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Biopsy using a Magnetic Capsule Endoscope Carrying, Releasing, and Retrieving Untethered Microgrippers
Open accessAbstract
This paper proposes a new wireless biopsy method where a magnetically actuated untethered soft capsule endoscope carries and releases a large number of thermo-sensitive, untethered microgrippers (μ-grippers) at a desired location inside the stomach and retrieves them after they self-fold and grab tissue samples. We describe the working principles and analytical models for the μ-gripper release and retrieval mechanisms, and evaluate the proposed biopsy method in ex vivo experiments. This hierarchical approach combining the advanced navigation skills of centimeter-scaled untethered magnetic capsule endoscopes with highly parallel, autonomous, submillimeter scale tissue sampling μ-grippers offers a multifunctional strategy for gastrointestinal capsule biopsy.
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Citations
Cites
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Lee, H., Lee, B. P., & Messersmith, P. B. (2007) · Nature · doi:10.1038/nature05968 · Cited by 2,043
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Sitti, M., Ceylan, H., Hu, W., Giltinan, J., Turan, M., Yim, S., & Diller, E. (2015) · Proceedings of the IEEE · doi:10.1109/jproc.2014.2385105 · Cited by 893
Self-citation3D printing of functional microrobots
Li, J., & Pumera, M. (2021) · Chemical Society Reviews · doi:10.1039/d0cs01062f · Cited by 303
Magnetic Living Hydrogels for Intestinal Localization, Retention, and Diagnosis
Liu, X., Yang, Y., Inda, M. E., Lin, S., Wu, J., Kim, Y., Chen, X., Ma, D., Lu, T. K., & Zhao, X. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202010918 · Cited by 175
Preliminary results of a handheld nerve electrode insertion device
Yim, S., Oh, Y.-E., Choi, W., Park, H., Jeong, J., Ihn, Y., Hwang, D., Oh, S.-R., Kim, J., & Kim, K. (2018) · 2018 IEEE International Conference on Robotics and Automation (ICRA) · doi:10.1109/icra.2018.8460882 · Cited by 4
Metadata
- Authors
- Yim, S., Gultepe, E., Gracias, D. H., & Sitti, M.
- Venue
- IEEE Transactions on Biomedical Engineering
- Published
- 2014-02
- Volume
- 61
- Issue
- 2
- Pages
- 513-521
- ISSN
- 0018-9294 (ISSN-L)
- 1558-2531
- OpenAlex
- W2007453190
- Cited by
- 292
- References
- 1
- FWCI
- 6.38
- Type
- journal article
- Language
- en
- Open access
- green
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- The paper
- Yim, S., Gultepe, E., Gracias, D. H., & Sitti, M. (2014). Biopsy using a Magnetic Capsule Endoscope Carrying, Releasing, and Retrieving Untethered Microgrippers. IEEE Transactions on Biomedical Engineering. https://doi.org/10.1109/tbme.2013.2283369
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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