Clinical inertia causing new or progression of diabetic retinopathy in type 2 diabetes: A retrospective cohort study: 临床惰性可导致2型糖尿病患者新发视网膜病变或视网膜病变进展:一项回顾性队列研究
Abstract
Background Clinical inertia is a failure to intensify treatment according to evidence-based guidelines, and can have both short- and long-term adverse effects for type 2 diabetes (T2D). The aim of the present study was to demonstrate the effects of clinical inertia on glycemic control and diabetes-related complications. Methods A retrospective cohort study was conducted at a university-based hospital in Thailand. Medical records were evaluated retrospectively from January 2010 to December 2014. Patients were classified into two groups: clinical inertia and non-inertia. Clinical inertia was defined as failure to initiate insulin within 3 months in patients with HbA1c ≥9 % who were already taking two oral antidiabetic agents. Results From 1206 records, 98 patients with mean HbA1c of 10.3 % were identified and enrolled in the study. The median follow-up time of these patients was 29.5 months and 68.4 % were classified into the clinical inertia group. The mean (± SD) HbA1c decrement in the clinical inertia and non-inertia groups was 0.82 ± 1.50 % and 3.02 ± 1.80 %, respectively, at 6 months (P Conclusions Clinical inertia can cause persistently poor glycemic control and speed up the progression of DR in T2D.
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Clinical inertia results in poor glycemic control.
“Clinical inertia results in poor glycemic control and speeds up the progression to complications such as diabetic retinopathy and reduced life expectancy [11,29].”
From Clinical Inertia in the Management of Type 2 Diabetes Mellitus: A Systematic Review (2023) · cites this paper as [29]
Clinical inertia speeds up progression to complications such as diabetic retinopathy and reduced life expectancy.
“Clinical inertia results in poor glycemic control and speeds up the progression to complications such as diabetic retinopathy and reduced life expectancy [11,29].”
From Clinical Inertia in the Management of Type 2 Diabetes Mellitus: A Systematic Review (2023) · cites this paper as [29]
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- Authors
- Osataphan, S., Chalermchai, T., & Ngaosuwan, K.
- Affiliations
- Srinakharinwirot University (TH)
- Mae Fah Luang University (TH)
- Corresponding author
- Ngaosuwan, Kanchana
- Venue
- Journal of Diabetes
- Publisher
- Wiley
- Published
- 2016-07-12
- Volume
- 9
- Issue
- 3
- Pages
- 267-274
- ISSN
- 1753-0393 (ISSN-L)
- 1753-0407
- OpenAlex
- W2376943461
- Cited by
- 49
- References
- 17
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 5 · 2023: 6 · 2022: 5 · 2021: 6 · 2020: 6 · 2019: 5 · 2018: 8 · 2017: 2
- FWCI
- 5.03
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Diabetes (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Missouri Soybean Merchandising Council
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Ophthalmology › Retinal Diseases and Treatments
- Keywords
- clinical inertia, diabetic retinopathy, type 2 diabetes, glycemic control, HbA1c, insulin initiation, oral antidiabetic drugs, retinopathy progression, general practitioners, diabetes complications
- MeSH terms
- Adult, Aged, Aged, 80 and over, Diabetes Mellitus, Type 2, Diabetic Retinopathy, Female, Glycated Hemoglobin, Hospitals, University, Humans, Hypoglycemic Agents, Insulin, Male, Middle Aged, Retrospective Studies, Risk Factors, Thailand, Time Factors, Logistic Models, Disease Progression
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