of motoneuron activity and the effect of muscular length
Shiavi, R., & Negin, M. (1975) · Biological Cybernetics · doi:10.1007/bf02281973 · Cited by 27 · see citing works
Brandstater, M. E., & Lambert, E. H. (2015) · KARGER eBooks · doi:10.1159/000394021 · Cited by 27 · see citing works
Model of the electromyographic activity during brief isometric contractions
Meijers, L. M. M., Teulings, J. L. H. M., & Eijkman, E. G. J. (1976) · Biological Cybernetics · doi:10.1007/bf00337044 · Cited by 24 · see citing works
Stochastic properties of individual motor unit interspike intervals
Masland, W. S., Sheldon, D. D., & Hershey, C. (1969) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1969.217.5.1384 · Cited by 19 · see citing works
Analysis of point process signals applied to motor unit firing patterns
Gath, I. (1974) · Mathematical Biosciences · doi:10.1016/0025-5564(74)90092-3 · Cited by 15 · see citing works
[Work of human motor units during rhythmic movements].
Vs, G., Td, S., Ml, M., et al. (1971) · PubMed · Cited by 14 · see citing works
Duration of motor unit potentials from fine-wire electrodes.
Basmajian, J. V., & Cross, G. L. (1971) · PubMed · Cited by 12 · see citing works
Ah, L., & Tuomola, H. (1975) · PubMed · Cited by 11 · see citing works
[Statistical parameters of the electrical signal of a muscle model].
Vm, B. (1970) · PubMed · Cited by 11 · see citing works
[QUANTITATIVE CHARACTERISTICS OF WORK OF MOTOR UNITS UNDER STATIONARY CONDITIONS].
Vs, G., IVANOVA, A. N., KOTS, I. M., et al. (1964) · PubMed · Cited by 10 · see citing works
Effect of Direct Tetanization on Twitch Tension in Developing Cat Leg Muscles
Nyström, B. (1968) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1968.tb04239.x · Cited by 9 · see citing works
Modelling of interference bioelectric activity
Libkind (1968) · Биофизика · Cited by 7 · see citing works
Synchronization of motor units and its simulation in parallel feedback system
Mori, S., & Ishida, A. (1976) · Biological Cybernetics · doi:10.1007/bf01259393 · Cited by 6 · see citing works
Miyazaki, S. (1977) · Computers and Biomedical Research · doi:10.1016/0010-4809(77)90043-x · Cited by 6 · see citing works
Pattern of human motoneuron activity during voluntary muscular contraction
Person, R. S., & Kudina, L. P. (1972) · Neurophysiology · doi:10.1007/bf01063758 · Cited by 6 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
A new strategy for multifunction myoelectric control
Hudgins, B., Parker, P., & Scott, R. N. (1993) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.204774 · Cited by 2,149 · see citing works
Behaviour of human motor units in different muscles during linearly varying contractions
de Luca, C. J., LeFever, R. S., McCue, M. P., & Xenakis, A. P. (1982) · The Journal of Physiology · doi:10.1113/jphysiol.1982.sp014293 · Cited by 719 · see citing works
Self-citationObjective motor response onset detection in surface myoelectric signals
Staude, G., & Wolf, W. (1999) · Medical Engineering & Physics · doi:10.1016/s1350-4533(99)00067-3 · Cited by 217 · see citing works
Acoustic myography: A noninvasive monitor of motor unit fatigue
Barry, D. T., Geiringer, S. R., & Ball, R. D. (1985) · Muscle & Nerve · doi:10.1002/mus.880080303 · Cited by 208 · see citing works
Activation imbalances in lumbar spine muscles in the presence of chronic low back pain
Oddsson, L. I. E., & De Luca, C. J. (2003) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01183.2001 · Cited by 147 · see citing works
Self-citationRectification of SEMG as a tool to demonstrate synchronous motor unit activity during vibration
Sebik, O., Karacan, I., Cidem, M., & Türker, K. S. (2013) · Journal of Electromyography and Kinesiology · doi:10.1016/j.jelekin.2012.09.009 · Cited by 44 · see citing works
Shamsi, M., Mirzaei, M., & HamediRad, M. (2020) · BMC Sports Science, Medicine and Rehabilitation · doi:10.1186/s13102-020-00173-0 · Cited by 30 · see citing works
- Authors
- De Luca, C. J.
- Venue
- IEEE Transactions on Biomedical Engineering
- Published
- 1979-06
- Volume
- BME-26
- Issue
- 6
- Pages
- 313-325
- ISSN
- 0018-9294 (ISSN-L)
- OpenAlex
- W2118395035
- Cited by
- 684
- References
- 74
- Citations by year
- 2026: 7 · 2025: 4 · 2024: 16 · 2023: 21 · 2022: 14 · 2021: 18 · 2020: 23 · 2019: 22 · 2018: 19 · 2017: 10 · 2016: 35 · 2015: 30 · 2014: 20 · 2013: 15 · 2012: 20
- FWCI
- 12.78
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- IEEE Transactions on Biomedical Engineering (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Muscle activation and electromyography studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Keywords
- myoelectric signals, electromyography, neuromuscular activation, muscle contraction, muscle physiology
- MeSH terms
- Action Potentials, Electromyography, Electrophysiology, Humans, Mathematics, Models, Neurological, Motor Neurons, Muscle Contraction, Muscles, Recruitment, Neurophysiological
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review