Declining signal dependence of N rf2‐ M af S ‐regulated gene expression correlates with aging phenotypes

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Transcription Factor Nrf2 Coordinately Regulates a Group of Oxidative Stress-inducible Genes in Macrophages

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Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans

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Stress-activated cap’n’collar transcription factors in aging and human disease

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Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid

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Keap1/Nrf2 Signaling Regulates Oxidative Stress Tolerance and Lifespan in Drosophila

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Metformin Induces a Dietary Restriction-Like State and the Oxidative Stress Response to Extend C. elegans Healthspan via AMPK, LKB1 and SKN-1

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Collapse of proteostasis represents an early molecular event in <i>Caenorhabditis elegans</i> aging

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Two neurons mediate diet-restriction-induced longevity in C. elegans

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Genome-Wide Transcript Profiles in Aging and Calorically Restricted Drosophila melanogaster

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Nrf2 signaling: An adaptive response pathway for protection against environmental toxic insults

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The redox stress hypothesis of aging

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Making a better RNAi vector for Drosophila: use of intron spacers

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The cell cycle is a redox cycle: Linking phase-specific targets to cell fate

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Cellular stress response pathways and ageing: intricate molecular relationships

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A New Method for Detection and Quantification of Heartbeat Parameters in Drosophila, Zebrafish, and Embryonic Mouse Hearts

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Down-Regulated NF-E2–Related Factor 2 in Pulmonary Macrophages of Aged Smokers and Patients with Chronic Obstructive Pulmonary Disease

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A Versatile ΦC31 Based Reporter System for Measuring AP-1 and Nrf2 Signaling in Drosophila and in Tissue Culture

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Age-Associated Vascular Oxidative Stress, Nrf2 Dysfunction, and NF- B Activation in the Nonhuman Primate Macaca mulatta

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KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging

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The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation

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Nrf2 as a target for cancer chemoprevention

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Formation of a Monomeric DNA Binding Domain by Skn-1 bZIP and Homeodomain Elements

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Small Maf Proteins in Mammalian Gene Control: Mere Dimerization Partners or Dynamic Transcriptional Regulators?

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Age-related alterations in the activation of heat shock transcription factor 1 in rat hepatocytes

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Genetic activation of Nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in aDrosophilamodel of Parkinson’s disease

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Screening assays for heart function mutants in Drosophila

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Epigenetic Control of Aging

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The function of hypoxia‐inducible factor 1 (HIF‐1) is impaired in senescent mice

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Increased age reduces DAF-16 and SKN-1 signaling and the hormetic response of Caenorhabditis elegans to the xenobiotic juglone

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Age-associated oxidative damage to the p62 promoter: implications for Alzheimer disease

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Drosophila as a model to study cardiac aging

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Age-associated changes in SAPK/JNK and p38 MAPK signaling in response to the generation of ROS by 3-nitropropionic acid

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Proteostasis and REDOX state in the heart

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Cap ‘n’ collar B cooperates with a small Maf subunit to specify pharyngeal development and suppress Deformed homeotic function in the Drosophila head

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The Dorothy enhancer has tinman binding sites and drives hopscotch‐induced tumor formation

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Basic Leucine Zipper Protein Cnc-C Is a Substrate and Transcriptional Regulator of the Drosophila 26S Proteasome

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Genome wide analysis of common and specific stress responses in adult drosophila melanogaster

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The Biology of Proteostasis in Aging and Disease

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Redox metabolism: ROS as specific molecular regulators of cell signaling and function

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Nrf2 and Oxidative Stress: A General Overview of Mechanisms and Implications in Human Disease

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Oxidative stress response and Nrf2 signaling in aging

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SKN-1/Nrf, stress responses, and aging in Caenorhabditis elegans

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NRF2 and NF-қB interplay in cerebrovascular and neurodegenerative disorders: Molecular mechanisms and possible therapeutic approaches

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The Aging Epigenome

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A novel and compact review on the role of oxidative stress in female reproduction

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Natural product-derived pharmacological modulators of Nrf2/ARE pathway for chronic diseases

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Silver nanoparticles have lethal and sublethal adverse effects on development and longevity by inducing ROS-mediated stress responses

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NRF2 as a Therapeutic Target in Neurodegenerative Diseases

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Sulforaphane and Other Nutrigenomic Nrf2 Activators: Can the Clinician’s Expectation Be Matched by the Reality?

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Transcription factor NFE2L2/NRF2 modulates chaperone-mediated autophagy through the regulation of LAMP2A

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NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology

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NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer’s models

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Molecular Mechanisms and Genetics of Oxidative Stress in Alzheimer’s Disease

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Chronic oxidative stress promotes H2AX protein degradation and enhances chemosensitivity in breast cancer patients

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Are Astrocytes the Predominant Cell Type for Activation of Nrf2 in Aging and Neurodegeneration?

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Nrf2 dysfunction and impaired cellular resilience to oxidative stressors in the aged vasculature: from increased cellular senescence to the pathogenesis of age-related vascular diseases

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Mechanisms and functions of Nrf2 signaling in Drosophila

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Deficiency in the transcription factor NRF2 worsens inflammatory parameters in a mouse model with combined tauopathy and amyloidopathy

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Proteasome dysfunction inDrosophilasignals to an Nrf2-dependent regulatory circuit aiming to restore proteostasis and prevent premature aging

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Suppression of transcriptional drift extends C. elegans lifespan by postponing the onset of mortality

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The Recent Trend in the Use of Multistrain Probiotics in Livestock Production: An Overview

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Proteostasis and longevity: when does aging really begin?

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The transcription factor Maf-S regulates metabolic resistance to insecticides in the malaria vector Anopheles gambiae

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NRF2 signalling in cytoprotection and metabolism

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Pharmacological Strategies to Retard Cardiovascular Aging

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A correlation of reactive oxygen species accumulation by depletion of superoxide dismutases with age-dependent impairment in the nervous system and muscles of Drosophila adults

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A Review of Oxidative Stress Products and Related Genes in Early Alzheimer’s Disease

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Unique cistrome defined as CsMBE is strictly required for Nrf2-sMaf heterodimer function in cytoprotection

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The Role of Free Radicals in Autophagy Regulation: Implications for Ageing

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Nuclear Factor–Erythroid-2–Related Factor 2 in Aging and Lung Fibrosis

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6-bromo-indirubin-3′-oxime (6BIO), a Glycogen synthase kinase-3β inhibitor, activates cytoprotective cellular modules and suppresses cellular senescence-mediated biomolecular damage in human fibroblasts

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Targeting Transcription Factor Nrf2 (Nuclear Factor Erythroid 2-Related Factor 2) for the Intervention of Vascular Cognitive Impairment and Dementia

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Increases of iASPP-Keap1 interaction mediated by syringin enhance synaptic plasticity and rescue cognitive impairments via stabilizing Nrf2 in Alzheimer's models

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Biological resilience and aging: Activation of stress response pathways contributes to lifespan extension

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The redox-sensing gene Nrf2 affects intestinal homeostasis, insecticide resistance, and Zika virus susceptibility in the mosquito Aedes aegypti

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Preferential uptake of antioxidant carbon nanoparticles by T lymphocytes for immunomodulation

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Chronic PERK induction promotes Alzheimer-like neuropathology in Down syndrome: Insights for therapeutic intervention

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Cap-n-Collar Promotes Tissue Regeneration by Regulating ROS and JNK Signaling in the Drosophila melanogaster Wing Imaginal Disc

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Signal Transduction, Ageing and Disease

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Toward a Consensus in the Repertoire of Hemocytes Identified in Drosophila

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Potential Anti-Aging Substances Derived from Seaweeds

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The Evaluation of Geroprotective Effects of Selected Flavonoids in Drosophila melanogaster and Caenorhabditis elegans

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Contesting the dogma of an age-related heat shock response impairment: implications for cardiac-specific age-related disorders

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Basic mechanisms of longevity: A case study of Drosophila pro-longevity genes

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Tert-buthylhydroquinone pre-conditioning exerts dual effects in old female rats exposed to 3-nitropropionic acid

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Small Maf functions in the maintenance of germline stem cells in the Drosophila testis

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Acute hypoxia effects on Keap1/Nrf2 (Mafs)-GST pathway related oxidative metabolism in muscle of Japanese flounder (Paralichthys olivaceus)

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Silencing Bach1 alters aging-related changes in the expression of Nrf2-regulated genes in primary human bronchial epithelial cells

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A Drosophila ABC Transporter Regulates Lifespan

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Violent behaviour on construction sites: structural equation modelling of its impact on unsafe behaviour using partial least squares

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The Indirubin Derivative 6-Bromoindirubin-3′-Oxime Activates Proteostatic Modules, Reprograms Cellular Bioenergetic Pathways, and Exerts Antiaging Effects

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Lability of the Nrf2/Keap/ARE Cell Defense System in Different Models of Cell Aging and Age-Related Pathologies

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Implication of Adult Hippocampal Neurogenesis in Alzheimer’s Disease and Potential Therapeutic Approaches

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Molecular mechanisms of heart failure: insights from Drosophila

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Vitexin and isovitexin delayed ageing and enhanced stress-resistance through the activation of the SKN-1/Nrf2 signaling pathway

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ALKBH7 mediates necrosis via rewiring of glyoxal metabolism

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Redox-dependent induction of antioxidant defenses by phenolic diterpenes confers stress tolerance in normal human skin fibroblasts: Insights on replicative senescence

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Functional wiring of proteostatic and mitostatic modules ensures transient organismal survival during imbalanced mitochondrial dynamics

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Deteriorated Stress Response in Stationary-Phase Yeast: Sir2 and Yap1 Are Essential for Hsf1 Activation by Heat Shock and Oxidative Stress, Respectively

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Milder degenerative effects of Carfilzomib vs. Bortezomib in the Drosophila model: a link to clinical adverse events

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Dual Oxidase, a Hydrogen-Peroxide-Producing Enzyme, Regulates Neuronal Oxidative Damage and Animal Lifespan in Drosophila melanogaster

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Intensity, Duration, and Context Dependency of the Responses to Nutrient Surplus and Deprivation Signaling in the Heart: Insights Into the Complexities of Cardioprotection

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Preserving transcriptional stress responses as an anti‐aging strategy

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Food for healthier aging: power on your plate

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A PI3K-calcium-Nox axis primes leukocyte Nrf2 to boost immune resilience and limit collateral damage

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Polyoxidovanadates as a pharmacological option against brain aging

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Cytotoxicity models of Huntington’s disease and relevance of hormetic mechanisms: A critical assessment of experimental approaches and strategies

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Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

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Mechanisms of Action of Curcumin on Aging

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Context-Dependent Regulation of Nrf2/ARE Axis on Vascular Cell Function during Hyperglycemic Condition

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Inflammasomes in Alzheimer’s Progression: Nrf2 as a Preventive Target

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HSF1 Regulation in Aging and Its Role in Longevity

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Consumer preference for cement brands used in concrete production: the Ghanaian perspective

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A cell-based assay system for activators of the environmental cell stress response

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An Update on the Molecular Pillars of Aging

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Arm-Gal4 inheritance influences development and lifespan in Drosophila melanogaster.

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Drosophila Models of Cardiac Aging and Disease

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USE OF PROBIOTICS TO INCREASE THE PRODUCTIVE QUALITIES OF FARM ANIMALS

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3,5‐Dicaffeoylquinic Acid Delayed Aging and Promoted Oxidative Stress Tolerance via Activation of the SKN ‐1/Nrf2 Signaling Pathway

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Characterization of the gene expression changes associated with the age-related Smurf phenotype in Drosophila melanogaster

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Insect CncC: Roles in Redox Homeostasis, Physiology, and Insecticide Resistance, with Prospects for Biotechnological Applications

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Preserving transcriptional stress responses as an anti‐aging strategy

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Identification and characterization of proteins withnovel functions in Nrf2 signaling

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Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulation

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Lability of the Nrf2/Keap/ARE Cell Defense System in Different Models of Cell Aging and Age-Related Pathologies

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The Role of the Nrf2 Dimerization Partner Maf-S in Drosophila Gene Regulation, Stress Response and Aging

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