Arterial blood pressure estimation from local pulse wave velocity using dual-element photoplethysmograph probe
Abstract
An arterial compliance, dual-element photoplethysmograph probe for local pulse wave velocity (PWV) measurement was developed. Initially, the experimental validation study was performed on 25 young volunteers (age =24.5 ± 4 years). Local PWV was assessed from a small section (23 mm) of the carotid artery. The prototype device demonstrated its capability of measuring reliable, repeatable, and reproducible carotid local PWV. Further, in 15 healthy male volunteers (age = 22.25 ± 3.5 years), carotid local PWV and brachial blood pressure (BP) were continuously recorded during their postexercise recovery period. Local PWV followed the changes in arterial BP parameters. The group average correlation coefficients (r) of local PWV versus BP parameters were between 0.772 ± 0.033 and 0.934 ± 0.028. In a population of 50 patients (normotensive and hypertensive) aged 24-80 years, local PWV-BP correlations were investigated. Local PWV tended to follow the diastolic BP (DBP; r = 0.82) and mean arterial pressure (r = 0.83) better than systolic BP (SBP; r = 0.69). It was significantly inferior in tracking pulse pressure values (r = 0.35). Cuffless estimation of arterial pressure was also performed on the same patients using measured carotid local PWV with best-case calibrations. Local PWV yielded good DBP prediction than SBP prediction. Statistically, significant correlation (r = 0.79) and a root-mean-square error of 5.26 mmHg versus reference brachial DBP were achieved. The introduced technique has a potential for short- or long-term noninvasive, cuffless monitoring of BP parameters from superficial arteries.
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PTT, used to determine PWV and estimate blood pressure without a cuff, requires extraction of the time delay from two PPG waveforms or from an ECG and PPG waveform.
“Additionally, some parameters in the literature such as pulse transit time (PTT), which is used to determine pulse wave velocity (PWV) and estimate blood pressure without a cuff, requires extraction of the time delay from two PPG waveforms or from an ECG and PPG waveform [31,32].”
From Sources of inaccuracy in photoplethysmography for continuous cardiovascular monitoring (2021) · cites this paper as [31]
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Sources of inaccuracy in photoplethysmography for continuous cardiovascular monitoring
Fine, J., Branan, K. L., Rodriguez, A. J., Boonya-ananta, T., Ajmal, Ramella-Roman, J. C., McShane, M. J., & Coté, G. L. (2021) · Biosensors · doi:10.3390/bios11040126 · Cited by 348 · see citing works
- Authors
- Nabeel, P. M., Karthik, S., Joseph, J., & Sivaprakasam, M.
- Affiliations
- Indian Institute of Technology Madras (IN)
- Venue
- IEEE Transactions on Instrumentation and Measurement
- Published
- 2018-06
- Volume
- 67
- Issue
- 6
- Pages
- 1399-1408
- ISSN
- 0018-9456 (ISSN-L)
- 1557-9662
- OpenAlex
- W2790723868
- Cited by
- 72
- References
- 30
- Citations by year
- 2026: 2 · 2025: 9 · 2024: 13 · 2023: 6 · 2022: 6 · 2021: 11 · 2020: 13 · 2019: 8 · 2018: 4
- FWCI
- 3.60
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- IEEE Transactions on Instrumentation and Measurement (publishedVersion)
- Funders
- Science and Engineering Research Board, Department of Science and Technology, Government of India
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Health Sciences › Medicine › Surgery › Hemodynamic Monitoring and Therapy
- Keywords
- arterial blood pressure estimation, carotid artery, cuffless blood pressure measurement, non-invasive blood pressure measurement, arterial compliance, post-exercise recovery, hypertension, pulse pressure
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